$149 Find Cheap Flights from Des Moines to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Central America departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Des Moines to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$366
San José
San José1 stop$354
Guatemala City
Guatemala City2 stops$332
Panama City
Panama City1 stop$461
Liberia
Liberia2 stops$579
Managua
Managua1 stop$508
San Salvador
San Salvador1 stop$366
San José
San José1 stop$354
Guatemala City
Guatemala City2 stops$332
Panama City
Panama City1 stop$461
Liberia
Liberia2 stops$579
Managua
Managua1 stop$508

Book Cheap Des Moines to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Central America

Mon, Nov 3 - Wed, Nov 12
 Logo
8:00 am - 12:22 pmDSM-GUA
28h 22m2 stops
 Logo
1:22 pm - 10:00 amGUA-DSM
20h 38m1 stop
Mon, Nov 10 - Wed, Nov 19
 Logo
8:00 am - 12:26 pmDSM-GUA
28h 26m2 stops
 Logo
1:22 pm - 8:29 amGUA-DSM
19h 07m1 stop
Wed, Nov 19 - Wed, Nov 26
American Airlines Logo
6:00 am - 2:28 pmDSM-SAL
8h 28m1 stop
American Airlines Logo
1:20 pm - 11:33 pmSAL-DSM
10h 13m1 stop
$435American Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
American Airlines Logo
6:00 am - 2:28 pmDSM-SAL
8h 28m1 stop
American Airlines Logo
3:31 pm - 10:40 amSAL-DSM
19h 09m2 stops
$439American Airlines
Find Deal
Sun, Oct 12 - Wed, Oct 22
Delta Logo
5:47 am - 12:56 pmDSM-PTY
7h 09m1 stop
Delta Logo
2:21 pm - 10:30 pmPTY-DSM
8h 09m1 stop
$461Delta
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Sat, Oct 11 - Sat, Oct 18
United Airlines Logo
8:00 am - 6:37 pmDSM-PTY
10h 37m2 stops
United Airlines Logo
3:30 pm - 12:19 pmPTY-DSM
20h 49m2 stops
$466United Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
United Airlines Logo
8:02 am - 10:47 pmDSM-SAL
14h 45m2 stops
United Airlines Logo
6:55 am - 10:40 amSAL-DSM
27h 45m2 stops
$469United Airlines
Find Deal
Tue, Nov 25 - Thu, Dec 4
Delta Logo
5:52 pm - 2:12 pmDSM-PTY
19h 20m2 stops
Delta Logo
3:46 pm - 5:46 pmPTY-DSM
27h 00m1 stop
$475Delta
Find Deal
Wed, Oct 8 - Tue, Oct 14
Copa Airlines Logo
8:00 am - 10:24 amDSM-MGA
27h 24m3 stops
Copa Airlines Logo
3:12 am - 7:19 pmMGA-DSM
15h 07m2 stops
$629Copa Airlines
Find Deal
Sun, Oct 19 - Mon, Oct 27
Copa Airlines Logo
8:00 am - 10:24 amDSM-MGA
27h 24m3 stops
Copa Airlines Logo
3:12 am - 5:25 pmMGA-DSM
13h 13m2 stops
$1,329Copa Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to Central America flights

Get data-powered insights and trends into flights from Des Moines to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Central America is September, when tickets cost $526 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $1,490 and $832 respectively.

What’s the cheapest day of the week to fly from Des Moines to Central America?

The average price of all round-trip flights from Des Moines to Central America clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Central America on a Monday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Des Moines to Central America. For your return ticket, we recommend flying on a Thursday and avoiding Sundays for the best deals.

How far in advance should I book a flight from Des Moines to Central America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Central America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Central America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$149
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Des Moines to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Des Moines to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Central America?

    The cheapest time of day to fly to Central America is generally in the afternoon, when round-trip flights cost $553 on average. Morning departures are around 21% cheaper than evening flights, on average. The most expensive time of day to fly to Central America is generally in the evening, which is peak travel time and where the average cost of a ticket is $937.

Reviews of the top 3 airlines serving from Des Moines to Central America

 
Need help choosing which airline to fly with from Des Moines to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7960 reviews
7.9Comfort
8.2Boarding
7.9Entertainment
7.3Food
8.5Crew
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

The food was terrible especially for a 15 hour international flight. The crew was unpleasant as well.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

Everything was good, except the seats in economy were so close together, you could barely get out when the seat in front of your was reclined. If the airlines keep jamming in more and more seats, it will become intolerable. I will look for another airline that considers customer comfort and does not keep adding more rows of seats for more profit.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

IAD with the archaic people movers is just a place to be avoided.

Great service on board. Boarding a bit slow due to process. Food was pretty average.

Tastless food and too obvious lack of enthusiasm for service in the economy vesus business class

All of the United employees I interacted with were professional and courteous. The aircraft was clean, the food on the flight was good. No complaints here.

I had no checked baggage but was required to hand over carry on baggage at the door of the plane. There was a lot of overboard space in the plane and I was one of the last ones. I ran to get my carry on but it was gone. I was given back at the plane door in Toronto, so the wait was not as long as it would have been at the carousel.

Armrest controller on my seat 35D and nextbooennseat 35E did not work right. Hard to press buttons to recognize and 35D had constantnpressure either upmost down somit was nearly impossible to make selections. .

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

American airlines suck they delay the flights all the time made me sleep in an airport because my flight was delayed and I miss my connecting flight

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Don’t know they cancelled the flight day before I was to leave. They sent a email at 9:00 pm at night saying they cancelled. That is the smooth way to say we don’t want your business! I think they didn’t have enough people booking so they cancelled the flight! It’s all about the money anymore there is no honesty in business.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

It took way too long to diagnose and solve the problem of a broken crew member cabin seat. Though compensation for the volunteer who left the flight was very kind.

The entertainment package was vast and the selections were very current. Keep updating it was great.

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