$466 Find Cheap Flights from Chicago to Patagonia - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Patagonia departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Chicago to Patagonia

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
El Calafate
El Calafate3 stops$1,201
Ushuaia
Ushuaia2 stops$1,183
Punta Arenas
Punta Arenas3 stops$918
Puerto Montt
Puerto Montt3 stops$913
Balmaceda
Balmaceda3 stops$929
El Calafate
El Calafate3 stops$1,201
Ushuaia
Ushuaia2 stops$1,183
Punta Arenas
Punta Arenas3 stops$918
Puerto Montt
Puerto Montt3 stops$913
Balmaceda
Balmaceda3 stops$929

Book Cheap Chicago to Patagonia Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Patagonia that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Patagonia

Sun, Aug 16 - Sun, Aug 23
Multiple Airlines Logo
8:02 am - 5:09 pm
ORD
-
PUQ
31h 07m
3 stops
Multiple Airlines Logo
6:04 pm - 1:59 pm
PUQ
-
ORD
21h 55m
3 stops
$918Multiple Airlines
Wed, Dec 9 - Thu, Dec 17
Multiple Airlines Logo
7:00 am - 3:37 pm
ORD
-
BBA
29h 37m
3 stops
Multiple Airlines Logo
4:25 pm - 10:07 am
BBA
-
ORD
20h 42m
3 stops
$929Multiple Airlines
Mon, Aug 24 - Mon, Aug 31
Multiple Airlines Logo
5:30 am - 1:17 pm
ORD
-
PUQ
29h 47m
3 stops
Multiple Airlines Logo
6:04 pm - 9:20 pm
PUQ
-
ORD
29h 16m
3 stops
$931Multiple Airlines
Tue, Aug 18 - Tue, Aug 25
Multiple Airlines Logo
6:00 pm - 11:01 am
ORD
-
BBA
64h 01m
3 stops
Multiple Airlines Logo
10:47 am - 9:58 pm
BBA
-
ORD
36h 11m
2 stops
$933Multiple Airlines
Tue, Nov 17 - Thu, Dec 3
LATAM Airlines Logo
1:30 pm - 3:50 pm
ORD
-
BBA
23h 20m
2 stops
LATAM Airlines Logo
4:25 pm - 12:06 pm
BBA
-
ORD
22h 41m
3 stops
$934LATAM Airlines
Wed, Aug 19 - Wed, Aug 26
Multiple Airlines Logo
1:50 pm - 10:00 am
ORD
-
BBA
43h 10m
2 stops
Multiple Airlines Logo
10:47 am - 8:52 am
BBA
-
ORD
47h 05m
2 stops
$935Multiple Airlines
Wed, Dec 9 - Thu, Dec 17
LATAM Airlines Logo
10:40 am - 2:46 pm
ORD
-
BBA
25h 06m
2 stops
LATAM Airlines Logo
10:12 am - 8:34 am
BBA
-
ORD
25h 22m
2 stops
$953LATAM Airlines
Mon, Aug 17 - Mon, Aug 31
Delta Logo
10:07 am - 1:13 pm
ORD
-
PUQ
25h 06m
2 stops
Delta Logo
7:19 pm - 11:57 pm
PUQ
-
ORD
54h 38m
2 stops
$1,006Delta
Sat, Sep 12 - Sat, Sep 19
Avianca Logo
11:20 pm - 7:30 am
ORD
-
FTE
54h 10m
2 stops
Avianca Logo
5:50 pm - 9:20 pm
FTE
-
ORD
53h 30m
2 stops
$1,312Avianca
Sun, Aug 16 - Sun, Aug 23
Avianca Logo
11:20 pm - 10:35 am
ORD
-
USH
33h 15m
2 stops
Avianca Logo
4:50 pm - 9:20 pm
USH
-
ORD
30h 30m
2 stops
$1,323Avianca
Booking Insights

KAYAK's insights & trends for Chicago to Patagonia flights

Get data-powered insights and trends into flights from Chicago to Patagonia to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to Patagonia?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $498, prices are generally cheapest when you fly direct.

Good to know

Cheapest flight$466
Flight from Chicago to Ushuaia

FAQs - booking Patagonia flights

  • How does KAYAK find such low prices on flights from Chicago to Patagonia?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Patagonia.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Patagonia?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago to Patagonia is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Patagonia?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago to Patagonia with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Patagonia?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago to Patagonia up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Chicago to Patagonia

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Patagonia. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Patagonia? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1949 reviews
7.0Entertainment
8.0Crew
6.7Food
7.3Comfort
7.5Boarding
Airline reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

10.0 ExcellentYelen, Mar 2026
ATL - TPA
Read more LATAM Airlines reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Everything you need to know for your flight to Patagonia

Information on your arrival and departure airports