$206 Find Cheap Flights from Columbus to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Columbus to South America departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Columbus to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$594
Bogotá
Bogotá1 stop$595
Buenos Aires
Buenos Aires2 stops$1,002
Sao Paulo
Sao Paulo1 stop$750
Rio de Janeiro
Rio de Janeiro2 stops$761
Santiago
Santiago1 stop$887
Cartagena
Cartagena2 stops$577
Quito
Quito1 stop$689
Guayaquil
Guayaquil1 stop$710
Cali
Cali2 stops$665
Cusco
Cusco3 stops$1,007
Georgetown
Georgetown2 stops$775
Asuncion
Asuncion2 stops$1,253
Lima
Lima2 stops$594
Bogotá
Bogotá1 stop$595
Buenos Aires
Buenos Aires2 stops$1,002
Sao Paulo
Sao Paulo1 stop$750
Rio de Janeiro
Rio de Janeiro2 stops$761
Santiago
Santiago1 stop$887
Cartagena
Cartagena2 stops$577
Quito
Quito1 stop$689
Guayaquil
Guayaquil1 stop$710
Cali
Cali2 stops$665
Cusco
Cusco3 stops$1,007
Georgetown
Georgetown2 stops$775
Asuncion
Asuncion2 stops$1,253

Book Cheap Columbus to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Columbus to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Columbus to South America

Sat, Jul 18 - Tue, Jul 28
American Airlines Logo
5:40 pm - 12:35 pm
CMH
-
CTG
19h 55m
2 stops
American Airlines Logo
3:17 pm - 11:40 am
CTG
-
CMH
19h 23m
2 stops
$577American Airlines
Sat, Jul 18 - Tue, Jul 28
American Airlines Logo
6:19 pm - 2:17 pm
CMH
-
CTG
20h 58m
1 stop
American Airlines Logo
3:17 pm - 11:40 am
CTG
-
CMH
19h 23m
2 stops
$589American Airlines
Tue, Aug 4 - Thu, Aug 13
Delta Logo
6:00 am - 7:15 pm
CMH
-
BOG
14h 15m
1 stop
Delta Logo
8:40 am - 12:58 am
BOG
-
CMH
15h 18m
2 stops
$595Delta
Wed, Sep 30 - Sat, Oct 24
Delta Logo
3:50 pm - 1:15 pm
CMH
-
CTG
22h 25m
1 stop
Delta Logo
5:30 am - 6:45 pm
CTG
-
CMH
12h 15m
2 stops
$600Delta
Mon, Aug 3 - Wed, Aug 12
LATAM Airlines Logo
10:02 am - 7:15 pm
CMH
-
BOG
10h 13m
1 stop
LATAM Airlines Logo
2:55 pm - 12:58 am
BOG
-
CMH
9h 03m
1 stop
$604LATAM Airlines
Mon, Aug 3 - Mon, Aug 10
LATAM Airlines Logo
10:02 am - 7:15 pm
CMH
-
BOG
10h 13m
1 stop
LATAM Airlines Logo
11:00 am - 12:58 am
BOG
-
CMH
12h 58m
2 stops
$608LATAM Airlines
Mon, Oct 26 - Tue, Nov 3
United Airlines Logo
6:45 am - 9:05 pm
CMH
-
MDE
15h 20m
1 stop
United Airlines Logo
10:45 am - 9:50 pm
MDE
-
CMH
11h 05m
1 stop
$609United Airlines
Mon, Oct 26 - Wed, Nov 4
United Airlines Logo
5:40 am - 9:05 pm
CMH
-
MDE
16h 25m
2 stops
United Airlines Logo
10:45 am - 8:38 am
MDE
-
CMH
21h 53m
2 stops
$614United Airlines
Sun, Oct 4 - Tue, Oct 20
Copa Airlines Logo
5:20 am - 11:40 pm
CMH
-
LIM
19h 20m
2 stops
Copa Airlines Logo
4:40 pm - 9:36 am
LIM
-
CMH
15h 56m
2 stops
$782Copa Airlines
Tue, Oct 6 - Fri, Oct 16
Copa Airlines Logo
7:58 pm - 12:51 am
CMH
-
EZE
27h 53m
2 stops
Copa Airlines Logo
12:10 am - 8:45 pm
EZE
-
CMH
21h 35m
2 stops
$1,194Copa Airlines
Booking Insights

KAYAK's insights & trends for Columbus to South America flights

Get data-powered insights and trends into flights from Columbus to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Columbus Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Columbus Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Columbus Airport to South America is October, when tickets cost $225 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $381 and $352 respectively.

