$120 Find Cheap Flights from Charleston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Charleston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$555
Bogotá
Bogotá1 stop$338
Sao Paulo
Sao Paulo1 stop$650
Cartagena
Cartagena1 stop$306
Santiago
Santiago1 stop$684
Quito
Quito1 stop$720
Guayaquil
Guayaquil1 stop$499
Cusco
Cusco2 stops$898
Montevideo
Montevideo2 stops$1,175
Lima
Lima2 stops$555
Bogotá
Bogotá1 stop$338
Sao Paulo
Sao Paulo1 stop$650
Cartagena
Cartagena1 stop$306
Santiago
Santiago1 stop$684
Quito
Quito1 stop$720
Guayaquil
Guayaquil1 stop$499
Cusco
Cusco2 stops$898
Montevideo
Montevideo2 stops$1,175

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Fri, Sep 19 - Sun, Sep 28
Spirit Airlines Logo
10:31 am - 12:25 amCHS-MDE
14h 54m1 stop
Spirit Airlines Logo
1:24 am - 9:26 amMDE-CHS
7h 02m1 stop
$277Spirit Airlines
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Fri, Sep 19 - Sun, Sep 28
Spirit Airlines Logo
10:31 am - 1:00 pmCHS-MDE
27h 29m2 stops
Spirit Airlines Logo
1:24 am - 9:26 amMDE-CHS
7h 02m1 stop
$295Spirit Airlines
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Fri, Sep 19 - Mon, Sep 29
 Logo
3:33 pm - 12:00 pmCHS-BOG
21h 27m1 stop
 Logo
12:55 pm - 8:37 amBOG-CHS
18h 42m1 stop
Thu, Aug 21 - Thu, Aug 28
 Logo
2:50 pm - 12:00 pmCHS-BOG
22h 10m1 stop
 Logo
1:54 pm - 7:12 pmBOG-CHS
28h 18m1 stop
Sun, Oct 12 - Sat, Oct 25
American Airlines Logo
4:30 pm - 12:25 pmCHS-CTG
20h 55m2 stops
American Airlines Logo
1:25 pm - 10:26 amCTG-CHS
20h 01m2 stops
$495American Airlines
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Sun, Oct 12 - Sat, Oct 25
American Airlines Logo
7:44 pm - 12:25 pmCHS-CTG
17h 41m1 stop
American Airlines Logo
1:25 pm - 11:59 pmCTG-CHS
9h 34m1 stop
$500American Airlines
Find Deal
Sat, Sep 27 - Fri, Oct 3
Delta Logo
6:20 am - 1:16 pmCHS-CTG
7h 56m1 stop
Delta Logo
3:42 am - 9:16 amCTG-CHS
28h 34m2 stops
$504Delta
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Sat, Sep 27 - Sat, Oct 4
Delta Logo
6:20 am - 1:16 pmCHS-CTG
7h 56m1 stop
Delta Logo
2:33 pm - 8:48 pmCTG-CHS
29h 15m1 stop
$508Delta
Find Deal
Wed, Nov 12 - Mon, Nov 24
LATAM Airlines Logo
12:15 pm - 7:30 pmCHS-BOG
7h 15m1 stop
LATAM Airlines Logo
9:00 am - 4:51 pmBOG-CHS
7h 51m1 stop
$516LATAM Airlines
Find Deal
Wed, Nov 12 - Mon, Nov 24
LATAM Airlines Logo
10:37 am - 8:20 pmCHS-BOG
9h 43m2 stops
LATAM Airlines Logo
9:00 am - 4:51 pmBOG-CHS
7h 51m1 stop
$520LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charleston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to South America is January, when tickets cost $585 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $1,572 and $850 respectively.

What’s the cheapest day of the week to fly from Charleston to South America?

The average price of all round-trip flights from Charleston to South America clicked on KAYAK for each day over the last 12 months.

For Charleston to South America, Monday is the cheapest day to fly on average and Friday is the most expensive. Flying from South America back to Charleston, the best deals are generally found on Wednesday, with Thursday being the most expensive.


Good to know

Low seasonApril
Cheapest flight$120
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 34% increase in price.
Flight from Charleston to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $659 on average. Morning departures are around 10% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally at night, which is peak travel time and where the average cost of a ticket is $833.

Reviews of the top 3 airlines serving from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
7.9Comfort
8.5Crew
8.2Boarding
7.3Food
7.9Entertainment
Airline reviews

Delayed and took off even later than the scheduled delay time

8.0 ExcellentAnonymous, Jul 2025DTW - SEA
Read more Delta reviews

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Only issue was with seating. The economy fare we purchased did say there was no guarantee the three people in our party would be seated together, and we were not. At the gate, the agent told us more specifically, the fare we purchased meant we would be seated in middle seats only. This should just be made more obvious.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Everything was good until we were boarding our connection flight in Atlanta, we were told to gate check our carry-on, but when we got inside the plane, there was plenty of room in the overhead.

Did not know my son and I had different seating arrangements. He was fine, but it was disappointing.

Flight was canceled, and no effort was made to help with rebooking, no hotel vouchers, no car transportation and minimal food voucher and most places for food were closed by the time the voucher was given. Waited for 3 hours for bags. Simply the worst travel experience I have ever had

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

entertainment was not good; the shoulder strap on Business class seat did not sit well across the body (more like across the neck); the food was not hot and the special meal promoted by insert in the menu was not available to us

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

It was a very good flight, no entertainment is the reason for not checking that box.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

The plane was broken so we had to change planes.

The flight got delayed 2.5 hrs due to a maintenance issue that cause a domino effect. American should have spare planes for when something like this happens.

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