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Flight Deals
Cheap Flights from Charleston to Iowa
Cheapest round-trip prices found by our users on KAYAK in the last 5 daysBook Cheap Charleston to Iowa Plane Tickets
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Iowa that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Recent round-trip flight deals from Charleston to Iowa
Tue, Dec 8 - Thu, Dec 10
7:35 pm - 11:30 pmCHS Charleston-DSM Des Moines
4h 55m1 stop Charlotte Douglas
11:38 am - 7:43 pmDSM Des Moines-CHS Charleston
7h 05m1 stop Charlotte Douglas
$281American Airlines
Tue, Nov 17 - Tue, Nov 24
4:17 pm - 10:35 pmCHS Charleston-DSM Des Moines
7h 18m1 stop Atlanta Hartsfield-Jackson
5:30 am - 11:52 amDSM Des Moines-CHS Charleston
5h 22m1 stop Atlanta Hartsfield-Jackson
$281Delta
Mon, Jan 4 - Thu, Jan 14
3:33 pm - 10:36 pmCHS Charleston-DSM Des Moines
8h 03m1 stop Washington, D.C. Reagan-National
8:07 am - 1:29 pmDSM Des Moines-CHS Charleston
4h 22m1 stop Charlotte Douglas
$339American Airlines
Tue, Nov 17 - Tue, Nov 24
3:23 pm - 9:13 pmCHS Charleston-DSM Des Moines
6h 50m1 stop Minneapolis St Paul
5:30 am - 11:52 amDSM Des Moines-CHS Charleston
5h 22m1 stop Atlanta Hartsfield-Jackson
$339Delta
Tue, Dec 8 - Thu, Dec 10
8:00 am - 11:25 amCHS Charleston-DSM Des Moines
4h 25m1 stop Chicago Midway
6:00 am - 5:25 pmDSM Des Moines-CHS Charleston
10h 25m2 stops Chicago Midway Nashville Intl
$353Southwest
Tue, Dec 8 - Thu, Dec 10
6:35 am - 2:15 pmCHS Charleston-DSM Des Moines
8h 40m2 stops Nashville Intl Denver Intl
6:00 am - 5:25 pmDSM Des Moines-CHS Charleston
10h 25m2 stops Chicago Midway Nashville Intl
$358Southwest
Tue, Dec 8 - Thu, Dec 10
6:02 am - 1:35 pmCHS Charleston-DSM Des Moines
8h 33m2 stops Charlotte Douglas Chicago O'Hare Intl
5:24 am - 1:03 pmDSM Des Moines-CHS Charleston
6h 39m1 stop Washington, D.C. Reagan-National
$364American Airlines
Thu, Nov 12 - Mon, Nov 16
7:17 pm - 11:09 pmCHS Charleston-CID Cedar Rapids
4h 52m1 stop Atlanta Hartsfield-Jackson
5:15 am - 10:13 amCID Cedar Rapids-CHS Charleston
3h 58m1 stop Atlanta Hartsfield-Jackson
$369Delta
Thu, Nov 12 - Sun, Nov 15
7:13 am - 11:48 amCHS Charleston-CID Cedar Rapids
5h 35m1 stop Chicago O'Hare Intl
6:15 am - 1:38 pmCID Cedar Rapids-CHS Charleston
6h 23m1 stop Charlotte Douglas
$369American Airlines
Thu, Nov 12 - Sun, Nov 15
7:00 pm - 10:56 pmCHS Charleston-CID Cedar Rapids
4h 56m1 stop Chicago O'Hare Intl
6:00 am - 2:28 pmCID Cedar Rapids-CHS Charleston
7h 28m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$374United Airlines
Recent one-way flight deals from Charleston to Iowa
Fri, Nov 13
3:14 pm - 10:15 pmCHS Charleston-DSM Des Moines
8h 01m1 stop Fort Myers SW Florida Intl
$127Multiple Airlines
Thu, Jan 7
10:15 pm - 10:25 amCHS Charleston-CID Cedar Rapids
13h 10m1 stop Fort Lauderdale
$130Multiple Airlines
Wed, Nov 18
6:10 am - 10:21 amCHS Charleston-DSM Des Moines
5h 11m1 stop Charlotte Douglas
$141American Airlines
Sat, Nov 21
3:29 pm - 9:55 pmCHS Charleston-DSM Des Moines
7h 26m1 stop Chicago O'Hare Intl
$141United Airlines
Wed, Nov 18
8:30 am - 4:07 pmCHS Charleston-DSM Des Moines
8h 37m2 stops Chicago O'Hare Intl Denver Intl
$146United Airlines
Thu, Nov 26
9:00 am - 12:53 pmCHS Charleston-CID Cedar Rapids
4h 53m1 stop Charlotte Douglas
$170American Airlines
Tue, Jan 5
1:05 pm - 5:19 pmCHS Charleston-DSM Des Moines
5h 14m1 stop Detroit Metropolitan Wayne County
$170Delta
Wed, Nov 25
8:29 pm - 11:58 pmCHS Charleston-CID Cedar Rapids
4h 29m1 stop Charlotte Douglas
$170American Airlines
Fri, Nov 27
7:05 am - 10:44 amCHS Charleston-DSM Des Moines
4h 39m1 stop Atlanta Hartsfield-Jackson
$190Delta
Thu, Nov 12
5:34 pm - 10:35 pmCHS Charleston-DSM Des Moines
6h 01m1 stop Atlanta Hartsfield-Jackson
$269Delta
Recent last minute flight deals from Charleston to Iowa
Sun, Nov 1 - Sat, Nov 7
7:00 am - 9:34 amCHS Charleston-DSM Des Moines
