DEN - SCL

$355 Find Cheap Flights from Denver to Santiago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Santiago departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$581
Typical prices: $608-$895
Copa Airlines
Sun 11/8Wed 11/18
DEN - SCL • 1 stop
Cheapest one-way
$355
Typical prices: $406-$623
Multiple Airlines
Sat 8/8
DEN - SCL • 3 stops
Top airlines
Cheapest • from $581 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Denver and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $750 (round-trip)
Shortest trip • 14h 47m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 15% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Denver to Santiago (DEN-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Santiago

Sun, Nov 8 - Wed, Nov 18
Copa Airlines Logo
9:49 pm - 2:48 am
DEN
-
SCL
24h 59m
1 stop
Copa Airlines Logo
12:15 pm - 5:02 pm
SCL
-
DEN
32h 47m
1 stop
$581Copa Airlines
Fri, Nov 6 - Tue, Nov 10
LATAM Airlines Logo
12:59 am - 2:48 pm
DEN
-
SCL
33h 49m
2 stops
LATAM Airlines Logo
7:30 pm - 6:04 pm
SCL
-
DEN
26h 34m
2 stops
$593LATAM Airlines
Wed, Oct 28 - Sun, Nov 1
LATAM Airlines Logo
10:45 am - 6:55 am
DEN
-
SCL
17h 10m
2 stops
LATAM Airlines Logo
11:05 pm - 12:23 am
SCL
-
DEN
29h 18m
2 stops
$598LATAM Airlines
Sat, Nov 7 - Tue, Nov 10
United Airlines Logo
7:31 pm - 8:50 am
DEN
-
SCL
33h 19m
1 stop
United Airlines Logo
10:45 pm - 2:15 pm
SCL
-
DEN
19h 30m
1 stop
$601United Airlines
Mon, Oct 19 - Sat, Oct 24
LATAM Airlines Logo
4:40 pm - 5:35 am
DEN
-
SCL
33h 55m
2 stops
LATAM Airlines Logo
4:30 pm - 6:04 pm
SCL
-
DEN
28h 34m
2 stops
$614LATAM Airlines
Sun, Oct 11 - Mon, Oct 19
Delta Logo
6:25 pm - 5:35 am
DEN
-
SCL
32h 10m
2 stops
Delta Logo
8:40 pm - 11:54 am
SCL
-
DEN
18h 14m
1 stop
$615Delta
Mon, Oct 19 - Sun, Oct 25
Copa Airlines Logo
10:43 pm - 8:32 pm
DEN
-
SCL
18h 49m
1 stop
Copa Airlines Logo
12:23 pm - 6:11 pm
SCL
-
DEN
32h 48m
1 stop
$623Copa Airlines
Thu, Oct 1 - Sun, Oct 11
LATAM Airlines Logo
7:15 am - 1:25 pm
DEN
-
SCL
27h 10m
3 stops
LATAM Airlines Logo
9:40 pm - 9:35 am
SCL
-
DEN
14h 55m
1 stop
$624LATAM Airlines
Sun, Nov 8 - Wed, Nov 18
LATAM Airlines Logo
4:40 pm - 5:40 am
DEN
-
SCL
33h 00m
2 stops
LATAM Airlines Logo
11:05 pm - 6:04 pm
SCL
-
DEN
22h 59m
2 stops
$625LATAM Airlines
Sat, Sep 26 - Sat, Oct 3
Copa Airlines Logo
10:43 pm - 3:56 am
DEN
-
SCL
26h 13m
1 stop
Copa Airlines Logo
5:15 am - 6:11 pm
SCL
-
DEN
15h 56m
1 stop
$627Copa Airlines
Booking Insights

KAYAK's insights & trends for Denver to Santiago flights

Get data-powered insights and trends into flights from Denver to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Denver to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Denver to Santiago departing in November.

What is the cheapest month to fly from Denver to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Santiago is January, where tickets cost $679 (return) on average. On the other hand, the most expensive months are July and December, where the average cost of round-trip tickets is $1,020 and $919 respectively.

How far in advance should I book a flight from Denver to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Santiago, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$355
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Denver to Santiago

When to book flights from Denver to Santiago

Are your dates flexible? Find out the best times to travel from Denver to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Denver to Santiago

  • What is the cheapest flight from Denver to Santiago?

    In the last 5 days, the lowest price for a flight from Denver to Santiago was $355 for a one-way ticket and $581 for a round-trip.

  • Do I need a passport to fly between Denver and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Denver and on arrival in Santiago.

