$450 Find Cheap Flights from Wilmington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Wilmington to South America departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Wilmington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago1 stop$903
Quito
Quito1 stop$673
Santiago
Santiago1 stop$903
Quito
Quito1 stop$673

Book Cheap Wilmington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Wilmington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Wilmington to South America

vie., may. 22 - dom., may. 31
Multiple Airlines Logo
3:39 pm - 1:08 pm
ILM
-
MDE
22h 29m
1 stop
Multiple Airlines Logo
2:06 pm - 8:09 pm
MDE
-
ILM
29h 03m
1 stop
$494Multiple Airlines
vie., may. 22 - dom., may. 31
Multiple Airlines Logo
3:39 pm - 1:08 pm
ILM
-
MDE
22h 29m
1 stop
Multiple Airlines Logo
10:15 pm - 10:58 am
MDE
-
ILM
35h 43m
2 stops
$535Multiple Airlines
mié., abr. 22 - dom., may. 10
American Airlines Logo
6:41 am - 8:15 pm
ILM
-
MDE
14h 34m
2 stops
American Airlines Logo
1:53 pm - 11:57 pm
MDE
-
ILM
9h 04m
1 stop
$576American Airlines
sáb., may. 23 - dom., may. 31
American Airlines Logo
7:20 pm - 12:53 pm
ILM
-
MDE
18h 33m
1 stop
American Airlines Logo
6:00 am - 7:22 pm
MDE
-
ILM
12h 22m
1 stop
$586American Airlines
mar., may. 19 - lun., may. 25
Multiple Airlines Logo
10:36 am - 9:49 am
ILM
-
MDE
24h 13m
1 stop
Multiple Airlines Logo
12:40 pm - 2:48 pm
MDE
-
ILM
25h 08m
2 stops
$587Multiple Airlines
vie., abr. 24 - mar., abr. 28
LATAM Airlines Logo
5:50 pm - 4:43 am
ILM
-
UIO
11h 53m
2 stops
LATAM Airlines Logo
6:50 pm - 1:38 pm
UIO
-
ILM
17h 48m
2 stops
$746LATAM Airlines
vie., abr. 24 - lun., abr. 27
LATAM Airlines Logo
5:50 pm - 4:43 am
ILM
-
UIO
11h 53m
2 stops
LATAM Airlines Logo
12:59 am - 1:38 pm
UIO
-
ILM
11h 39m
1 stop
$833LATAM Airlines
lun., mar. 16 - mar., mar. 31
Delta Logo
10:10 am - 7:40 am
ILM
-
SCL
20h 30m
1 stop
Delta Logo
8:55 pm - 1:38 pm
SCL
-
ILM
17h 43m
2 stops
$903Delta
jue., ago. 13 - lun., ago. 17
United Airlines Logo
1:03 pm - 9:30 am
ILM
-
GRU
19h 27m
2 stops
United Airlines Logo
9:30 pm - 12:05 pm
GRU
-
ILM
39h 35m
2 stops
$1,163United Airlines
lun., mar. 16 - mié., mar. 18
United Airlines Logo
6:00 am - 5:40 am
ILM
-
VCP
22h 40m
2 stops
United Airlines Logo
10:45 pm - 4:18 pm
VCP
-
ILM
18h 33m
2 stops
$7,035United Airlines
Booking Insights

KAYAK's insights & trends for Wilmington to South America flights

Get data-powered insights and trends into flights from Wilmington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Wilmington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Wilmington to South America were found on American Airlines ($576) and LATAM Airlines ($746).