27h 34m2 stops Cincinnati Cinci./N. Kentucky Tampa
9:00 am - 8:38 amDSM Des Moines-CHS Charleston
22h 38m1 stop Orlando Sanford Intl
$634Multiple Airlines
Sun, Nov 1 - Sat, Nov 7
9:39 pm - 9:34 amCHS Charleston-DSM Des Moines
12h 55m1 stop Tampa
9:00 am - 8:38 amDSM Des Moines-CHS Charleston
22h 38m1 stop Orlando Sanford Intl
$682Multiple Airlines
Sun, Nov 1 - Sat, Nov 7
7:00 am - 5:28 pmCHS Charleston-DSM Des Moines
11h 28m2 stops Newark Chicago O'Hare Intl
11:23 am - 11:59 pmDSM Des Moines-CHS Charleston
11h 36m2 stops Chicago O'Hare Intl Newark
$837United Airlines
Booking Insights
KAYAK's insights & trends for Charleston to Iowa flights
Get data-powered insights and trends into flights from Charleston to Iowa to help you find the cheapest flights, the best time to fly and much more.
Prices
Airlines
More
Good to know
Low season | February |
|---|---|
High season | June |
Cheapest flight | $127 |
FAQs - booking Iowa flights
Reviews of the top airlines flying from Charleston to Iowa
See real verified KAYAK customer reviews for airlines flying from Charleston to Iowa. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
7.8
DeltaOverall score based on 8692 reviews
7.8Entertainment
8.5Crew
7.8Comfort
7.2Food
8.1Boarding
Airline reviews
This flight was the flight we missed due to deltas delay at our first airport going TO Atlanta.
2.0 MediocreEmily, Oct 2026
This flight was the flight we missed due to deltas delay at our first airport going TO Atlanta.
Be on time. No issues with weather etc. entirely on airline.
Two of the flight attendants were cranky and seemed like they didn’t want to be there. Not up to normal Delta standards. And our bags didn’t make flight to Italy from Amsterdam resulting in having to make a trip back to airport which cost me 75 euros.
Delta staff was exceptionally helpful and considerate. However, the first two of three flight legs were delayed making connections tentative and stressful.
This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.
I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.
They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.
The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.
The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.
The plane was frigid, and leaked water from the ceiling all over me and my seat.
The first flight was delayed by an hour and a half, so we missed the second flight. They rebooked us on the later flight and I have to sit in the middle for more than 5 hours. Terrible experience. No more American Airlines.
Flight was fine, but not having WiFi was a major negative
I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization
The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.
Would have thought that they would gas up plane before everyone got on board
The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines
American switched my flight to a 5 hour layover then cancelled my whole reservation with no notice and refused refund. Won’t fly with them again.
We sat on runway for an 1 hour because they were short handed at key west airport was not fun
The WiFi and app don’t work as easily as other airlines
Late. Then next flight was an hour late due to mx.
More options for your flight from Charleston to Iowa
Complete your trip to Iowa with a hotel stay or car rental
Information on your arrival and departure airports
Cabin class types available on flights to Iowa
Cabin classes available on flights to Iowa. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from other airports in Charleston to Iowa
Flights from all airports in Charleston to Iowa. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from Charleston to popular cities in Iowa
Flights from Charleston to Dubuquefrom $643
Flights from Charleston to La Crossefrom $605
Flights from Charleston to Molinefrom $369
Flights from Charleston to Omahafrom $315