DSM - GUA

$371 Find Cheap Flights from Des Moines to Guatemala City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Guatemala City departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$670
Typical prices: $557-$745
Multiple Airlines
Sun 1/17Sat 1/23
DSM - GUA • 1 stop
Cheapest one-way
$371
Multiple Airlines
Tue 9/1
DSM - GUA • 2 stops
Top airlines
Cheapest • from $715 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Nonstop flights
Not available
There are currently no direct flights between Des Moines and Guatemala City. You'll need at least 1 connection.
Insights
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Top layover airports
Cheapest • Avg $712 (round-trip)
Shortest trip • 6h 56m (one-way)
Insights
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Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
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Good to know
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We hope you love your trip to Guatemala City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Guatemala City (DSM-GUA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Guatemala City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Guatemala City

Sun, Jan 17 - Sat, Jan 23
Multiple Airlines Logo
6:15 am - 6:35 pmDSM  Des Moines-GUA Guatemala City La Aurora
12h 20m1 stop Chicago O'Hare Intl
Multiple Airlines Logo
5:25 am - 9:17 pmGUA  Guatemala City La Aurora-DSM Des Moines
15h 52m2 stops San Salvador El Salvador Intl Chicago O'Hare Intl
$670Multiple Airlines
Sun, Jan 17 - Sat, Jan 23
Multiple Airlines Logo
8:00 am - 6:25 pmDSM  Des Moines-GUA Guatemala City La Aurora
10h 25m2 stops Houston George Bush Intcntl San Salvador El Salvador Intl
Multiple Airlines Logo
6:55 am - 9:17 pmGUA  Guatemala City La Aurora-DSM Des Moines
14h 22m2 stops San Salvador El Salvador Intl Chicago O'Hare Intl
$672Multiple Airlines
Thu, Nov 26 - Mon, Dec 7
American Airlines Logo
7:26 pm - 3:19 pmDSM  Des Moines-GUA Guatemala City La Aurora
19h 53m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
1:40 pm - 12:25 amGUA  Guatemala City La Aurora-DSM Des Moines
10h 45m2 stops Miami Charlotte Douglas
$715American Airlines
Thu, Nov 26 - Mon, Dec 7
American Airlines Logo
7:26 pm - 3:19 pmDSM  Des Moines-GUA Guatemala City La Aurora
19h 53m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
3:09 pm - 10:48 pmGUA  Guatemala City La Aurora-DSM Des Moines
7h 39m1 stop Dallas/Fort Worth
$715American Airlines
Wed, Sep 16 - Wed, Sep 23
Multiple Airlines Logo
6:15 am - 6:30 pmDSM  Des Moines-GUA Guatemala City La Aurora
13h 15m2 stops Houston George Bush Intcntl San Salvador El Salvador Intl
Multiple Airlines Logo
5:25 am - 10:30 pmGUA  Guatemala City La Aurora-DSM Des Moines
16h 05m2 stops San Salvador El Salvador Intl Houston George Bush Intcntl
$721Multiple Airlines
Thu, Nov 26 - Mon, Dec 7
American Airlines Logo
3:31 pm - 12:09 pmDSM  Des Moines-GUA Guatemala City La Aurora
20h 38m2 stops Dallas/Fort Worth Miami
American Airlines Logo
11:33 am - 12:04 amGUA  Guatemala City La Aurora-DSM Des Moines
12h 31m2 stops Miami Chicago O'Hare Intl
$735American Airlines
Mon, Feb 1 - Sat, Feb 6
United Airlines Logo
8:00 am - 7:39 pmDSM  Des Moines-GUA Guatemala City La Aurora
11h 39m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
1:28 pm - 9:17 pmGUA  Guatemala City La Aurora-DSM Des Moines
7h 49m1 stop Chicago O'Hare Intl
$783United Airlines
Mon, Feb 1 - Sat, Feb 6
United Airlines Logo
8:00 am - 3:35 pmDSM  Des Moines-GUA Guatemala City La Aurora
7h 35m1 stop Houston George Bush Intcntl
United Airlines Logo
1:28 pm - 11:01 pmGUA  Guatemala City La Aurora-DSM Des Moines
9h 33m1 stop Chicago O'Hare Intl
$783United Airlines
Thu, Sep 10 - Thu, Sep 17
United Airlines Logo
6:15 am - 6:49 pmDSM  Des Moines-GUA Guatemala City La Aurora
13h 34m1 stop Houston George Bush Intcntl
United Airlines Logo
12:27 pm - 10:30 pmGUA  Guatemala City La Aurora-DSM Des Moines
9h 03m1 stop Houston George Bush Intcntl
$787United Airlines
Fri, Sep 18 - Fri, Sep 25
Delta Logo
5:45 am - 11:32 amDSM  Des Moines-GUA Guatemala City La Aurora
6h 47m1 stop Atlanta Hartsfield-Jackson
Delta Logo
1:02 pm - 10:26 pmGUA  Guatemala City La Aurora-DSM Des Moines
8h 24m1 stop Atlanta Hartsfield-Jackson
$837Delta
Booking Insights

KAYAK's insights & trends for Des Moines to Guatemala City flights

Get data-powered insights and trends into flights from Des Moines to Guatemala City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Guatemala City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Guatemala City departing in January.

