$123 Find Cheap Flights from Columbus to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Columbus to South America departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Columbus to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$670
Bogotá
Bogotá1 stop$402
Buenos Aires
Buenos Aires2 stops$1,074
Sao Paulo
Sao Paulo1 stop$890
Rio de Janeiro
Rio de Janeiro2 stops$957
Santiago
Santiago2 stops$800
Cartagena
Cartagena2 stops$362
Quito
Quito2 stops$687
Guayaquil
Guayaquil2 stops$483
Cali
Cali3 stops$543
Cusco
Cusco3 stops$829
Georgetown
Georgetown1 stop$683
Asuncion
Asuncion3 stops$1,197
Lima
Lima1 stop$670
Bogotá
Bogotá1 stop$402
Buenos Aires
Buenos Aires2 stops$1,074
Sao Paulo
Sao Paulo1 stop$890
Rio de Janeiro
Rio de Janeiro2 stops$957
Santiago
Santiago2 stops$800
Cartagena
Cartagena2 stops$362
Quito
Quito2 stops$687
Guayaquil
Guayaquil2 stops$483
Cali
Cali3 stops$543
Cusco
Cusco3 stops$829
Georgetown
Georgetown1 stop$683
Asuncion
Asuncion3 stops$1,197

Book Cheap Columbus to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Columbus to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Columbus to South America

Fri, May 1 - Thu, May 7
Multiple Airlines Logo
6:35 pm - 12:06 pm
CMH
-
CTG
42h 31m
2 stops
Multiple Airlines Logo
1:31 pm - 11:56 pm
CTG
-
CMH
9h 25m
1 stop
$362Multiple Airlines
Fri, May 8 - Sat, May 16
Multiple Airlines Logo
8:48 pm - 1:00 pm
CMH
-
MDE
17h 12m
1 stop
Multiple Airlines Logo
1:55 pm - 5:10 pm
MDE
-
CMH
26h 15m
2 stops
$363Multiple Airlines
Fri, May 15 - Wed, Jun 10
Multiple Airlines Logo
8:48 pm - 1:00 pm
CMH
-
MDE
17h 12m
1 stop
Multiple Airlines Logo
1:55 pm - 5:05 pm
MDE
-
CMH
26h 10m
2 stops
$380Multiple Airlines
Sat, May 9 - Sat, May 16
Spirit Airlines Logo
6:00 am - 1:03 pm
CMH
-
BOG
8h 03m
1 stop
Spirit Airlines Logo
2:08 pm - 12:42 pm
BOG
-
CMH
21h 34m
2 stops
$402Spirit Airlines
Sat, May 9 - Sat, May 16
Spirit Airlines Logo
6:00 am - 12:43 pm
CMH
-
MDE
7h 43m
1 stop
Spirit Airlines Logo
1:55 pm - 12:42 pm
MDE
-
CMH
21h 47m
1 stop
$404Spirit Airlines
Fri, Jul 24 - Sat, Aug 8
American Airlines Logo
4:38 pm - 12:35 pm
CMH
-
CTG
20h 57m
2 stops
American Airlines Logo
3:15 pm - 12:19 pm
CTG
-
CMH
20h 04m
2 stops
$577American Airlines
Tue, May 26 - Tue, Jun 2
American Airlines Logo
7:00 am - 12:35 pm
CMH
-
CTG
6h 35m
1 stop
American Airlines Logo
1:35 pm - 12:45 am
CTG
-
CMH
10h 10m
1 stop
$593American Airlines
Mon, Oct 5 - Tue, Oct 27
LATAM Airlines Logo
7:00 am - 9:35 pm
CMH
-
LIM
15h 35m
2 stops
LATAM Airlines Logo
12:00 pm - 11:55 pm
LIM
-
CMH
10h 55m
1 stop
$699LATAM Airlines
Sun, Oct 4 - Tue, Oct 20
LATAM Airlines Logo
12:05 pm - 6:45 am
CMH
-
LIM
19h 40m
1 stop
LATAM Airlines Logo
1:30 pm - 11:35 am
LIM
-
CMH
21h 05m
2 stops
$719LATAM Airlines
Fri, Jun 12 - Tue, Jun 23
Delta Logo
8:08 pm - 6:59 pm
CMH
-
UIO
23h 51m
1 stop
Delta Logo
6:50 pm - 1:40 pm
UIO
-
CMH
17h 50m
2 stops
$728Delta
Booking Insights

