$180 Find Cheap Flights from Columbus to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Columbus to South America departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Columbus to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$565
Bogotá
Bogotá2 stops$615
Buenos Aires
Buenos Aires2 stops$952
Sao Paulo
Sao Paulo2 stops$713
Rio de Janeiro
Rio de Janeiro1 stop$722
Santiago
Santiago2 stops$728
Cartagena
Cartagena2 stops$572
Quito
Quito1 stop$706
Guayaquil
Guayaquil2 stops$847
Cali
Cali2 stops$596
Cusco
Cusco3 stops$1,093
Georgetown
Georgetown2 stops$844
Asuncion
Asuncion2 stops$1,175
Lima
Lima2 stops$565
Bogotá
Bogotá2 stops$615
Buenos Aires
Buenos Aires2 stops$952
Sao Paulo
Sao Paulo2 stops$713
Rio de Janeiro
Rio de Janeiro1 stop$722
Santiago
Santiago2 stops$728
Cartagena
Cartagena2 stops$572
Quito
Quito1 stop$706
Guayaquil
Guayaquil2 stops$847
Cali
Cali2 stops$596
Cusco
Cusco3 stops$1,093
Georgetown
Georgetown2 stops$844
Asuncion
Asuncion2 stops$1,175

Book Cheap Columbus to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Columbus to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Columbus to South America

Fri, Nov 6 - Sat, Nov 14
Air Canada Logo
9:30 am - 3:15 am
CMH
-
LIM
17h 45m
2 stops
Air Canada Logo
8:00 am - 9:12 pm
LIM
-
CMH
37h 12m
2 stops
$565Air Canada
Wed, Nov 4 - Sun, Nov 22
Multiple Airlines Logo
9:30 am - 10:45 am
CMH
-
LIM
25h 15m
2 stops
Multiple Airlines Logo
2:55 am - 9:12 pm
LIM
-
CMH
18h 17m
2 stops
$569Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
American Airlines Logo
6:00 am - 2:15 pm
CMH
-
CTG
9h 15m
2 stops
American Airlines Logo
3:15 pm - 12:15 pm
CTG
-
CMH
20h 00m
2 stops
$572American Airlines
Sat, Sep 19 - Fri, Sep 25
Delta Logo
6:00 am - 1:15 pm
CMH
-
CTG
8h 15m
1 stop
Delta Logo
9:20 am - 10:01 am
CTG
-
CMH
23h 41m
2 stops
$610Delta
Sat, Sep 19 - Sat, Sep 26
Delta Logo
6:00 am - 1:15 pm
CMH
-
CTG
8h 15m
1 stop
Delta Logo
2:30 pm - 12:02 pm
CTG
-
CMH
20h 32m
1 stop
$616Delta
Tue, Sep 8 - Tue, Sep 15
United Airlines Logo
6:30 am - 9:10 pm
CMH
-
MDE
15h 40m
1 stop
United Airlines Logo
9:45 am - 11:44 pm
MDE
-
CMH
12h 59m
1 stop
$619United Airlines
Tue, Sep 22 - Tue, Sep 29
United Airlines Logo
5:20 am - 9:10 pm
CMH
-
MDE
16h 50m
2 stops
United Airlines Logo
9:45 am - 11:44 pm
MDE
-
CMH
12h 59m
1 stop
$624United Airlines
Thu, Aug 13 - Mon, Aug 17
American Airlines Logo
6:16 am - 12:35 pm
CMH
-
CTG
7h 19m
1 stop
American Airlines Logo
3:15 pm - 12:15 pm
CTG
-
CMH
20h 00m
2 stops
$626American Airlines
Sun, Oct 4 - Tue, Oct 20
LATAM Airlines Logo
6:20 pm - 6:45 am
CMH
-
LIM
13h 25m
1 stop
LATAM Airlines Logo
12:05 pm - 12:10 am
LIM
-
CMH
11h 05m
1 stop
$731LATAM Airlines
Tue, Dec 1 - Mon, Dec 7
LATAM Airlines Logo
2:30 pm - 9:00 pm
CMH
-
LIM
30h 30m
1 stop
LATAM Airlines Logo
12:05 am - 1:41 pm
LIM
-
CMH
13h 36m
1 stop
$739LATAM Airlines
Booking Insights

KAYAK's insights & trends for Columbus to South America flights

Get data-powered insights and trends into flights from Columbus to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Columbus Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Columbus Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Columbus Airport to South America is February, when tickets cost $243 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $502 and $352 respectively.

