$277 Find Cheap Flights from Charleston to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Charleston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$690
Bogotá
Bogotá1 stop$536
Sao Paulo
Sao Paulo2 stops$804
Santiago
Santiago1 stop$855
Cartagena
Cartagena1 stop$465
Quito
Quito2 stops$454
Guayaquil
Guayaquil2 stops$781
Cusco
Cusco2 stops$1,029
Montevideo
Montevideo2 stops$941
Lima
Lima1 stop$690
Bogotá
Bogotá1 stop$536
Sao Paulo
Sao Paulo2 stops$804
Santiago
Santiago1 stop$855
Cartagena
Cartagena1 stop$465
Quito
Quito2 stops$454
Guayaquil
Guayaquil2 stops$781
Cusco
Cusco2 stops$1,029
Montevideo
Montevideo2 stops$941

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Mon, Jul 20 - Wed, Jul 29
JetBlue Logo
6:40 pm - 11:35 am
CHS
-
CTG
17h 55m
1 stop
JetBlue Logo
12:35 pm - 5:39 pm
CTG
-
CHS
28h 04m
1 stop
$465JetBlue
Thu, Nov 5 - Mon, Nov 9
Delta Logo
5:30 am - 2:15 pm
CHS
-
CTG
8h 45m
1 stop
Delta Logo
3:25 pm - 11:56 pm
CTG
-
CHS
8h 31m
1 stop
$523Delta
Sat, Oct 24 - Sun, Nov 1
Multiple Airlines Logo
6:50 pm - 5:30 am
CHS
-
BOG
11h 40m
1 stop
Multiple Airlines Logo
8:35 pm - 9:59 am
BOG
-
CHS
13h 24m
2 stops
$536Multiple Airlines
Mon, Jul 27 - Thu, Jul 30
JetBlue Logo
6:40 pm - 11:35 am
CHS
-
CTG
17h 55m
1 stop
JetBlue Logo
12:35 pm - 5:50 pm
CTG
-
CHS
28h 15m
1 stop
$544JetBlue
Sat, Aug 29 - Sun, Sep 20
Multiple Airlines Logo
8:14 pm - 5:25 am
CHS
-
MDE
10h 11m
1 stop
Multiple Airlines Logo
8:00 pm - 10:15 am
MDE
-
CHS
13h 15m
1 stop
$550Multiple Airlines
Fri, Sep 25 - Mon, Sep 28
American Airlines Logo
7:37 pm - 12:35 pm
CHS
-
CTG
17h 58m
2 stops
American Airlines Logo
1:35 pm - 11:43 pm
CTG
-
CHS
9h 08m
1 stop
$558American Airlines
Fri, Sep 25 - Mon, Sep 28
American Airlines Logo
6:30 pm - 12:35 pm
CHS
-
CTG
19h 05m
1 stop
American Airlines Logo
1:35 pm - 11:43 pm
CTG
-
CHS
9h 08m
1 stop
$563American Airlines
Sat, Aug 29 - Sun, Sep 20
Avianca Logo
8:14 pm - 5:25 am
CHS
-
MDE
10h 11m
1 stop
Avianca Logo
10:40 pm - 10:15 am
MDE
-
CHS
10h 35m
1 stop
$590Avianca
Thu, Dec 3 - Mon, Dec 7
LATAM Airlines Logo
6:30 am - 8:20 pm
CHS
-
BOG
13h 50m
2 stops
LATAM Airlines Logo
10:55 am - 11:56 pm
BOG
-
CHS
13h 01m
2 stops
$653LATAM Airlines
Tue, Oct 20 - Mon, Oct 26
LATAM Airlines Logo
4:30 pm - 5:00 am
CHS
-
LIM
13h 30m
1 stop
LATAM Airlines Logo
12:00 pm - 9:42 am
LIM
-
CHS
20h 42m
1 stop
$690LATAM Airlines
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charleston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to South America is September, when tickets cost $156 (return) on average. On the other hand, the most expensive months are May and October, when the average cost of round-trip tickets is $699 and $647 respectively.

Good to know

Low seasonOctober
Cheapest flight$277
Best time to beat the crowds with an average 7% drop in price.
Flight from Charleston to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8396 reviews
7.8Entertainment
7.2Food
8.5Crew
7.8Comfort
8.1Boarding
Airline reviews

Flight delayed four separate times. I’m now one hour hours late to landing.

2.0 MediocreTravis, Jun 2026
SFO - LAX
Read more Delta reviews

Flight delayed four separate times. I’m now one hour hours late to landing.

worst flight ever from Delta, it got delayed and kept on delaying..

