BUF - PTY

$226 Find Cheap Flights from Buffalo to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Panama City departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$511
American Airlines
to. 1/29to. 2/5
BUF - PTY • 2 stops
Cheapest one-way
$226
United Airlines
ma. 2/23
BUF - PTY • 2 stops
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Buffalo to Panama City (BUF-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Panama City

to., jan. 29 - to., feb. 5
American Airlines Logo
5:12 am - 3:38 pm
BUF
-
PTY
10h 26m2 stops
American Airlines Logo
4:50 pm - 11:21 am
PTY
-
BUF
18h 31m2 stops
$511American Airlines
lø., apr. 25 - lø., mai 2
United Airlines Logo
10:23 am - 7:31 pm
BUF
-
PTY
10h 08m1 stop
United Airlines Logo
10:55 pm - 9:44 am
PTY
-
BUF
9h 49m1 stop
$518United Airlines
lø., jan. 17 - fr., jan. 23
American Airlines Logo
12:35 pm - 1:27 pm
BUF
-
PTY
24h 52m2 stops
American Airlines Logo
4:50 pm - 11:21 am
PTY
-
BUF
18h 31m2 stops
$522American Airlines
ma., feb. 2 - ma., feb. 16
American Airlines Logo
5:12 am - 3:38 pm
BUF
-
PTY
10h 26m2 stops
American Airlines Logo
4:05 pm - 4:00 pm
PTY
-
BUF
23h 55m2 stops
$523American Airlines
to., mar. 19 - ti., mar. 31
United Airlines Logo
10:23 am - 7:02 pm
BUF
-
PTY
9h 39m1 stop
United Airlines Logo
3:30 pm - 4:57 pm
PTY
-
BUF
24h 27m2 stops
$529United Airlines
ma., jan. 12 - to., jan. 15
American Airlines Logo
4:17 pm - 1:27 pm
BUF
-
PTY
21h 10m2 stops
American Airlines Logo
2:27 pm - 12:08 pm
PTY
-
BUF
21h 41m2 stops
$540American Airlines
to., jan. 29 - to., feb. 5
United Airlines Logo
11:24 am - 8:02 pm
BUF
-
PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 8:29 pm
PTY
-
BUF
27h 48m2 stops
$549United Airlines
ti., feb. 3 - ti., feb. 17
Delta Logo
6:00 am - 1:55 pm
BUF
-
PTY
7h 55m1 stop
Delta Logo
3:20 pm - 11:18 am
PTY
-
BUF
19h 58m1 stop
$555Delta
to., mai 14 - sø., mai 17
American Airlines Logo
8:01 pm - 12:15 pm
BUF
-
PTY
17h 14m2 stops
American Airlines Logo
1:55 pm - 10:46 am
PTY
-
BUF
19h 51m2 stops
$573American Airlines
to., mar. 19 - fr., mar. 27
American Airlines Logo
5:29 pm - 12:22 pm
BUF
-
PTY
19h 53m2 stops
American Airlines Logo
1:39 pm - 10:58 am
PTY
-
BUF
20h 19m2 stops
$597American Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to Panama City flights

Get data-powered insights and trends into flights from Buffalo to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Buffalo and Panama City?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Buffalo to Panama City.

There is just one airline that flies from Buffalo to Panama City direct and that is Delta. The best round-trip deal found from Delta for the route is $497.

Good to know

Low seasonApril
Cheapest flight$226
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 22% increase in price.
Flight from Buffalo to Panama City

When to book flights from Buffalo to Panama City

Are your dates flexible? Find out the best times to travel from Buffalo to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Buffalo to Panama City

  • What is the cheapest flight from Buffalo to Panama City?

    In the last 3 days, the lowest price for a flight from Buffalo to Panama City was $226 for a one-way ticket and $522 for a round-trip.

  • Do I need a passport to fly between Buffalo and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Buffalo and on arrival in Panama City.

  • Which airports will I be using when flying from Buffalo to Panama City?

    On your way to Panama City, you’ll fly out from Buffalo. You’ll be landing at Panama City Tocumen Intl.

  • Which aircraft models fly most regularly from Buffalo to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Buffalo to Panama City?

    SkyTeam is the only airline alliance operating flights between Buffalo and Panama City.

  • How does KAYAK find such low prices on flights from Buffalo to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Buffalo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Buffalo with another airline. Booking your flights between Buffalo and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Buffalo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Buffalo to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8005 reviews
7.9Comfort
8.1Boarding
7.3Food
7.9Entertainment
8.5Crew
Airline reviews

None of the airplane features were available during the flight.

4.0 OkayAnonymous, Dec 2025
JFK - SDQ
Read more Delta reviews

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

I truly love flying with Delta. They have always treated me with the upmost respect

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight was great. The gate location was way to far away!!!

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Everything you need to know for your flight from Buffalo to Panama City

Information on your arrival and departure airports