$111 Find Cheap Flights from Charleston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Charleston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$588
Bogotá
Bogotá1 stop$284
Sao Paulo
Sao Paulo1 stop$615
Santiago
Santiago1 stop$664
Cartagena
Cartagena1 stop$456
Quito
Quito2 stops$1,214
Guayaquil
Guayaquil1 stop$513
Cusco
Cusco2 stops$944
Montevideo
Montevideo2 stops$1,426
Lima
Lima1 stop$588
Bogotá
Bogotá1 stop$284
Sao Paulo
Sao Paulo1 stop$615
Santiago
Santiago1 stop$664
Cartagena
Cartagena1 stop$456
Quito
Quito2 stops$1,214
Guayaquil
Guayaquil1 stop$513
Cusco
Cusco2 stops$944
Montevideo
Montevideo2 stops$1,426

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Thu, Oct 30 - Wed, Nov 5
Spirit Airlines Logo
10:11 am - 1:15 pmCHS-BOG
28h 04m1 stop
Spirit Airlines Logo
3:05 pm - 10:45 amBOG-CHS
19h 40m1 stop
$284Spirit Airlines
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Thu, Oct 30 - Wed, Nov 5
 Logo
10:11 am - 1:15 pmCHS-BOG
28h 04m1 stop
 Logo
3:40 pm - 10:45 amBOG-CHS
19h 05m2 stops
Tue, Oct 28 - Tue, Nov 4
JetBlue Logo
5:20 pm - 1:32 pmCHS-MDE
21h 12m1 stop
JetBlue Logo
2:10 pm - 4:22 pmMDE-CHS
26h 12m1 stop
$400JetBlue
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Fri, Oct 31 - Tue, Nov 4
JetBlue Logo
6:05 am - 1:09 pmCHS-CTG
8h 04m1 stop
JetBlue Logo
3:30 pm - 1:19 pmCTG-CHS
21h 49m1 stop
$456JetBlue
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Fri, Feb 20 - Wed, Feb 25
American Airlines Logo
5:51 am - 3:01 pmCHS-CTG
9h 10m1 stop
American Airlines Logo
4:50 pm - 11:29 pmCTG-CHS
6h 39m1 stop
$515American Airlines
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Fri, Feb 20 - Wed, Feb 25
American Airlines Logo
5:27 am - 8:15 pmCHS-CTG
14h 48m2 stops
American Airlines Logo
4:50 pm - 12:18 pmCTG-CHS
19h 28m2 stops
$519American Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 18
Delta Logo
7:59 pm - 12:05 pmCHS-BOG
17h 06m2 stops
Delta Logo
5:00 am - 11:39 pmBOG-CHS
17h 39m2 stops
$523Delta
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Mon, Nov 3 - Fri, Nov 28
Delta Logo
7:05 pm - 12:05 pmCHS-BOG
17h 00m2 stops
Delta Logo
3:55 pm - 11:57 pmBOG-CHS
8h 02m1 stop
$533Delta
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Fri, Oct 17 - Fri, Oct 24
LATAM Airlines Logo
12:54 pm - 7:15 pmCHS-BOG
7h 21m1 stop
LATAM Airlines Logo
2:55 pm - 11:59 pmBOG-CHS
8h 04m1 stop
$582LATAM Airlines
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Fri, Oct 17 - Thu, Oct 23
LATAM Airlines Logo
6:40 am - 7:58 pmCHS-BOG
14h 18m2 stops
LATAM Airlines Logo
1:35 am - 6:00 pmBOG-CHS
15h 25m2 stops
$586LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charleston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to South America is January, when tickets cost $585 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $1,572 and $850 respectively.

What’s the cheapest day of the week to fly from Charleston to South America?

The average price of all round-trip flights from Charleston to South America clicked on KAYAK for each day over the last 12 months.

For Charleston to South America, Monday is the cheapest day to fly on average and Friday is the most expensive. Flying from South America back to Charleston, the best deals are generally found on Wednesday, with Thursday being the most expensive.

Good to know

Low seasonApril
Cheapest flight$111
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 30% increase in price.
Flight from Charleston to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $659 on average. Morning departures are around 10% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally at night, which is peak travel time and where the average cost of a ticket is $833.

Reviews of the top 3 airlines serving from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7954 reviews
8.5Crew
7.3Food
7.9Comfort
7.9Entertainment
8.2Boarding
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

The food was terrible especially for a 15 hour international flight. The crew was unpleasant as well.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

American airlines suck they delay the flights all the time made me sleep in an airport because my flight was delayed and I miss my connecting flight

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Don’t know they cancelled the flight day before I was to leave. They sent a email at 9:00 pm at night saying they cancelled. That is the smooth way to say we don’t want your business! I think they didn’t have enough people booking so they cancelled the flight! It’s all about the money anymore there is no honesty in business.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

It took way too long to diagnose and solve the problem of a broken crew member cabin seat. Though compensation for the volunteer who left the flight was very kind.

The entertainment package was vast and the selections were very current. Keep updating it was great.

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