DEN - SCL

$281 Find Cheap Flights from Denver to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Santiago departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago.
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Everything you should know

Cheapest round-trip
$665
Overall average: $753
Multiple Airlines
Tue 4/21Tue 4/28
DEN - SCL • 2 stops
Cheapest one-way
$281
Typical prices: $560-$576
Multiple Airlines
Thu 5/7
DEN - SCL • 3 stops
Top airlines
Cheapest • from $673 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Denver and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $959 (round-trip)
Shortest trip • 14h 39m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 14% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 17% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Denver to Santiago (DEN-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Santiago

Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
11:05 pm - 5:30 am
DEN
-
SCL
28h 25m
2 stops
Multiple Airlines Logo
8:20 pm - 12:14 pm
SCL
-
DEN
41h 54m
3 stops
$665Multiple Airlines
Tue, Apr 21 - Tue, Apr 28
Multiple Airlines Logo
7:05 pm - 5:30 am
DEN
-
SCL
32h 25m
3 stops
Multiple Airlines Logo
8:20 pm - 12:14 pm
SCL
-
DEN
41h 54m
3 stops
$666Multiple Airlines
Tue, Apr 21 - Mon, Apr 27
Multiple Airlines Logo
11:05 pm - 5:30 am
DEN
-
SCL
28h 25m
2 stops
Multiple Airlines Logo
12:55 am - 9:40 am
SCL
-
DEN
34h 45m
2 stops
$671Multiple Airlines
Wed, Jun 24 - Wed, Jul 8
LATAM Airlines Logo
12:29 pm - 5:35 am
DEN
-
SCL
15h 06m
1 stop
LATAM Airlines Logo
11:25 pm - 6:18 pm
SCL
-
DEN
20h 53m
1 stop
$673LATAM Airlines
Tue, Sep 1 - Wed, Sep 30
LATAM Airlines Logo
6:30 am - 5:35 am
DEN
-
SCL
21h 05m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
21h 45m
1 stop
$689LATAM Airlines
Wed, Jun 24 - Tue, Jul 7
LATAM Airlines Logo
12:29 pm - 5:35 am
DEN
-
SCL
15h 06m
1 stop
LATAM Airlines Logo
12:40 am - 5:56 pm
SCL
-
DEN
19h 16m
2 stops
$694LATAM Airlines
Mon, Jul 13 - Sun, Jul 26
LATAM Airlines Logo
12:29 pm - 5:35 am
DEN
-
SCL
15h 06m
1 stop
LATAM Airlines Logo
11:00 pm - 5:56 pm
SCL
-
DEN
20h 56m
2 stops
$700LATAM Airlines
Sun, Aug 9 - Thu, Aug 20
LATAM Airlines Logo
12:29 pm - 5:35 am
DEN
-
SCL
15h 06m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
20h 45m
1 stop
$704LATAM Airlines
Wed, May 6 - Thu, May 14
Multiple Airlines Logo
9:06 pm - 5:30 am
DEN
-
SCL
54h 24m
3 stops
Multiple Airlines Logo
8:20 pm - 12:09 am
SCL
-
DEN
53h 49m
3 stops
$705Multiple Airlines
Tue, Sep 1 - Wed, Sep 30
LATAM Airlines Logo
7:05 am - 5:35 am
DEN
-
SCL
20h 30m
2 stops
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
21h 45m
1 stop
$709LATAM Airlines
Booking Insights

KAYAK's insights & trends for Denver to Santiago flights

Get data-powered insights and trends into flights from Denver to Santiago to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Denver to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Santiago is September, where tickets cost $663 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $1,152 and $953 respectively.

How far in advance should I book a flight from Denver to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Santiago, you should book around 3 weeks before departure, which saves you about 14% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$281
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly with an average 44% increase in price.
Flight from Denver to Santiago

When to book flights from Denver to Santiago

Are your dates flexible? Find out the best times to travel from Denver to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Denver to Santiago

  • What is the cheapest flight from Denver to Santiago?

    In the last 3 days, the lowest price for a flight from Denver to Santiago was $281 for a one-way ticket and $665 for a round-trip.

  • Do I need a passport to fly between Denver and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Denver and on arrival in Santiago.

  • Which airports will I be using when flying from Denver to Santiago?

    Denver and Santiago are both served by 1 main airport. You will leave Denver from Denver Intl and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Denver to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Denver to Santiago?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Denver and Santiago, with oneworld being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from Denver?

    Atlanta is the most popular layover city among KAYAK users traveling from Denver to Santiago.

  • Which is the best airline for flights from Denver to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Denver to Santiago are Delta and Copa Airlines. With an average price for the route of $765 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $696 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Denver to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Denver is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Denver with another airline. Booking your flights between Denver and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Denver up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Denver to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8321 reviews
8.5Crew
7.9Comfort
7.2Food
8.1Boarding
7.8Entertainment
Airline reviews

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

2.0 MediocreSreekumar, Mar 2026
FLL - DTW
Read more Delta reviews

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Entertainment is ok! Boarding and seat with zone is terrible. I paid for the seats but you didn’t give me what I paid for which is exit isles.

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

Do not book it’s a scam! They stole $1200 from me

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

No seat back entertainment. And app had a hard time getting entertainment loaded.

ticket agent lady wás very helpful , she arranged wheel chair for my elderly mother

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Sitting on the runway after we land for almost two hours! Not sure if we should blame United or Just Dumpy Vance.

Flight was late - I was downgraded from first class to coach

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

Flight was good but there are way to many announcements for credit cards etc.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

See previous note about the passenger in Denver who threw my husband's bag out of the overhead bin in order to maker room for his own. And the flight attendant back up the new passenger.

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Half of the TSA checkpoints at PHL are closed. Also, there is no standby for first class passengers. You can only standby for coach. Very dated policy and inconsistent with peers.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Great experience. Good dinner and service. FA's were very nice and attentive.

It was great. Smooth flight, comfortable, left on time and landed on time.

Perhaps this is an airport issue, but being in a takeoff queue for over an hour in the taxiing lane is unacceptable. We will definitely be seeking alternative avenues for air travel in the future.

We hoarded. Then we deplaned. Then we waited for 10 hours in the MSP airport due to a wheel misfunction. We understand safety but communication between crew and airport staff was horrible. When we did finally board, we were rushed on and because we were waiting for a “fresh” pilot and crew, we sat in a roasting plane with no A/C for an hour. My question is why was this flight not cancelled right away when they knew this would be a huge issue OR, why did AA not get a substitute plane, considering this was already a full flight? To me, this appears to be a complete breakdown in leadership and utter systems failure. The compensation for completely disrupting travel plans for hundreds, which we paid dearly for, was measly. While we appreciated the lodging for the night, $12 in meal vouchers isn’t going to sustain anyone for over 12 hours. “We apologize; our hands are tied” is no longer an acceptable explanation. We are so completely turned off by this experience and will definitely seek alternative avenues when we need to fly.

Mostly good. The WiFi wasn’t working so that was not great.

Everything you need to know for your flight from Denver to Santiago

Information on your arrival and departure airports