$390 Find Cheap Flights from Wilmington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Bogotá
Bogotá1 stop$582
Santiago
Santiago2 stops$1,130
Quito
Quito2 stops$753
Bogotá
Bogotá1 stop$582
Santiago
Santiago2 stops$1,130
Quito
Quito2 stops$753

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
1:06 pm - 10:00 pm
ILM
-
BOG
9h 54m
1 stop
United Airlines Logo
8:30 am - 3:37 pm
BOG
-
ILM
30h 07m
2 stops
$582United Airlines
Tue, Jul 14 - Tue, Jul 28
American Airlines Logo
2:49 pm - 11:48 pm
ILM
-
MDE
9h 59m
2 stops
American Airlines Logo
12:30 am - 3:15 pm
MDE
-
ILM
13h 45m
2 stops
$586American Airlines
Tue, Jul 14 - Tue, Jul 28
American Airlines Logo
6:00 am - 11:48 pm
ILM
-
MDE
18h 48m
1 stop
American Airlines Logo
12:30 am - 3:15 pm
MDE
-
ILM
13h 45m
2 stops
$596American Airlines
Mon, Nov 9 - Thu, Nov 12
LATAM Airlines Logo
6:00 am - 8:35 pm
ILM
-
MDE
14h 35m
2 stops
LATAM Airlines Logo
7:20 am - 9:37 am
MDE
-
ILM
26h 17m
2 stops
$734LATAM Airlines
Wed, Jul 8 - Wed, Jul 15
Delta Logo
6:48 pm - 7:05 pm
ILM
-
UIO
25h 17m
2 stops
Delta Logo
6:50 pm - 1:43 pm
UIO
-
ILM
17h 53m
2 stops
$753Delta
Mon, Nov 9 - Thu, Nov 12
LATAM Airlines Logo
6:00 am - 8:35 pm
ILM
-
MDE
14h 35m
2 stops
LATAM Airlines Logo
8:25 am - 9:37 am
MDE
-
ILM
25h 12m
2 stops
$783LATAM Airlines
Wed, Jul 8 - Wed, Jul 15
GOL Logo
7:52 pm - 10:12 pm
ILM
-
UIO
27h 20m
2 stops
GOL Logo
6:00 am - 11:59 pm
UIO
-
ILM
16h 59m
1 stop
$792GOL
Sat, Jul 11 - Mon, Jul 20
GOL Logo
8:12 pm - 11:58 pm
ILM
-
UIO
28h 46m
1 stop
GOL Logo
11:59 pm - 2:04 pm
UIO
-
ILM
13h 05m
2 stops
$910GOL
Wed, Jun 10 - Tue, Jun 30
Multiple Airlines Logo
3:41 pm - 9:40 am
ILM
-
GRU
16h 59m
1 stop
Multiple Airlines Logo
9:30 pm - 11:44 pm
GRU
-
ILM
27h 14m
2 stops
$1,056Multiple Airlines
Tue, Aug 11 - Tue, Aug 25
Delta Logo
2:29 pm - 9:45 am
ILM
-
EZE
18h 16m
1 stop
Delta Logo
8:10 pm - 9:55 am
EZE
-
ILM
14h 45m
1 stop
$1,097Delta
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Wilmington to South America were found on United Airlines ($582) and American Airlines ($631).

Good to know

Cheapest flight$341
Flight from Wilmington to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8452 reviews
7.8Entertainment
8.5Crew
7.2Food
7.8Comfort
8.1Boarding
Airline reviews

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

6.0 GoodRafiq, May 2026
ATL - GSP
Read more Delta reviews

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

Flight was delayed an no one cares, or try to help passengers to get the conexión.

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

Airlines should be prohibited from using the seats they get away with.

Got home at 3am after deboarding the plane. No compensation offered by American

The "on the ground" A/C was not working. It was so hot while waiting to get in the air, a passenger from the rear of the plan declared "I just can't!" and waited in the gangway until time to close the doors. It was miserable. But the crew were champs and had an amazing attitude. I know they were as miserable as we were but didn't let that affect their performance.

When I booked my flight a month ago - I selected a seat. That seat was NOT the one I ended up with when I checked into my flight the day before. This is the second time this has occurred. So, I checked my next flight on Wednesday and Thursday and no seat was assigned. Poor, very poor customer service.

Cleared standby and gave up my seat. Terrible policy and boarding experience

Message about flight cancelation was received late due to being in the air. No explanation, just canceled and booked on morning flight. We had to stay in the airport overnight because there was no transportation offered to get to the hotel that AA had available. Actual inflight was fine.

Ceiling fell down and had to have maintenance come and duct tape it up. No WiFi on the flight.

Everything you need to know for your flight to South America

Information on your arrival and departure airports