Which airports can I use when flying from Panama City to Buffalo?

Flights from Panama City to Buffalo usually depart from Panama City Tocumen Intl (PTY) and arrive at Buffalo (BUF).

What cabin classes can I book on flights from Panama City to Buffalo?

Only Economy Class is available on flights from Panama City to Buffalo.

Which airports do connecting flights from Panama City to Buffalo pass through?

Most connecting flights from Panama City to Buffalo pass through Atlanta Hartsfield-Jackson (ATL), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from Panama City to Buffalo?

Yes. Being flexible with your travel dates can save you up to 38% on the Panama City to Buffalo route. Tuesday is the cheapest departure day at $534 round-trip on average, while Monday is the most expensive at $858, a difference of $324. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Panama City to Buffalo?

A nonstop flight from Panama City to Buffalo takes 0h 00m, covering 2,339 miles.

Do I need a passport to fly from Panama City to Buffalo?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Panama City to Buffalo changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $723 to $1,118. That means the highest observed fare was about 54% higher than the lowest one.

How are flight prices from Panama City to Buffalo looking right now?

One-way fares from Panama City to Buffalo are currently higher than usual. Average one-way flight prices are about $398, which is 16% above the typical average for this route.

What is the time difference between Panama City and Buffalo?

Buffalo is 1 hour ahead of Panama City (Eastern Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Buffalo Airport (BUF)?

Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include: • Dollar • Budget • Hertz • Alamo • Thrifty

What is the cheapest airline to fly from Panama City to Buffalo?

United Airlines ($723) and Delta ($745) are the cheapest airlines to fly round-trip from Panama City to Buffalo according to KAYAK data over the last 5 days.

What is the cheapest layover airport when flying from Panama City to Buffalo?

Flights via Atlanta Hartsfield-Jackson (ATL) offer the most affordable fares, with an average round-trip price of $618. Based on KAYAK data over the past 3 months.

When flying from Panama City to Buffalo which airport offers the shortest layover?

Atlanta Hartsfield-Jackson (ATL) had the shortest average connection time for Panama City to Buffalo layovers at 293 minutes over the past 3 months.

$344 CHEAP FLIGHTS from Panama City to Buffalo (PTY - BUF)

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Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$723

Typical prices: $534-$807

United Airlines

Wed 10/24Thu 11/8

PTY - BUF • 2 stops

Cheapest one-way

$344

Typical prices: $338-$420

United Airlines

Fri 1/19

PTY - BUF • 2 stops

Nonstop flights

Not available

There are currently no direct flights between Panama City and Buffalo. You'll need to take a connecting flight to reach the destination.

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Flight Deals

Cheap Flights from Panama City to Buffalo (PTY-BUF)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Panama City to Buffalo

Sat, Oct 24 - Sun, Nov 8

9:45 am - 11:05 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 20m1 stop Newark

6:00 am - 8:02 pmBUF Buffalo-PTY Panama City Tocumen Intl

14h 02m1 stop Newark

$723United Airlines

Sat, Oct 24 - Sun, Nov 8

2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 35m1 stop Atlanta Hartsfield-Jackson

6:00 am - 1:59 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 59m1 stop Atlanta Hartsfield-Jackson

