$319 Find Cheap Flights from Wilmington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Bogotá
Bogotá2 stops$608
Santiago
Santiago2 stops$861
Quito
Quito2 stops$862
Bogotá
Bogotá2 stops$608
Santiago
Santiago2 stops$861
Quito
Quito2 stops$862

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

Sun, May 24 - Mon, Jun 1
Multiple Airlines Logo
4:30 pm - 1:00 pm
ILM
-
MDE
21h 30m
1 stop
Multiple Airlines Logo
1:55 pm - 2:58 pm
MDE
-
ILM
24h 03m
1 stop
$481Multiple Airlines
Fri, May 22 - Mon, Jun 1
Multiple Airlines Logo
2:35 pm - 1:00 pm
ILM
-
MDE
23h 25m
1 stop
Multiple Airlines Logo
1:55 pm - 2:58 pm
MDE
-
ILM
24h 03m
1 stop
$492Multiple Airlines
Sun, May 24 - Mon, Jun 1
Multiple Airlines Logo
8:20 pm - 10:55 am
ILM
-
MDE
15h 35m
2 stops
Multiple Airlines Logo
1:55 pm - 2:58 pm
MDE
-
ILM
24h 03m
1 stop
$530Multiple Airlines
Sun, May 24 - Mon, Jun 1
United Airlines Logo
4:03 pm - 9:10 pm
ILM
-
MDE
30h 07m
2 stops
United Airlines Logo
9:45 am - 3:24 pm
MDE
-
ILM
28h 39m
2 stops
$535United Airlines
Sat, May 23 - Mon, Jun 1
United Airlines Logo
4:05 pm - 9:10 pm
ILM
-
MDE
30h 05m
2 stops
United Airlines Logo
9:45 am - 3:24 pm
MDE
-
ILM
28h 39m
2 stops
$539United Airlines
Sun, May 24 - Tue, Jun 2
Multiple Airlines Logo
8:20 pm - 10:55 am
ILM
-
MDE
15h 35m
2 stops
Multiple Airlines Logo
6:35 am - 2:58 pm
MDE
-
ILM
7h 23m
1 stop
$551Multiple Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:00 am - 8:00 pm
ILM
-
MDE
15h 00m
1 stop
American Airlines Logo
3:05 pm - 11:18 pm
MDE
-
ILM
7h 13m
1 stop
$561American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
7:18 am - 8:00 pm
ILM
-
MDE
13h 42m
2 stops
American Airlines Logo
3:05 pm - 11:18 pm
MDE
-
ILM
7h 13m
1 stop
$566American Airlines
Tue, Aug 25 - Thu, Aug 27
LATAM Airlines Logo
6:00 am - 7:15 pm
ILM
-
BOG
14h 15m
1 stop
LATAM Airlines Logo
2:55 pm - 9:42 am
BOG
-
ILM
17h 47m
1 stop
$627LATAM Airlines
Tue, Aug 25 - Thu, Aug 27
LATAM Airlines Logo
6:00 am - 1:40 pm
ILM
-
BOG
8h 40m
1 stop
LATAM Airlines Logo
11:00 am - 11:09 pm
BOG
-
ILM
11h 09m
2 stops
$632LATAM Airlines
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Wilmington to South America were found on United Airlines ($535) and LATAM Airlines ($627).

Good to know

Cheapest flight$319
Flight from Wilmington to Quito

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8358 reviews
7.9Comfort
8.1Boarding
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

8.0 ExcellentLorna, Mar 2026
LAX - LIH
Read more Delta reviews

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

The flight was delayed 90 minutes The Gate was wrong The Restroom on Aircraft was not clean There was a half used water bottle in my seat

Delta is always a wonderful experience. A clean plane and the crew is really friendly.

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

I am still at the Airport! Delayed Delayed and Delyaed

Ceiling fell down and had to have maintenance come and duct tape it up. No WiFi on the flight.

I appreciate that I finally got the seat I paid extra for this time. Thank you

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

Plane from partner PSA was filthy. Plastic needs to be thoroughly cleaned. Really disgusting to look at and wonder about cleanliness of parts less visible.

Arrived early picked up my bag in a few minutes- great trip - thank you

I like that the flight attendant was very attentive and helpful. The meal menu could have more of an variety of food choices.

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

Didn't get a seat assignment until the last minute even though i picked a seat.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Everything you need to know for your flight to South America

Information on your arrival and departure airports