$96 Find Cheap Flights from Chicago O'Hare Airport to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to South Carolina departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to South Carolina, as well as popular online travel agencies
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Cheap Flights from O'Hare Intl to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$277
Myrtle Beach
Myrtle Beach2 stops$260
Greenville
Greenvillenonstop$269
Columbia
Columbianonstop$269
Florence
Florence1 stop$379
Charlotte
Charlottenonstop$259
Charleston
Charleston1 stop$277
Myrtle Beach
Myrtle Beach2 stops$260
Greenville
Greenvillenonstop$269
Columbia
Columbianonstop$269
Florence
Florence1 stop$379
Charlotte
Charlottenonstop$259

Book Cheap O'Hare Intl to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to South Carolina

Thu, Aug 13 - Tue, Aug 18
American Airlines Logo
8:10 am - 11:32 am
ORD
-
SAV
2h 22mnonstop
American Airlines Logo
12:02 pm - 1:38 pm
SAV
-
ORD
2h 36mnonstop
$258American Airlines
Sat, Aug 8 - Mon, Aug 10
American Airlines Logo
4:53 pm - 8:04 pm
ORD
-
CLT
2h 11mnonstop
American Airlines Logo
9:35 am - 10:51 am
CLT
-
ORD
2h 16mnonstop
$259American Airlines
Fri, Jul 17 - Tue, Jul 21
Frontier Logo
1:50 pm - 6:03 pm
ORD
-
CLT
27h 13m
2 stops
Frontier Logo
6:41 pm - 12:15 pm
CLT
-
ORD
18h 34m
1 stop
$260Frontier
Tue, Aug 4 - Tue, Aug 11
Multiple Airlines Logo
8:05 am - 11:39 am
ORD
-
MYR
26h 34m
2 stops
Multiple Airlines Logo
3:53 pm - 12:15 pm
MYR
-
ORD
21h 22m
1 stop
$260Multiple Airlines
Wed, Aug 5 - Wed, Aug 12
United Airlines Logo
11:00 am - 2:19 pm
ORD
-
MYR
2h 19mnonstop
United Airlines Logo
6:21 pm - 7:56 pm
MYR
-
ORD
2h 35mnonstop
$261United Airlines
Sat, Aug 8 - Mon, Aug 10
Frontier Logo
7:05 am - 9:13 pm
ORD
-
CLT
13h 08m
2 stops
Frontier Logo
6:41 pm - 12:15 pm
CLT
-
ORD
18h 34m
1 stop
$261Frontier
Wed, Jul 29 - Wed, Aug 5
United Airlines Logo
11:00 am - 2:19 pm
ORD
-
MYR
2h 19mnonstop
United Airlines Logo
10:34 am - 2:29 pm
MYR
-
ORD
4h 55m
1 stop
$262United Airlines
Tue, Jul 14 - Mon, Jul 20
Multiple Airlines Logo
8:05 am - 11:39 am
ORD
-
MYR
26h 34m
2 stops
Multiple Airlines Logo
3:31 pm - 12:15 pm
MYR
-
ORD
21h 44m
1 stop
$263Multiple Airlines
Sat, Aug 22 - Sat, Aug 29
Delta Logo
7:00 am - 12:17 pm
ORD
-
CLT
4h 17m
1 stop
Delta Logo
1:17 pm - 4:17 pm
CLT
-
ORD
4h 00m
1 stop
$267Delta
Thu, Aug 13 - Sat, Aug 15
Delta Logo
8:48 am - 5:30 pm
ORD
-
SAV
7h 42m
1 stop
Delta Logo
6:00 am - 9:40 am
SAV
-
ORD
4h 40m
1 stop
$278Delta
Booking Insights

KAYAK's insights & trends for O'Hare Intl to South Carolina flights

Get data-powered insights and trends into flights from O'Hare Intl to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Chicago O'Hare Intl Airport to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Chicago O'Hare Intl Airport to South Carolina departing in August.