Flight prices are typical for this route right now.

Flights to Guatemala City from Des Moines usually cost between $667 and $858 in January.
The lowest price found in the past 5 days was $670 on Multiple Airlines (Jan 17-Jan 23).

What is the cheapest month to fly from Des Moines to Guatemala City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Guatemala City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Guatemala City is September, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and July, where the average cost of round-trip tickets is $895 and $838 respectively.

Good to know

Low season

February

Cheapest flight

$371
Best time to beat the crowds with an average 35% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from Des Moines to Guatemala City

When to book flights from Des Moines to Guatemala City

Are your dates flexible? Find out the best times to travel from Des Moines to Guatemala City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Guatemala City

  • What is the cheapest flight from Des Moines to Guatemala City?

    In the last 5 days, the lowest price for a flight from Des Moines to Guatemala City was $371 for a one-way ticket and $670 for a round-trip.

  • Do I need a passport to fly between Des Moines and Guatemala City?

    Yes, you’ll need a passport to travel to Guatemala City from Des Moines.

  • Which aircraft models fly most regularly from Des Moines to Guatemala City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Guatemala City?

    oneworld, and Star Alliance are the airline alliances operating flights between Des Moines and Guatemala City, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Guatemala City, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Guatemala City are United Airlines and American Airlines. With an average price for the route of $722 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $686 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Guatemala City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Guatemala City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Guatemala City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guatemala City from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Guatemala City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guatemala City with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and GUA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Guatemala City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guatemala City from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Guatemala City

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Guatemala City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Guatemala City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10072 reviews
7.7Boarding
8.1Crew
7.3Comfort
6.7Food
7.1Entertainment
Airline reviews

Old 757 with poor entertainment system. United no longer partners with United for free text and email. O'Hara an absolute disaster! Limited gates clauses two hour delay. Unfortunately this appears to be the norm.

2.0 MediocreRichard, Aug 2026
Read more United Airlines reviews

Old 757 with poor entertainment system. United no longer partners with United for free text and email. O'Hara an absolute disaster! Limited gates clauses two hour delay. Unfortunately this appears to be the norm.

The flight to America was freezing. The overnight flight back to the UK was boiling hot and the cabin stank of toilet or occasionally perfume, even though I was several rows back from either bathroom. Food was tiny portions. Two small pieces of tough and dry beef in random gravy with pretend mashed potato raking up most of it. Very little veg. Salad was ok. Wooden cutlery broke within minutes of using. Lots of old films for entertainment. Some new ones. Generally a bit rubbish.

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

The Crew and the food was the worst I ever had in Business Class. First they told us there were no space for carry on. It was plenty of space over our 2 row seats, we had to ask to let us travel with it which was accepted. They were aware that we had to run for the connection due to the previous flight delay. Have us one hour waiting for more customers and not even offer a glass of water. Then started the service and they started to serve other passengers drinks in business and did not offer any drinks until they serve our pre ordered meal and I ask for something to drink. I had to wait until they finished to serve all passengers until Inget something. The crew was the worts I ever had for Business Class in my life.

Very rough getting into denver. my kid threw up it was so rough.

Flight delayed over 2 hours . I was flying bussiness never got food cause they ran out of what i wanted

Liked that we left on time for each flight. Snacks not the best, but we're okay.

I had requested wheelchair assistance prior to flight. The airport staff had no record of it. It was not provided at Cedar Rapids which was a small airport, so I managed on my own. At O'Hare airport the same thing happened. The staff told me they had no record of my request for a wheel chair. But they finally provided it after a delay when I insisted that I needed it.

It was very hot on the plane and it wasn’t acknowledged by the crew. This whole trip was one of the worst flying experiences I’ve had in a while. We sat in that hot plane on the tarmac in SLC for 45 min (after being delayed for 33 min for crew). 4 hours in the air in a barely cooled cabin. Over 30 min sitting on the tarmac in CLT waiting for a gate. I missed my original connection but was fortunate to get on the last flight out to RDU so I can make my 2 hour drive home. I know these things happen. But it’s frustrating nonetheless.

gate crew was courteous and helpful, flight attendant was nice and friendly once we got going. But we pushed off from the gate relatively on time, then sat there like 10 ft away, for an hour, with no announcement or explanation. Taxiing then took forever, and I get that there was runway congestion, but would be helpful to keep us posted on whats going on

There were alot of delays without any information. First, my original flight was overbooked so I volunteered to stay back. The layover was hell, I sat in the airport for 4 hours. I was highly disappointed because no one was around to provide answers.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.

Everything you need to know for your flight from Des Moines to Guatemala City

Information on your arrival and departure airports