$170 Find Cheap Flights from Central America to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to St. Louis departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$282
Typical prices: $652-$668
Multiple Airlines
Fri 1/16Wed 1/21
GUA - STL • 1 stop
Cheapest one-way
$170
Typical prices: $311-$332
Multiple Airlines
Sun 2/8
GUA - STL • 2 stops
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Flight Deals
Useful Info
Flight Deals

Cheap Flights from Central America to St. Louis

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Central America to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Central America to St. Louis

Fri, Jan 16 - Wed, Jan 21
Multiple Airlines Logo
2:46 pm - 6:51 am
GUA
-
STL
16h 05m1 stop
Multiple Airlines Logo
5:42 pm - 1:16 pm
STL
-
GUA
19h 34m2 stops
$282Multiple Airlines
Fri, Jan 16 - Wed, Jan 21
Multiple Airlines Logo
2:46 pm - 6:51 am
GUA
-
STL
16h 05m1 stop
Multiple Airlines Logo
5:42 pm - 11:20 am
STL
-
GUA
17h 38m1 stop
$312Multiple Airlines
Thu, Jan 29 - Mon, Feb 2
United Airlines Logo
8:45 am - 10:00 pm
SJO
-
STL
13h 15m1 stop
United Airlines Logo
6:00 am - 1:15 pm
STL
-
SJO
7h 15m1 stop
$357United Airlines
Thu, Jan 29 - Mon, Feb 2
United Airlines Logo
6:30 am - 12:29 pm
SJO
-
STL
29h 59m2 stops
United Airlines Logo
10:07 am - 6:16 pm
STL
-
SJO
8h 09m1 stop
$361United Airlines
Tue, Feb 24 - Sun, Mar 1
American Airlines Logo
3:55 pm - 10:26 am
SJO
-
STL
18h 31m1 stop
American Airlines Logo
6:15 pm - 12:23 pm
STL
-
SJO
18h 08m1 stop
$364American Airlines
Thu, Jan 29 - Mon, Feb 2
United Airlines Logo
8:45 am - 2:30 pm
SJO
-
STL
29h 45m2 stops
United Airlines Logo
6:00 am - 8:39 pm
STL
-
SJO
14h 39m1 stop
$367United Airlines
Tue, Feb 24 - Sun, Mar 1
American Airlines Logo
3:55 pm - 10:26 am
SJO
-
STL
18h 31m1 stop
American Airlines Logo
6:58 pm - 10:25 am
STL
-
SJO
15h 27m2 stops
$368American Airlines
Wed, Dec 24 - Tue, Mar 24
United Airlines Logo
8:45 am - 10:43 pm
SJO
-
STL
13h 58m2 stops
United Airlines Logo
11:25 am - 9:32 pm
STL
-
SJO
11h 07m2 stops
$377United Airlines
Fri, Dec 26 - Sat, Jan 3
Delta Logo
7:00 am - 4:28 pm
SJO
-
STL
9h 28m1 stop
Delta Logo
7:00 am - 9:55 pm
STL
-
SJO
14h 55m1 stop
$398Delta
Thu, Dec 25 - Mon, Jan 5
Delta Logo
1:28 pm - 11:38 pm
SAP
-
STL
10h 10m1 stop
Delta Logo
6:00 am - 12:30 pm
STL
-
SAP
6h 30m1 stop
$696Delta
Useful Info

Good to know

Low seasonJanuary
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 30% increase in price.

FAQs for booking flights from Central America to St. Louis

  • How does KAYAK find such low prices on flights from Central America to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Central America to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Central America to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Central America to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Central America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Central America to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Central America to St. Louis

 
Need help choosing which airline to fly with from Central America to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8009 reviews
7.9Entertainment
7.9Comfort
8.1Boarding
8.5Crew
7.3Food
Airline reviews

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

6.0 GoodJeff, Dec 2025
JFK - MIA
Read more Delta reviews

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

For some reason, I couldn't choose my seat. The airline gave me a seat when I got there. Not happy about that. Otherwise, everything else was great!

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

Staff on board was excellent. Positive upbeat helpful- like it used to be.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

For an expensive flight to another country, United has a lot of nerve serving pretzels and no meals (unless, of course, you want to buy something to eat). Unacceptable.

The food is terrible. The same pasta or chicken with bad taste and presentation

United have really come back. Airport and boarding process is clear and good, app and information also very good

The Sears in the 800s are not too good perfect Airbus why cant the new 737 fix that

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

It was probably one of the worst flights I’ve been on. The restrooms were never cleaned or stocked. The food was very subpar, and i usually enjoy airline food, so I was disappointed. It was just all around a bad experience. The only saving grace was the flight attendants.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very bad! They kept delaying my flight and wouldn’t do anything about it

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Wentzville
Farmington
Eureka
Litchfield
Grafton
Shrewsbury
Glencoe

Everything you need to know for your flight to St. Louis

Information on the airport you'll fly into in St. Louis