KAYAK's insights & trends for Columbus to South America flights

Get data-powered insights and trends into flights from Columbus to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Columbus Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Columbus Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Columbus Airport to South America is January, when tickets cost $443 (return) on average. On the other hand, the most expensive months are April and June, when the average cost of round-trip tickets is $1,047 and $982 respectively.

How far in advance should I book a flight from Columbus Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Columbus Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Columbus Airport to South America, you should book around 3 weeks before departure, which saves you about 35% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 5 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$123
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 27% increase in price.
Flight from Columbus to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Columbus to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Columbus to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Columbus to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Columbus to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Columbus to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Columbus to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Columbus to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Columbus to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Columbus to South America

 
Need help choosing which airline to fly with from Columbus to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8406 reviews
7.8Entertainment
8.5Crew
8.1Boarding
7.9Comfort
7.2Food
Airline reviews

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

8.0 ExcellentBarbie, Apr 2026
BOS - SFO
Read more Delta reviews

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

Crew was great. Near on time departure and early arrival. Snacks are always meh. Not a fan of the "pay for everything including miles " proposal unless base flight rate going to be 100 bucks.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

Overall Good! The weather delayed our takeoff from Atlanta and our arrival in Miami! If Mother Nature can mess up a flight she will do it every time!

The flight was smooth, the crew was great but the plane was quite old

Everything was great until I lost my water bottle and they can’t seem to locate it. I know I left it on the plane though.

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Okay considering we had weather delays which the Pilot notified us of immediately!

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Packed in plane small uncomfortable seats elbow to elbow nobody wants to be in that situation for the money they paid

Vegetarian selection could be better. Bread was too hard to chew.

Crew was friendly and competent. Food, wine, and entertainment were excellent except the raw tuna on the flight to Split. Recommend against serving that - at least as the only option. Many medical conditions do not allow people to eat raw fish.

Overall flight was ok. Flight attendant was receptive to assisting passengers with tight connections.

Checking in united could not figure out my star alliance gold. Baggage did not get marked priority and didn't receive boarding passes. When got to SFO lounge personal fixed everything Immediately

Very comfortable flight, snacks and drinks were good, good communication from crew. Could have used a little more information on timing of boarding for group 5

It's a long flight and I would have liked better snacks between lunch and the arrival meal. It's fine to have fruit and nuts but I really don't like ramen because it's salty junk soup. I'd suggest sandwiches. They're not expensive nor are they hard to store for a long flight. The FA's had a couple of big services and they were super busy preparing, executing and then cleaning up. Then they disappeared.

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

This was the first flight in the morning. We boarded fine. The cabin door was closed and we were ready to go. We were notified by the Captain that ATC issued and ground stop for 40 minutes. So, without even pushing back from the gate, we were already 40 minutes late. We actually were released to push-back and taxi at 30 minutes. But, some passengers had tight connections and were not going to make their connections. Some passengers asked about the delay and the effect on the connections and were told by the cabin attendant that all flights will be delayed and so they should be OK. However, that was not true. My connecting flight was on time and I arrived at IAH with 21 minutes to make my connection. I did and I'm happy about that, but the flight crew should not have given assurances to the passengers who might have missed their connections.

Friendly crew is the only nice thing. Seats uncomfortable. Food and snacks horrible. Movies were the same as the first 10 hour flight two weeks before

When I booked my flight a month ago - I selected a seat. That seat was NOT the one I ended up with when I checked into my flight the day before. This is the second time this has occurred. So, I checked my next flight on Wednesday and Thursday and no seat was assigned. Poor, very poor customer service.

The staff and service on American Airlines were truly outstanding. I had requested wheelchair assistance for my mother due to her knee issues, and the team went above and beyond every step of the way—from boarding in Boston to our arrival in Chicago. Their care, professionalism, and attentiveness made the entire experience smooth and stress-free. I’m very grateful for the support they provided.

