TYS - CHS

$132 Find Cheap Flights from Knoxville to Charleston

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Charleston departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Charleston

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Charleston, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Charleston, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$253
Multiple Airlines
Wed 3/18Sun 3/22
TYS - CHS • 1 stop
Cheapest one-way
$132
Typical prices: $356-$462
Southwest
Wed 5/13
TYS - CHS • 1 stop
Top airlines
Southwest
Cheapest • from $271 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Charleston!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Charleston (TYS-CHS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Charleston that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Charleston

Wed, Mar 18 - Sun, Mar 22
Multiple Airlines Logo
11:30 am - 10:13 pm
TYS
-
CHS
10h 43m
1 stop
Multiple Airlines Logo
8:59 pm - 11:32 pm
CHS
-
TYS
26h 33m
1 stop
$253Multiple Airlines
Sat, Apr 11 - Wed, Apr 15
Southwest Logo
7:45 am - 2:05 pm
TYS
-
CHS
6h 20m
1 stop
Southwest Logo
2:25 pm - 8:50 pm
CHS
-
TYS
6h 25m
1 stop
$271Southwest
Sat, Apr 11 - Wed, Apr 15
Southwest Logo
6:40 am - 2:05 pm
TYS
-
CHS
7h 25m
2 stops
Southwest Logo
6:40 am - 12:00 pm
CHS
-
TYS
5h 20m
1 stop
$276Southwest
Mon, Mar 16 - Tue, Mar 17
Delta Logo
6:38 pm - 12:16 am
TYS
-
CHS
5h 38m
1 stop
Delta Logo
5:27 am - 11:17 am
CHS
-
TYS
5h 50m
1 stop
$279Delta
Sat, Apr 11 - Wed, Apr 15
Southwest Logo
6:40 am - 2:05 pm
TYS
-
CHS
7h 25m
2 stops
Southwest Logo
12:00 pm - 8:50 pm
CHS
-
TYS
8h 50m
2 stops
$281Southwest
Wed, Apr 1 - Sun, Apr 5
Multiple Airlines Logo
9:15 am - 10:13 pm
TYS
-
CHS
12h 58m
2 stops
Multiple Airlines Logo
8:59 pm - 11:20 pm
CHS
-
TYS
26h 21m
1 stop
$282Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
Multiple Airlines Logo
7:00 am - 9:59 pm
TYS
-
CHS
14h 59m
1 stop
Multiple Airlines Logo
3:01 pm - 6:32 pm
CHS
-
TYS
27h 31m
1 stop
$284Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
Multiple Airlines Logo
7:00 am - 9:59 pm
TYS
-
CHS
14h 59m
1 stop
Multiple Airlines Logo
6:35 pm - 11:38 pm
CHS
-
TYS
29h 03m
2 stops
$285Multiple Airlines
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
3:35 pm - 10:41 pm
TYS
-
CHS
7h 06m
1 stop
Multiple Airlines Logo
7:00 am - 8:42 pm
CHS
-
TYS
13h 42m
1 stop
$297Multiple Airlines
Tue, Mar 17 - Fri, Mar 20
Multiple Airlines Logo
3:00 pm - 10:13 pm
TYS
-
CHS
7h 13m
1 stop
Multiple Airlines Logo
8:07 am - 9:50 am
CHS
-
TYS
25h 43m
1 stop
$300Multiple Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Charleston flights

Get data-powered insights and trends into flights from Knoxville to Charleston to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Charleston?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Charleston were found on Southwest ($271) and Delta ($279).

Good to know

Low seasonAugust
Cheapest flight$132
Best time to beat the crowds with an average 27% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Knoxville to Charleston

When to book flights from Knoxville to Charleston

Are your dates flexible? Find out the best times to travel from Knoxville to Charleston based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Charleston

  • What is the cheapest flight from Knoxville to Charleston?

    In the last 3 days, the lowest price for a flight from Knoxville to Charleston was $132 for a one-way ticket and $253 for a round-trip.

