$225 Find Cheap Flights from Buffalo to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to South America departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Buffalo to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$701
Bogotá
Bogotá1 stop$442
Santiago
Santiago1 stop$975
Cartagena
Cartagena2 stops$477
Quito
Quito2 stops$668
Barranquilla
Barranquilla2 stops$612
Lima
Lima2 stops$701
Bogotá
Bogotá1 stop$442
Santiago
Santiago1 stop$975
Cartagena
Cartagena2 stops$477
Quito
Quito2 stops$668
Barranquilla
Barranquilla2 stops$612

Book Cheap Buffalo to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to South America

Fri, Apr 24 - Fri, May 1
American Airlines Logo
7:28 pm - 12:48 pm
BUF
-
MDE
18h 20m
2 stops
American Airlines Logo
1:50 pm - 1:05 pm
MDE
-
BUF
22h 15m
2 stops
$392American Airlines
Wed, Apr 8 - Tue, Apr 14
Multiple Airlines Logo
7:44 pm - 11:55 am
BUF
-
BOG
17h 11m
1 stop
Multiple Airlines Logo
2:10 pm - 12:52 pm
BOG
-
BUF
21h 42m
2 stops
$442Multiple Airlines
Wed, Apr 8 - Thu, Apr 16
Multiple Airlines Logo
7:44 pm - 11:55 am
BUF
-
BOG
17h 11m
1 stop
Multiple Airlines Logo
2:07 pm - 11:13 am
BOG
-
BUF
20h 06m
2 stops
$445Multiple Airlines
Sun, Apr 12 - Sun, Apr 26
United Airlines Logo
6:09 am - 9:10 pm
BUF
-
MDE
16h 01m
2 stops
United Airlines Logo
9:45 am - 8:43 pm
MDE
-
BUF
33h 58m
2 stops
$486United Airlines
Mon, Apr 20 - Tue, Apr 28
GOL Logo
6:00 am - 8:15 pm
BUF
-
MDE
15h 15m
2 stops
GOL Logo
6:00 am - 9:36 pm
MDE
-
BUF
14h 36m
2 stops
$523GOL
Sat, May 2 - Thu, May 7
LATAM Airlines Logo
12:09 pm - 7:15 pm
BUF
-
BOG
8h 06m
1 stop
LATAM Airlines Logo
9:00 am - 6:45 pm
BOG
-
BUF
8h 45m
1 stop
$565LATAM Airlines
Fri, May 1 - Sun, May 3
LATAM Airlines Logo
7:40 pm - 11:00 pm
BUF
-
UIO
28h 20m
2 stops
LATAM Airlines Logo
6:50 pm - 3:53 pm
UIO
-
BUF
20h 03m
2 stops
$668LATAM Airlines
Fri, Apr 24 - Thu, Apr 30
Delta Logo
6:00 am - 6:59 pm
BUF
-
UIO
13h 59m
1 stop
Delta Logo
12:59 am - 3:39 pm
UIO
-
BUF
13h 40m
1 stop
$749Delta
Fri, Apr 24 - Thu, Apr 30
Delta Logo
3:33 pm - 4:43 am
BUF
-
UIO
14h 10m
2 stops
Delta Logo
12:59 am - 6:35 pm
UIO
-
BUF
16h 36m
1 stop
$754Delta
Sat, Sep 5 - Thu, Sep 17
United Airlines Logo
7:52 pm - 8:15 am
BUF
-
GIG
35h 23m
2 stops
United Airlines Logo
9:05 pm - 11:52 pm
GIG
-
BUF
27h 47m
2 stops
$1,216United Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to South America flights

Get data-powered insights and trends into flights from Buffalo to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Buffalo to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Buffalo to South America were found on American Airlines ($412) and Delta ($570).

Good to know

Low seasonJanuary
Cheapest flight$208
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Buffalo to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Buffalo to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Buffalo to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Buffalo to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Buffalo to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Buffalo to South America

 
Need help choosing which airline to fly with from Buffalo to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8292 reviews
7.8Entertainment
8.5Crew
8.1Boarding
7.9Comfort
7.2Food
Airline reviews

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

8.0 ExcellentMary, Mar 2026
LGA - MKE
Read more Delta reviews

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Delayed. Hot. Passenger next to me was so large I couldn’t move.

The flight went very well, but the flight attendants didn't serve and food or drinks other than 1st class due to rough air but to be honest it wasn't that bumpy and I felt that they could've at least offered water and coffee perhaps. Also serving 1st class only is a bad look. I've been in 1st class many times and I would've felt that if the turbulence was too rough for the main cabin, it would be too rough for 1st class too.

There was an unruly family behind us that made the short flight miserable!!! The cabin crew did nothing to contain it.

My seatback screen didn’t work so that sucked because that’s what I was going to do on the plane.

The whole experience was excellent. As it most often is with Delta

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Boarding and crew were fantastic, but I paid for a window seat with no window. Seat 11D on a CRJ-900 apparently does not have a window. Lesson learned.

It was good. The leg room was not great in Row 1.

Delta flights recently are always delayed AND at jfk tney get the gates further away (need To walk 20’ to get to them/all the way at the end of the terminal). Not sure whats happening but price doesnt match experience!

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

Everything you need to know for your flight to South America

Information on your arrival and departure airports