How far in advance should I book a flight from Columbus Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Columbus Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Columbus Airport to South America, you should book around 3 weeks before departure, which saves you about 35% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$180
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Columbus to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Columbus to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Columbus to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Columbus to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Columbus to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Columbus to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Columbus to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Columbus to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Columbus to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Columbus to South America

 
Need help choosing which airline to fly with from Columbus to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8456 reviews
7.8Comfort
7.8Entertainment
8.1Boarding
7.2Food
8.5Crew
Airline reviews

Didn't like sitting on the waiting pad for 30 minutes right after departing the gate. If you're going to do that, just don't board so people can still get up and walk around in the terminal. My luggage was damaged by the baggage handlers.

4.0 OkayJeffrey, Apr 2026
CMH - DTW
Read more Delta reviews

Didn't like sitting on the waiting pad for 30 minutes right after departing the gate. If you're going to do that, just don't board so people can still get up and walk around in the terminal. My luggage was damaged by the baggage handlers.

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Good flight. Connector flight was delayed so made a short turnaround in Atlanta which was stressful. Otherwise, great crew, Staff in ATL was very informative about the delay and ensured people their connections were fine. Notified the ones that were not. Great communication.

Seat was extremely hard which made even a short 1 hour 20 minute flight fairly uncomfortable.

Only water, tea or coffee served midflight, even to comfort seating. Man next to me needed two seats and took up a portion of my seat and Delta did nothing.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

I like for how they process during check in. It was very smoothly.

Boarding was somewhat chaotic. Unable to evaluate crew or food/drink because captain kept them seated due to turbulence. Have no idea if entertainment was offered.

I liked the piloting of the aircraft. Very disappointed about lack of electrical ports. Also, although a short flight. there was enough time to hand out snacks to comfort + seats as was done for first class.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was good, plane is a bit older so seats are somewhat flat

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

The entertainment options on the seat back video boards were nice.

There was no WiFi available, there were mechanical problems with the plane and we landed at C 124, then the gate was switched to A 26, then all the way back to C126! For a 75 yo woman traveling alone, this was a difficult journey, indeed!

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Very bad! They kept delaying my flight and wouldn’t do anything about it

IAD with the archaic people movers is just a place to be avoided.

Cabin was pitch black, even during meal service. The reading lights for seat 2E/F did not work, and seat 2E did not recline.

The flight from Cleveland to Newark was great. The connecting flight wasn’t so good.

Check in and boarding were very easy. Quite good food and a complimentary glass of wine with dinner. The acoustics on the TV difficult at times, and the options extensive though not very updated.

Flight was not comfortable and crew was rude and not wanted to help, i would never choose united if there is alternate options . not cooperative with baby

Crew did not arrive for their shift and flight delayed for 2 1/2 hours whilst new pilots were found. The man at the boarding gate did a great job keeping us informed and the eventual flight was good. It was just the long delay waiting…….

Flights on time w/o delays. However, my baggage was damaged. Ground crew, throws baggage from plane to the baggage carrier, carelessly.

On time flight, good communication about boarding, lines didn't form unnecessarily for boarding before their group was announced (kept aisles clear), friendly flight attendants and service

They put me on an earlier and I got home sooner

I love American. I’ll never fly anyone else if I can help it.

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

The flight was fine and the crew awesome. The problem is ORD and AA. Computers went down, ORD fell apart and a 40 min flight turned into a 3 hour trip. Guess the answer is to not try and fly to ORD after noon. But, as I said, crew was awesome and did everything they could to lesson the flight time.

Boarded over an hour late, no communication, the sign just changed, no attendant to answer questions - she disappeared forever (hiding). Small plane and couldn’t hear the overhead nor understand.

Was supposedly in main extra (row 10), but the seat spacing appeared to be regular economy (the head rest was blue, as well - same as economy, the seats in front of us had red head rests). Otherwise the flight was good and got in well ahead of schedule.

Flight was scheduled to leave at 6:25am. Went to bed at 9pm to get enough sleep. Flight cancelled at 1am that morning. Only flights available either landed at 8:30pm (9 hours later and 3 hours after the event I was trying to attend) or in a completely different state. Way to screw up my weekend, American.

Everything you need to know for your flight to South America

Information on your arrival and departure airports