DSM - GUA

$680 Find Cheap Flights from Des Moines to Guatemala City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Guatemala City departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Guatemala City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Guatemala City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Guatemala City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$680
Typical prices: $686-$583
American Airlines
Wed 10/21Fri 10/30
DSM - GUA • 2 stops
Top airlines
Cheapest • from $680 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Guatemala City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $660 (round-trip)
Shortest trip • 6h 57m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 33% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guatemala City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Guatemala City (DSM-GUA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Guatemala City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Guatemala City

Wed, Oct 21 - Fri, Oct 30
American Airlines Logo
6:00 am - 6:15 pm
DSM
-
GUA
13h 15m
2 stops
American Airlines Logo
3:00 pm - 8:07 am
GUA
-
DSM
16h 07m
2 stops
$680American Airlines
Thu, Aug 13 - Fri, Aug 21
American Airlines Logo
7:49 pm - 1:22 pm
DSM
-
GUA
18h 33m
2 stops
American Airlines Logo
2:23 pm - 10:15 am
GUA
-
DSM
18h 52m
2 stops
$687American Airlines
Thu, Aug 13 - Fri, Aug 21
American Airlines Logo
7:35 pm - 1:22 pm
DSM
-
GUA
18h 47m
1 stop
American Airlines Logo
2:23 pm - 10:15 am
GUA
-
DSM
18h 52m
2 stops
$699American Airlines
Wed, Oct 21 - Fri, Oct 30
American Airlines Logo
6:30 am - 1:24 pm
DSM
-
GUA
7h 54m
1 stop
American Airlines Logo
12:04 pm - 11:07 pm
GUA
-
DSM
10h 03m
1 stop
$707American Airlines
Sat, Jul 11 - Tue, Jul 21
American Airlines Logo
4:48 pm - 11:32 pm
DSM
-
GUA
7h 44m
1 stop
American Airlines Logo
12:35 am - 8:18 pm
GUA
-
DSM
18h 43m
2 stops
$754American Airlines
Tue, Jul 14 - Mon, Jul 20
American Airlines Logo
5:00 am - 6:23 pm
DSM
-
GUA
14h 23m
2 stops
American Airlines Logo
12:35 am - 8:18 pm
GUA
-
DSM
18h 43m
2 stops
$759American Airlines
Thu, Aug 13 - Fri, Aug 21
American Airlines Logo
4:13 pm - 1:22 pm
DSM
-
GUA
22h 09m
1 stop
American Airlines Logo
12:07 pm - 9:01 am
GUA
-
DSM
19h 54m
1 stop
$781American Airlines
Wed, Aug 5 - Sun, Aug 16
American Airlines Logo
4:13 pm - 11:07 am
DSM
-
GUA
19h 54m
2 stops
American Airlines Logo
6:00 am - 12:20 am
GUA
-
DSM
17h 20m
2 stops
$784American Airlines
Wed, Aug 5 - Sun, Aug 16
Delta Logo
5:40 am - 11:29 am
DSM
-
GUA
6h 49m
1 stop
Delta Logo
12:59 pm - 10:37 pm
GUA
-
DSM
8h 38m
1 stop
$785Delta
Sat, Jul 11 - Tue, Jul 21
American Airlines Logo
1:34 pm - 11:32 pm
DSM
-
GUA
10h 58m
2 stops
American Airlines Logo
12:35 am - 8:18 pm
GUA
-
DSM
18h 43m
2 stops
$789American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Guatemala City flights

Get data-powered insights and trends into flights from Des Moines to Guatemala City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Guatemala City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Guatemala City departing in October.

What is the cheapest month to fly from Des Moines to Guatemala City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Guatemala City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Guatemala City is February, where tickets cost $468 (return) on average. On the other hand, the most expensive months are May and December, where the average cost of round-trip tickets is $802 and $773 respectively.

How far in advance should I book a flight from Des Moines to Guatemala City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Guatemala City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Guatemala City, you should book around 6 weeks before departure, which saves you about 17% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$680
Best time to beat the crowds with an average 30% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Des Moines to Guatemala City

When to book flights from Des Moines to Guatemala City

Are your dates flexible? Find out the best times to travel from Des Moines to Guatemala City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Guatemala City

  • What is the cheapest flight from Des Moines to Guatemala City?

    In the last 3 days, the lowest price for a flight from Des Moines to Guatemala City was $680 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Guatemala City?

    Yes, you’ll need a passport to travel to Guatemala City from Des Moines.

  • Which aircraft models fly most regularly from Des Moines to Guatemala City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Guatemala City?

    oneworld, and Star Alliance are the airline alliances operating flights between Des Moines and Guatemala City, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Guatemala City, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Guatemala City are United Airlines and American Airlines. With an average price for the route of $722 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $733 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Guatemala City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Guatemala City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Guatemala City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guatemala City from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Guatemala City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guatemala City with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and GUA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Guatemala City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guatemala City from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Guatemala City

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Guatemala City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Guatemala City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9768 reviews
7.3Comfort
8.1Crew
6.6Food
7.1Entertainment
7.7Boarding
Airline reviews

These airplanes should be illegal. The seats are two tight, it is a safety issue. Wheelchair support was ridiculously slow. We almost missed our flight.

4.0 OkayDenis, May 2026
SAV - ORD
Read more United Airlines reviews

These airplanes should be illegal. The seats are two tight, it is a safety issue. Wheelchair support was ridiculously slow. We almost missed our flight.

It was a short flight so I was expecting too much

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

I felt scammed. The priced advertised was different than what I paid. I paid the whole some online. I then got a call 20 minutes later saying I need to paid 70 more person. She said the price online is not the guaranteed price.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Easy of boarding, helpfully staff at check in, surprisingly comfortable seating

Check in was chaotic with only one counter for business class and first class. The luggage conveyor belt at JFK airport was broken so the flight departure was delayed which made the flight stressful as I had a tight connection. Although the captain said they could make up the delay, they didn’t do so.

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

Lost of requested seat assignments. Lost my husband's meal choice

Delayed delayed. Poor professionalism. Our seats changed and we pay for them

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

B-class on an old plane with antiquated amenities and poor service. Landed in Rome w/o bag that didn’t make the connection (plenty of time in London). Bag will come to hotel NOT the day it lands but the following night!! Still waiting for bag…BA had nothing to offer in support and couldn’t even tell me their comp, told to submit receipts and then I’ll learn what is or isn’t covered.

Movies on my phone are great. It would be nice to have a gluten free snack option.

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Awful, tons of delays, I got into Chicago multiple hours late meaning I hit the very traffic I tried so desperately to avoid. Just empty apologies from American Airlines text alerts. Trash behavior from a trash airline.

The flight attendants were very friendly, efficient, and helpful. The plane was ahead of schedule, and it all went very smoothly. Thank you.

Everything you need to know for your flight from Des Moines to Guatemala City

Information on your arrival and departure airports