DSM - GUA

$280 Find Cheap Flights from Des Moines to Guatemala City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Guatemala City departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$601
Multiple Airlines
Sat 8/29Sat 9/5
DSM - GUA • 2 stops
Cheapest one-way
$280
Multiple Airlines
Sun 9/13
DSM - GUA • 3 stops
Top airlines
Cheapest • from $710 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Guatemala City. You'll need at least 1 connection.
Insights
Insights
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Insights
Top layover airports
Cheapest • Avg $660 (round-trip)
Shortest trip • 6h 56m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Guatemala City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Guatemala City (DSM-GUA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Guatemala City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Guatemala City

Sat, Aug 29 - Sat, Sep 5
Multiple Airlines Logo
1:21 pm - 11:10 pm
DSM
-
GUA
10h 49m
2 stops
Multiple Airlines Logo
5:25 am - 10:30 pm
GUA
-
DSM
16h 05m
2 stops
$601Multiple Airlines
Sat, Aug 29 - Sat, Sep 5
Multiple Airlines Logo
1:21 pm - 11:10 pm
DSM
-
GUA
10h 49m
2 stops
Multiple Airlines Logo
5:25 am - 10:30 pm
GUA
-
DSM
16h 05m
2 stops
$602Multiple Airlines
Tue, Nov 10 - Tue, Nov 24
American Airlines Logo
5:00 am - 8:14 pm
DSM
-
GUA
15h 14m
2 stops
American Airlines Logo
6:36 am - 2:59 pm
GUA
-
DSM
8h 23m
1 stop
$710American Airlines
Wed, Nov 18 - Tue, Dec 1
American Airlines Logo
7:04 am - 8:14 pm
DSM
-
GUA
13h 10m
2 stops
American Airlines Logo
6:36 am - 10:19 pm
GUA
-
DSM
15h 43m
2 stops
$715American Airlines
Wed, Nov 18 - Tue, Dec 1
American Airlines Logo
3:39 pm - 10:43 pm
DSM
-
GUA
7h 04m
1 stop
American Airlines Logo
6:36 am - 2:59 pm
GUA
-
DSM
8h 23m
1 stop
$725American Airlines
Tue, Jan 5 - Tue, Jan 19
American Airlines Logo
5:39 pm - 2:07 pm
DSM
-
GUA
20h 28m
1 stop
American Airlines Logo
6:32 am - 11:23 pm
GUA
-
DSM
16h 51m
1 stop
$732American Airlines
Sun, Aug 23 - Sun, Aug 30
Multiple Airlines Logo
6:00 am - 7:00 pm
DSM
-
GUA
14h 00m
1 stop
Multiple Airlines Logo
8:20 am - 5:28 pm
GUA
-
DSM
8h 08m
1 stop
$745Multiple Airlines
Mon, Oct 12 - Mon, Oct 19
American Airlines Logo
7:42 pm - 2:14 pm
DSM
-
GUA
19h 32m
2 stops
American Airlines Logo
2:05 pm - 9:15 am
GUA
-
DSM
18h 10m
2 stops
$749American Airlines
Sun, Nov 29 - Thu, Dec 10
American Airlines Logo
3:39 pm - 10:43 pm
DSM
-
GUA
7h 04m
1 stop
American Airlines Logo
6:31 am - 2:55 pm
GUA
-
DSM
8h 24m
1 stop
$750American Airlines
Sun, Nov 29 - Thu, Dec 10
American Airlines Logo
3:39 pm - 10:43 pm
DSM
-
GUA
7h 04m
1 stop
American Airlines Logo
11:33 am - 10:48 pm
GUA
-
DSM
11h 15m
2 stops
$754American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Guatemala City flights

Get data-powered insights and trends into flights from Des Moines to Guatemala City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Guatemala City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Guatemala City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Guatemala City is September, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and November, where the average cost of round-trip tickets is $895 and $862 respectively.

Good to know

Low season

February

Cheapest flight

$280
Best time to beat the crowds with an average 37% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Des Moines to Guatemala City

When to book flights from Des Moines to Guatemala City

Are your dates flexible? Find out the best times to travel from Des Moines to Guatemala City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Guatemala City

  • What is the cheapest flight from Des Moines to Guatemala City?

    In the last 5 days, the lowest price for a flight from Des Moines to Guatemala City was $280 for a one-way ticket and $601 for a round-trip.

