DEN - SCL

$259 Find Cheap Flights from Denver to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Santiago departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago.
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Cheap Flights from Denver to Santiago (DEN-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Santiago

Tue, Nov 4 - Thu, Nov 20
LATAM Airlines Logo
6:15 am - 6:00 amDEN-SCL
19h 45m1 stop
LATAM Airlines Logo
11:55 pm - 11:30 amSCL-DEN
15h 35m1 stop
$544LATAM Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 14
LATAM Airlines Logo
7:05 am - 5:35 amDEN-SCL
18h 30m2 stops
LATAM Airlines Logo
10:35 am - 11:47 pmSCL-DEN
17h 12m2 stops
$548LATAM Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 14
American Airlines Logo
2:51 pm - 7:50 amDEN-SCL
12h 59m1 stop
American Airlines Logo
11:15 pm - 11:17 amSCL-DEN
16h 02m1 stop
$554American Airlines
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Thu, Dec 4 - Sun, Dec 14
American Airlines Logo
2:51 pm - 7:50 amDEN-SCL
12h 59m1 stop
American Airlines Logo
11:15 pm - 1:28 pmSCL-DEN
18h 13m2 stops
$558American Airlines
Find Deal
Wed, Oct 29 - Thu, Nov 20
United Airlines Logo
3:41 pm - 7:50 amDEN-SCL
13h 09m1 stop
United Airlines Logo
10:45 pm - 4:09 pmSCL-DEN
21h 24m1 stop
$564United Airlines
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Sun, Nov 2 - Fri, Nov 7
Copa Airlines Logo
9:36 pm - 11:41 pmDEN-SCL
22h 05m1 stop
Copa Airlines Logo
3:23 am - 5:17 pmSCL-DEN
17h 54m1 stop
$572Copa Airlines
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Sun, Nov 2 - Mon, Nov 17
Delta Logo
4:47 pm - 7:00 amDEN-SCL
34h 13m1 stop
Delta Logo
10:50 am - 11:47 pmSCL-DEN
16h 57m2 stops
$587Delta
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Fri, Oct 31 - Mon, Nov 17
United Airlines Logo
3:41 pm - 7:50 amDEN-SCL
13h 09m1 stop
United Airlines Logo
10:45 pm - 10:05 amSCL-DEN
15h 20m1 stop
$604United Airlines
Find Deal
Sun, Nov 2 - Fri, Nov 21
Delta Logo
4:47 pm - 7:00 amDEN-SCL
34h 13m1 stop
Delta Logo
11:15 pm - 2:58 pmSCL-DEN
19h 43m1 stop
$618Delta
Find Deal
Thu, Nov 6 - Sun, Nov 9
Copa Airlines Logo
9:36 pm - 3:24 amDEN-SCL
25h 48m1 stop
Copa Airlines Logo
3:23 am - 5:17 pmSCL-DEN
17h 54m1 stop
$634Copa Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Denver to Santiago flights

Get data-powered insights and trends into flights from Denver to Santiago to help you find the cheapest flights, the best time to fly and much more.

What is the most popular layover airport when flying from Denver to Santiago?

Percentage of 1-stop round-trip flights from Denver to Santiago chosen by KAYAK users via each layover airport in the last 12 months (only includes trips with the same layover airport on both legs).

Atlanta (ATL) is the top choice – 26% of KAYAK users who clicked on 1-stop flights from Denver to Santiago picked an itinerary connecting there.

What is the cheapest layover airport when flying from Denver to Santiago?

Average round-trip price for 1-stop flights from Denver to Santiago clicked by KAYAK users in the last 12 months (only includes trips with the same layover airport on both legs).

Flights via Miami (MIA) offer the most affordable fares, with an average round-trip price of $947.

Which layover airport offers the shortest total travel time from Denver to Santiago?

Shortest average total travel time for 1-stop one-way flights from Denver to Santiago via different layover airports, based on KAYAK user data from the last 12 months.

Consider flying via Dallas (DFW) for the shortest journey. The average one-way travel time for flights connecting there is 13h 54m.

Which layover airport has the quickest connection when flying from Denver to Santiago?

Average layover duration at different layover airports for 1-stop one-way flights from Denver to Santiago, based on KAYAK user data from the last 12 months.

If you prefer a quick connection, Dallas (DFW) often has the shortest layovers from Denver to Santiago, with an average of 2h 24m.

Good to know

Low seasonJune
Cheapest flight$259
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly with an average 47% increase in price.
Flight from Denver to Santiago

When to book flights from Denver to Santiago

Are your dates flexible? Find out the best times to travel from Denver to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Reviews of the top 5 airlines serving from Denver to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Denver to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
8.2Boarding
7.9Comfort
7.9Entertainment
7.3Food
8.5Crew
Airline reviews

Delayed and took off even later than the scheduled delay time

8.0 ExcellentAnonymous, Jul 2025DTW - SEA
Read more Delta reviews

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Only issue was with seating. The economy fare we purchased did say there was no guarantee the three people in our party would be seated together, and we were not. At the gate, the agent told us more specifically, the fare we purchased meant we would be seated in middle seats only. This should just be made more obvious.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Everything was good until we were boarding our connection flight in Atlanta, we were told to gate check our carry-on, but when we got inside the plane, there was plenty of room in the overhead.

Did not know my son and I had different seating arrangements. He was fine, but it was disappointing.

Flight was canceled, and no effort was made to help with rebooking, no hotel vouchers, no car transportation and minimal food voucher and most places for food were closed by the time the voucher was given. Waited for 3 hours for bags. Simply the worst travel experience I have ever had

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Seats not reclining, no vegetarian food option, no snacks. 7.5 hr flight should have been more comfortable. Luggage limits are unusually small. Will never fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

It was ok. However, the food was quite poor since I don't eat pasta.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

The seat and leg room was not good. The food and beverage service was good.

For economy, it was very good. Staff was great, they even let some of us change seats for more leg room... Put an empty seat between us which was fantastic for a 12hr flight. Onboard entertainment was excellent, I think over 200 choices of movies/tv/etc The bad was the barely/nonfunctional wifi that cost either $16.99 or 1700 miles (full flight). It was atrocious... Definitely the worst of the last 3 long haul major airlines I was on the last few months.

Electric plugs didn't work. Entertainment system wasn't working

The design of the light switch on the arm rest is ridiculous.

The gate attendant let me walk right by her with a bag too big for the overhead compartment

Overall, it was a good experience. Boarding was good and there was plenty of overhead bin space for everyone’s carryons (even when we boarded toward the end). Only improvement would be to offer trash service more regularly.

David went above and beyond to make our flight the best that it could be

No food service almost missed because of first flight delays

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

The plane was broken so we had to change planes.

The flight got delayed 2.5 hrs due to a maintenance issue that cause a domino effect. American should have spare planes for when something like this happens.

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