$745Delta

Fri, Oct 23 - Mon, Oct 26

3:30 pm - 9:08 amPTY Panama City Tocumen Intl-BUF Buffalo

16h 38m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

7:52 pm - 7:02 pmBUF Buffalo-PTY Panama City Tocumen Intl

24h 10m2 stops Washington, D.C. Dulles Intl Newark

$746United Airlines

Thu, Oct 1 - Mon, Oct 5

3:30 pm - 4:43 pmPTY Panama City Tocumen Intl-BUF Buffalo

24h 13m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

7:42 pm - 2:14 pmBUF Buffalo-PTY Panama City Tocumen Intl

19h 32m2 stops Newark Houston George Bush Intcntl

$754United Airlines

Sat, Oct 24 - Sun, Nov 8

2:02 pm - 10:48 amPTY Panama City Tocumen Intl-BUF Buffalo

19h 46m2 stops Miami Charlotte Douglas

7:01 pm - 2:13 pmBUF Buffalo-PTY Panama City Tocumen Intl

19h 12m2 stops Philadelphia Miami

$758American Airlines

Thu, Oct 1 - Mon, Oct 5

3:30 pm - 1:11 pmPTY Panama City Tocumen Intl-BUF Buffalo

20h 41m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

5:45 pm - 6:37 pmBUF Buffalo-PTY Panama City Tocumen Intl

25h 52m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$766United Airlines

Thu, Oct 1 - Mon, Oct 5

3:30 pm - 4:43 pmPTY Panama City Tocumen Intl-BUF Buffalo

24h 13m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

6:30 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

14h 01m1 stop Newark

$769United Airlines

Sat, Oct 24 - Sun, Nov 8

9:45 am - 11:05 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 20m1 stop Newark

5:58 pm - 8:02 pmBUF Buffalo-PTY Panama City Tocumen Intl

26h 04m2 stops Chicago O'Hare Intl Newark

$772United Airlines

Thu, Oct 1 - Mon, Oct 5

3:30 pm - 4:43 pmPTY Panama City Tocumen Intl-BUF Buffalo

24h 13m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

7:42 pm - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

24h 49m1 stop Newark

$781United Airlines

Thu, Oct 1 - Mon, Oct 5

3:30 pm - 1:11 pmPTY Panama City Tocumen Intl-BUF Buffalo

20h 41m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

5:45 pm - 6:37 pmBUF Buffalo-PTY Panama City Tocumen Intl

25h 52m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$788United Airlines

Recent last minute flight deals from Panama City to Buffalo

Tue, Sep 15 - Tue, Sep 29

3:30 pm - 9:08 amPTY Panama City Tocumen Intl-BUF Buffalo

16h 38m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

10:30 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

10h 01m1 stop Newark

$727United Airlines

Tue, Sep 15 - Tue, Sep 29

2:23 pm - 11:52 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 29m1 stop Atlanta Hartsfield-Jackson

6:05 am - 12:58 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 53m1 stop Atlanta Hartsfield-Jackson

$788Delta

Tue, Sep 15 - Tue, Sep 29

1:16 pm - 11:39 amPTY Panama City Tocumen Intl-BUF Buffalo

21h 23m2 stops Miami Chicago O'Hare Intl

5:44 pm - 12:26 pmBUF Buffalo-PTY Panama City Tocumen Intl

19h 42m2 stops Washington, D.C. Reagan-National Miami

$818American Airlines

Tue, Sep 15 - Tue, Sep 29

2:23 pm - 11:52 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 29m1 stop Atlanta Hartsfield-Jackson

6:05 am - 12:58 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 53m1 stop Atlanta Hartsfield-Jackson

