CHS - DSM

$136 Find Cheap Flights from Charleston to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Des Moines departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Des Moines, as well as popular online travel agencies
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Cheap Flights from Charleston to Des Moines

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Charleston to Des Moines

KAYAK's recommended round-trip deals from the most popular airlines that fly from Charleston to Des Moines.
Discover the best prices for you by selecting your travel dates on KAYAK.
American Airlines Logo
11:43 am - 5:43 pmCHS-DSM
7h 00m1 stop
American Airlines Logo
3:40 pm - 9:57 pmDSM-CHS
5h 17m1 stop
$324American Airlines
Find Deal
Thu, May 29 - Thu, Jun 5
American Airlines Logo
5:07 am - 12:21 pmCHS-DSM
8h 14m2 stops
American Airlines Logo
3:40 pm - 9:57 pmDSM-CHS
5h 17m1 stop
$329American Airlines
Find Deal
Thu, May 29 - Thu, Jun 5
American Airlines Logo
7:04 pm - 12:06 amCHS-DSM
6h 02m1 stop
American Airlines Logo
5:32 pm - 11:48 pmDSM-CHS
5h 16m1 stop
$335American Airlines
Find Deal
Thu, Jun 12 - Sun, Jun 15
American Airlines Logo
6:34 pm - 10:59 pmCHS-DSM
5h 25m1 stop
American Airlines Logo
5:00 am - 12:54 pmDSM-CHS
6h 54m2 stops
$340American Airlines
Find Deal
Thu, Jun 12 - Sun, Jun 15
Delta Logo
5:15 am - 2:03 pmCHS-DSM
9h 48m2 stops
Delta Logo
6:07 am - 6:54 pmDSM-CHS
11h 47m2 stops
$355Delta
Find Deal
Thu, Jun 12 - Sun, Jun 15
American Airlines Logo
6:34 pm - 10:59 pmCHS-DSM
5h 25m1 stop
American Airlines Logo
5:00 am - 11:57 amDSM-CHS
5h 57m1 stop
$359American Airlines
Find Deal
Fri, Jun 27 - Sun, Jul 6
American Airlines Logo
7:18 pm - 12:06 amCHS-DSM
5h 48m1 stop
American Airlines Logo
5:00 am - 12:56 pmDSM-CHS
6h 56m2 stops
$364American Airlines
Find Deal
Fri, Jun 27 - Sun, Jul 6
American Airlines Logo
6:34 pm - 11:52 pmCHS-DSM
6h 18m2 stops
American Airlines Logo
5:00 am - 12:56 pmDSM-CHS
6h 56m2 stops
$369American Airlines
Find Deal
Fri, Jun 27 - Sun, Jul 6
Delta Logo
5:15 am - 2:03 pmCHS-DSM
9h 48m2 stops
Delta Logo
6:07 am - 3:56 pmDSM-CHS
8h 49m2 stops
$387Delta
Find Deal
Thu, Jun 26 - Sun, Jun 29
Delta Logo
2:38 pm - 8:46 pmCHS-DSM
7h 08m2 stops
Delta Logo
1:07 pm - 11:44 pmDSM-CHS
9h 37m2 stops
$389Delta
Find Deal
Thu, May 29 - Thu, Jun 5
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KAYAK's insights & trends for Charleston to Des Moines flights

Get data-powered insights and trends into flights from Charleston to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Charleston to Des Moines?

The average price of all round-trip flights from Charleston to Des Moines clicked on KAYAK for each day over the last 12 months.

When flying from Charleston to Des Moines, you should consider leaving on a Wednesday and avoid Saturdays if you are looking for the best rates. For your return to Charleston, you’ll find the best rates on Mondays and the most expensive ones on Thursdays.

Good to know

Low seasonMay
High seasonAugust
Cheapest flight$136
Best time to beat the crowds with an average 37% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Charleston to Des Moines

When to book flights from Charleston to Des Moines

Are your dates flexible? Find out the best times to travel from Charleston to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Des Moines

  • What is the cheapest flight from Charleston to Des Moines?

    In the last 3 days, the lowest price for a flight from Charleston to Des Moines was $136 for a one-way ticket and $324 for a round-trip.

  • Do I need a passport to fly between Charleston and Des Moines?

    A passport is not required to fly from Charleston to Des Moines.

  • Which aircraft models fly most regularly from Charleston to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Des Moines?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Charleston and Des Moines, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Charleston to Des Moines, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Charleston to Des Moines are Delta and American Airlines. With an average price for the route of $449 and an overall rating of 8.0, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $449 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Charleston to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Charleston with another airline. Booking your flights between Charleston and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airlines flying from Charleston to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7936 reviews
7.3Food
7.9Comfort
8.5Crew
7.9Entertainment
8.2Boarding
Airline reviews

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

8.0 ExcellentFredrick, Apr 2025GSO - DTW
Read more Delta reviews

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Took off on time and successfully avoided weather that looked to be a problem along the way

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Everything you need to know for your flight from Charleston to Des Moines

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