Which airports can I use when flying from Charleston to Knoxville?

Flights from Charleston to Knoxville usually depart from Charleston (CHS) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Charleston to Knoxville?

Only Economy Class is available on flights from Charleston to Knoxville.

Which airports do connecting flights from Charleston to Knoxville pass through?

Connecting flights from Charleston to Knoxville most commonly pass through: • Atlanta Hartsfield-Jackson (ATL) - 71% of one-stop connections • Charlotte Douglas (CLT) - 29% of one-stop connections

Can I save money by using flexible dates for flights from Charleston to Knoxville?

Yes. Flexible dates can save you up to 37% on flights from Charleston to Knoxville. Saturday is the cheapest departure day at $346 round-trip on average, while Sunday is the most expensive at $547, a difference of $201. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How long is a flight from Charleston to Knoxville?

A nonstop flight from Charleston to Knoxville takes 00m, covering 302 miles.

Do I need a passport to fly from Charleston to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Charleston to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $278 to $1,280. That means the highest observed fare was about 5x higher than the lowest one.

How are flight prices from Charleston to Knoxville looking right now?

One-way fares from Charleston to Knoxville are currently lower than usual. Average one-way flight prices are about $289, which is 8% below the typical average for this route.

How much time can I save by choosing a different layover airport from Charleston to Knoxville?

Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 3h 36m, compared with 3h 58m via Charlotte Douglas (CLT).

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include: • Budget • Alamo • Enterprise Rent-A-Car • Thrifty • Avis

How much should I expect to pay for a Charleston to Knoxville flight?

Round-trip flights from Charleston to Knoxville range from $346 to $578, with an average of $485 over the past 12 months. Anything below $346 counts as a good deal.

Which airline is the cheapest to fly from Charleston to Knoxville?

American Airlines ($319) and Southwest ($330) are the cheapest airlines to fly round-trip from Charleston to Knoxville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Charleston to Knoxville?

Atlanta Hartsfield-Jackson (ATL) is the most popular layover for the Charleston to Knoxville route. 71% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ATL.

What is the cheapest layover airport when flying from Charleston to Knoxville?

Flights via Charlotte Douglas (CLT) offer the most affordable fares, with an average round-trip price of $450. Based on KAYAK data over the past 3 months.

When flying from Charleston to Knoxville which airport offers the shortest layover?

Atlanta Hartsfield-Jackson (ATL) had the shortest average connection time for Charleston to Knoxville layovers at 2h 23m over the past 3 months.

$144 CHEAP FLIGHTS from Charleston to Knoxville (CHS - TYS)

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$278

Typical prices: $346-$578

Multiple Airlines

Wed 10/31Sun 11/4

CHS - TYS • 2 stops

Cheapest one-way

$144

Typical prices: $247-$338

Delta

Wed 11/14

CHS - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Charleston and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

January

Cheapest • 48% price drop

October

Most popular

Good to know

Top layover airports

Charlotte Douglas (CLT)

Cheapest • Avg $450 (round-trip)

Atlanta Hartsfield-Jackson (ATL)

Shortest trip • 3h 36m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Knoxville!

Cheap Flights from Charleston to Knoxville (CHS-TYS)

Cheap flights from Charleston to Knoxville with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Round-trip

