CHS - DSM

$152 Find Cheap Flights from Charleston to Des Moines - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$298
Typical prices: $335-$537
Multiple Airlines
Mon 10/1Thu 10/4
CHS - DSM • 1 stop
Cheapest one-way
$152
Typical prices: $169-$279
Multiple Airlines
Sat 9/29
CHS - DSM • 3 stops
Nonstop flights
Not available
There are currently no direct flights between Charleston and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
April
Cheapest • 24% price drop
October
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Charlotte Douglas (CLT)
Cheapest • Avg $344 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 4h 39m (one-way)
Insights
Insights
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We hope you love your trip to Des Moines!
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Booking Insights
Flight Deals

Cheap Flights from Charleston to Des Moines (CHS-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Des Moines

Thu, Oct 1 - Sun, Oct 4
Multiple Airlines Logo
2:13 pm - 8:35 amCHS  Charleston-DSM Des Moines
19h 22m1 stop Orlando
Multiple Airlines Logo
6:40 am - 1:50 pmDSM  Des Moines-CHS Charleston
30h 10m2 stops Philadelphia Tampa
$298Multiple Airlines
Sat, Oct 10 - Sat, Oct 17
Delta Logo
12:09 pm - 3:16 pmCHS  Charleston-DSM Des Moines
4h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:07 pm - 11:59 pmDSM  Des Moines-CHS Charleston
6h 52m1 stop Atlanta Hartsfield-Jackson
$325Delta
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
7:46 pm - 12:04 amCHS  Charleston-DSM Des Moines
5h 18m1 stop Chicago O'Hare Intl
American Airlines Logo
4:14 pm - 10:48 pmDSM  Des Moines-CHS Charleston
5h 34m1 stop Dallas/Fort Worth
$325American Airlines
Sat, Sep 26 - Sat, Oct 3
United Airlines Logo
5:05 pm - 10:16 pmCHS  Charleston-DSM Des Moines
6h 11m1 stop Houston George Bush Intcntl
United Airlines Logo
3:11 pm - 12:15 amDSM  Des Moines-CHS Charleston
8h 04m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$330United Airlines
Fri, Sep 18 - Sun, Sep 20
Multiple Airlines Logo
3:59 pm - 10:08 pmCHS  Charleston-DSM Des Moines
7h 09m1 stop Fort Myers SW Florida Intl
Multiple Airlines Logo
1:58 pm - 8:38 amDSM  Des Moines-CHS Charleston
41h 40m2 stops Philadelphia Orlando
$331Multiple Airlines
Sat, Sep 26 - Sat, Oct 3
Southwest Logo
6:45 am - 11:30 amCHS  Charleston-DSM Des Moines
5h 45m2 stops Lambert-St Louis Chicago Midway
Southwest Logo
5:50 am - 6:40 pmDSM  Des Moines-CHS Charleston
11h 50m2 stops Chicago Midway Nashville Intl
$341Southwest
Thu, Oct 1 - Sun, Oct 4
American Airlines Logo
7:18 am - 1:59 pmCHS  Charleston-DSM Des Moines
7h 41m1 stop Chicago O'Hare Intl
American Airlines Logo
7:05 am - 1:16 pmDSM  Des Moines-CHS Charleston
5h 11m1 stop Chicago O'Hare Intl
$371American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
8:08 pm - 11:58 pmCHS  Charleston-DSM Des Moines
4h 50m1 stop Charlotte Douglas
American Airlines Logo
1:15 pm - 10:00 pmDSM  Des Moines-CHS Charleston
7h 45m2 stops Philadelphia Charlotte Douglas
$376American Airlines
Sat, Oct 10 - Sat, Oct 17
Delta Logo
12:09 pm - 3:16 pmCHS  Charleston-DSM Des Moines
4h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:07 pm - 11:59 pmDSM  Des Moines-CHS Charleston
6h 52m1 stop Atlanta Hartsfield-Jackson
$391Delta
Tue, Oct 13 - Thu, Oct 15
Delta Logo
7:10 pm - 10:33 pmCHS  Charleston-DSM Des Moines
4h 23m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:54 pm - 11:59 pmDSM  Des Moines-CHS Charleston
4h 05m1 stop Atlanta Hartsfield-Jackson
$391Delta
Booking Insights

Price, demand and travel trends for Charleston to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Charleston to Des Moines with more confidence.

What's the cheapest day of the week to fly from Charleston to Des Moines?

Wednesday is the cheapest day of the week to fly from Charleston to Des Moines, it is 41% cheaper than the average day. Saturday is the most expensive day with flight prices 47% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Charleston to Des Moines?

  • April is the cheapest month to fly from Charleston to Des Moines at $316 round-trip.
  • August ($626) and June ($618) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 98% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Charleston to Des Moines flights

Low season

March

Cheapest flight

$152
Best time to beat the crowds with an average 22% drop in price.
Flight from Charleston to Des Moines

When to book flights from Charleston to Des Moines

Are your dates flexible? Find out the best times to travel from Charleston to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Charleston to Des Moines flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Charleston to Des Moines?

    Flights from Charleston to Des Moines usually depart from Charleston (CHS) and arrive at Des Moines (DSM).

  • What cabin classes can I book on flights from Charleston to Des Moines?

    Only Economy Class is available on flights from Charleston to Des Moines.

  • Which airports do connecting flights from Charleston to Des Moines pass through?

    One-stop flights from Charleston to Des Moines most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 59% of one-stop connections
    • Charlotte Douglas (CLT) - 32% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 3% of one-stop connections
    • Chicago Midway (MDW) - 3% of one-stop connections

    Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Charleston to Des Moines?

    Yes. Being flexible with your travel dates can save you up to 60% on the Charleston to Des Moines route. Wednesday is the cheapest departure day at $250 round-trip on average, while Saturday is the most expensive at $618, a difference of $368. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are Iowa Events Center, UnityPoint Health - Des Moines and Des Moines Civic Center. These are among the most viewed places in Des Moines on KAYAK.

  • How long is a flight from Charleston to Des Moines?

    A nonstop flight from Charleston to Des Moines takes 0h 00m, covering 956 miles.

  • Do I need a passport to fly from Charleston to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Charleston to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $298 to $1,843. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Charleston to Des Moines looking right now?

    One-way fares from Charleston to Des Moines are currently lower than usual. Average one-way flight prices are about $203, which is 5% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Charleston to Des Moines?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 4h 39m, compared with 4h 47m via Charlotte Douglas (CLT) and 4h 55m via Chicago Midway (MDW).

  • What is the time difference between Charleston and Des Moines?

    Des Moines is 1 hour behind Charleston (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    · Hertz
    · Payless
    · Budget
    · Alamo
    · Avis

  • How much should I expect to pay for a Charleston to Des Moines flight?

    Round-trip flights from Charleston to Des Moines range from $335 to $537, with an average of $418 over the past 12 months. Anything below $335 counts as a good deal.

Your guide to booking Charleston to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Saturday. On this route, Wednesday flights average $250 - about $368 less than Saturday (60% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Charleston to Des Moines trip for April. Fares historically average $316 round-trip in that month - typically $310 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.
    - Days Inn & Suites by Wyndham Des Moines Airport
    - Holiday Inn Des Moines-Airport/Conf Center By IHG
    - Quality Inn & Suites Des Moines Airport

Everything you need to know for your flight from Charleston to Des Moines

Information on your arrival and departure airports

Charleston (CHS)
Des Moines (DSM)