CHS - DSM

$150 Find Cheap Flights from Charleston to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Des Moines departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$335
Typical prices: $595-$330
Southwest
Wed 6/17Wed 6/24
CHS - DSM • 1 stop
Cheapest one-way
$150
Typical prices: $202-$270
Multiple Airlines
Fri 6/19
CHS - DSM • 1 stop
Top airlines
Southwest
Cheapest • from $335 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Charleston and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Charlotte (CLT)
Cheapest • Avg $329 (round-trip)
Atlanta (ATL)
Shortest trip • 4h 33m (one-way)
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 20% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charleston to Des Moines (CHS-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Des Moines

Wed, Jun 17 - Wed, Jun 24
Southwest Logo
6:10 am - 11:30 am
CHS
-
DSM
6h 20m
1 stop
Southwest Logo
3:45 pm - 9:25 pm
DSM
-
CHS
4h 40m
1 stop
$335Southwest
Wed, Jun 17 - Wed, Jun 24
Southwest Logo
6:10 am - 11:30 am
CHS
-
DSM
6h 20m
1 stop
Southwest Logo
5:20 am - 6:15 pm
DSM
-
CHS
11h 55m
2 stops
$340Southwest
Tue, Jun 23 - Thu, Jun 25
American Airlines Logo
3:44 pm - 10:52 pm
CHS
-
DSM
8h 08m
1 stop
American Airlines Logo
1:51 pm - 10:49 pm
DSM
-
CHS
7h 58m
1 stop
$371American Airlines
Mon, Aug 17 - Thu, Aug 20
American Airlines Logo
7:43 pm - 11:44 pm
CHS
-
DSM
5h 01m
1 stop
American Airlines Logo
6:11 pm - 11:59 pm
DSM
-
CHS
4h 48m
1 stop
$375American Airlines
Tue, Jun 23 - Thu, Jun 25
American Airlines Logo
6:51 am - 1:21 pm
CHS
-
DSM
7h 30m
2 stops
American Airlines Logo
7:10 am - 5:39 pm
DSM
-
CHS
9h 29m
1 stop
$376American Airlines
Mon, Aug 17 - Thu, Aug 20
Southwest Logo
1:15 pm - 10:10 pm
CHS
-
DSM
9h 55m
2 stops
Southwest Logo
5:40 am - 11:25 am
DSM
-
CHS
4h 45m
1 stop
$380Southwest
Fri, Jun 19 - Tue, Jun 23
Southwest Logo
5:55 pm - 11:30 pm
CHS
-
DSM
6h 35m
1 stop
Southwest Logo
3:45 pm - 9:25 pm
DSM
-
CHS
4h 40m
1 stop
$381Southwest
Wed, Jun 17 - Wed, Jun 24
Southwest Logo
4:15 pm - 10:45 pm
CHS
-
DSM
7h 30m
2 stops
Southwest Logo
5:20 am - 1:30 pm
DSM
-
CHS
7h 10m
2 stops
$385Southwest
Fri, Jun 19 - Tue, Jun 23
Southwest Logo
4:45 pm - 11:30 pm
CHS
-
DSM
7h 45m
2 stops
Southwest Logo
3:45 pm - 9:25 pm
DSM
-
CHS
4h 40m
1 stop
$386Southwest
Fri, Jun 19 - Tue, Jun 23
Southwest Logo
4:45 pm - 11:30 pm
CHS
-
DSM
7h 45m
2 stops
Southwest Logo
5:20 am - 1:30 pm
DSM
-
CHS
7h 10m
2 stops
$391Southwest
Booking Insights

KAYAK's insights & trends for Charleston to Des Moines flights

Get data-powered insights and trends into flights from Charleston to Des Moines to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Charleston to Des Moines?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Charleston to Des Moines departing in June.

What is the cheapest month to fly from Charleston to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Des Moines is April, where tickets cost $316 (return) on average. On the other hand, the most expensive months are November and June, where the average cost of round-trip tickets is $537 and $502 respectively.

Find deals

Good to know

Low seasonFebruary
Cheapest flight$150
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 35% increase in price.
Flight from Charleston to Des Moines

When to book flights from Charleston to Des Moines

Are your dates flexible? Find out the best times to travel from Charleston to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Des Moines

  • What is the cheapest flight from Charleston to Des Moines?

    In the last 7 days, the lowest price for a flight from Charleston to Des Moines was $150 for a one-way ticket and $335 for a round-trip.

  • Do I need a passport to fly between Charleston and Des Moines?

    A passport is not required to fly from Charleston to Des Moines.

  • Which aircraft models fly most regularly from Charleston to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Des Moines?

    oneworld, and SkyTeam are the airline alliances operating flights between Charleston and Des Moines, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Charleston to Des Moines, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Charleston to Des Moines are Delta and American Airlines. With an average price for the route of $478 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $370 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Charleston to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Charleston with another airline. Booking your flights between Charleston and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8419 reviews
7.8Comfort
7.8Entertainment
8.5Crew
8.1Boarding
7.2Food
Airline reviews

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

6.0 GoodAnonymous, May 2026
ATL - ECP
Read more Delta reviews

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

Movies on my phone are great. It would be nice to have a gluten free snack option.

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Awful, tons of delays, I got into Chicago multiple hours late meaning I hit the very traffic I tried so desperately to avoid. Just empty apologies from American Airlines text alerts. Trash behavior from a trash airline.

The flight attendants were very friendly, efficient, and helpful. The plane was ahead of schedule, and it all went very smoothly. Thank you.

They lost my baggage and I am still struggling to the information and update

We got delayed getting out of DFW for broken overhead bins. Once the flight got underway the captain kept the seatbelt sign lit the entire flight despite little perceptible turbulence, preventing use of the rest rooms and any sort of refreshment service in the main cabin.

Flight delays for communication overall not a good experience uncomfortable on the plane. Person in front of me reclined his seat, putting them inches from my lap.

Everything you need to know for your flight from Charleston to Des Moines

Information on your arrival and departure airports

Charleston (CHS)
Des Moines (DSM)