$254 Find Cheap Flights from Des Moines to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Central America departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Des Moines to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$551
San José
San José1 stop$460
Guatemala City
Guatemala City2 stops$443
Panama City
Panama City2 stops$564
Liberia
Liberia1 stop$686
Managua
Managua2 stops$581
San Salvador
San Salvador1 stop$551
San José
San José1 stop$460
Guatemala City
Guatemala City2 stops$443
Panama City
Panama City2 stops$564
Liberia
Liberia1 stop$686
Managua
Managua2 stops$581

Book Cheap Des Moines to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Central America

Fri, May 8 - Sat, May 16
Multiple Airlines Logo
6:48 pm - 12:35 pm
DSM
-
GUA
18h 47m
2 stops
Multiple Airlines Logo
1:41 pm - 3:15 pm
GUA
-
DSM
24h 34m
1 stop
$443Multiple Airlines
Fri, May 8 - Sat, May 16
Multiple Airlines Logo
6:48 pm - 12:35 pm
DSM
-
GUA
18h 47m
2 stops
Multiple Airlines Logo
1:41 pm - 3:15 pm
GUA
-
DSM
24h 34m
1 stop
$446Multiple Airlines
Thu, May 7 - Thu, May 14
Multiple Airlines Logo
7:45 am - 11:33 am
DSM
-
SJO
28h 48m
1 stop
Multiple Airlines Logo
12:38 pm - 10:57 pm
SJO
-
DSM
33h 19m
2 stops
$460Multiple Airlines
Thu, Sep 17 - Wed, Sep 30
United Airlines Logo
3:00 pm - 8:49 pm
DSM
-
SAL
6h 49m
1 stop
United Airlines Logo
1:25 pm - 10:30 pm
SAL
-
DSM
8h 05m
1 stop
$561United Airlines
Fri, May 8 - Fri, May 15
American Airlines Logo
5:00 am - 12:40 pm
DSM
-
SAL
8h 40m
1 stop
American Airlines Logo
1:43 pm - 2:47 pm
SAL
-
DSM
24h 04m
1 stop
$562American Airlines
Thu, May 7 - Thu, May 14
American Airlines Logo
5:00 am - 12:40 pm
DSM
-
SAL
8h 40m
1 stop
American Airlines Logo
1:43 pm - 8:26 am
SAL
-
DSM
17h 43m
2 stops
$563American Airlines
Mon, Apr 20 - Thu, Apr 23
United Airlines Logo
8:20 am - 2:30 pm
DSM
-
SAL
7h 10m
1 stop
United Airlines Logo
3:40 pm - 2:19 pm
SAL
-
DSM
21h 39m
2 stops
$565United Airlines
Sat, May 23 - Wed, May 27
Copa Airlines Logo
6:00 am - 7:31 pm
DSM
-
PTY
13h 31m
1 stop
Copa Airlines Logo
7:55 am - 10:35 pm
PTY
-
DSM
14h 40m
1 stop
$583Copa Airlines
Mon, May 11 - Mon, May 18
Delta Logo
5:27 am - 11:31 am
DSM
-
GUA
7h 04m
1 stop
Delta Logo
1:01 pm - 10:32 pm
GUA
-
DSM
8h 31m
1 stop
$633Delta
Sun, May 3 - Wed, May 13
Delta Logo
5:45 pm - 11:56 am
DSM
-
SJO
19h 11m
2 stops
Delta Logo
1:20 pm - 10:32 pm
SJO
-
DSM
8h 12m
1 stop
$673Delta
Booking Insights

KAYAK's insights & trends for Des Moines to Central America flights

Get data-powered insights and trends into flights from Des Moines to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Central America is September, when tickets cost $483 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $1,408 and $798 respectively.

How far in advance should I book a flight from Des Moines to Central America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Central America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Central America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$254
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 34% increase in price.
Flight from Des Moines to Panama City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Des Moines to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Central America

 
Need help choosing which airline to fly with from Des Moines to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8327 reviews
8.5Crew
8.1Boarding
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

The cabin temperature was nice and cool. The wifi was not working.

8.0 ExcellentMatt, Mar 2026
SEA - SJC
Read more Delta reviews

The cabin temperature was nice and cool. The wifi was not working.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

As previously noted, this flight was great: departure was timely, the crew was friendly and attentive, and wifi connectivity was seamless. In particular, I appreciated that the flight attendant just told me to stow the laptop right before takeoff/landing, and trusted me to do so (which I did!).

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Entertainment is ok! Boarding and seat with zone is terrible. I paid for the seats but you didn’t give me what I paid for which is exit isles.

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

I will never fly ANA again. They lost one of my large pieces of checked luggage, the heaviest one with the most valuable items in it, and they said they will not send me an email unless they can't find it, even though the paper they gave me to track the status of my lost luggage requires a code from an email they are supposed to send me so I can do baggage tracing. They claim to be an international airline, but they also insist on calling a Japanese telephone number to confirm where to send the lost baggage if they find it. It is impossible to find an actual contact email address for customer support on their website, and their AI chatbot is unhelpful, directing you to a webpage that says it is for contact information but does not have any actual email addresses or phone numbers listed on it. My seat in economy did not recline at all, even though I was not sitting in an exit row nor the very back row. I had to sit in the fully upright position for over ten hours of international travel. Awful experience overall.

No seat back entertainment. And app had a hard time getting entertainment loaded.

ticket agent lady wás very helpful , she arranged wheel chair for my elderly mother

Didn't make the flight because the first leg of my flight was canceled and the next leg was already booked.

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Good quick flight on a small but comfortable plane. I'm 6'3 and had plenty of space.

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Business class seats felt very cramped compared to other airlines.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

Delays with no explanation. It could have been handled better.

Ceiling fell down and had to have maintenance come and duct tape it up. No WiFi on the flight.

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

The flight attendant was friendly and efficient. The temperature was kept nice and cool. The plane was nice, but filthy. There were visible spills on my tray table. The gate agent was somewhat rude with her announcements and in speaking with other customers.

I appreciate that I finally got the seat I paid extra for this time. Thank you

I would have liked a pillow. The vegetarian wrap and oaten cake was good.

I would have liked vegetarian and gluten free options for evening dinner time flight. I would have like a pillow on the international overnight flight . The veg wrap and oaten desert on the international flight was good

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports