$453 Find Cheap Flights from Wilmington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago1 stop$754
Quito
Quito1 stop$636
Santiago
Santiago1 stop$754
Quito
Quito1 stop$636

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

Wed, Jan 14 - Thu, Jan 22
American Airlines Logo
6:00 am - 8:16 pmILM-UIO
14h 16m1 stop
American Airlines Logo
7:04 am - 11:57 pmUIO-ILM
16h 53m1 stop
$636American Airlines
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Wed, Jan 14 - Thu, Jan 22
American Airlines Logo
6:00 am - 8:16 pmILM-UIO
14h 16m2 stops
American Airlines Logo
7:04 am - 6:53 pmUIO-ILM
11h 49m1 stop
$640American Airlines
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Mon, Feb 2 - Fri, Feb 6
LATAM Airlines Logo
10:18 am - 11:30 pmILM-MDE
13h 12m2 stops
LATAM Airlines Logo
6:00 am - 11:51 pmMDE-ILM
17h 51m2 stops
$685LATAM Airlines
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Mon, Feb 2 - Fri, Feb 6
LATAM Airlines Logo
6:00 am - 11:30 pmILM-MDE
17h 30m2 stops
LATAM Airlines Logo
6:00 am - 11:51 pmMDE-ILM
17h 51m2 stops
$686LATAM Airlines
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Mon, Feb 9 - Fri, Feb 13
Delta Logo
5:41 pm - 2:05 pmILM-UIO
20h 24m2 stops
Delta Logo
11:45 pm - 10:59 amUIO-ILM
11h 14m1 stop
$750Delta
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Mon, Feb 9 - Fri, Feb 13
Delta Logo
10:18 am - 9:35 pmILM-UIO
11h 17m1 stop
Delta Logo
11:45 pm - 10:59 amUIO-ILM
11h 14m1 stop
$825Delta
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Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
8:15 am - 3:50 pmILM-EZE
29h 35m2 stops
Multiple Airlines Logo
11:15 am - 5:32 pmEZE-ILM
32h 17m3 stops
$965Multiple Airlines
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Thu, Jan 22 - Sun, Feb 1
United Airlines Logo
6:00 am - 9:20 amILM-EZE
25h 20m2 stops
United Airlines Logo
11:55 pm - 11:57 pmEZE-ILM
26h 02m2 stops
$1,020United Airlines
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Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
8:15 am - 3:50 pmILM-EZE
29h 35m2 stops
Multiple Airlines Logo
4:55 pm - 12:25 pmEZE-ILM
21h 30m2 stops
$1,040Multiple Airlines
Find Deal
Mon, Jan 19 - Mon, Jan 26
United Airlines Logo
6:00 am - 7:20 amILM-EZE
23h 20m2 stops
United Airlines Logo
11:55 pm - 11:57 pmEZE-ILM
26h 02m2 stops
$1,055United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Wilmington and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Wilmington to South America.

There are 2 airlines that fly nonstop from Wilmington to South America. They are American Airlines and Delta. The cheapest airline for this route is Delta, with the best round-trip deal found costing $454 and arriving in Lima (LIM). On average, American Airlines offers the best prices for nonstop flights between Wilmington and South America.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Wilmington to South America were found on Delta ($618) and American Airlines ($636).

Good to know

Cheapest flight$453
Flight from Wilmington to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $748 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $799.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8011 reviews
7.9Entertainment
8.1Boarding
8.5Crew
7.9Comfort
7.3Food
Airline reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

4.0 OkayCarl, Dec 2025FLL - LGA
Read more Delta reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

You can plug your phone in & use their wifi to watch movies, etc, but the plane’s wifi was disconnected for most of the flight.

The trip was smooth but the crew were very abrupt, snatching things before finished and being quite snappy when asked questions.

Very below average , plane from Dallas to Toyko was very poor designed plane. I had to sit for 13 hours next to fat man. Really bad seat and entertainment screen sucked

Boarding: Boarding was a bit of a mess. Our tickets indicated "BC" for Business Class, but we and many others were confused as that was not indicated anywhere in the airport, so we didn't know when we're supposed to board. The airplane: The airplane was nice. However, we sat near the back of the business class cabin and the flight attendants and passengers from other cabins would constantly move the curtain (which was very loud), preventing me from fallling asleep on my 8 hour flight. The flight crew: Amazing, generally. However, they nearly forgot to serve breakfast to me. The flight food: I was able to select my meal for dinner, which was really good. Breakfast was a bit of a mess, however. The crew forgot to serve me breakfast until the last minute. Very little was available by the time they remembered. The entertainment: Paltry, underwhelming, and dated. Not one new movie was available. Bottom line: For the money, you might want to consider other options for your international business class flights.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

Everything you need to know for your flight to South America

Information on your arrival and departure airports