$874Delta

Tue, Sep 15 - Tue, Sep 29

2:23 pm - 11:52 pmPTY Panama City Tocumen Intl-BUF Buffalo

8h 29m1 stop Atlanta Hartsfield-Jackson

6:05 am - 12:58 pmBUF Buffalo-PTY Panama City Tocumen Intl

7h 53m1 stop Atlanta Hartsfield-Jackson

$930Delta

Tue, Sep 15 - Tue, Sep 29

3:30 pm - 1:16 pmPTY Panama City Tocumen Intl-BUF Buffalo

20h 46m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

7:59 pm - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

24h 32m2 stops Washington, D.C. Dulles Intl Newark

$1,074United Airlines

Tue, Sep 15 - Tue, Sep 29

3:30 pm - 1:16 pmPTY Panama City Tocumen Intl-BUF Buffalo

20h 46m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

10:30 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

10h 01m1 stop Newark

$1,100United Airlines

Tue, Sep 15 - Tue, Sep 29

9:45 am - 11:12 pmPTY Panama City Tocumen Intl-BUF Buffalo

12h 27m1 stop Newark

10:10 am - 7:31 pmBUF Buffalo-PTY Panama City Tocumen Intl

10h 21m2 stops Washington, D.C. Dulles Intl Newark

$1,198United Airlines

Tue, Sep 15 - Tue, Sep 29

3:50 pm - 8:10 amPTY Panama City Tocumen Intl-BUF Buffalo

15h 20m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

7:59 pm - 2:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

19h 56m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl

$1,727Multiple Airlines

Tue, Sep 15 - Tue, Sep 29

10:10 am - 9:08 amPTY Panama City Tocumen Intl-BUF Buffalo

21h 58m2 stops Bogotá El Dorado Chicago O'Hare Intl

7:59 pm - 2:55 pmBUF Buffalo-PTY Panama City Tocumen Intl

19h 56m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl

$1,787Avianca

Booking Insights

Price, demand and travel trends for Panama City to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Panama City to Buffalo with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Panama City to Buffalo?

Round-trip flights from Panama City to Buffalo start at $723. Prices are typical for this route right now, with typical round-trip fares ranging from $534 to $807. The lowest price found in the past 5 days was $723 on United Airlines.

Find deals

Cheapest flight	$344

Flight from Panama City to Buffalo

When to book flights from Panama City to Buffalo

Are your dates flexible? Find out the best times to travel from Panama City to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Panama City to Buffalo?
Flights from Panama City to Buffalo usually depart from Panama City Tocumen Intl (PTY) and arrive at Buffalo (BUF).
What cabin classes can I book on flights from Panama City to Buffalo?
Only Economy Class is available on flights from Panama City to Buffalo.
Which airports do connecting flights from Panama City to Buffalo pass through?
Most connecting flights from Panama City to Buffalo pass through Atlanta Hartsfield-Jackson (ATL), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.
Can I save money by using flexible dates for flights from Panama City to Buffalo?
Yes. Being flexible with your travel dates can save you up to 38% on the Panama City to Buffalo route. Tuesday is the cheapest departure day at $534 round-trip on average, while Monday is the most expensive at $858, a difference of $324. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How long is a flight from Panama City to Buffalo?
A nonstop flight from Panama City to Buffalo takes 0h 00m, covering 2,339 miles.
Do I need a passport to fly from Panama City to Buffalo?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
Have flight prices from Panama City to Buffalo changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $723 to $1,118. That means the highest observed fare was about 54% higher than the lowest one.
How are flight prices from Panama City to Buffalo looking right now?
One-way fares from Panama City to Buffalo are currently higher than usual. Average one-way flight prices are about $398, which is 16% above the typical average for this route.
What is the time difference between Panama City and Buffalo?
Buffalo is 1 hour ahead of Panama City (Eastern Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Buffalo Airport (BUF)?
Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates starting from around $19 for economy cars. Top options include:
• Dollar
• Budget
• Hertz
• Alamo
• Thrifty

If your dates can be flexible, aim for a Tuesday departure instead of Monday. On this route, Tuesday flights average $534 - about $324 less than Monday (38% savings) based on the last 12 months.
If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.
- Aloft Buffalo Airport
- Comfort Inn and Suites Buffalo Airport
- TownePlace Suites by Marriott Buffalo Airport

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PTY - BUF

$344 Find Cheap Flights from Panama City to Buffalo - Compare and Save

Everything you should know

Cheap Flights from Panama City to Buffalo (PTY-BUF)

Recent round-trip flight deals from Panama City to Buffalo

Recent one-way flight deals from Panama City to Buffalo

Recent last minute flight deals from Panama City to Buffalo

Price, demand and travel trends for Panama City to Buffalo flights

How much is a round-trip flight from Panama City to Buffalo?

What is the cheapest airline to fly from Panama City to Buffalo?

What is the cheapest layover airport when flying from Panama City to Buffalo?

When flying from Panama City to Buffalo which airport offers the shortest layover?

Key details for Panama City to Buffalo flights

Cheapest flight

When to book flights from Panama City to Buffalo

Your Panama City to Buffalo flight questions, answered

Your guide to booking Panama City to Buffalo flights

More options for your flight from Panama City to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Panama City to Buffalo

Find direct flights to and from Panama City and Buffalo

Flights from domestic origins to Buffalo

Flights to other popular destinations

Find deals for your return flight