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Flight Deals
Book Cheap Des Moines to Guatemala Plane Tickets
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Guatemala that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Recent round-trip flight deals from Des Moines to Guatemala
Fri, Jan 22 - Fri, Jan 29
8:00 am - 6:50 pmDSM Des Moines-GUA Guatemala City La Aurora
10h 50m1 stop Chicago O'Hare Intl
8:05 am - 9:23 pmGUA Guatemala City La Aurora-DSM Des Moines
13h 18m1 stop Chicago O'Hare Intl
$583Multiple Airlines
Fri, Jan 22 - Fri, Jan 29
7:41 am - 11:21 pmDSM Des Moines-GUA Guatemala City La Aurora
15h 40m2 stops Chicago O'Hare Intl Dallas/Fort Worth
6:50 am - 11:03 pmGUA Guatemala City La Aurora-DSM Des Moines
16h 13m2 stops Dallas/Fort Worth Charlotte Douglas
$674American Airlines
Fri, Jan 22 - Fri, Jan 29
10:57 am - 11:21 pmDSM Des Moines-GUA Guatemala City La Aurora
12h 24m2 stops Charlotte Douglas Dallas/Fort Worth
6:50 am - 5:29 pmGUA Guatemala City La Aurora-DSM Des Moines
10h 39m1 stop Dallas/Fort Worth
$674American Airlines
Fri, Jan 15 - Mon, Feb 1
3:31 pm - 11:21 pmDSM Des Moines-GUA Guatemala City La Aurora
7h 50m1 stop Dallas/Fort Worth
1:12 pm - 10:16 pmGUA Guatemala City La Aurora-DSM Des Moines
9h 04m1 stop Dallas/Fort Worth
$712American Airlines
Wed, Nov 18 - Wed, Dec 2
8:00 am - 11:05 pmDSM Des Moines-GUA Guatemala City La Aurora
15h 05m2 stops Houston George Bush Intcntl San Salvador El Salvador Intl
8:05 am - 9:25 pmGUA Guatemala City La Aurora-DSM Des Moines
13h 20m1 stop Chicago O'Hare Intl
$782Multiple Airlines
Wed, Nov 18 - Wed, Dec 2
8:00 am - 11:05 pmDSM Des Moines-GUA Guatemala City La Aurora
15h 05m2 stops Houston George Bush Intcntl San Salvador El Salvador Intl
8:05 am - 9:25 pmGUA Guatemala City La Aurora-DSM Des Moines
13h 20m1 stop Chicago O'Hare Intl
$782Multiple Airlines
Tue, Dec 1 - Tue, Dec 8
3:20 pm - 5:50 amDSM Des Moines-GUA Guatemala City La Aurora
38h 30m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
8:05 am - 5:14 pmGUA Guatemala City La Aurora-DSM Des Moines
9h 09m1 stop Chicago O'Hare Intl
$787Avianca
Sat, Apr 10 - Wed, Apr 14
5:00 am - 8:30 pmDSM Des Moines-GUA Guatemala City La Aurora
16h 30m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
12:27 pm - 10:30 pmGUA Guatemala City La Aurora-DSM Des Moines
9h 03m1 stop Houston George Bush Intcntl
$857United Airlines
Sat, Apr 10 - Wed, Apr 14
5:00 am - 4:37 pmDSM Des Moines-GUA Guatemala City La Aurora
12h 37m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
3:45 pm - 10:20 amGUA Guatemala City La Aurora-DSM Des Moines
17h 35m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$857United Airlines
Sat, Apr 10 - Wed, Apr 14
6:15 am - 4:37 pmDSM Des Moines-GUA Guatemala City La Aurora
11h 22m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
3:45 pm - 10:20 amGUA Guatemala City La Aurora-DSM Des Moines
17h 35m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$870United Airlines
Recent one-way flight deals from Des Moines to Guatemala
Thu, Nov 26
8:28 pm - 8:49 pmDSM Des Moines-GUA Guatemala City La Aurora
24h 21m2 stops Denver Intl Mexico City Benito Juarez
$249Multiple Airlines
Mon, Jan 11
11:12 am - 8:49 pmDSM Des Moines-GUA Guatemala City La Aurora
33h 37m3 stops Nashville Intl Denver Intl Mexico City Benito Juarez
$257Multiple Airlines
Mon, Jan 11
8:00 am - 6:50 pmDSM Des Moines-GUA Guatemala City La Aurora
