$127 Find Cheap Flights from South Carolina to Iowa - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheap Flights from South Carolina to Iowa

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Sort by: Cheapest
Omaha
2h 33mNonstop
from $250per person
Des Moines
2h 21mNonstop
from $256per person
La Crosse
4h 48m3 stops
from $280per person
Cedar Rapids
2h 14mNonstop
from $291per person
Sioux City
5h 54m2 stops
from $314per person
Moline
2h 19mNonstop
from $315per person
Waterloo
6h 23m3 stops
from $545per person
Useful Info

Good to know

Low season

January

Cheapest flight

$127
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Charleston to Omaha

FAQs for booking flights from South Carolina to Iowa

  • How does KAYAK find such low prices on flights from South Carolina to Iowa?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Iowa.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Iowa?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from South Carolina to Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Iowa?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from South Carolina to Iowa with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Iowa?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from South Carolina to Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in Iowa?

    There are 6 airports in Iowa. The busiest airport is Des Moines Airport (DSM), with 64% of all flights arriving there.

  • What is the cheapest month to fly from South Carolina to Iowa?

    The cheapest month for flights from South Carolina to Iowa is February, when tickets cost $158 (return) on average. On the other hand, the most expensive months are January and April, when the average cost of round-trip tickets is $368 and $338 respectively.

  • How long is the flight to Iowa?

    An average nonstop flight from South Carolina to Iowa takes 8h 27m, covering a distance of 865 miles. The shortest route is Charlotte (CLT) to Cedar Rapids (CID) with an average flight time of 2h 14m.

  • What are the most popular destinations in Iowa?

    Based on KAYAK flight searches, the most popular destination is Omaha (37% of total searches to Iowa). The next most popular destinations are Des Moines (34%) and Cedar Rapids (16%). Searches for flights to Moline (10%) and to La Crosse (3%) are also popular.

Reviews of the top 3 airlines serving from South Carolina to Iowa

 
Need help choosing which airline to fly with from South Carolina to Iowa? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8564 reviews
7.2Food
8.1Boarding
7.8Entertainment
8.5Crew
7.8Comfort
Airline reviews

Flight was delayed at airport with large backlog and WiFi was spotty

6.0 GoodAnn, Sep 2026
Read more Delta reviews

Flight was delayed at airport with large backlog and WiFi was spotty

I don’t like mushrooms and that’s all they had with pasta

Delta staff was exceptionally helpful and considerate. However, the first two of three flight legs were delayed making connections tentative and stressful.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.

The plane was frigid, and leaked water from the ceiling all over me and my seat.

Even through the flight was delayed due to storms near IAH The flight was great! The crew was so hospitable and professional

A long delay. Don't travel late in the day.

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

United Airlines is my preferred airlines and I am thankful for Gary who also help support me on the phone to switch my flight literally last min.

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

It was great, I’m very grateful for the pilots and crew flight attendants for everything.

The attendant were friendly. I suggest you have a medical attendant on board every flight so that in case someone is sick , he/she will help them.

Flight was great. Efficient boarding. Short flight. Early arrival. Friendly flight crew. The entertainment system did not work well. Could not access it until the aircraft reached 10K feet or more. Lots of glitches.

No food service almost missed because of first flight delays

The flight and boarding were easy peasy. I was traveling with my 4-year-old, so a smooth boarding experience was especially appreciated. My only piece of feedback is really about where our gate was in O'Hare. They've shoved four gates into a tiny corner of the B terminal and there isn't early enough room or seating for everyone. Not United's problem, but did dent the overall experience.

I paid extra for a seat up front and at last minute was moved to the 2nd to last row - which I could have had for free. No reason and no refund. Really great customer service American

The first flight was delayed by an hour and a half, so we missed the second flight. They rebooked us on the later flight and I have to sit in the middle for more than 5 hours. Terrible experience. No more American Airlines.

Very good I can’t complain one bit. Thank you American Airlines for making my flight enjoyable and safe!

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

I blame kayak for my last trip to dca. Kayak cancelled my direct flight and put on a one stop flight and made lost whole day from my vacation and had not even refunded my ticket.

delayed multiple times. no resolution on anything from AA customer service. was put on hold in chat to talk to manager. was 6th in line to talk to manager for more than TWELVE HOURS - from sometime around 9AM until well after I had gone to bed that evening. no explanation, no attempt to make it right. just a five hour delay because of repeated maintenance claims

Was the most uncomfortable I ever had in the air. Felt like I was trapped in the seat legs cramped and was just horrible. The flight to DSM was a lot better. Even being on a smaller plane was better. Staff are outstanding. No complaints about the people.

It was exactly as I expected, on time, smooth flight, courteous staff.

More options for your flight to Iowa

Complete your trip to Iowa with a hotel stay or car rental