$158 Find Cheap Flights from Wilmington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Bogotá
Bogotá1 stop$582
Santiago
Santiago1 stop$955
Quito
Quito2 stops$642
Bogotá
Bogotá1 stop$582
Santiago
Santiago1 stop$955
Quito
Quito2 stops$642

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:00 am - 12:36 pm
ILM
-
MDE
7h 36m
1 stop
American Airlines Logo
3:05 pm - 11:18 pm
MDE
-
ILM
7h 13m
1 stop
$581American Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
7:30 am - 10:00 pm
ILM
-
BOG
15h 30m
1 stop
United Airlines Logo
8:30 am - 3:28 pm
BOG
-
ILM
29h 58m
2 stops
$582United Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:34 pm - 12:36 pm
ILM
-
MDE
19h 02m
2 stops
American Airlines Logo
3:05 pm - 11:18 pm
MDE
-
ILM
7h 13m
1 stop
$586American Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
4:09 pm - 7:20 pm
ILM
-
BOG
28h 11m
2 stops
United Airlines Logo
8:30 am - 3:28 pm
BOG
-
ILM
29h 58m
2 stops
$592United Airlines
Mon, Jun 8 - Wed, Jun 24
LATAM Airlines Logo
2:26 pm - 4:43 am
ILM
-
UIO
15h 17m
2 stops
LATAM Airlines Logo
6:50 pm - 1:41 pm
UIO
-
ILM
17h 51m
2 stops
$642LATAM Airlines
Mon, Jun 8 - Wed, Jun 24
Delta Logo
6:50 pm - 6:59 pm
ILM
-
UIO
25h 09m
1 stop
Delta Logo
6:50 pm - 10:15 pm
UIO
-
ILM
26h 25m
2 stops
$647Delta
Sat, Jun 6 - Thu, Jul 2
Delta Logo
1:15 pm - 4:43 am
ILM
-
UIO
16h 28m
2 stops
Delta Logo
9:00 am - 10:56 pm
UIO
-
ILM
12h 56m
2 stops
$662Delta
Sat, Jun 6 - Thu, Jul 2
LATAM Airlines Logo
4:46 pm - 6:59 pm
ILM
-
UIO
27h 13m
1 stop
LATAM Airlines Logo
9:00 am - 10:56 pm
UIO
-
ILM
12h 56m
2 stops
$696LATAM Airlines
Mon, Jun 1 - Mon, Jun 8
Multiple Airlines Logo
2:35 pm - 4:10 am
ILM
-
GRU
36h 35m
2 stops
Multiple Airlines Logo
11:40 am - 2:58 pm
GRU
-
ILM
28h 18m
1 stop
$846Multiple Airlines
Mon, Jun 1 - Wed, Jun 3
Multiple Airlines Logo
2:35 pm - 12:30 am
ILM
-
GRU
32h 55m
2 stops
Multiple Airlines Logo
11:40 am - 8:42 pm
GRU
-
ILM
34h 02m
1 stop
$878Multiple Airlines
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Wilmington to South America were found on American Airlines ($581) and United Airlines ($582).

Good to know

Cheapest flight$158
Flight from Wilmington to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8456 reviews
8.1Boarding
8.5Crew
7.9Comfort
7.2Food
7.8Entertainment
Airline reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

8.0 ExcellentMatthew, May 2026
OKC - ATL
Read more Delta reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

Airlines should be prohibited from using the seats they get away with.

Got home at 3am after deboarding the plane. No compensation offered by American

The "on the ground" A/C was not working. It was so hot while waiting to get in the air, a passenger from the rear of the plan declared "I just can't!" and waited in the gangway until time to close the doors. It was miserable. But the crew were champs and had an amazing attitude. I know they were as miserable as we were but didn't let that affect their performance.

When I booked my flight a month ago - I selected a seat. That seat was NOT the one I ended up with when I checked into my flight the day before. This is the second time this has occurred. So, I checked my next flight on Wednesday and Thursday and no seat was assigned. Poor, very poor customer service.

Cleared standby and gave up my seat. Terrible policy and boarding experience

Message about flight cancelation was received late due to being in the air. No explanation, just canceled and booked on morning flight. We had to stay in the airport overnight because there was no transportation offered to get to the hotel that AA had available. Actual inflight was fine.

Ceiling fell down and had to have maintenance come and duct tape it up. No WiFi on the flight.

I appreciate that I finally got the seat I paid extra for this time. Thank you

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

Everything you need to know for your flight to South America

Information on your arrival and departure airports