$274 Find Cheap Flights from Des Moines to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Central America departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Des Moines to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$581
San José
San José1 stop$526
Guatemala City
Guatemala City2 stops$547
Panama City
Panama City1 stop$613
Liberia
Liberia2 stops$705
Managua
Managua2 stops$604
San Salvador
San Salvador1 stop$581
San José
San José1 stop$526
Guatemala City
Guatemala City2 stops$547
Panama City
Panama City1 stop$613
Liberia
Liberia2 stops$705
Managua
Managua2 stops$604

Book Cheap Des Moines to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Central America

Tue, May 26 - Mon, Jun 1
Multiple Airlines Logo
4:25 pm - 3:18 pm
DSM
-
SJO
23h 53m
1 stop
Multiple Airlines Logo
1:00 pm - 11:24 pm
SJO
-
DSM
9h 24m
1 stop
$526Multiple Airlines
Mon, Jun 1 - Mon, Jun 8
Multiple Airlines Logo
9:51 pm - 3:11 pm
DSM
-
SJO
42h 20m
2 stops
Multiple Airlines Logo
1:00 pm - 11:27 pm
SJO
-
DSM
9h 27m
1 stop
$528Multiple Airlines
Sun, May 17 - Wed, May 27
Multiple Airlines Logo
7:45 am - 3:18 pm
DSM
-
SJO
32h 33m
2 stops
Multiple Airlines Logo
7:00 am - 8:53 am
SJO
-
DSM
24h 53m
1 stop
$538Multiple Airlines
Wed, May 27 - Wed, Jun 3
United Airlines Logo
6:20 am - 8:49 pm
DSM
-
SAL
15h 29m
1 stop
United Airlines Logo
1:50 pm - 10:35 pm
SAL
-
DSM
7h 45m
1 stop
$581United Airlines
Wed, Jun 10 - Wed, Jun 24
United Airlines Logo
6:20 am - 8:49 pm
DSM
-
SAL
15h 29m
1 stop
United Airlines Logo
1:20 pm - 10:27 am
SAL
-
DSM
20h 07m
2 stops
$585United Airlines
Tue, May 26 - Tue, Jun 2
American Airlines Logo
5:50 am - 6:42 pm
DSM
-
SAL
13h 52m
1 stop
American Airlines Logo
7:00 am - 11:08 pm
SAL
-
DSM
15h 08m
1 stop
$589American Airlines
Thu, May 14 - Fri, May 22
American Airlines Logo
5:00 am - 12:40 pm
DSM
-
SAL
8h 40m
1 stop
American Airlines Logo
1:43 pm - 6:21 pm
SAL
-
DSM
27h 38m
1 stop
$591American Airlines
Mon, Aug 17 - Sun, Aug 30
Delta Logo
5:45 am - 12:04 pm
DSM
-
SAL
7h 19m
1 stop
Delta Logo
1:19 pm - 10:26 pm
SAL
-
DSM
8h 07m
1 stop
$611Delta
Fri, Jun 12 - Thu, Jun 25
Delta Logo
6:39 pm - 11:07 am
DSM
-
BZE
17h 28m
1 stop
Delta Logo
12:22 pm - 10:31 pm
BZE
-
DSM
9h 09m
1 stop
$645Delta
Tue, May 26 - Tue, Jun 9
Copa Airlines Logo
6:20 am - 6:37 pm
DSM
-
PTY
12h 17m
1 stop
Copa Airlines Logo
3:30 pm - 10:27 am
PTY
-
DSM
18h 57m
2 stops
$666Copa Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Central America flights

Get data-powered insights and trends into flights from Des Moines to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Central America is September, when tickets cost $483 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $1,343 and $742 respectively.

How far in advance should I book a flight from Des Moines to Central America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to Central America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to Central America, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 1 week before departure.

Good to know

Low seasonSeptember
Cheapest flight$274
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 30% increase in price.
Flight from Des Moines to Panama City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Des Moines to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Central America

 
Need help choosing which airline to fly with from Des Moines to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8438 reviews
7.9Comfort
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
Airline reviews

Everything was great. The only issue is unfixable. Seats are too small. 😁🤪

10.0 ExcellentAnonymous, Apr 2026
ATL - AMS
Read more Delta reviews

Everything was great. The only issue is unfixable. Seats are too small. 😁🤪

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Crew was nice, meal was good. Entertainment had to be rebooted 3 times and still did not work. Turns out there was residue on screen, it needed to be cleaned to prevent the touchscreen buttons from continuously activating. I had entertainment for the last 45 minutes of a 5 hour 45 minute flight. Really unacceptable for first class. Flight attendent indicated your cleaning solution creates this problem. Seems as if this is widely known, you should be using a different product or cleaning better. Really really disappointing which simply added to the wi fi on your planes with reliably never ever works.

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

Very old plane with no inflight entertainment. I purchased the internet pass and it was nearly unusable.

My tray was broken so i had no place to work or eat except my lap. Flight attendant said I would get an email with some credit or miles, it was a complete waste of time as I could only function at about 20% of normal. I have not received anything yet.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Flight itself excellent, but delayed so missed connection & got to destination 2 hrs later

The flight crew on this leg of my trip was very friendly and pleasant. Every one of them was humorous, as well as helpful and accommodating. This group was BY FAR the best crew I’ve flown with. They deserve kudos.

boarded early to only find out that flight would sit at gate for 45 min to an hour. Landed in chicago and sat on runway for over an hour before got to gate. Total delay was extensive for a 45 min flight door to door.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

The flight was significantly delayed. The inbound flight from EWR was delayed departing because of mechanical problems. My original departure from CLT was 5:28 pm but due to the delay of the inbound flight, after arrival, deplaning, cleaning, boarding, we did not push back from the gate until 9:00 pm. Once in the air, the flight was smooth and what was originally supposed to be an arrival in ORD at 7:30 pm local time turned out to be 9:35 pm.

Putting people that close to the bathroom, where you have to look into the bathroom as people are exiting and entering was not great and the smell was also not great. I know the airlines are desperate for more chairs, but that seat is a crime.

My bags were misplaced!!! Im in a foreign country with no bags

Overall a good experience, however Wifi was not working on the flight.

For a 4 1/2 hour international flight all we got was 1 small pack of cookies and a drink. You had to watch movies on your own devise.

Airlines should be prohibited from using the seats they get away with.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Returned home with a blood clot from flight homes and the uncomfortable aircraft I was on.

Original flight was on time, then late, then changed gates...4 times. Once our newest plane came in, it was fine.

The crew was very kind, but no in-flight entertainment monitors and a 2 hour and 30 minute delay was extremely frustrating.

Everything was delayed and the staff sent me to the wrong gate, causing me to miss one of my flights. I arrived at my destination 6 hours later than I was supposed to.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports