$124 Find Cheap Flights from Buffalo to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Buffalo to South America departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Buffalo to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$664
Bogotá
Bogotá2 stops$385
Santiago
Santiago2 stops$804
Cartagena
Cartagena1 stop$268
Quito
Quito1 stop$599
Montevideo
Montevideo2 stops$933
Barranquilla
Barranquilla2 stops$554
Lima
Lima1 stop$664
Bogotá
Bogotá2 stops$385
Santiago
Santiago2 stops$804
Cartagena
Cartagena1 stop$268
Quito
Quito1 stop$599
Montevideo
Montevideo2 stops$933
Barranquilla
Barranquilla2 stops$554

Book Cheap Buffalo to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Buffalo to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Buffalo to South America

Mon, Feb 2 - Thu, Feb 5
JetBlue Logo
6:00 am - 2:50 pm
BUF
-
CTG
8h 50m1 stop
JetBlue Logo
2:20 pm - 11:47 pm
CTG
-
BUF
9h 27m1 stop
$268JetBlue
Mon, Feb 23 - Wed, Feb 25
American Airlines Logo
4:25 pm - 2:06 pm
BUF
-
MDE
21h 41m2 stops
American Airlines Logo
3:10 pm - 10:59 am
MDE
-
BUF
19h 49m2 stops
$298American Airlines
Fri, Feb 20 - Wed, Feb 25
United Airlines Logo
5:24 pm - 10:05 pm
BUF
-
MDE
28h 41m2 stops
United Airlines Logo
10:45 am - 11:44 pm
MDE
-
BUF
12h 59m2 stops
$308United Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
1:39 pm - 12:50 pm
BUF
-
BOG
23h 11m2 stops
Multiple Airlines Logo
1:45 pm - 6:36 pm
BOG
-
BUF
28h 51m1 stop
$385Multiple Airlines
Fri, Jan 23 - Sat, Jan 31
Delta Logo
7:45 pm - 2:17 pm
BUF
-
CTG
18h 32m2 stops
Delta Logo
3:32 pm - 11:11 am
CTG
-
BUF
19h 39m2 stops
$387Delta
Sat, Jan 24 - Sat, Jan 31
Delta Logo
2:08 pm - 2:17 pm
BUF
-
CTG
24h 09m1 stop
Delta Logo
3:32 pm - 11:28 pm
CTG
-
BUF
7h 56m1 stop
$390Delta
Mon, Feb 2 - Thu, Feb 5
United Airlines Logo
8:30 am - 10:05 pm
BUF
-
MDE
37h 35m2 stops
United Airlines Logo
10:45 am - 8:29 pm
MDE
-
BUF
33h 44m2 stops
$404United Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
7:59 pm - 12:50 pm
BUF
-
BOG
16h 51m1 stop
Multiple Airlines Logo
1:45 pm - 6:36 pm
BOG
-
BUF
28h 51m1 stop
$442Multiple Airlines
Mon, Feb 2 - Thu, Feb 5
LATAM Airlines Logo
6:00 am - 12:22 am
BUF
-
BAQ
18h 22m2 stops
LATAM Airlines Logo
10:21 pm - 11:28 pm
BAQ
-
BUF
25h 07m2 stops
$570LATAM Airlines
Mon, Feb 2 - Thu, Feb 5
LATAM Airlines Logo
6:00 am - 9:20 pm
BUF
-
LIM
15h 20m1 stop
LATAM Airlines Logo
11:40 pm - 5:54 pm
LIM
-
BUF
18h 14m1 stop
$664LATAM Airlines
Booking Insights

KAYAK's insights & trends for Buffalo to South America flights

Get data-powered insights and trends into flights from Buffalo to South America to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Buffalo to South America?

The average price of all round-trip flights from Buffalo to South America clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South America on a Tuesday, as we generally find the cheapest rates on that day for this route. On the other hand, Thursday is the most expensive day to fly from Buffalo to South America. For your return ticket, we recommend flying on a Tuesday and avoiding Thursdays for the best deals.

Good to know

Low seasonOctober
Cheapest flight$124
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Buffalo to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Buffalo to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Buffalo to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Buffalo to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Buffalo to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Buffalo to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Buffalo to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Buffalo to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Buffalo to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $631 on average. Morning departures are around 5% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $661.

Reviews of the top airlines flying from Buffalo to South America

 
Need help choosing which airline to fly with from Buffalo to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8007 reviews
7.9Comfort
7.3Food
8.1Boarding
8.5Crew
7.9Entertainment
Airline reviews

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

6.0 GoodMary Heather, Nov 2025
LGA - MKE
Read more Delta reviews

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

I truly love flying with Delta. They have always treated me with the upmost respect

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight was great. The gate location was way to far away!!!

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

I believe that a four-hour trip should have a meal. Delta had none.

Was charged for my luggage despite having been on one ticket from an international flight. Too tired to argue after 15 hours on flight. Was charged for rechecking it at JFK airport. Not sure why those off Kenya Airways were required to do that.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Everything you need to know for your flight to South America

Information on your arrival and departure airports