$72 Find Cheap Flights from South Carolina to Iowa

1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Iowa

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 20% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Useful Info

Good to know

Low seasonFebruary
High seasonJuly
Cheapest flight$72
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly and prices are also 0% lower on average.
Flight from Charlotte to Des Moines

FAQs for booking flights from South Carolina to Iowa

  • How does KAYAK find such low prices on flights from South Carolina to Iowa?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Iowa.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Iowa?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from South Carolina to Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Iowa?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from South Carolina to Iowa with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Iowa?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from South Carolina to Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Iowa?

    Based on KAYAK data, the cheapest day to fly to Iowa is Wednesday where round-trip tickets can be as cheap as $321. On the other hand, the most expensive day to fly is Saturday, where round-trip prices are $594 on average.

  • What is the cheapest time of day to fly to Iowa?

    The cheapest time of day to fly to Iowa is generally in the evening, when round-trip flights cost $411 on average. Morning departures are around 8% more expensive than evening flights, on average. The most expensive time of day to fly to Iowa is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $485.

  • What is the cheapest month to fly from South Carolina to Iowa?

    The cheapest month for flights from South Carolina to Iowa is July, when tickets cost $278 (return) on average. On the other hand, the most expensive months are April and May, when the average cost of round-trip tickets is $933 and $529 respectively.

  • How long is the flight to Iowa?

    An average nonstop flight from South Carolina to Iowa takes 6h 43m, covering a distance of 865 miles. The shortest route is Charlotte (CLT) to Moline (MLI) with an average flight time of 2h 07m.

  • What are the most popular destinations in Iowa?

    Based on KAYAK flight searches, the most popular destination is Omaha (41% of total searches to Iowa). The next most popular destinations are Des Moines (32%) and Cedar Rapids (15%). Searches for flights to Moline (10%), to Dubuque (2%) and to La Crosse (1%) are also popular.

Top airlines flying from South Carolina to Iowa

 
Need help choosing which airline to fly with from South Carolina to Iowa? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7963 reviews
8.2Boarding
8.5Crew
7.3Food
7.9Comfort
7.9Entertainment
Airline reviews

The flight was scheduled for 2:30 PM. Early in the morning we got a text message saying the flight was delayed and rescheduled for 3:00 PM. We got to the airport with that in mind. Then we got a message during check-in at the flight was rescheduled again for 2:30 PM. We almost missed our flight. In fact, our bags Were told that they would not make it. At the end, everything worked out. But it is very stressful.

4.0 OkayKoonj, Jun 2025MSP - AUS
Read more Delta reviews

The flight was scheduled for 2:30 PM. Early in the morning we got a text message saying the flight was delayed and rescheduled for 3:00 PM. We got to the airport with that in mind. Then we got a message during check-in at the flight was rescheduled again for 2:30 PM. We almost missed our flight. In fact, our bags Were told that they would not make it. At the end, everything worked out. But it is very stressful.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Great overall. There was a bit of turbulence so they could only serve water because too much turbulence for the carts. Was glad they prioritized safety though

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

Great service. Flight was delayed while we sat on the runway for a couple of hours. Weather related. Staff made is very bearable. The steward servicing the first class cabin was exceptional. Thank you! 💗

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

My flight was 6 pm 6/6. Every hour they delayed it again - air condition issues then no pilot then the crew had worked too many hours and cancelled the flight at 11 pm. Sent customers to NJ a 45 minutes uber ride to a hotel. Had to be back by 5 am for a 7 am flight and again no pilot etc with another three hours of delays.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

I’m impressed that we were on time in Sacramento after having a late departure in Newark and our made it. The staff was friendly and warm.

Cramped seats. FAA should make airlines have more legroom, for even short people complain

5.5 hour delay with no explanation on why, along with no proactive effort to reaccomodate me.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

Most miserable flight ever. We waited almost 2 hours on the runway because the flight was oversold. American offered $1200 credit. Then there was some nonsense about weight distribution. Ridiculous. No food for 8 plus hours on the flight. I will be writing a letter.

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

The plane was probably full boarding was easy. We were able to check our carry-on luggage for free. It was a return flight through Philly to LA. Never saw a stewardess do a demonstration of emergency Procedures. I think my flight was pretty full

Plane, flight, crew, captain were all great. The first flight had a Chipotle box lunch...delicious.

