$506 Find Cheap Flights from Wilmington to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Bogotá
Bogotá1 stop$657
Santiago
Santiago1 stop$1,080
Quito
Quito1 stop$753
Bogotá
Bogotá1 stop$657
Santiago
Santiago1 stop$1,080
Quito
Quito1 stop$753

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

Thu, May 7 - Mon, May 11
Multiple Airlines Logo
4:30 pm - 1:00 pm
ILM
-
MDE
21h 30m
1 stop
Multiple Airlines Logo
2:06 pm - 11:08 am
MDE
-
ILM
20h 02m
2 stops
$506Multiple Airlines
Thu, May 7 - Mon, May 11
Multiple Airlines Logo
4:30 pm - 1:00 pm
ILM
-
MDE
21h 30m
1 stop
Multiple Airlines Logo
1:55 pm - 2:58 pm
MDE
-
ILM
24h 03m
1 stop
$523Multiple Airlines
Mon, Jun 8 - Wed, Jul 8
Multiple Airlines Logo
2:25 pm - 1:00 pm
ILM
-
MDE
23h 35m
1 stop
Multiple Airlines Logo
2:00 pm - 8:42 pm
MDE
-
ILM
29h 42m
1 stop
$562Multiple Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:00 am - 8:00 pm
ILM
-
MDE
15h 00m
1 stop
American Airlines Logo
3:05 pm - 11:18 pm
MDE
-
ILM
7h 13m
1 stop
$581American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
7:18 am - 8:00 pm
ILM
-
MDE
13h 42m
2 stops
American Airlines Logo
3:05 pm - 11:18 pm
MDE
-
ILM
7h 13m
1 stop
$586American Airlines
Thu, May 28 - Sun, May 31
LATAM Airlines Logo
6:00 am - 7:15 pm
ILM
-
BOG
14h 15m
1 stop
LATAM Airlines Logo
9:00 am - 11:24 pm
BOG
-
ILM
13h 24m
1 stop
$657LATAM Airlines
Thu, May 28 - Sun, May 31
LATAM Airlines Logo
6:18 pm - 8:10 pm
ILM
-
BOG
26h 52m
2 stops
LATAM Airlines Logo
9:00 am - 11:24 pm
BOG
-
ILM
13h 24m
1 stop
$672LATAM Airlines
Wed, Jul 1 - Tue, Jul 14
United Airlines Logo
4:05 pm - 5:00 am
ILM
-
UIO
37h 55m
2 stops
United Airlines Logo
12:35 am - 3:24 pm
UIO
-
ILM
37h 49m
2 stops
$870United Airlines
Thu, May 28 - Sun, May 31
United Airlines Logo
4:05 pm - 4:54 am
ILM
-
BOG
13h 49m
2 stops
United Airlines Logo
11:10 pm - 3:24 pm
BOG
-
ILM
15h 14m
2 stops
$1,017United Airlines
Thu, Jun 4 - Thu, Jun 11
Delta Logo
6:00 am - 5:40 am
ILM
-
GRU
22h 40m
1 stop
Delta Logo
10:50 pm - 10:56 pm
GRU
-
ILM
25h 06m
1 stop
$1,154Delta
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Wilmington to South America were found on American Airlines ($581) and LATAM Airlines ($657).

Good to know

Cheapest flight$506
Flight from Wilmington to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8409 reviews
7.2Food
8.5Crew
7.8Entertainment
8.1Boarding
7.9Comfort
Airline reviews

Boarding was good. The flight was on time ( arrival was 20 minutes early). Inflight service was average ( US airlines have not mastered the skills of customer service yet). The food was mediocre. “ breakfast “ was downright awful and insulting. It was a piece of dough with mon descript filling that was supposed to be cheese omelette).

6.0 GoodAnonymous, Apr 2026
DTW - AMS
Read more Delta reviews

Boarding was good. The flight was on time ( arrival was 20 minutes early). Inflight service was average ( US airlines have not mastered the skills of customer service yet). The food was mediocre. “ breakfast “ was downright awful and insulting. It was a piece of dough with mon descript filling that was supposed to be cheese omelette).

The tray table was broken and the food was terrible.

The gentleman at the gate I think his name is RIE was exceptional

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

Crew was great. Near on time departure and early arrival. Snacks are always meh. Not a fan of the "pay for everything including miles " proposal unless base flight rate going to be 100 bucks.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

Overall Good! The weather delayed our takeoff from Atlanta and our arrival in Miami! If Mother Nature can mess up a flight she will do it every time!

The flight was smooth, the crew was great but the plane was quite old

When I booked my flight a month ago - I selected a seat. That seat was NOT the one I ended up with when I checked into my flight the day before. This is the second time this has occurred. So, I checked my next flight on Wednesday and Thursday and no seat was assigned. Poor, very poor customer service.

Cleared standby and gave up my seat. Terrible policy and boarding experience

Message about flight cancelation was received late due to being in the air. No explanation, just canceled and booked on morning flight. We had to stay in the airport overnight because there was no transportation offered to get to the hotel that AA had available. Actual inflight was fine.

Ceiling fell down and had to have maintenance come and duct tape it up. No WiFi on the flight.

I appreciate that I finally got the seat I paid extra for this time. Thank you

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

Plane from partner PSA was filthy. Plastic needs to be thoroughly cleaned. Really disgusting to look at and wonder about cleanliness of parts less visible.

Arrived early picked up my bag in a few minutes- great trip - thank you

I like that the flight attendant was very attentive and helpful. The meal menu could have more of an variety of food choices.

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

Everything you need to know for your flight to South America

Information on your arrival and departure airports