What is the cheapest Chicago O'Hare Intl Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Chicago O'Hare Intl Airport found in the last 5 days was to Myrtle Beach, at $219 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 5 days was $257.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Chicago O'Hare Intl Airport to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $370 on average. Morning departures are around 2% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $382.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $344, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to South Carolina is July, when tickets cost $47 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $180 and $179 respectively.

What’s the cheapest day of the week to fly from Chicago O'Hare Airport to South Carolina?

The average price of all round-trip flights from Chicago O'Hare Intl Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Chicago O'Hare Airport to South Carolina, look for departures on Tuesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from South Carolina, Friday is the cheapest day to fly and Monday is the most expensive.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to South Carolina, you should book around 4 weeks before departure, which saves you about 56% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 4 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$96
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Chicago O'Hare Airport to Savannah

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago O'Hare Airport to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago O'Hare Airport to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago O'Hare Airport to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from O'Hare Intl to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Chicago to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from O'Hare Intl to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8451 reviews
8.5Crew
7.2Food
7.8Comfort
7.8Entertainment
8.1Boarding
Airline reviews

Very easy to use and convenient, you can perform any action within the same portal

10.0 ExcellentMurat, Apr 2026
ORD - LGA
Read more Delta reviews

Very easy to use and convenient, you can perform any action within the same portal

Okay considering we had weather delays which the Pilot notified us of immediately!

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

Stop changing gates. Stop cancelling flights Stop moving my seat.

The staff was frielndly. The plane was terrible, it was too small and should be decommissioned. There were no back seat screens at all. The only beverages we had a choice from was coffee, tea or water. The only bathroom in the back was behind the flight attendant's jump seat and wasn't working. And I literally felt like I was sitting on top of the guy next to me. It was terribly hot in the plane and we had to sit on the tarmac in Chicago for 1/2 hour due to congestion in Mpls. Wouldn't they have know that before they even boarded us so that we could have sat in comfort in the terminal?

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

It was very cold because the air conditioner was on high power, and my son got sick.

Horrible. Flight ORD to CGH was okay, but Paris was a nightmare. Old planes, delays, involuntary downgrades, broken planes, terrible communication. CGH to CPT was my worst flight ever.

The boarding process was terrible especially with an indirect flight Chicago to Seattle to San Diego was terrible talking about we overbooked a flight idk if I’d take this airline ever again we got off our flight from Chicago to Seattle and we traveled for business and they told us our connecting flight was over booked and their was no seats asking people to take a delayed next flight and they don’t tell anyone coughing to wear masks seats 30A-B were terrible during the flight no one wants to sit next to people coughing all around I don’t want to be sick traveling for work or get sick anytime it’s very upsetting the staff doesn’t take this stuff serious to tell them to wear masks when they see people coughing and sneezing

Delta airlines charge $ 30,oo US DOLLARS for the check in for a suitcase in the baggage hold

Great experience. Boarding was fast, staff were very nice and funny, everything at the seat worked well.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

Awful. No counter attendants. No dinner offered due to delays.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The flight was delayed significantly. Communication during the flight was abrupt and caused some panic as we were navigating turbulence. It was also too loud and every announcement felt startling. The flight attendants did not offer any assurances and I felt unsettled most of the flight. The seats, floor and tray table was very dirty. The seat next to me was broken and the passenger sitting there was very uncomfortable. He had a spring in his back and his seat made terrible squeaking noises through the flight.

Significant delays on my trip to Chicago and my trip back to NY

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

I’ve got 31F seat and window seat . My 2 co passengers was AA crew members and they were very rude attitude and when I was going to use bathroom their gestures was very different and awkward and the guy beside me completely occupied the hand rest and I was really uncomfortable

It was so much better than expected, Ohare is not such a pleasant experience but American Airlines with the new, clean aeroplane and free Wi-Fi was outstanding and the crew so pleasant and helpful.

It wa sort of on time; the cab was left with some trash

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

Everything you need to know for your flight from O'Hare Intl to South Carolina

Information on your arrival and departure airports