Should never have had to go to Detroit from Orlando back to Tennessee!

Got rerouted from a straight flight from Orlando to Atlanta to Knoxville to a flight from Orlando to Detroit to Knoxville! Seriously!! Flight delay out of Detroit! Long day for what should have been a pretty easy travel day!

Two delays on two separate planes with parts they could not easily find and replace.

Checkin was good, fllight ws good. Onlly complaint is lack of foot on 6 hour flight from Seattle to Boston. Snacks were flimsy - chips and cookies. could have offered something more substantial for such a long flight. I know you can buy food in airport but for the price you pay for a ticket, they should step up for the passengers.

Only beverages were offered to first class and I thought the flight attendant could have also served the Delta Comfort as well instead of sitting down and staring at her phone and walking past all of us to the back of the plane to charge her phone more. There was a complete lack of turbulence and was safe enough for flights attendant to walk around in the front of the plane, collect trash and serve a few people water and turn off the seat belt light. Also didn’t enforce people putting their seats into the upright position and allowed two passengers to remain reclined during landing. They seemed out to lunch completely. Usually my experience on Delta is much better.

Long story short, it was one of the better flight experiences I've had in some time when compared with other airlines.

Flight was great! This flight from Atlanta was even better than when I paid for Comfort from SNA to Atlanta.

Connection flights should be spaced out farther because too close I missed my connection.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

Leave on time. We waited on the plane for hour hours and it was hot and smelly

Two hours delay, probably one hour because they didn’t bring catering and they had to bring water in board. There a change of aircraft. But delays galore at CLT so it must be a CLT and/or AA operation issue. The 1 hr additional delays because nobody could bring 2 packs of water sooner is probably the best example of this airline operates

Flight was delayed 5 hours. Initial reason for delay was 'maintenance' - which makes sense. Then, the additional 2 hours continued to say it was maintenance - when I know EWR had a 2 hour delay. AA did not say that. Additionally, when boarding, there was only one agent at the counter for a long time - until another came to help. After boarding, we had to wait another 45 minutes due to 'no catering'. So while we waited for catering, AA continued to board additional passengers - which seemed odd - and raised questions about what really was going on. I sat in First Class. During the flight, the flight crew allowed a significant number of non-First Class passengers to use the front bathroom - which created a very crowded environment in First Class which was uncomfortable. This also delayed First Class passengers from using the bathroom. Overall, horrible experience.

The Charleston, WV airport was cute. Very good staff and small enough to feel comfortable. The plane had more leg room than bigger planes. Much more comfortable.

Another uncoordinated American experience. Always surprises me at DFW for them of all places. Have to take this flight as there are no other good time options. We knew from the start that something was wrong, but the pilot wouldn't tell us. I just watched my Kayak app grow the delay by 10 minutes as it went to 3.5 hours. They were uncoordinated with maintenance (as maintenance, when finally arriving, knew within 15 minutes the plane wasn't going. No 'sorry' or 'this is what is going on' comment. The pilot seemed unfazed / didn't care about the process we were going through.

The seats. The seat in front of me was awful and when the guy sat down, it flew back and hit my head when I was putting my backpack under the seat, It didn't make for a pleasant experience,

Luggage did not make it onto my plane. Business seats were economy with empty row seat. Just horrible experience. Why would the company allow for transfers that don’t give employees enough time to transfer luggages??

I’ve got 31F seat and window seat . My 2 co passengers was AA crew members and they were very rude attitude and when I was going to use bathroom their gestures was very different and awkward and the guy beside me completely occupied the hand rest and I was really uncomfortable

The gate experience at LAX was abysmal (same for the arrival experience two days prior). Despite the LAX -> SAT schedule of two flights daily, our departure gate was at a smaller hub that we had to be bussed to from Terminal 4. Fortunately, I arrived at LAX extra early and had time to spare, but if I had not known, I might have missed my flight. I looked at the LAX airport map in the AA app and there was no indication of the additional boarding process. Lastly the gate area we were bussed to was crowded with limited food and beverage options. On flight, the fight attendant was hospitable and attentive, the flight was smooth, and AA's free (and working) wifi for AA members were all on the positive side.

It was so much better than expected, Ohare is not such a pleasant experience but American Airlines with the new, clean aeroplane and free Wi-Fi was outstanding and the crew so pleasant and helpful.

Everything you need to know for your flight to South America

Information on your arrival and departure airports