  • Which airports will I be using when flying from Denver to Santiago?

    Denver and Santiago are both served by 1 main airport. You will leave Denver from Denver Intl and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Denver to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Denver to Santiago?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Denver and Santiago, with SkyTeam being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from Denver?

    Atlanta is the most popular layover city among KAYAK users traveling from Denver to Santiago.

  • Which is the best airline for flights from Denver to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Denver to Santiago are Delta and Copa Airlines. With an average price for the route of $759 and an overall rating of 7.8, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $751 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from Denver to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Denver is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Denver with another airline. Booking your flights between Denver and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Denver up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Denver to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8454 reviews
7.8Entertainment
8.1Boarding
8.5Crew
7.8Comfort
7.2Food
Airline reviews

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

4.0 OkayMarilyn, Jun 2026
DEN - ATL
Read more Delta reviews

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

worst flight ever from Delta, it got delayed and kept on delaying..

Terrible. Four hour delay because Delta could not find crew to man the aircraft. Terrible communication. Terrible insight into the delays. One of the worst flight experiences I’ve had.

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Boarding was organised and relaxed. Crew were fantastic! Seats were lacking padding causing butt pain and stiffness.

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

First, the flight was schedule to leave at 12:08. Delayed to 12:38. It is 12:58 and I am sitting at the gate. The staff are not communicating with us (just tell me it’s gonna be five hours if that’s the case, quit hufflepuffing around like you’re trying to board us when the plane isn’t even here and you don’t know where your crew are. I’m still waiting for any communication about the further delay. This is a rebooked flight from a cancelled flight yesterday, when the airline failed to fulfill its fiduciary responsibility to hotel and cover transport for overnight cancelations. Asking about the food on the flight? What food?!? Delta doesn’t serve meals unless you pay for them and you really want me to give delta a high rating for passing out processed snacks (fun size!)? Can we be for real. Delta is cementing itself in history as one of the cheap, stingy, outdated, glory days are over airlines, and it shows. I took this flight knowing delta was going to provide below level service but this is beyond burgers!! I can’t believe a multi billion or dollar company looked straight in my eyes yesterday and I told me this wasn’t their fault and there for the extra cost in hotel and hundreds of dollars in Ubers are MY RESPONSIBILITY. The only thing I am at fault for is believing delta is reputable company worthy of my dollars. I’m not even sure I want to be compensated unless it is cash because I would rather die never traveling again than to put money in their pockets.

Boarding was great. The flight landed early. It took the crew over an hour and a half to bring out drinks. I paid to upgrade my seat to Comfort+ only to be near a crying/screaming baby who was seldom quiet. Noise-cancelling earbuds didn’t even help. Waste of money to upgrade.

This flight was supposed to land at 10:55 pm on January 14th. Instead, it landed at 3:20 am on Monday, January 15th, resulting in a completely lost day due to not going to bed until 5:00 am.

We finally got on a flight about 10:45 that was to leave at 7:30. Bah humbug!

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was good, plane is a bit older so seats are somewhat flat

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

I needed internet for critical matters and it never worked.

Very easy ! Use the kiosk and bag drop and right to security within 10 min

The entertainment they offer could use some games, and maybe they could add some cookies to the snack menu. And the automated messages are a bit repetitive. But it was comfortable temperature wise and the seats were comfortable. The crew is very polite and helpful

This planes staff was top tier. Everything went great and had a great flight home.

Destroyed my suitcase. Tired of talking about it. Cancelling my unite mileage plus account.

New plane was lovely. Crew customer service is always lax but expected. Kraft on time and arrived safely.

It was a short flight so I was expecting too much

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

The flight attendants were extremely sourly and borderline rude. I did not feel appreciated as an AA customer once.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

Don’t know they cancelled the flight day before I was to leave. They sent a email at 9:00 pm at night saying they cancelled. That is the smooth way to say we don’t want your business! I think they didn’t have enough people booking so they cancelled the flight! It’s all about the money anymore there is no honesty in business.

Mechanical delay and no compensation. Missed connection as a result of their delay. Mediocre performance and service. Horrible airline currently with horrible culture.

Any sort of gluten free snack option would be nice

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Timely boarding process, made up for lost time even after a lengthy wait for de-icing

It would have been better if I could have had my flight on time. It was delayed for 5 hours. Caused me to not be able to fulfill my promise to my granddaughters. Other than that it was a good trip.

11h50m total delay. Had to switch to another flight that was still a 7h30m delay.

Everything you need to know for your flight from Denver to Santiago

Information on your arrival and departure airports