ORD - GSP

$79 Find Cheap Flights from Chicago O'Hare Airport to Greenville - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to Greenville departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$272
Typical prices: $269-$441
Multiple Airlines
Thu 8/20Mon 8/24
ORD - GSP • 2 stops
Cheapest non-stop
$278
Typical prices: $239-$430
American Airlines
Tue 9/22Thu 9/24
ORD - GSP • Non-stop
Top airlines
Cheapest • from $278 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Nonstop flights
You can fly direct with American Airlines and United Airlines. Average duration is 2h 05m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top layover airports
Cheapest • Avg $190 (round-trip)
Shortest trip • 4h 41m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 25% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 20% price drop
Most popular
Good to know
Good to know
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We hope you love your trip to Greenville!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from O'Hare Intl to Greenville (ORD-GSP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to Greenville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to Greenville

Thu, Aug 20 - Mon, Aug 24
Multiple Airlines Logo
8:05 am - 7:39 pm
ORD
-
GSP
10h 34m
2 stops
Multiple Airlines Logo
8:45 pm - 11:08 pm
GSP
-
ORD
27h 23m
1 stop
$272Multiple Airlines
Wed, Sep 9 - Fri, Sep 11
Multiple Airlines Logo
7:11 am - 7:44 pm
ORD
-
GSP
11h 33m
2 stops
Multiple Airlines Logo
1:30 pm - 10:59 pm
GSP
-
ORD
10h 29m
1 stop
$273Multiple Airlines
Tue, Sep 22 - Thu, Sep 24
American Airlines Logo
6:49 pm - 9:54 pm
ORD
-
GSP
2h 05mnonstop
American Airlines Logo
11:33 am - 12:45 pm
GSP
-
ORD
2h 12mnonstop
$278American Airlines
Wed, Oct 14 - Sat, Oct 17
American Airlines Logo
8:09 am - 11:08 am
ORD
-
GSP
1h 59mnonstop
American Airlines Logo
6:43 pm - 8:13 pm
GSP
-
ORD
2h 30mnonstop
$279American Airlines
Sat, Oct 3 - Wed, Oct 7
United Airlines Logo
1:55 pm - 5:05 pm
ORD
-
GSP
2h 10mnonstop
United Airlines Logo
2:16 pm - 3:33 pm
GSP
-
ORD
2h 17mnonstop
$279United Airlines
Mon, Aug 31 - Thu, Sep 3
United Airlines Logo
10:25 am - 1:32 pm
ORD
-
GSP
2h 07mnonstop
United Airlines Logo
10:33 am - 11:53 am
GSP
-
ORD
2h 20mnonstop
$279United Airlines
Fri, Oct 23 - Mon, Oct 26
American Airlines Logo
3:06 pm - 6:08 pm
ORD
-
GSP
2h 02mnonstop
American Airlines Logo
6:43 pm - 8:13 pm
GSP
-
ORD
2h 30mnonstop
$279American Airlines
Fri, Oct 16 - Mon, Oct 19
United Airlines Logo
6:55 am - 9:58 am
ORD
-
GSP
2h 03mnonstop
United Airlines Logo
6:20 am - 7:29 am
GSP
-
ORD
2h 09mnonstop
$279United Airlines
Thu, Aug 27 - Sun, Aug 30
Multiple Airlines Logo
8:05 am - 7:39 pm
ORD
-
GSP
10h 34m
2 stops
Multiple Airlines Logo
8:37 am - 12:50 pm
GSP
-
ORD
29h 13m
1 stop
$279Multiple Airlines
Fri, Sep 18 - Mon, Sep 21
Multiple Airlines Logo
7:11 am - 5:23 pm
ORD
-
GSP
9h 12m
2 stops
Multiple Airlines Logo
12:11 pm - 3:20 pm
GSP
-
ORD
28h 09m
1 stop
$279Multiple Airlines
Booking Insights

KAYAK's insights & trends for O'Hare Intl to Greenville flights

Get data-powered insights and trends into flights from O'Hare Intl to Greenville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago O'Hare Intl Airport to Greenville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago O'Hare Intl Airport to Greenville departing in August.

Flight prices are typical for this route right now.

Flights to Greenville from Chicago O'Hare Intl Airport usually cost between $269 and $441 in August.
The lowest price found in the past 5 days was $272 on Multiple Airlines (Aug 20-Aug 24).

What’s the cheapest day of the week to fly from Chicago O'Hare Airport to Greenville?

