United States
USD

Panama City 5 Star Hotels

Search hundreds of travel sites at once for 5 star hotels in Panama City

Here is why travelers choose KAYAK

Free to useThere are no hidden charges or fees.

Filter your dealsFilter by free cancellation, free breakfast and more.

Millions of reviewsCheck ratings based on millions of real guest reviews.

Recommended by KAYAK
Booking Insights
Recommended by KAYAK

Best Panama City 5 star hotels

These are the best prices for Oct 13 - 20.
Riu Plaza Panama - Panama City - Bedroom
Riu Plaza Panama
Bella Vista
8.7Very good(7751)
Free Wi-Fi
Pool
Spa
$157+
Check availability
Megapolis Hotel Panama - Panama City - Outdoors view
Megapolis Hotel Panama
San Francisco
8.5Very good(3701)
Parking
Free Wi-Fi
Pool
Spa
$150+
Check availability
Sofitel Legend Casco Viejo - Panama City - Panama City - Lounge
Sofitel Legend Casco Viejo - Panama City
Casco Viejo
9.5Wonderful(595)
Free Wi-Fi
Pool
Spa
$538+
Check availability
Renaissance Panama City Hotel - Panama City - Lobby
Renaissance Panama City Hotel
Bella Vista
8.6Very good(554)
Parking
Free Wi-Fi
Pool
Spa
$166+
Check availability
Hilton Panama - Panama City - Restaurant
Hilton Panama
Bella Vista
8.7Very good(1515)
Pool
Pet friendly
Spa
$322+
Check availability
W Panama - Panama City - Bedroom
W Panama
Bella Vista
8.7Very good(924)
Pool
Pet friendly
Spa
$337+
Check availability
JW Marriott Panama - Panama City - Lobby
JW Marriott Panama
San Francisco
8.9Very good(1887)
Free Wi-Fi
Pool
Pet friendly
$385+
Check availability
Waldorf Astoria Panama - Panama City - Lobby
Waldorf Astoria Panama
Bella Vista
8.7Very good(503)
Free Wi-Fi
Pool
Spa
$360+
Check availability
Hotel Las Americas Golden Tower Panamá - Panama City - Bedroom
Hotel Las Americas Golden Tower Panamá
San Francisco
8.6Very good(2290)
Parking
Free Wi-Fi
Pool
Spa
$172+
Check availability
Gran Evenia Panama - Panama City
Gran Evenia Panama
Bella Vista
8.7Very good(902)
Parking
Free Wi-Fi
Pool
$108+
Check availability
Bristol Panama, a Registry Collection Hotel - Panama City - Living room
Bristol Panama, a Registry Collection Hotel
Bella Vista
9.0Wonderful(1309)
Free Wi-Fi
Pool
Spa
$253+
Check availability
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City - Panama City - Living room
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
9.4Wonderful(723)
Parking
Free Wi-Fi
Pool
Spa
$313+
Check availability
Hyatt Regency Panama City - Panama City - Building
Hyatt Regency Panama City
Bella Vista
9.0Wonderful(236)
Free Wi-Fi
Pool
Pet friendly
Spa
$241+
Check availability
Hotel Bardot Boutique - Panama City
Hotel Bardot Boutique
Casco Viejo
8.4Very good(933)
Free Wi-Fi
$157+
Check availability
Global Hotel Panama - Panama City
Global Hotel Panama
Bella Vista
8.6Very good(3066)
Parking
Free Wi-Fi
Pool
$139+
Check availability
Booking Insights

KAYAK’s insights for 5 star hotels in Panama City

Discover seasonal trends, ideal booking windows, and other data-driven tips to plan your stay in Panama City with confidence.

How much does a 5 star hotel room in Panama City cost?

The average price for a 5 star hotel in Panama City is $216 but this can vary depending on the season and when you’ve booked. In the last 7 days, the cheapest price found on KAYAK was $88 at Gran Evenia Panama.

Which month has the cheapest rates for 5 star hotels?

5 star hotels in Panama City are cheapest in May, with an average rate of $139. On the other hand, they are at their most expensive in August, where the average price is $278.

What is the cheapest day of the week to book a 5 star hotel in Panama City?

The lowest prices can usually be found on Wednesday, where the average nightly price is $127. The most expensive night is generally Thursday, where the average price is $228.

Which neighbourhood do KAYAK users most love to book their 5 star hotel in Panama City?

The most popular neighbourhood in Panama City among KAYAK users to search for a 5 star hotel is Casco Viejo, with an average price of $477. Sofitel Legend Casco Viejo - Panama City, Hotel Casa Panamá, and Central Hotel Panama Casco Viejo rank among the highest-rated hotels in Casco Viejo.

How early should you book a 5 star hotel in Panama City?

Book at least 7 days before your stay begins to get the best price for your Panama City 5 star hotel.

Find deals

Good to know

Low season

High season

Average price (weeknight)

Average price (weekend night)

Lowest hotel price

May
August
$204
$168
$88
Cheapest month to stay with an average 24% drop in price.
Most expensive month to stay with an average 52% rise in price.
Average Sun - Thu price over the last 2 weeks.
Average Fri & Sat price over the last 2 weeks.
The cheapest 5 star hotel room rate in the last 7 days

KAYAK's top tips for finding Panama City 5 star hotel deals

  • Prices for 5 star hotels in Panama City are cheaper in the low season, which is in May and November.
  • 5 star room prices can vary depending on different factors. However, generally rooms cost less on a Wednesday. The most expensive night for a stay is Thursday.
  • The cheapest 5 star hotel room in Panama City found on KAYAK in the last 2 weeks was $92. The most expensive cost $460.

FAQs about Panama City 5 star hotels

  • How many 5 star hotels are there in Panama City?

    Currently, there are around 21 5-star hotels on KAYAK available for you to book.

  • What are the most popular 5 star hotels in Panama City?

    The most popular 5 star hotels among KAYAK users in the last 3 months are Megapolis Hotel Panama, Renaissance Panama City Hotel and Hotel Las Americas Golden Tower Panamá.

  • What are the advantages of booking a 5-star hotel in Panama City?

    A 5-star hotel in Panama City typically includes a wide range of services and facilities, such as 24/7 concierge, gourmet dining, wellness areas like spas and fully equipped gyms, and business centers with meeting rooms. Rooms are usually larger and better appointed, often featuring premium bedding, luxury toiletries, high-end coffee machines, and smart climate controls. For travelers seeking more comfort, privacy, and on-site convenience, a 5-star hotel can be a significant upgrade over more basic accommodation types in Panama City.

Where to stay in a 5 star hotel in Panama City?

Our map will help you find the perfect place to stay in Panama City by showing you the exact location of each hotel.

More options for your stay in Panama City