$125 Find Cheap Flights from Buffalo to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to South America departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Buffalo to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$614
Bogotá
Bogotá2 stops$408
Santiago
Santiago2 stops$863
Cartagena
Cartagena1 stop$329
Quito
Quito2 stops$643
Barranquilla
Barranquilla2 stops$976
Lima
Lima2 stops$614
Bogotá
Bogotá2 stops$408
Santiago
Santiago2 stops$863
Cartagena
Cartagena1 stop$329
Quito
Quito2 stops$643
Barranquilla
Barranquilla2 stops$976

Book Cheap Buffalo to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to South America

Mon, Feb 23 - Wed, Feb 25
American Airlines Logo
7:41 pm - 2:06 pm
BUF
-
MDE
18h 25m
2 stops
American Airlines Logo
3:10 pm - 11:43 am
MDE
-
BUF
20h 33m
2 stops
$265American Airlines
Fri, Feb 20 - Wed, Feb 25
United Airlines Logo
7:21 pm - 10:05 pm
BUF
-
MDE
26h 44m
2 stops
United Airlines Logo
10:45 am - 8:51 pm
MDE
-
BUF
34h 06m
2 stops
$324United Airlines
Mon, Feb 23 - Fri, Mar 6
JetBlue Logo
6:00 am - 2:40 pm
BUF
-
CTG
8h 40m
1 stop
JetBlue Logo
2:35 pm - 11:38 pm
CTG
-
BUF
9h 03m
1 stop
$329JetBlue
Mon, Feb 23 - Fri, Mar 6
JetBlue Logo
6:00 am - 2:40 pm
BUF
-
CTG
8h 40m
1 stop
JetBlue Logo
2:35 pm - 11:38 pm
CTG
-
BUF
9h 03m
1 stop
$361JetBlue
Tue, Mar 10 - Thu, Mar 26
Delta Logo
6:00 am - 1:15 pm
BUF
-
CTG
8h 15m
1 stop
Delta Logo
2:30 pm - 11:46 pm
CTG
-
BUF
8h 16m
1 stop
$379Delta
Mon, Feb 23 - Fri, Mar 6
Multiple Airlines Logo
6:00 am - 2:40 pm
BUF
-
CTG
8h 40m
1 stop
Multiple Airlines Logo
3:32 pm - 11:09 am
CTG
-
BUF
19h 37m
2 stops
$405Multiple Airlines
Fri, Feb 27 - Mon, Mar 2
Multiple Airlines Logo
1:39 pm - 12:47 pm
BUF
-
BOG
23h 08m
2 stops
Multiple Airlines Logo
1:45 pm - 6:21 pm
BOG
-
BUF
28h 36m
1 stop
$408Multiple Airlines
Thu, Mar 12 - Thu, Mar 19
LATAM Airlines Logo
12:07 pm - 7:30 pm
BUF
-
BOG
8h 23m
1 stop
LATAM Airlines Logo
9:00 am - 11:46 pm
BOG
-
BUF
13h 46m
1 stop
$517LATAM Airlines
Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
6:00 am - 8:20 pm
BUF
-
LIM
15h 20m
2 stops
LATAM Airlines Logo
12:00 pm - 11:01 am
LIM
-
BUF
22h 01m
1 stop
$667LATAM Airlines
Fri, Mar 20 - Tue, Mar 31
Delta Logo
12:07 pm - 9:20 am
BUF
-
LIM
22h 13m
2 stops
Delta Logo
12:05 am - 5:37 pm
LIM
-
BUF
16h 32m
1 stop
$685Delta
Booking Insights

KAYAK's insights & trends for Buffalo to South America flights

Get data-powered insights and trends into flights from Buffalo to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Buffalo to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Buffalo to South America were found on American Airlines ($265) and United Airlines ($324).

Good to know

Low seasonOctober
Cheapest flight$127
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Buffalo to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Buffalo to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Buffalo to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Buffalo to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Buffalo to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Buffalo to South America

 
Need help choosing which airline to fly with from Buffalo to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8124 reviews
7.2Food
8.5Crew
7.9Comfort
8.1Boarding
7.8Entertainment
Airline reviews

The flight was comfortable and uneventful, which is what I desire

8.0 ExcellentLarry, Jan 2026
JFK - SJD
Read more Delta reviews

The flight was comfortable and uneventful, which is what I desire

The entertainment screens were not working and there was no air condition the entire flight. Very uncomfortable.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

I truly love flying with Delta. They have always treated me with the upmost respect

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Everything you need to know for your flight to South America

Information on your arrival and departure airports