One-way

Last minute

Sat, Oct 31 - Wed, Nov 4

3:42 pm - 2:22 pmCHS Charleston-TYS Knoxville McGhee Tyson

46h 40m2 stops Orlando Key West

10:55 am - 7:14 pmTYS Knoxville McGhee Tyson-CHS Charleston

8h 19m1 stop Fort Lauderdale

$278Multiple Airlines

Sat, Oct 31 - Wed, Nov 4

7:52 pm - 9:25 amCHS Charleston-TYS Knoxville McGhee Tyson

13h 33m1 stop Fort Lauderdale

10:55 am - 7:14 pmTYS Knoxville McGhee Tyson-CHS Charleston

8h 19m1 stop Fort Lauderdale

$291Multiple Airlines

Sat, Nov 14 - Sat, Nov 21

6:10 am - 11:55 amCHS Charleston-TYS Knoxville McGhee Tyson

5h 45m1 stop Charlotte Douglas

6:05 pm - 11:55 pmTYS Knoxville McGhee Tyson-CHS Charleston

5h 50m1 stop Charlotte Douglas

$319American Airlines

Sat, Nov 14 - Sat, Nov 21

6:40 am - 12:00 pmCHS Charleston-TYS Knoxville McGhee Tyson

5h 20m1 stop Nashville Intl

7:45 pm - 10:20 amTYS Knoxville McGhee Tyson-CHS Charleston

14h 35m2 stops Nashville Intl Baltimore/Washington

$330Southwest

Mon, Nov 16 - Mon, Nov 23

7:04 pm - 11:59 pmCHS Charleston-TYS Knoxville McGhee Tyson

4h 55m1 stop Atlanta Hartsfield-Jackson

5:40 am - 11:52 amTYS Knoxville McGhee Tyson-CHS Charleston

6h 12m1 stop Atlanta Hartsfield-Jackson

$387Delta

Fri, Nov 20 - Sun, Nov 22

6:34 am - 9:55 amCHS Charleston-TYS Knoxville McGhee Tyson

3h 21m1 stop Atlanta Hartsfield-Jackson

5:40 am - 11:52 amTYS Knoxville McGhee Tyson-CHS Charleston

6h 12m1 stop Atlanta Hartsfield-Jackson

$387Delta

Thu, Dec 10 - Sat, Dec 12

5:04 am - 8:54 amCHS Charleston-TYS Knoxville McGhee Tyson

3h 50m1 stop Charlotte Douglas

2:13 pm - 6:47 pmTYS Knoxville McGhee Tyson-CHS Charleston

4h 34m1 stop Charlotte Douglas

$387American Airlines

Fri, Jan 15 - Sun, Jan 17

6:00 am - 9:12 amCHS Charleston-TYS Knoxville McGhee Tyson

3h 12m1 stop Atlanta Hartsfield-Jackson

6:00 am - 9:42 amTYS Knoxville McGhee Tyson-CHS Charleston

3h 42m1 stop Atlanta Hartsfield-Jackson

$387Delta

Thu, Nov 19 - Sun, Nov 22

2:00 pm - 6:27 pmCHS Charleston-TYS Knoxville McGhee Tyson

4h 27m1 stop Atlanta Hartsfield-Jackson

5:40 am - 8:43 amTYS Knoxville McGhee Tyson-CHS Charleston

3h 03m1 stop Atlanta Hartsfield-Jackson

$387Delta

Sat, Nov 14 - Sat, Nov 21

6:40 am - 7:50 pmCHS Charleston-TYS Knoxville McGhee Tyson

13h 10m2 stops Nashville Intl Baltimore/Washington

7:45 pm - 10:20 amTYS Knoxville McGhee Tyson-CHS Charleston

14h 35m2 stops Nashville Intl Baltimore/Washington

$390Southwest

Price, demand and travel trends for Charleston to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Airlines

Layovers

Which airline is the cheapest to fly from Charleston to Knoxville?: American Airlines ($319) and Southwest ($330) are the cheapest airlines to fly round-trip from Charleston to Knoxville according to KAYAK data over the last 5 days.

Find deals

Low season	January
High season	October
Cheapest flight	$144

Beat the crowds with an average 75% drop in travelers.

The most popular month to fly with an average 50% increase in travelers.

One-way flight from Charleston to Knoxville

When to book flights from Charleston to Knoxville

Are your dates flexible? Find out the best times to travel from Charleston to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Charleston to Knoxville?
Only Economy Class is available on flights from Charleston to Knoxville.
How long is a flight from Charleston to Knoxville?
A nonstop flight from Charleston to Knoxville takes 00m, covering 302 miles.
Do I need a passport to fly from Charleston to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Charleston to Knoxville flight?
Round-trip flights from Charleston to Knoxville range from $346 to $578, with an average of $485 over the past 12 months. Anything below $346 counts as a good deal.
Have flight prices from Charleston to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $278 to $1,280. That means the highest observed fare was about 5x higher than the lowest one.
How are flight prices from Charleston to Knoxville looking right now?
One-way fares from Charleston to Knoxville are currently lower than usual. Average one-way flight prices are about $289, which is 8% below the typical average for this route.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:

• Budget
• Alamo
• Enterprise Rent-A-Car
• Thrifty
• Avis
Which airports can I use when flying from Charleston to Knoxville?
Flights from Charleston to Knoxville usually depart from Charleston (CHS) and arrive at Knoxville McGhee Tyson (TYS).
Which airports do connecting flights from Charleston to Knoxville pass through?
Connecting flights from Charleston to Knoxville most commonly pass through:

• Atlanta Hartsfield-Jackson (ATL) - 71% of one-stop connections
• Charlotte Douglas (CLT) - 29% of one-stop connections
Can I save money by using flexible dates for flights from Charleston to Knoxville?
Yes. Flexible dates can save you up to 37% on flights from Charleston to Knoxville. Saturday is the cheapest departure day at $346 round-trip on average, while Sunday is the most expensive at $547, a difference of $201.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How much time can I save by choosing a different layover airport from Charleston to Knoxville?
Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 3h 36m, compared with 3h 58m via Charlotte Douglas (CLT).

If your dates are flexible, aim for a Saturday departure and avoid flying on Sunday. On this route, Saturday flights average $346, about $201 less than Sunday fares (37% savings) based on the last 12 months.
If you can choose when to travel, plan your Charleston to Knoxville trip for January. Fares historically average $254 round-trip in that month - typically $484 less than the most expensive month, which is September (based on the last 12 months).

More options for your flight from Charleston to Knoxville

Add a hotel or car rental

Airports

Cabin class

Direct Flights

Origins

Other destinations

Return flight

Complete your trip to Knoxville with a hotel stay or car rental

Car rentals in Knoxville

Hotels in Knoxville

Vacations in Knoxville

CHS - TYS

$144 Find Cheap Flights from Charleston to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Charleston to Knoxville (CHS-TYS)

Cheap flights from Charleston to Knoxville with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Price, demand and travel trends for Charleston to Knoxville flights

Which airline is the cheapest to fly from Charleston to Knoxville?

What’s the most popular layover airport when flying from Charleston to Knoxville?

What is the cheapest layover airport when flying from Charleston to Knoxville?

When flying from Charleston to Knoxville which airport offers the shortest layover?

Key details for Charleston to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Charleston to Knoxville

Your Charleston to Knoxville flight questions, answered

Your guide to booking Charleston to Knoxville flights

More options for your flight from Charleston to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Charleston to Knoxville

Find direct flights to and from Charleston and Knoxville

Flights from domestic origins to Knoxville

Flights to other popular destinations

Find deals for your return flight