CHS - SCL

$406 Find Cheap Flights from Charleston to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Santiago departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$664
LATAM Airlines
Thu 11/13Sun 11/16
CHS - SCL • 1 stop
Cheapest one-way
$406
Multiple Airlines
Thu 12/25
CHS - SCL • 2 stops
Top airlines
LATAM Airlines
Cheapest • from $664 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charleston to Santiago (CHS-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Santiago

Thu, Nov 13 - Sun, Nov 16
LATAM Airlines Logo
6:28 pm - 7:40 amCHS-SCL
11h 12m1 stop
LATAM Airlines Logo
4:35 am - 10:50 pmSCL-CHS
20h 15m2 stops
$664LATAM Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
United Airlines Logo
11:25 am - 8:50 amCHS-SCL
19h 25m2 stops
United Airlines Logo
10:45 pm - 1:55 pmSCL-CHS
17h 10m2 stops
$669United Airlines
Find Deal
Tue, Mar 17 - Fri, Mar 27
United Airlines Logo
4:50 pm - 7:50 amCHS-SCL
14h 00m1 stop
United Airlines Logo
9:45 pm - 3:57 pmSCL-CHS
19h 12m1 stop
$704United Airlines
Find Deal
Tue, Mar 17 - Fri, Mar 27
LATAM Airlines Logo
12:15 pm - 2:10 pmCHS-SCL
24h 55m3 stops
LATAM Airlines Logo
10:35 am - 6:53 pmSCL-CHS
33h 18m2 stops
$709LATAM Airlines
Find Deal
Tue, Nov 18 - Mon, Nov 24
Multiple Airlines Logo
6:11 pm - 5:30 amCHS-SCL
33h 19m3 stops
Multiple Airlines Logo
3:50 am - 7:26 amSCL-CHS
29h 36m3 stops
$936Multiple Airlines
Find Deal
Tue, Nov 18 - Tue, Nov 25
Multiple Airlines Logo
6:11 pm - 5:30 amCHS-SCL
33h 19m3 stops
Multiple Airlines Logo
7:25 am - 7:26 amSCL-CHS
26h 01m2 stops
$1,000Multiple Airlines
Find Deal
Thu, Dec 25 - Sat, Jan 3
American Airlines Logo
6:14 pm - 9:25 amCHS-SCL
13h 11m1 stop
American Airlines Logo
10:25 pm - 8:47 amSCL-CHS
12h 22m1 stop
$1,855American Airlines
Find Deal
Thu, Dec 25 - Sat, Jan 3
Delta Logo
8:35 am - 6:35 amCHS-SCL
20h 00m2 stops
Delta Logo
6:30 pm - 1:56 pmSCL-CHS
21h 26m2 stops
$1,944Delta
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Thu, Dec 25 - Sat, Jan 3
Copa Airlines Logo
10:00 am - 6:01 amCHS-SCL
18h 01m2 stops
Copa Airlines Logo
5:44 am - 10:24 amSCL-CHS
30h 40m2 stops
$2,022Copa Airlines
Find Deal
Thu, Dec 25 - Sat, Jan 3
American Airlines Logo
6:14 pm - 9:25 amCHS-SCL
13h 11m1 stop
American Airlines Logo
11:55 pm - 2:18 pmSCL-CHS
16h 23m2 stops
$2,085American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Charleston to Santiago flights

Get data-powered insights and trends into flights from Charleston to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Charleston to Santiago?

The average price of all round-trip flights from Charleston to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Charleston to Santiago, you should consider leaving on a Thursday and avoid Tuesdays if you are looking for the best rates. For your return to Charleston, you’ll find the best rates on Wednesdays and the most expensive ones on Thursdays.

Good to know

Low seasonSeptember
Cheapest flight$406
Best time to beat the crowds with an average 37% drop in price.
Most popular time to fly and prices are also 17% lower on average.
Flight from Charleston to Santiago

When to book flights from Charleston to Santiago

Are your dates flexible? Find out the best times to travel from Charleston to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Santiago

  • What is the cheapest flight from Charleston to Santiago?

    In the last 3 days, the lowest price for a flight from Charleston to Santiago was $406 for a one-way ticket and $664 for a round-trip.

  • Do I need a passport to fly between Charleston and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Charleston.

  • Which airports will I be using when flying from Charleston to Santiago?

    When flying out of Charleston you will be using Charleston. You will be landing at Santiago, also known as Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Charleston to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Santiago?

    SkyTeam is the only airline alliance operating flights between Charleston and Santiago.

  • Which is the best airline for flights from Charleston to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Charleston to Santiago are Delta and LATAM Airlines. With an average price for the route of $852 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $1,072 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Charleston to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Charleston with another airline. Booking your flights between Charleston and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7981 reviews
7.9Entertainment
8.2Boarding
8.5Crew
7.3Food
7.9Comfort
Airline reviews

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

6.0 GoodDavid, Oct 2025JFK - KEF
Read more Delta reviews

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Old plane and old configuration/seats but still comfortable for a morning flight

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

We were delayed, which I think had to do with air traffic control. Otherwise, everything was great.

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Everything you need to know for your flight from Charleston to Santiago

Information on your arrival and departure airports

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