The average price of all round-trip flights from Chicago O'Hare Intl Airport to Greenville clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Greenville on a Saturday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Chicago O'Hare Airport to Greenville. For your return ticket, we recommend flying on a Thursday and avoiding Sundays for the best deals.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to Greenville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to Greenville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to Greenville is January, where tickets cost $249 (return) on average. On the other hand, the most expensive months are April and October, where the average cost of round-trip tickets is $365 and $349 respectively.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to Greenville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $309, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Greenville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to Greenville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to Greenville, you should book around 3 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Expert advice

Expert advice for your flight from O'Hare Intl to Greenville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on American Airlines

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Good to know

Low season

September

Cheapest flight

$79
Best time to beat the crowds with an average 8% drop in price.
Flight from Chicago O'Hare Airport to Greenville

When to book flights from O'Hare Intl to Greenville

Are your dates flexible? Find out the best times to travel from O'Hare Intl to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Chicago O'Hare Airport to Greenville flights

  • What is the cheapest flight from Chicago O'Hare Intl Airport to Greenville?

    In the last 5 days, the lowest price for a flight from Chicago O'Hare Intl Airport to Greenville was $79 for a one-way ticket and $272 for a round-trip.

  • Do I need a passport to fly between Chicago O'Hare Airport and Greenville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Chicago O'Hare Airport to Greenville?

    Chicago O'Hare Airport and Greenville are both served by 1 main airport. You will leave Chicago O'Hare Airport from Chicago O'Hare Intl and will be arriving at Greenville.

  • Which airlines offer Wi-Fi service onboard planes from Chicago O'Hare Airport to Greenville?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the Chicago O'Hare Airport to Greenville flight route.

  • Which aircraft models fly most regularly from Chicago O'Hare Airport to Greenville?

    The Embraer 175 (Enhanced Winglets) is the aircraft model that flies most regularly on the Chicago O'Hare Airport to Greenville flight route.

  • Which airline alliances offer flights from Chicago O'Hare Airport to Greenville?

    Star Alliance, and oneworld are the airline alliances operating flights between Chicago O'Hare Airport and Greenville, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Chicago O'Hare Airport to Greenville?

    There are nonstop flights from Chicago O'Hare Airport to Greenville on a daily basis.

  • Which is the best airline for flights from Chicago to Greenville, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Greenville are United Airlines and American Airlines. With an average price for the route of $318 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $301 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to Greenville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to Greenville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to Greenville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Greenville from Chicago O'Hare Airport is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to Greenville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Greenville with an airline and back to Chicago O'Hare Airport with another airline. Booking your flights between Chicago O'Hare Airport and GSP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to Greenville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Greenville from Chicago O'Hare Airport up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Chicago O'Hare Intl Airport to Greenville

  • Looking for a cheap flight? 25% of our users found flights on this route for $253 or less one-way and $269 or less round-trip.

Prefer to fly direct from Chicago O'Hare Airport to Greenville?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Chicago O'Hare Intl to Greenville.
Find which airlines fly direct from Chicago O'Hare Intl Airport to Greenville Airport, which days they fly and book direct flights.

Direct departures

Chicago O'Hare Intl to Greenville

Monday

American Airlines,United Airlines

American Airlines,United Airlines

Tuesday

American Airlines,United Airlines

American Airlines,United Airlines

Wednesday

American Airlines,United Airlines

American Airlines,United Airlines

Thursday

American Airlines,United Airlines

American Airlines,United Airlines

Friday

American Airlines,United Airlines

American Airlines,United Airlines

Saturday

American Airlines,United Airlines

American Airlines,United Airlines

Sunday

American Airlines,United Airlines

American Airlines,United Airlines

See more direct flights

Direct returns

Greenville to Chicago O'Hare Intl

Monday

American Airlines,United Airlines

American Airlines,United Airlines

Tuesday

American Airlines,United Airlines

American Airlines,United Airlines

Wednesday

American Airlines,United Airlines

American Airlines,United Airlines

Thursday

American Airlines,United Airlines

American Airlines,United Airlines

Friday

American Airlines,United Airlines

American Airlines,United Airlines

Saturday

American Airlines,United Airlines

American Airlines,United Airlines

Sunday

American Airlines,United Airlines

American Airlines,United Airlines

See more direct flights

Reviews of the top 3 airlines serving from O'Hare Intl to Greenville

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Greenville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from O'Hare Intl to Greenville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8497 reviews
7.2Food
7.8Entertainment
7.8Comfort
8.1Boarding
8.5Crew
Airline reviews

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

6.0 GoodRafiq, May 2026
ATL - GSP
Read more Delta reviews

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

Very easy to use and convenient, you can perform any action within the same portal

Okay considering we had weather delays which the Pilot notified us of immediately!

