CHS - SCL

$684 Find Cheap Flights from Charleston to Santiago

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Santiago departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santiago, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Charleston to Santiago (CHS-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Santiago

Wed, Oct 29 - Tue, Nov 4
LATAM Airlines Logo
12:54 pm - 7:40 amCHS-SCL
17h 46m1 stop
LATAM Airlines Logo
11:10 pm - 10:20 amSCL-CHS
13h 10m1 stop
$684LATAM Airlines
Find Deal
Wed, Oct 29 - Tue, Nov 4
American Airlines Logo
3:31 pm - 8:55 amCHS-SCL
16h 24m2 stops
American Airlines Logo
11:15 pm - 2:31 pmSCL-CHS
17h 16m1 stop
$688American Airlines
Find Deal
Wed, Jan 21 - Mon, Feb 2
LATAM Airlines Logo
7:45 am - 6:10 amCHS-SCL
20h 25m1 stop
LATAM Airlines Logo
11:15 pm - 5:59 pmSCL-CHS
20h 44m1 stop
$704LATAM Airlines
Find Deal
Sat, Nov 22 - Sun, Nov 30
LATAM Airlines Logo
8:05 am - 6:35 amCHS-SCL
20h 30m2 stops
LATAM Airlines Logo
11:10 pm - 9:31 amSCL-CHS
12h 21m1 stop
$764LATAM Airlines
Find Deal
Sat, Nov 22 - Sun, Nov 30
Delta Logo
8:05 am - 7:40 amCHS-SCL
21h 35m1 stop
Delta Logo
11:10 pm - 10:48 pmSCL-CHS
25h 38m1 stop
$769Delta
Find Deal
Thu, Sep 25 - Mon, Sep 29
Delta Logo
4:44 pm - 7:00 amCHS-SCL
13h 16m1 stop
Delta Logo
8:50 am - 11:48 pmSCL-CHS
15h 58m2 stops
$784Delta
Find Deal
Wed, Oct 29 - Tue, Nov 4
Copa Airlines Logo
10:00 am - 5:58 amCHS-SCL
18h 58m2 stops
Copa Airlines Logo
12:20 pm - 10:08 amSCL-CHS
23h 48m2 stops
$857Copa Airlines
Find Deal
Thu, Sep 25 - Mon, Sep 29
American Airlines Logo
10:10 am - 7:55 amCHS-SCL
20h 45m1 stop
American Airlines Logo
9:55 pm - 9:39 amSCL-CHS
12h 44m1 stop
$1,064American Airlines
Find Deal
Thu, Jan 15 - Wed, Jan 21
Air Canada Logo
6:00 am - 7:00 amCHS-SCL
23h 00m2 stops
Air Canada Logo
8:55 pm - 2:48 pmSCL-CHS
19h 53m2 stops
$1,807Air Canada
Find Deal
Thu, Jan 15 - Wed, Jan 21
Air Canada Logo
6:00 am - 7:00 amCHS-SCL
23h 00m2 stops
Air Canada Logo
8:55 pm - 2:48 pmSCL-CHS
19h 53m2 stops
$1,808Air Canada
Find Deal

Everything you should know

Top airlines
LATAM Airlines
Cheapest • from $684 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 35% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$684
Typical prices: $729-836
LATAM Airlines
Wed 10/29Tue 11/4
CHS - SCL • 1 stop
Cheapest one-way
Multiple Airlines
Wed 9/10
CHS - SCL • multi-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Booking Insights

KAYAK's insights & trends for Charleston to Santiago flights

Get data-powered insights and trends into flights from Charleston to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Charleston to Santiago?

What’s the cheapest day of the week to fly from Charleston to Santiago?

The average price of all round-trip flights from Charleston to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Charleston to Santiago, you should consider leaving on a Thursday and avoid Tuesdays if you are looking for the best rates. For your return to Charleston, you’ll find the best rates on Wednesdays and the most expensive ones on Thursdays.

What is the cheapest month to fly from Charleston to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Santiago is September, where tickets cost $567 (return) on average. On the other hand, the most expensive months are July and December, where the average cost of round-trip tickets is $1,768 and $1,089 respectively.

Good to know

Low seasonAugust
Cheapest flight$684
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Charleston to Santiago

When to book flights from Charleston to Santiago

Are your dates flexible? Find out the best times to travel from Charleston to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Santiago

  • What is the cheapest flight from Charleston to Santiago?

    In the last 3 days, the lowest price for a flight from Charleston to Santiago was $684 for a round-trip ticket.

  • Do I need a passport to fly between Charleston and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Charleston.

  • Which airports will I be using when flying from Charleston to Santiago?

    When flying out of Charleston you will be using Charleston. You will be landing at Santiago, also known as Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Charleston to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Santiago?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Charleston and Santiago, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Charleston to Santiago, Delta or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Charleston to Santiago are Delta and LATAM Airlines. With an average price for the route of $852 and an overall rating of 7.9, Delta is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $902 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Charleston to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Charleston with another airline. Booking your flights between Charleston and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Charleston to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7963 reviews
8.2Boarding
7.9Entertainment
7.3Food
8.5Crew
7.9Comfort
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

The food was terrible especially for a 15 hour international flight. The crew was unpleasant as well.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Everything you need to know for your flight from Charleston to Santiago

Information on your arrival and departure airports

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