$326 Find Cheap Flights from Wilmington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Bogotá
Bogotá2 stops$559
Santiago
Santiago2 stops$952
Quito
Quito2 stops$642
Bogotá
Bogotá2 stops$559
Santiago
Santiago2 stops$952
Quito
Quito2 stops$642

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

Tue, Aug 11 - Mon, Aug 17
United Airlines Logo
4:44 pm - 10:00 pm
ILM
-
BOG
30h 16m
2 stops
United Airlines Logo
12:14 am - 3:37 pm
BOG
-
ILM
38h 23m
2 stops
$559United Airlines
Tue, Aug 11 - Tue, Aug 18
United Airlines Logo
4:44 pm - 4:54 am
ILM
-
BOG
13h 10m
2 stops
United Airlines Logo
7:20 am - 11:57 pm
BOG
-
ILM
15h 37m
1 stop
$625United Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:00 am - 8:15 pm
ILM
-
MDE
15h 15m
1 stop
American Airlines Logo
1:53 pm - 11:51 pm
MDE
-
ILM
8h 58m
1 stop
$641American Airlines
Thu, Dec 24 - Thu, Jan 7
LATAM Airlines Logo
6:00 am - 6:42 pm
ILM
-
UIO
12h 42m
2 stops
LATAM Airlines Logo
8:45 am - 11:04 pm
UIO
-
ILM
14h 19m
2 stops
$642LATAM Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
7:13 pm - 12:48 pm
ILM
-
MDE
18h 35m
2 stops
American Airlines Logo
1:53 pm - 11:51 pm
MDE
-
ILM
8h 58m
1 stop
$646American Airlines
Thu, Dec 24 - Fri, Jan 8
LATAM Airlines Logo
6:00 am - 6:42 pm
ILM
-
UIO
12h 42m
2 stops
LATAM Airlines Logo
8:45 am - 11:04 pm
UIO
-
ILM
14h 19m
2 stops
$662LATAM Airlines
Wed, Dec 23 - Thu, Jan 7
LATAM Airlines Logo
5:45 pm - 6:42 pm
ILM
-
UIO
24h 57m
2 stops
LATAM Airlines Logo
8:45 am - 11:04 pm
UIO
-
ILM
14h 19m
2 stops
$667LATAM Airlines
Mon, Nov 30 - Mon, Mar 1
American Airlines Logo
4:11 pm - 9:00 am
ILM
-
SCL
14h 49m
2 stops
American Airlines Logo
11:45 pm - 5:48 pm
SCL
-
ILM
20h 03m
2 stops
$952American Airlines
Mon, Nov 30 - Mon, Mar 1
American Airlines Logo
6:00 am - 9:00 am
ILM
-
SCL
25h 00m
1 stop
American Airlines Logo
10:15 pm - 7:09 pm
SCL
-
ILM
22h 54m
1 stop
$956American Airlines
Wed, Dec 2 - Sun, Dec 6
United Airlines Logo
3:48 pm - 10:20 am
ILM
-
GRU
16h 32m
2 stops
United Airlines Logo
10:25 pm - 3:28 pm
GRU
-
ILM
19h 03m
2 stops
$980United Airlines
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Wilmington to South America were found on American Airlines ($641) and LATAM Airlines ($642).

Good to know

Cheapest flight$326
Flight from Wilmington to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8455 reviews
8.1Boarding
7.8Entertainment
8.5Crew
7.2Food
7.8Comfort
Airline reviews

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

2.0 MediocreAnonymous, Jun 2026
RDU - LGA
Read more Delta reviews

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

Two delays on two separate planes with parts they could not easily find and replace.

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

On time flight. Seat comfort could be better in the Comfort section.

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Check in for 5am flight at RDU was hampered by American check in counters being seriously understaffed , was told even supervisor called out. Took so long in line for special services check in that we missed our 5am departure even after arriving at 3:30am. Had to be rescheduled to later flight from Charlotte to St Thomas.

Awfully rude American worker at door when we started boarding flight. Then, walk into a blazing hot airplane with no air conditioning until twenty minutes into the flight. Free entertainment was non existent! My husband, along with the fellow passenger in our row, and I could not get entertainment to work, no WIFI! Really?? Been flying American a long time. Was very disappointed.

Two hours delay, probably one hour because they didn’t bring catering and they had to bring water in board. There a change of aircraft. But delays galore at CLT so it must be a CLT and/or AA operation issue. The 1 hr additional delays because nobody could bring 2 packs of water sooner is probably the best example of this airline operates

Our flight was repeatedly delayed for maintenance problems: scheduled for 9.30am, eventually delayed to 7pm! Very very inconvenient! AA should have provided a substitute plane much earlier.. On the other hand, Customer Service crew in Charlotte helped us to reach NY (LGA) by late afternoon. Thank you Patricia!! The actual flight was quick and very comfortable. As always a. excellent, professional crew. [no food on a a short hop).

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

It was late, then the bathroom was inoperable plus it was very hot as well. Plane was very old

Overall, I had a great flight on American Airlines. The only compliant that I have is that my gate changed 30 minutes before boarding the flight. This was annoying because I had a connection in Charlotte and it's a very big airport.

Our flight was delayed 45 minutes and we missed our connection, while we were able to get a flight the following day the voucher for food did not work.

Everything you need to know for your flight to South America

Information on your arrival and departure airports