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

Stop changing gates. Stop cancelling flights Stop moving my seat.

The staff was frielndly. The plane was terrible, it was too small and should be decommissioned. There were no back seat screens at all. The only beverages we had a choice from was coffee, tea or water. The only bathroom in the back was behind the flight attendant's jump seat and wasn't working. And I literally felt like I was sitting on top of the guy next to me. It was terribly hot in the plane and we had to sit on the tarmac in Chicago for 1/2 hour due to congestion in Mpls. Wouldn't they have know that before they even boarded us so that we could have sat in comfort in the terminal?

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

It was very cold because the air conditioner was on high power, and my son got sick.

The boarding process was terrible especially with an indirect flight Chicago to Seattle to San Diego was terrible talking about we overbooked a flight idk if I’d take this airline ever again we got off our flight from Chicago to Seattle and we traveled for business and they told us our connecting flight was over booked and their was no seats asking people to take a delayed next flight and they don’t tell anyone coughing to wear masks seats 30A-B were terrible during the flight no one wants to sit next to people coughing all around I don’t want to be sick traveling for work or get sick anytime it’s very upsetting the staff doesn’t take this stuff serious to tell them to wear masks when they see people coughing and sneezing

Delta airlines charge $ 30,oo US DOLLARS for the check in for a suitcase in the baggage hold

It was hot and not as comfortable as the flight to Chicago. Must have been a different plane that needs to be worked on or replaced.

The SFO lounge closes at 12 midnight. My flight took off at 2AM

It was extremely hot in the cabin the entire flight, vent air was worn

Have not had a flight out or returning to Norfolk that has not required maintenance, and a gate delay. Properly staff the crew so maintenance can be performed without last minute emergencies on each flight and there is enough staff to have gates prepared for inbound flights. Staff to ensure the safety and on time service vs. profit.

My original flight was cancelled and that affected my trip and my plans and I got no compensation and customer service was hard to reach as well

The flight was delayed by a hour and I wish they had communicated it sooner. No issues on the plane, it did take a while for food to come.

Know that the movies that you are going to be offered are the oldest be rated movies they could possibly get. They may have one or two new movies that they keep advertising but when you’re flying 15 hours, there is nothing to see past the first new movie.

Great experience. Boarding was fast, staff were very nice and funny, everything at the seat worked well.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

Awful. No counter attendants. No dinner offered due to delays.

I had my flight of Cedar Rapids. THen Chicago to Boston. Flight out of Cedar rapids was delayed by 12 hrs. Had to drive to Chicago to catch my flight

Long delays to board due to mechanical issues with plane.

Flight was delayed, boarded, sat at the gate for more than 30 minutes, left the gate then waited on the pad for another 30 to 60 minutes then returned to the gate, deboarded and was cancelled... alternative flight was not booked automatically. Waited in line for 30 minutes but fortunately an alternate flight to a different destination was found ... no thanks to the travel agent used by kayak

The flight from Milwaukee to Dallas was great the staff absolutely amazing. After that EVERYTHING WENT DOWN HILL!!! ABSOLUTELY HORRIBLE!!! WILL NOT FLY THIS AIRLINE AGAIN

I was very unhappy with the lack of communication from the cockpit. It took close to a half an hour before we took off after the doors were closed, and we got no announcements as to progress. It would be nice to get some acknowledgement of the situation and updates as to when we are taking off.

The seat was not even cleaned. It has full of cookie crums probably from last flight's passenger. Its basic expectation that, seats are clean.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The flight was delayed significantly. Communication during the flight was abrupt and caused some panic as we were navigating turbulence. It was also too loud and every announcement felt startling. The flight attendants did not offer any assurances and I felt unsettled most of the flight. The seats, floor and tray table was very dirty. The seat next to me was broken and the passenger sitting there was very uncomfortable. He had a spring in his back and his seat made terrible squeaking noises through the flight.

Significant delays on my trip to Chicago and my trip back to NY

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

Everything you need to know for your flight from O'Hare Intl to Greenville

Information on your arrival and departure airports