Book cheap flights from South Carolina to Iowa

Recent round-trip flight deals

8/21Thu
1 stopSouthwest
6h 50mCLT-OMA
8/25Mon
1 stopSouthwest
4h 30mOMA-CLT
$144
8/21Thu
1 stopSouthwest
4h 40mCLT-OMA
8/25Mon
2 stopsSouthwest
10h 05mOMA-CLT
$150
8/7Thu
2 stops
17h 18mCLT-DSM
8/10Sun
1 stop
18h 30mDSM-CLT
$207
8/7Thu
1 stop
28h 05mCLT-DSM
8/10Sun
1 stop
18h 30mDSM-CLT
$216
9/18Thu
1 stopAmerican Airlines
4h 10mGSP-DSM
9/21Sun
1 stopAmerican Airlines
4h 56mDSM-GSP
$234
7/17Thu
1 stopAmerican Airlines
6h 44mCHS-CID
7/21Mon
1 stopAmerican Airlines
5h 24mCID-CHS
$249
8/21Thu
1 stopDelta
5h 58mCAE-DSM
8/23Sat
2 stopsDelta
10h 04mDSM-CAE
$289
7/1Tue
1 stopDelta
5h 14mGSP-OMA
7/5Sat
1 stopDelta
6h 58mOMA-GSP
$297
6/30Mon
1 stopUnited Airlines
6h 04mGSP-DSM
7/4Fri
1 stopUnited Airlines
4h 40mDSM-GSP
$297
6/30Mon
1 stopUnited Airlines
5h 12mGSP-DSM
7/4Fri
2 stopsUnited Airlines
11h 33mDSM-GSP
$302

Search by stops

Search by airline

Search by price

Recent one-way flight deals

8/25Mon
1 stopSouthwest
4h 00mCLT-DSM
$72
8/25Mon
2 stopsSouthwest
10h 40mCLT-DSM
$78
7/14Mon
1 stop
9h 42mCLT-DSM
$95
7/14Mon
1 stop
9h 42mCLT-DSM
$96
7/11Fri
1 stop
9h 42mCLT-DSM
$108
6/21Sat
1 stopFrontier
16h 23mCLT-OMA
$111
8/31Sun
1 stopAmerican Airlines
6h 06mGSP-DSM
$126
7/8Tue
1 stopAmerican Airlines
6h 26mCHS-OMA
$177
7/4Fri
1 stopDelta
6h 27mCAE-DSM
$210
7/4Fri
2 stopsDelta
10h 34mCAE-DSM
$215

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Iowa

Last minute flight, train and bus deals

6/21Sat
multi-stopDelta
4h 38mCHS-CID
6/24Tue
multi-stopDelta
7h 00mCID-CHS
$309
6/20Fri
multi-stop
22h 20mCLT-DSM
6/22Sun
multi-stop
23h 29mDSM-CLT
$354
6/20Fri
multi-stop
22h 20mCLT-DSM
6/22Sun
multi-stop
23h 29mDSM-CLT
$357
6/21Sat
nonstopAmerican Airlines
2h 09mCLT-MLI
6/25Wed
nonstopAmerican Airlines
2h 14mMLI-CLT
$413
6/21Sat
multi-stopAmerican Airlines
4h 27mCHS-CID
6/24Tue
multi-stopAmerican Airlines
7h 49mCID-CHS
$420
6/21Sat
multi-stopDelta
5h 48mCLT-MLI
6/25Wed
multi-stopDelta
7h 05mMLI-CLT
$433
6/20Fri
multi-stopAllegiant Air
29h 16mMYR-OMA
7/1Tue
multi-stopAllegiant Air
30h 53mOMA-MYR
$455
6/21Sat
multi-stopSouthwest
4h 45mCLT-OMA
6/24Tue
multi-stopSouthwest
5h 20mOMA-CLT
$470
6/21Sat
multi-stopSouthwest
7h 30mCLT-OMA
6/24Tue
multi-stopSouthwest
5h 20mOMA-CLT
$496
6/19Thu
multi-stopAllegiant Air
24h 44mMYR-OMA
6/21Sat
multi-stopAllegiant Air
20h 05mOMA-MYR
$544

Search by stops

Search by airline

Search by price

Everything you need to know for your flight to Iowa

Cabin class types available on flights to South Carolina

Cabin classes available on flights to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.