BUF - SCL

$316 Find Cheap Flights from Buffalo to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to Santiago departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Buffalo to Santiago, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Buffalo to Santiago (BUF-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to Santiago

Thu, Apr 2 - Sat, Apr 11
LATAM Airlines Logo
6:00 am - 2:30 pmBUF-SCL
31h 30m3 stops
LATAM Airlines Logo
11:05 pm - 10:35 amSCL-BUF
35h 30m2 stops
$849LATAM Airlines
Find Deal
Thu, Apr 2 - Sat, Apr 11
LATAM Airlines Logo
12:09 pm - 6:50 amBUF-SCL
17h 41m2 stops
LATAM Airlines Logo
11:05 pm - 10:35 amSCL-BUF
35h 30m2 stops
$899LATAM Airlines
Find Deal
Thu, Apr 2 - Sat, Apr 11
Delta Logo
6:50 pm - 8:00 amBUF-SCL
12h 10m1 stop
Delta Logo
8:40 pm - 11:57 pmSCL-BUF
27h 17m1 stop
$1,007Delta
Find Deal
Thu, Apr 2 - Sat, Apr 11
LATAM Airlines Logo
12:09 pm - 8:00 amBUF-SCL
18h 51m1 stop
LATAM Airlines Logo
8:40 pm - 11:57 pmSCL-BUF
27h 17m1 stop
$1,069LATAM Airlines
Find Deal
Fri, Dec 26 - Fri, Jan 9
Delta Logo
6:00 am - 7:40 amBUF-SCL
23h 40m1 stop
Delta Logo
6:30 pm - 2:58 pmSCL-BUF
22h 28m2 stops
$1,449Delta
Find Deal
Fri, Dec 26 - Fri, Jan 9
American Airlines Logo
6:24 am - 7:45 amBUF-SCL
23h 21m1 stop
American Airlines Logo
11:15 pm - 9:06 pmSCL-BUF
23h 51m1 stop
$1,839American Airlines
Find Deal
Thu, Apr 2 - Fri, Apr 10
Copa Airlines Logo
10:20 am - 6:00 amBUF-SCL
18h 40m2 stops
Copa Airlines Logo
12:46 am - 8:31 pmSCL-BUF
19h 45m2 stops
$2,022Copa Airlines
Find Deal
Thu, Apr 2 - Fri, Apr 10
Copa Airlines Logo
6:00 am - 6:00 amBUF-SCL
23h 00m2 stops
Copa Airlines Logo
12:46 am - 8:31 pmSCL-BUF
19h 45m2 stops
$2,125Copa Airlines
Find Deal
Sat, Feb 21 - Fri, Feb 27
Multiple Airlines Logo
9:15 am - 5:30 amBUF-SCL
18h 15m2 stops
Multiple Airlines Logo
1:35 am - 7:06 pmSCL-BUF
19h 31m2 stops
$4,495Multiple Airlines
Find Deal
Sat, Feb 21 - Sat, Feb 28
American Airlines Logo
5:00 am - 9:05 amBUF-SCL
26h 05m1 stop
American Airlines Logo
11:15 pm - 10:35 pmSCL-BUF
25h 20m1 stop
$7,582American Airlines
Find Deal

Everything you should know

Top airlines
LATAM Airlines
Cheapest • from $849 (round-trip)
LATAM Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$849
LATAM Airlines
Thu 4/2Sat 4/11
BUF - SCL • 3 stops
Cheapest one-way
$316
Multiple Airlines
Sat 11/15
BUF - SCL • 3 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Booking Insights

KAYAK's insights & trends for Buffalo to Santiago flights

Get data-powered insights and trends into flights from Buffalo to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Buffalo to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Buffalo to Santiago were found on LATAM Airlines ($849) and Delta ($1,007).

Which airlines fly non-stop between Buffalo and Santiago?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Buffalo to Santiago.

There is just one airline that flies from Buffalo to Santiago direct and that is LATAM Airlines. The best round-trip deal found from LATAM Airlines for the route is $763.

Find deals

Good to know

Cheapest flight$316
Flight from Buffalo to Santiago

When to book flights from Buffalo to Santiago

Are your dates flexible? Find out the best times to travel from Buffalo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Buffalo to Santiago

  • What is the cheapest flight from Buffalo to Santiago?

    In the last 3 days, the lowest price for a flight from Buffalo to Santiago was $316 for a one-way ticket and $849 for a round-trip.

  • Do I need a passport to fly between Buffalo and Santiago?

    Yes

  • Which aircraft models fly most regularly from Buffalo to Santiago?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Buffalo to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Buffalo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Buffalo with another airline. Booking your flights between Buffalo and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Buffalo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Buffalo to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Buffalo to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Buffalo to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1871 reviews
7.5Boarding
8.0Crew
6.7Food
7.3Comfort
7.0Entertainment
Airline reviews

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

2.0 MediocreBenjamin, Oct 2025MIA - LIM
Read more LATAM Airlines reviews

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Everything you need to know for your flight from Buffalo to Santiago

Information on your arrival and departure airports

Buffalo (BUF)
Santiago (SCL)

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.