BUF - SCL

$553 Find Cheap Flights from Buffalo to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Santiago departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$826
LATAM Airlines
Tue 3/10Tue 3/17
BUF - SCL • 1 stop
Cheapest one-way
$484
Delta
Thu 2/19
BUF - SCL • 1 stop
Top airlines
LATAM Airlines
Cheapest • from $826 (round-trip)
LATAM Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Buffalo to Santiago (BUF-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Santiago

Tue, Mar 10 - Tue, Mar 17
LATAM Airlines Logo
12:07 pm - 7:40 am
BUF
-
SCL
18h 33m
1 stop
LATAM Airlines Logo
10:25 pm - 11:46 pm
SCL
-
BUF
26h 21m
1 stop
$826LATAM Airlines
Tue, Mar 10 - Tue, Mar 17
LATAM Airlines Logo
7:38 pm - 2:05 pm
BUF
-
SCL
17h 27m
2 stops
LATAM Airlines Logo
10:40 pm - 3:14 pm
SCL
-
BUF
17h 34m
1 stop
$839LATAM Airlines
Tue, Mar 10 - Tue, Mar 17
LATAM Airlines Logo
4:53 pm - 3:30 pm
BUF
-
SCL
21h 37m
2 stops
LATAM Airlines Logo
4:02 pm - 3:14 pm
SCL
-
BUF
24h 12m
2 stops
$860LATAM Airlines
Tue, Mar 10 - Tue, Mar 17
LATAM Airlines Logo
12:07 pm - 2:10 pm
BUF
-
SCL
25h 03m
3 stops
LATAM Airlines Logo
10:25 pm - 3:14 pm
SCL
-
BUF
17h 49m
2 stops
$863LATAM Airlines
Thu, Mar 19 - Mon, Mar 23
LATAM Airlines Logo
3:56 pm - 5:55 am
BUF
-
SCL
12h 59m
1 stop
LATAM Airlines Logo
6:30 pm - 3:58 pm
SCL
-
BUF
22h 28m
2 stops
$873LATAM Airlines
Thu, Apr 2 - Fri, Apr 10
LATAM Airlines Logo
12:07 pm - 7:00 am
BUF
-
SCL
17h 53m
2 stops
LATAM Airlines Logo
8:40 am - 3:14 pm
SCL
-
BUF
30h 34m
3 stops
$903LATAM Airlines
Thu, Apr 2 - Sat, Apr 11
LATAM Airlines Logo
3:56 pm - 7:50 am
BUF
-
SCL
14h 54m
1 stop
LATAM Airlines Logo
11:00 pm - 11:01 am
SCL
-
BUF
36h 01m
2 stops
$921LATAM Airlines
Thu, Apr 2 - Fri, Apr 10
LATAM Airlines Logo
3:56 pm - 10:15 pm
BUF
-
SCL
29h 19m
3 stops
LATAM Airlines Logo
8:40 am - 3:14 pm
SCL
-
BUF
30h 34m
3 stops
$943LATAM Airlines
Thu, Apr 2 - Fri, Apr 10
LATAM Airlines Logo
3:56 pm - 7:50 am
BUF
-
SCL
14h 54m
1 stop
LATAM Airlines Logo
7:45 am - 11:21 am
SCL
-
BUF
27h 36m
2 stops
$976LATAM Airlines
Thu, Apr 2 - Sat, Apr 11
LATAM Airlines Logo
12:07 pm - 7:00 am
BUF
-
SCL
17h 53m
2 stops
LATAM Airlines Logo
11:05 pm - 11:01 am
SCL
-
BUF
35h 56m
2 stops
$1,024LATAM Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to Santiago flights

Get data-powered insights and trends into flights from Buffalo to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Buffalo to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Buffalo to Santiago were found on LATAM Airlines ($826) and Delta ($1,039).

Good to know

Cheapest flight$484
Flight from Buffalo to Santiago

When to book flights from Buffalo to Santiago

Are your dates flexible? Find out the best times to travel from Buffalo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Buffalo to Santiago

  • What is the cheapest flight from Buffalo to Santiago?

    In the last 3 days, the lowest price for a flight from Buffalo to Santiago was $484 for a one-way ticket and $826 for a round-trip.

  • Do I need a passport to fly between Buffalo and Santiago?

    Yes

  • Which aircraft models fly most regularly from Buffalo to Santiago?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Buffalo to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Buffalo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Buffalo with another airline. Booking your flights between Buffalo and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Buffalo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Buffalo to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1921 reviews
8.0Crew
7.0Entertainment
6.7Food
7.3Comfort
7.5Boarding
Airline reviews

Apart of Sky miles delta. And they go everywhere in Brazil

10.0 ExcellentAnonymous, Feb 2026
MCO - GRU
Read more LATAM Airlines reviews

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Everything you need to know for your flight from Buffalo to Santiago

Information on your arrival and departure airports