  • Do I need a passport to fly between Des Moines and Guatemala City?

    Yes, you’ll need a passport to travel to Guatemala City from Des Moines.

  • Which aircraft models fly most regularly from Des Moines to Guatemala City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Guatemala City?

    oneworld, and Star Alliance are the airline alliances operating flights between Des Moines and Guatemala City, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Guatemala City, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Guatemala City are United Airlines and American Airlines. With an average price for the route of $723 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $728 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Guatemala City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Guatemala City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Guatemala City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guatemala City from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Guatemala City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guatemala City with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and GUA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Guatemala City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guatemala City from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Guatemala City

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Guatemala City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Guatemala City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10006 reviews
7.1Entertainment
7.3Comfort
8.1Crew
7.7Boarding
6.6Food
Airline reviews

I almost missed my connection in Chicago due to having to wait on a gate to be open I am assuming. Having to run from E terminal to C terminal and I barely made it there before they closed the door. This may not be the actual airline's fault it's crazy how there is so little time between flight especially when they are placed so far apart in the airport.

8.0 ExcellentSherry, Jul 2026
COU - ORD
Read more United Airlines reviews

I almost missed my connection in Chicago due to having to wait on a gate to be open I am assuming. Having to run from E terminal to C terminal and I barely made it there before they closed the door. This may not be the actual airline's fault it's crazy how there is so little time between flight especially when they are placed so far apart in the airport.

Unbelievably smooth boarding at IAH and the flight attendants were top notch.

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

The Crew and the food was the worst I ever had in Business Class. First they told us there were no space for carry on. It was plenty of space over our 2 row seats, we had to ask to let us travel with it which was accepted. They were aware that we had to run for the connection due to the previous flight delay. Have us one hour waiting for more customers and not even offer a glass of water. Then started the service and they started to serve other passengers drinks in business and did not offer any drinks until they serve our pre ordered meal and I ask for something to drink. I had to wait until they finished to serve all passengers until Inget something. The crew was the worts I ever had for Business Class in my life.

Very rough getting into denver. my kid threw up it was so rough.

Flight delayed over 2 hours . I was flying bussiness never got food cause they ran out of what i wanted

Liked that we left on time for each flight. Snacks not the best, but we're okay.

I had requested wheelchair assistance prior to flight. The airport staff had no record of it. It was not provided at Cedar Rapids which was a small airport, so I managed on my own. At O'Hare airport the same thing happened. The staff told me they had no record of my request for a wheel chair. But they finally provided it after a delay when I insisted that I needed it.

Boarding and Delays The boarding process for my American Airlines flight from Copenhagen to Philadelphia was a bit tricky. We experienced a gate change that required a long walk to a new area of the airport. Additionally, boarding was not via a jet bridge; we had to take a shuttle bus to the plane and then carry our luggage up the stairs ourselves. Furthermore, the bag drop didn't open until about 12:20 PM, which was only three hours before our scheduled departure. This meant I couldn't drop my bag off early and had to wait outside of security in order to drop off my bag and use the kiosk. The bag drop self-service kiosks also didn't open until about 12:00 PM when an American Airlines employee unlocked them so that we could print out our boarding passes and bag tags, which further created a backlog. The flight was delayed by over an hour because we had to wait for one of the tires on the plane to be changed. Flight Attendant Professionalism On a positive note, the flight attendant was very professional when handling a passenger who was sitting in the wrong seat. Even though the passenger was persistent and reluctant to move, the flight attendant calmly ensured the assigned passenger could take their seat. Kudos to the flight attendant for keeping his calm and composure, not allowing the issue to escalate, and handling it well under pressure while a line of passengers waited in the aisle to board. In-Flight Service The in-flight service was also fast, prompt, and efficient, although service had to be suspended for the last two hours of the flight due to weather and turbulence, which was outside of the crew's control. Limited Flight Options Please note that American Airlines only operates one flight per day in and out of Copenhagen. This means there are limited options available if your flight is delayed or canceled, which is something to take into consideration when booking.

Not one thing to like. Three flights all with “mechanical” delays. Never got to where I was going and spent additional $500 for a hotel room. American Airlines is the worst in the industry!

the seat was not padded at all - uncomfortable after a 3 hour flight

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.

Everything you need to know for your flight from Des Moines to Guatemala City

Information on your arrival and departure airports