$81 Find Cheap Flights from Chicago O'Hare Airport to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to South Carolina departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from O'Hare Intl to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$267
Myrtle Beach
Myrtle Beachnonstop$258
Greenville
Greenville1 stop$227
Columbia
Columbianonstop$269
Florence
Florence1 stop$279
Charlotte
Charlotte1 stop$230
Charleston
Charleston1 stop$267
Myrtle Beach
Myrtle Beachnonstop$258
Greenville
Greenville1 stop$227
Columbia
Columbianonstop$269
Florence
Florence1 stop$279
Charlotte
Charlotte1 stop$230

Book Cheap O'Hare Intl to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to South Carolina

Fri, Aug 7 - Mon, Aug 10
Multiple Airlines Logo
8:05 am - 4:07 pm
ORD
-
GSP
7h 02m
1 stop
Multiple Airlines Logo
4:57 pm - 12:15 pm
GSP
-
ORD
20h 18m
1 stop
$227Multiple Airlines
Tue, Jul 14 - Wed, Jul 22
Frontier Logo
8:05 am - 9:07 pm
ORD
-
CLT
12h 02m
1 stop
Frontier Logo
5:57 pm - 12:49 am
CLT
-
ORD
7h 52m
1 stop
$230Frontier
Wed, Jul 1 - Wed, Jul 8
Frontier Logo
4:59 pm - 4:30 pm
ORD
-
CLT
22h 31m
1 stop
Frontier Logo
8:28 pm - 11:27 pm
CLT
-
ORD
27h 59m
1 stop
$231Frontier
Wed, Jul 1 - Wed, Jul 8
Frontier Logo
4:59 pm - 11:34 am
ORD
-
CLT
17h 35m
1 stop
Frontier Logo
5:57 pm - 12:49 am
CLT
-
ORD
7h 52m
1 stop
$232Frontier
Sat, Sep 26 - Sat, Sep 26
American Airlines Logo
8:26 am - 1:53 pm
ORD
-
CLT
4h 27m
1 stop
American Airlines Logo
4:18 pm - 5:38 pm
CLT
-
ORD
2h 20mnonstop
$241American Airlines
Sat, Sep 12 - Mon, Sep 14
Delta Logo
8:55 am - 3:47 pm
ORD
-
CLT
5h 52m
1 stop
Delta Logo
7:39 pm - 11:59 pm
CLT
-
ORD
5h 20m
1 stop
$246Delta
Tue, Aug 11 - Mon, Aug 17
American Airlines Logo
8:15 am - 11:34 am
ORD
-
MYR
2h 19mnonstop
American Airlines Logo
5:15 pm - 9:57 pm
MYR
-
ORD
5h 42m
1 stop
$258American Airlines
Wed, Jul 8 - Tue, Jul 14
United Airlines Logo
11:00 am - 2:19 pm
ORD
-
MYR
2h 19mnonstop
United Airlines Logo
3:15 pm - 4:49 pm
MYR
-
ORD
2h 34mnonstop
$264United Airlines
Tue, Aug 11 - Mon, Aug 17
Delta Logo
3:31 pm - 11:30 pm
ORD
-
MYR
6h 59m
1 stop
Delta Logo
7:02 pm - 12:02 am
MYR
-
ORD
6h 00m
1 stop
$268Delta
Wed, Jul 8 - Tue, Jul 14
United Airlines Logo
11:00 am - 2:19 pm
ORD
-
MYR
2h 19mnonstop
United Airlines Logo
10:34 am - 4:52 pm
MYR
-
ORD
7h 18m
1 stop
$273United Airlines
Booking Insights

KAYAK's insights & trends for O'Hare Intl to South Carolina flights

Get data-powered insights and trends into flights from O'Hare Intl to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago O'Hare Intl Airport to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago O'Hare Intl Airport to South Carolina departing in July.

What is the cheapest Chicago O'Hare Intl Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago O'Hare Intl Airport found in the last 5 days was to Myrtle Beach, at $254 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 5 days was $265.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago O'Hare Intl Airport to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $369 on average. Morning departures are around 1% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $378.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $370, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to South Carolina is August, when tickets cost $48 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $180 and $179 respectively.

What’s the cheapest day of the week to fly from Chicago O'Hare Airport to South Carolina?

The average price of all round-trip flights from Chicago O'Hare Intl Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Chicago O'Hare Airport to South Carolina, look for departures on Mondays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from South Carolina, Friday is the cheapest day to fly and Monday is the most expensive.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to South Carolina, you should book around 4 weeks before departure, which saves you about 57% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$81
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Chicago O'Hare Airport to Savannah

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago O'Hare Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago O'Hare Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago O'Hare Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from O'Hare Intl to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from O'Hare Intl to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8401 reviews
8.1Boarding
7.8Comfort
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

Definitely a southern flavor. Cordiality was evident even though no drinks or snacks were served.

8.0 ExcellentAnonymous, Jun 2026
ATL - GNV
Read more Delta reviews

Definitely a southern flavor. Cordiality was evident even though no drinks or snacks were served.

On time! There were plenty of airport employees who were able to keep us moving in the right direction. The crew on the plane were professional.

Left /arrived on time. Decent seat space. Like the wifi/plugs and entertainment. Windows and tray table were kinda gross. Attendants didn't start snack service til 40mins before landing. Two rows before us, captain came on to say there's turbulence and recalled staff to seats. So, no drink/snack. Later, attendants didn't stop to see if we had trash nor even look our way. Felt invisible! Almost all pilot announcements were not only unintelligible, but so quiet. We had no idea what she said.

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

Gate agent was unhelpful for handicapped boarding. Flight attendant seemed untrained.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

No meal service to the back of the plane as it started late or was too slow to get it out before it was time to land.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Original flight was on time, then late, then changed gates...4 times. Once our newest plane came in, it was fine.

I almost missed my flight and they helped me out enormously

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Moved to earlier flight which unexpectedly had maintenance issues initially indicated as quick fix to ultimately plane changes. Moved back to original flight, also delayed. In all cases customer updates and communication very unclear, no updates on drivers for delays.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

Pretty awful. 2 hours late due to operational issues and finally deboarded around 2am.

The gate got changed several times and the flight was delayed over an hour. Awful experience

American continues to decline in their customer service and its beyond disappointing.

Everything you need to know for your flight from O'Hare Intl to South Carolina

Information on your arrival and departure airports