DEN - SCL

$257 Find Cheap Flights from Denver to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Denver to Santiago departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Denver to Santiago.
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Flight Deals

Cheap Flights from Denver to Santiago (DEN-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Denver to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Denver to Santiago

Fri, Feb 13 - Thu, Feb 26
LATAM Airlines Logo
2:59 pm - 3:30 pmDEN-SCL
20h 31m2 stops
LATAM Airlines Logo
10:15 pm - 10:49 pmSCL-DEN
28h 34m2 stops
$544LATAM Airlines
Find Deal
Sun, Mar 1 - Thu, Mar 12
Delta Logo
6:05 am - 7:00 amDEN-SCL
20h 55m2 stops
Delta Logo
12:25 am - 11:54 pmSCL-DEN
26h 29m2 stops
$548Delta
Find Deal
Tue, Feb 10 - Thu, Feb 26
LATAM Airlines Logo
7:05 am - 7:00 amDEN-SCL
19h 55m1 stop
LATAM Airlines Logo
10:15 pm - 10:49 pmSCL-DEN
28h 34m2 stops
$554LATAM Airlines
Find Deal
Sun, Mar 1 - Tue, Mar 10
Delta Logo
7:05 am - 7:00 amDEN-SCL
19h 55m2 stops
Delta Logo
11:15 pm - 6:10 pmSCL-DEN
21h 55m1 stop
$558Delta
Find Deal
Thu, Jan 29 - Tue, Feb 17
United Airlines Logo
5:25 pm - 8:50 amDEN-SCL
35h 25m1 stop
United Airlines Logo
10:45 pm - 2:32 pmSCL-DEN
19h 47m1 stop
$562United Airlines
Find Deal
Mon, Feb 9 - Fri, Feb 27
Delta Logo
4:40 pm - 7:00 amDEN-SCL
34h 20m1 stop
Delta Logo
5:15 am - 10:49 pmSCL-DEN
21h 34m2 stops
$563Delta
Find Deal
Tue, Feb 10 - Tue, Feb 24
Delta Logo
1:30 pm - 7:00 amDEN-SCL
13h 30m1 stop
Delta Logo
8:20 am - 10:49 pmSCL-DEN
18h 29m2 stops
$564Delta
Find Deal
Wed, Feb 4 - Tue, Feb 24
American Airlines Logo
6:52 am - 9:05 amDEN-SCL
22h 13m1 stop
American Airlines Logo
10:15 pm - 1:02 pmSCL-DEN
18h 47m2 stops
$568American Airlines
Find Deal
Tue, Feb 10 - Tue, Feb 24
United Airlines Logo
8:32 pm - 8:50 amDEN-SCL
32h 18m1 stop
United Airlines Logo
10:45 pm - 2:32 pmSCL-DEN
19h 47m1 stop
$572United Airlines
Find Deal
Wed, Feb 4 - Tue, Feb 24
American Airlines Logo
11:37 am - 9:05 amDEN-SCL
17h 28m2 stops
American Airlines Logo
10:15 pm - 6:09 pmSCL-DEN
23h 54m1 stop
$579American Airlines
Find Deal

Everything you should know

Top airlines
LATAM Airlines
Cheapest • from $544 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 19% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 12% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$544
Typical prices: $683-932
LATAM Airlines
Fri 2/13Thu 2/26
DEN - SCL • 2 stops
Cheapest one-way
$257
Typical prices: $479-600
Multiple Airlines
Mon 11/10
DEN - SCL • 2 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Booking Insights

KAYAK's insights & trends for Denver to Santiago flights

Get data-powered insights and trends into flights from Denver to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Denver to Santiago?

What’s the cheapest day of the week to fly from Denver to Santiago?

The average price of all round-trip flights from Denver to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Denver to Santiago, you should consider leaving on a Tuesday and avoid Saturdays if you are looking for the best rates. For your return to Denver, you’ll find the best rates on Tuesdays and the most expensive ones on Saturdays.

What is the cheapest month to fly from Denver to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Denver to Santiago is April, where tickets cost $752 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $1,355 and $926 respectively.

How far in advance should I book a flight from Denver to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Denver to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Denver to Santiago, you should book around 5 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonJune
Cheapest flight$257
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 58% increase in price.
Flight from Denver to Santiago

When to book flights from Denver to Santiago

Are your dates flexible? Find out the best times to travel from Denver to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Denver to Santiago

  • What is the cheapest flight from Denver to Santiago?

    In the last 3 days, the lowest price for a flight from Denver to Santiago was $257 for a one-way ticket and $544 for a round-trip.

  • Do I need a passport to fly between Denver and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Denver and on arrival in Santiago.

  • Which airports will I be using when flying from Denver to Santiago?

    Denver and Santiago are both served by 1 main airport. You will leave Denver from Denver Intl and will be arriving at Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Denver to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Denver to Santiago?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Denver and Santiago, with Star Alliance being the most commonly used for this route.

  • What is the most popular layover when flying to Santiago from Denver?

    Atlanta is the most popular layover city among KAYAK users traveling from Denver to Santiago.

  • Which is the best airline for flights from Denver to Santiago, Delta or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Denver to Santiago are Delta and Copa Airlines. With an average price for the route of $856 and an overall rating of 7.9, Delta is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $690 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from Denver to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Denver to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Denver to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Denver is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Denver to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Denver with another airline. Booking your flights between Denver and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Denver to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Denver up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Denver to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Denver to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Denver to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7954 reviews
7.9Comfort
7.3Food
7.9Entertainment
8.2Boarding
8.5Crew
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

The food was terrible especially for a 15 hour international flight. The crew was unpleasant as well.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

It was ok. However, the food was quite poor since I don't eat pasta.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

The seat and leg room was not good. The food and beverage service was good.

For economy, it was very good. Staff was great, they even let some of us change seats for more leg room... Put an empty seat between us which was fantastic for a 12hr flight. Onboard entertainment was excellent, I think over 200 choices of movies/tv/etc The bad was the barely/nonfunctional wifi that cost either $16.99 or 1700 miles (full flight). It was atrocious... Definitely the worst of the last 3 long haul major airlines I was on the last few months.

Electric plugs didn't work. Entertainment system wasn't working

The design of the light switch on the arm rest is ridiculous.

The gate attendant let me walk right by her with a bag too big for the overhead compartment

Overall, it was a good experience. Boarding was good and there was plenty of overhead bin space for everyone’s carryons (even when we boarded toward the end). Only improvement would be to offer trash service more regularly.

David went above and beyond to make our flight the best that it could be

No food service almost missed because of first flight delays

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

American airlines suck they delay the flights all the time made me sleep in an airport because my flight was delayed and I miss my connecting flight

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Don’t know they cancelled the flight day before I was to leave. They sent a email at 9:00 pm at night saying they cancelled. That is the smooth way to say we don’t want your business! I think they didn’t have enough people booking so they cancelled the flight! It’s all about the money anymore there is no honesty in business.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

It took way too long to diagnose and solve the problem of a broken crew member cabin seat. Though compensation for the volunteer who left the flight was very kind.

The entertainment package was vast and the selections were very current. Keep updating it was great.

Everything you need to know for your flight from Denver to Santiago

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