Good to know

Cheapest flight$450
Flight from Wilmington to Buenos Aires

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Wilmington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Wilmington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Wilmington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Wilmington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Wilmington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Wilmington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Wilmington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Wilmington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Wilmington to South America

 
Need help choosing which airline to fly with from Wilmington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8215 reviews
8.5Crew
7.9Comfort
8.1Boarding
7.8Entertainment
7.2Food
Airline reviews

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

2.0 MediocreCason, Feb 2026
EWR - ATL
Read more Delta reviews

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

The staff was frielndly. The plane was terrible, it was too small and should be decommissioned. There were no back seat screens at all. The only beverages we had a choice from was coffee, tea or water. The only bathroom in the back was behind the flight attendant's jump seat and wasn't working. And I literally felt like I was sitting on top of the guy next to me. It was terribly hot in the plane and we had to sit on the tarmac in Chicago for 1/2 hour due to congestion in Mpls. Wouldn't they have know that before they even boarded us so that we could have sat in comfort in the terminal?

Never got on it. Was re-routed through Detroit and am still in airports 12 hours later waiting for my connecting plane to arrive.

Delta has too many delays now days. It is 1:06 am now. I was supposed to land in Norfolk at 10:30 pm. I got re-booked through Detroit and I’m still in Detroit. I hope to be landed in Norfolk by 3am. I’ve been in airports for 12 hours as of right now. There is a weather delay now but most delays lately have been maintenance.

Very Very late. Subsequent flights left an hour before ours

This is my worse experience with Delta. My colleagues and I were traveling to ICT for work. Usually we connect in Dallas, but this year we decided to book with Delta and connect in Atlanta. We were excited to fly with Delta because we hear great things and Delta is one of my top choices when choosing an airline for travel. On the connecting flights to and from Wichita/Atlanta - it felt hot and uncomfortable on the plane. The plane to ICT was smaller and older and did not have any wi-fi or entertainment. The most terrible experience was at boarding in Atlanta both times traveling to Wichita and then back to Tampa. First on our flight from ATL to ICT - the attendant scanning our boarding pass made us go back to the line when we went up to scan our passes to wait. After a few minutes, she allowed us to come back up to scan but then she asked what boarding zone we were. We told her zone 5, and since we were standing on the wrong side of the small rope partition, she made us go back to stand on the right side. There was another gentleman that came up to board and scan his pass, and she mentioned he was also on the wrong side but she let him go through. Our group had to walk back and forth for no reason, causing an unnecessary delay to board the plane. We have never experienced anything like this, especially when the boarding area was completely empty and everyone already boarded since boarding was earlier than the original boarding time. On our flight from ATL to TPA, the attendants scanning our boarding passes had us scan our passes twice, not explaining to us what was going on. They automatically started tagging our carry on bags and did not explain to us or tell us what was going on and why this was happening. Obviously we knew our bags were being forced to check in but with no reason. There was no announcement or mention and I have never had anyone force me to check in my bag before boarding the plane. We assumed the overhead bins were full but when we boarded the plane, there was a lot of empty bins and a lot of spaces to put our bags. We all were disappointed and frustrated with Delta and will be hesitant to fly Delta again or anytime soon.

Boarding and crew were fantastic, but I paid for a window seat with no window. Seat 11D on a CRJ-900 apparently does not have a window. Lesson learned.

Terrible. Four hour delay because Delta could not find crew to man the aircraft. Terrible communication. Terrible insight into the delays. One of the worst flight experiences I’ve had.

It was good. The leg room was not great in Row 1.

I like that the flight attendant was very attentive and helpful. The meal menu could have more of an variety of food choices.

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

Didn't get a seat assignment until the last minute even though i picked a seat.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

2 hour delay due to equipment failure. No updates via the app and airport screens (which continued to show a departure time in the past). AA eventually switched planes and the new plane was not catered or cleaned correctly.

Could we please end the loud announcements about credit card offers on your flights? We are trying to sleep, work, watch videos, etc. and if we need a credit card, we will ask for one. Flying is already not what it used to be.

Bags took over and hour to come out. Delays due to wind caused rebooking.

Lower WiFi prices; allow us to see our flight on a map; more variety of drink choices.

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

Everything you need to know for your flight to South America

Information on your arrival and departure airports