DEN - SCL

$440 Find Cheap Flights from Denver to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Santiago departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$685
Typical prices: $885-$694
American Airlines
Fri 10/30Sat 11/14
DEN - SCL • 1 stop
Cheapest one-way
$440
Multiple Airlines
Wed 7/22
DEN - SCL • 2 stops
Top airlines
Cheapest • from $685 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Denver and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $977 (round-trip)
Shortest trip • 14h 41m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 9% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 12% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Denver to Santiago (DEN-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Santiago

Fri, Oct 30 - Sat, Nov 14
American Airlines Logo
2:46 pm - 9:00 am
DEN
-
SCL
15h 14m
1 stop
American Airlines Logo
10:15 pm - 12:01 pm
SCL
-
DEN
17h 46m
1 stop
$685American Airlines
Fri, Oct 30 - Sat, Nov 14
American Airlines Logo
2:46 pm - 9:00 am
DEN
-
SCL
15h 14m
1 stop
American Airlines Logo
10:15 pm - 5:49 pm
SCL
-
DEN
23h 34m
2 stops
$690American Airlines
Sat, Aug 22 - Sat, Aug 29
GOL Logo
5:08 am - 6:50 am
DEN
-
SCL
23h 42m
2 stops
GOL Logo
8:30 pm - 9:40 pm
SCL
-
DEN
27h 10m
2 stops
$692GOL
Sat, Aug 22 - Sat, Aug 29
American Airlines Logo
11:55 pm - 6:50 am
DEN
-
SCL
28h 55m
1 stop
American Airlines Logo
8:30 pm - 11:01 pm
SCL
-
DEN
28h 31m
1 stop
$708American Airlines
Fri, Oct 30 - Sat, Nov 14
American Airlines Logo
10:43 am - 9:00 am
DEN
-
SCL
19h 17m
2 stops
American Airlines Logo
10:15 pm - 5:49 pm
SCL
-
DEN
23h 34m
2 stops
$745American Airlines
Tue, Jul 7 - Mon, Aug 10
GOL Logo
11:59 pm - 7:00 am
DEN
-
SCL
29h 01m
2 stops
GOL Logo
8:30 pm - 12:30 pm
SCL
-
DEN
18h 00m
2 stops
$747GOL
Mon, Oct 19 - Sat, Oct 24
LATAM Airlines Logo
12:00 pm - 8:15 am
DEN
-
SCL
17h 15m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
21h 45m
1 stop
$752LATAM Airlines
Mon, Oct 19 - Sat, Oct 24
LATAM Airlines Logo
12:00 pm - 8:15 am
DEN
-
SCL
17h 15m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
21h 45m
1 stop
$768LATAM Airlines
Thu, Oct 15 - Sat, Nov 7
LATAM Airlines Logo
12:00 pm - 6:55 am
DEN
-
SCL
15h 55m
2 stops
LATAM Airlines Logo
11:05 pm - 6:04 pm
SCL
-
DEN
22h 59m
2 stops
$770LATAM Airlines
Mon, Oct 19 - Fri, Oct 23
Copa Airlines Logo
10:43 pm - 11:39 pm
DEN
-
SCL
21h 56m
1 stop
Copa Airlines Logo
3:28 am - 6:11 pm
SCL
-
DEN
17h 43m
1 stop
$773Copa Airlines
Booking Insights

KAYAK's insights & trends for Denver to Santiago flights

Get data-powered insights and trends into flights from Denver to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Denver to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Denver to Santiago departing in October.

What is the cheapest month to fly from Denver to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Santiago is September, where tickets cost $681 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $919 and $881 respectively.

How far in advance should I book a flight from Denver to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Santiago, you should book around 3 weeks before departure, which saves you about 9% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$440
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from Denver to Santiago

When to book flights from Denver to Santiago

Are your dates flexible? Find out the best times to travel from Denver to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Denver to Santiago

  • What is the cheapest flight from Denver to Santiago?

    In the last 3 days, the lowest price for a flight from Denver to Santiago was $440 for a one-way ticket and $685 for a round-trip.

  • Do I need a passport to fly between Denver and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Denver and on arrival in Santiago.

  • Which airports will I be using when flying from Denver to Santiago?

    Denver and Santiago are both served by 1 main airport. You will leave Denver from Denver Intl and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Denver to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Denver to Santiago?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Denver and Santiago, with oneworld being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from Denver?

    Atlanta is the most popular layover city among KAYAK users traveling from Denver to Santiago.

  • Which is the best airline for flights from Denver to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Denver to Santiago are Delta and Copa Airlines. With an average price for the route of $755 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $713 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Denver to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Denver is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Denver with another airline. Booking your flights between Denver and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Denver up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Denver to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8452 reviews
7.2Food
7.8Comfort
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

6.0 GoodAnonymous, May 2026
PDX - MSP
Read more Delta reviews

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Do not book it’s a scam! They stole $1200 from me

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

Putting people that close to the bathroom, where you have to look into the bathroom as people are exiting and entering was not great and the smell was also not great. I know the airlines are desperate for more chairs, but that seat is a crime.

Every staff member was professional, friendly and courteous. The pizza twist was ok. It was warm but too much dough.

one staffer was frustrated (it happen); the flight was late and the pilot mentioned they'll make amend but the snacks were the same, other than that the aircraft was clean and everything went smooth, no complaints

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

No seat back entertainment. And app had a hard time getting entertainment loaded.

ticket agent lady wás very helpful , she arranged wheel chair for my elderly mother

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Flight was delayed an no one cares, or try to help passengers to get the conexión.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

The small flights with Valet Luggage has a poor service

Terrible, horrible, disappointing- without telling us they changed planes and moved and separated our seats to opposite sides - said they changed seats putting us together - got to airport to find no, they did not - we sat opposing sides of plane - food overly salty to inedible, never saw stewardess but once - it was terrible

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

The crew was very attentive through out the flight. Seats were comfortable, nice flight bag with pillow and blanket. Food was okay, since it was a overnight flight seemed to go by fast.

Everything you need to know for your flight from Denver to Santiago

Information on your arrival and departure airports