  • Do I need a passport to fly between Knoxville and Charleston?

    No

  • Which aircraft models fly most regularly from Knoxville to Charleston?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Charleston?

    SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and Charleston, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Charleston, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Charleston are Delta and American Airlines. With an average price for the route of $412 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $417 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Charleston?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Charleston.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Charleston?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Charleston from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Charleston?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Charleston with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and CHS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Charleston?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Charleston from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Charleston

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Charleston. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Charleston? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8162 reviews
7.2Food
7.9Comfort
7.8Entertainment
8.1Boarding
8.5Crew
Airline reviews

First class and monitors weren’t working for mine & my husbands. Eventually fixed, but quite annoyed as we bought first class. Also, No foot rests.

6.0 GoodAnonymous, Feb 2026
SEA - OGG
Read more Delta reviews

First class and monitors weren’t working for mine & my husbands. Eventually fixed, but quite annoyed as we bought first class. Also, No foot rests.

Prior to takeoff, the pilot told us there was a possibility of not being able to land and going to Portland. Well that happened, we took off and then did 8 loops around Spokane before the pilot told us we ran out of fuel and had to go to Portland. So for a 35 minute flight we have now been on the plane for 3 hours (boarded at 6:50 am and landed in Portland at 10:30). Then, we just sat in Portland's airport with no updates of when we can start heading back. All of a sudden, our pilots and crew just left, leaving us stranded in a different city and state. We continued to sit in Portland until we finally got a new crew assigned and boarded the plane (This was from 10:30-2). We then sat on the plane for an additional hour before take off because they had to count us multiple times. We finally landed in Spokane at 3:55 PM. So a flight that should have taken at max an hour took us 10 hours and we missed the majority of the recruiting event we went for.

It was delayed but other than that it was great.

Got on the plane and sat there for an hour before departure.

Second flight in a row where the entertainment system is broken. 5 hour long flight with no entertainment and flight attendants did not seem interested in resolving the matter. Very shocked to be treated this poorly considering I paid for a first class experience and have Diamond Medallion status.

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

Generally good. Flight left on time and the seats are comfortable. Plenty of space in front if you in you choose a comfort plus seat, completely worth spending the extra money given the amount of hours the flight lasts. The food tastes good but I would say it’s a the amount is too little. The crew was friendly and efficient. There was a some turbulence at different points into the flight. American Airlines has good deals to NZ if you book with plenty of time before you plan on going.

the plane was so hot!! the air-conditioning was barely blowing. The flight was delayed, and we had to sit on the hot plane before take off for an extended amount of time, waiting on international passengers. Would not have been so bad if it was not so hot. They said it would get better after take off, but it did not.

They are always late and seats was also not having working charger

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

did not have enough meal for first class passengers so offer us snack

Arrived 40 min early which was great - sat in runway for 35 min so no gain. Then waited for luggage 45 min. They need to staff accordingly knowing its one of the busiest week in Phx

My flight got rerouted due to crew rest. I was sent to Dallas customer service was not very polite. Was given a $40 room voucher for Motel 6 and $12 to eat with. It delayed me by a day. Where if I would have just stuck with my original flight Arizona was delayed to Cleveland and I could have made it home. They put me on a 9:00 flight out of Dallas to Cleveland without my knowledge or consent. When originally I was told it would be 8:45 a.m. on February 1st. I told them I could not take the 9:00 flight because I did not have anybody to pick me up from the airport at that time. I'm extremely disappointed in how I was treated. And I will not fly American Airlines again.

I am very appreciative of the help provided to me by Dennis and Whitney. I had lost my phone at EWR airport and they were very kind in assisting me. This included advice on how to file a report and also helping me connect with family. The pilot was also great about keeping passengers updated on the flight progress with regular communications over the system.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

Old equipment, needs upgrade and seat comfort. Internet didn't work 75% or the time.

Everything you need to know for your flight from Knoxville to Charleston

Information on your arrival and departure airports