Incredibly delayed. First delay was due to plane coming in being late. Resulted in 30 minute delay. Boarded and then had multiple mechanical issues. Was on plane for an hour until they told people they could get off if they wanted but couldn't come back. Then gate agent rushed in and said they had lost control of who went off and we would all have to deplane and then get back on. They said flight had not been cancelled. Then while sitting waiting to board again they announced it would take two hours to get new plane and to wait at new gate. New plane arrived, reboarded only to find out that pilots had timed out. Waited for new pilots. In that time one of the flight attendants timed out. Never received food or water while waiting. Was confusing mess as to what was happening. Even flight attendants and gate agents were getting frustrated. Almost 6 hours delayed. Called American to received flight credit but can't get anywhere as Kayak reservation and don't have a ticket number. Reached out to Kayak but never heard back.

American flight was diverted and delayed but app didn’t show that information so I wasn’t able to change my connection until the last min.

Wifi was spotty. Tray table was very dirty when I sat down.

Very disappointing. Flight was delayed by 1.5 hours and food options are very underwhelming even for first class seats (same food given to economy seats)

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

The plane was very creaky and lots of ringing. Plane was dirty and dingy. I couldn't hear the captain's announcements from the flight deck. Not sure if it was the captain or the audio equipment, but good thing there wasn't an emergency where we needed clear instructions. The overhead compartments were clearly full, but the flight crew allowed people to stand in the back with their carry on luggage. Then after everyone boarded, they had to go to the front to gate check their luggage because there was no room for their bags and then they returned to their seats...such a waste of time when clearly the overhead compartments were full when they originally boarded.

The new planes (American Eagle) are beautiful and especially comfortable. The flight attendants are consistently professional and courteous. And, while it may seem inconsequential, the new liquid tube of coffee creamer—in contrast to the powdered coffee creamer—makes all the difference in a cup of coffee.

Spirit is awful, and cost me an extra $400. On the flight to the destination they staff was rude and did not even offer water during the flight. On the return flight, while on the way to the terminal, Spirit cancelled the flight. This is the second time this has happened, and I believe they should compensate for the additional cost for incurred for the return flight. Spirit simply offered reimbursement for their cancelled flight, and did not take into consideration the cost for a last-minute flight home. The TSA agents expressed how Spirit often cancels evening/night flights, and shows no concern for the passengers.

The flight was delayed four times and finally cancelled. The hotel night we paid for and the connecting flight did not happen. There were also additional costs due to the extra night in Miami. I do not recommend this airline.

The repeated flight delays—this time nearly three hours without any weather-related cause—are unacceptable. Yet, passengers are penalized heavily even for being a minute late. It is unreasonable that there is no compensation for such significant delays, nor even basic provisions like water during the wait or in flight. This imbalance in accountability is deeply frustrating and needs to be addressed.

My flight with spirit airlines was canceled leaving me stranded until tomorrow.

My flight was delayed then put back on time then cancelled and they automatically rebooked me to another flight but that flight was going to make me late to a concert i had planned for. Flight was at 10am concert was at 7pm from Burbank to Las Vegas so I allowed enough time but the flight that was rebooked was too late so I talked with the desk and they were able to get me on an afternoon flight. Thank goodness. That was stressful for a moment. I want to thank the person who helped me get to my show on time. Concert tickets are very expensive and the show was amazing. Hopefully my flight home will be smooth.

Unfortunately Stuff and the stuff boarded us were so rude to many of passengers.i will never fly Spirit again .

Always Good ,… Spirit customers are high class Delta customers are self proclaimed elites and American crews you can hear them complain about everything (they’re loud)

Very nice. Although, it would be nice to offer a glass of water for free. At least.....

They didn’t put my luggage on my transfer so I had to spend the night in Detroit. They said my luggage would be here in the morning and they’re still searching for it. It did not arrive apparently.

The attendant at the gate was not helpful at all and she was rude when we asked why the flight was delayed.

Everything you need to know for your flight to South America

Information on your arrival and departure airports