How far in advance should I book a flight from Columbus Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Columbus Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Columbus Airport to South America, you should book around 3 weeks before departure, which saves you about 39% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 5 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$206
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Columbus to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Columbus to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Columbus to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Columbus to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Columbus to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Columbus to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Columbus to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Columbus to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Columbus to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Columbus to South America

 
Need help choosing which airline to fly with from Columbus to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8455 reviews
7.2Food
8.5Crew
8.1Boarding
7.8Entertainment
7.8Comfort
Airline reviews

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

10.0 ExcellentBenjamin, May 2026
CLT - MSP
Read more Delta reviews

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

In flight from Miami to Anchorage, we were all on board ready to take off. Pilot decided to take on more fuel causing a delay. Once fueled, the pilot came back over the radio stating more delay due to VIP. These delays caused me to miss my connecting flight. I went to the Alaska Air counter for information. They flat out stated that it was ATCs fault that I missed my flight and booked me a flight the next day about 1300 . I believe if we had the fuel prior to getting on board we would not of been delayed and I would have taken off on time. Pilot was taken out of the equation. I think they should’ve taken responsibility for their pilots decision to top off his aircraft instead of waiting til the last moment. Enough said…

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

No complaints other than luggage carousel was incorrectly guiding passengers to the wrong carousel on the screen.

Did not like that we couldn't complete check in on-line without providing pictures of our passports. Worry about identity theft. We had no delays and boarding was handled In an efficient manner.

We were a little disappointed to not be able to complete check in online without uploading pics of passports. Also we have KTN's and they weren't on our boarding passes when we got to security. Had to trek back to counter to have them fix.

Excellent service in Polaris class IAD to ZRH. Arrived rested and well fed after the overnight flight.

My flight time was changed without any notification to me which ruined my time sensitive plans so I ended up completely changing my travel plans and no reimbursement.

Excellent! I got to Munich and was transferred to my Lufthansa flight quickly, in 15 to 20 minutes, so I did not miss my flight. However, I had checked my overhead bag at the boarding gate in Tampa. That got to Tunis the next day. That is to be expected.

It's a short hop. My carryon was checked at the gate, I didn't have to drag it all over the airport. Excellent wheelchair assist.

WiFi didn’t exist , seats were super cramped, lights stayed on near my seat for a long time while others were dimmed, the food/trash/drink cart hit my shoulder at least a couple of times while moving, food options were down to just one option by the time it got to my row, the utensils were garbage (knife bent at a couple of places by the time I was done eating) the spoon was very flimsy plastic

Friendliest Flight Attendant I’ve seen since I flew on Southwest Airlines. The whole trip was outstanding…and arrived Early!

It was good overall except from Omaha to Denver when flight a was a repeatedly delayed apparently due to some issue at Denver. Communications could have been handled better. I had to board then deboard with luggage and board again

Fine. Nothing to write home about. The plane left on time, and arrived on time.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

Seat comfort was poor (no lumbar or lower back support).

The airplane seats were spacious and comfortable, and the flight attendants were friendly and attentive. The food was delicious like never before. The blankets and toiletries were thoughtfully provided. The captain's navigation was steady and reliable. In short, having flown with Starlux, I won't consider any other airline next time.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

It would have been better IF IT HAD NOT BEEN CANCELED!!!!

There was no flight. Spirit went bankrupt Right before my departure and kayak did not refund me any money. I would like my refund kayak. How can I get it? Please let me know. Thank you

Flights were canceled due to airline shutting down and haven’t received a reimbursement. Had to book last minute new flights which were expensive

My flight was canceled the morning of the flight. I had to rebook a flight with a different airline that cost me $900 out of my pocket

Are you serious? I know this is an automated message but how can you not update the system?

Had a flight change had to get a credit.will I get my money back.

Shut down without prior notice End up with spending lots of extra $$$

There was a crack in my window seal. And Spirit is now closed forever.

The company went out of business and now I'm stuck in Ft. Lauderdale. Would not recommend.

Spirit changed flight times by 12 hours with coming and going so I refunded tickets and drove

Everything you need to know for your flight to South America

Information on your arrival and departure airports