10h 50m1 stop Chicago O'Hare Intl
$276Multiple Airlines
Fri, Jan 29
8:00 am - 6:50 pmDSM Des Moines-GUA Guatemala City La Aurora
10h 50m1 stop Chicago O'Hare Intl
$280Multiple Airlines
Fri, Jan 29
6:00 am - 8:59 pmDSM Des Moines-GUA Guatemala City La Aurora
14h 59m2 stops Dallas/Fort Worth Miami
$311American Airlines
Mon, Jan 11
3:31 pm - 12:11 pmDSM Des Moines-GUA Guatemala City La Aurora
20h 40m2 stops Dallas/Fort Worth Miami
$323American Airlines
Fri, Jan 1
6:00 am - 11:00 pmDSM Des Moines-GUA Guatemala City La Aurora
17h 00m1 stop Houston George Bush Intcntl
$364United Airlines
Sat, Jan 9
11:06 am - 10:25 pmDSM Des Moines-GUA Guatemala City La Aurora
11h 19m2 stops Chicago O'Hare Intl Miami
$374American Airlines
Wed, Nov 18
6:05 am - 7:39 pmDSM Des Moines-GUA Guatemala City La Aurora
13h 34m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$521United Airlines
Thu, Nov 26
8:00 am - 7:39 pmDSM Des Moines-GUA Guatemala City La Aurora
11h 39m1 stop Houston George Bush Intcntl
$531United Airlines
Recent last minute flight deals from Des Moines to Guatemala
Fri, Nov 6 - Mon, Nov 23
8:10 am - 10:36 pmDSM Des Moines-GUA Guatemala City La Aurora
14h 26m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth
4:15 pm - 9:01 amGUA Guatemala City La Aurora-DSM Des Moines
16h 46m2 stops Miami Chicago O'Hare Intl
$923American Airlines
Fri, Nov 6 - Sun, Nov 22
6:45 pm - 1:46 pmDSM Des Moines-GUA Guatemala City La Aurora
19h 01m1 stop Chicago O'Hare Intl
1:05 am - 5:28 pmGUA Guatemala City La Aurora-DSM Des Moines
16h 23m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$960United Airlines
Fri, Nov 6 - Mon, Nov 23
9:37 am - 10:36 pmDSM Des Moines-GUA Guatemala City La Aurora
12h 59m1 stop Dallas/Fort Worth
1:04 pm - 9:07 amGUA Guatemala City La Aurora-DSM Des Moines
20h 03m1 stop Dallas/Fort Worth
$1,231American Airlines
Booking Insights
Price, demand and travel trends for Des Moines to Guatemala flights
Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.
Prices
Airlines
More
What are the cheapest fares from Des Moines to Guatemala right now?
The cheapest fare from Des Moines to Guatemala in the last week was $583 round-trip, to Guatemala City La Aurora (GUA).
Which airport in Guatemala is the cheapest to fly to from Des Moines?
All flights from Des Moines to Guatemala arrive at Guatemala City La Aurora (GUA). On average, round-trip fares are around $754.
What’s the cheapest day to fly from Des Moines to Guatemala?
Wednesday tends to be the cheapest day to fly from Des Moines to Guatemala, while Monday is the most expensive. Fares run about 27% higher that day, based on the past 12 months of KAYAK data.
What's the cheapest time of day to fly from Des Moines to Guatemala?
Data from the past 12 months shows it's cheapest to fly to Guatemala during the afternoon with average prices of $670. The morning is the most expensive time to fly, with average prices of $792.
What are the cheapest airlines to fly with from Des Moines to Guatemala?
Fares reflect aggregated pricing data and may not include every trip type.
Looking at KAYAK data from the last 12 months, the cheapest airlines to fly with from Des Moines to Guatemala are:
• United Airlines (avg. price $724)
• American Airlines (avg. price $741)
• Delta (avg. price $755)
• JetBlue (avg. price $885)
• GOL (avg. price $1,692)
What's the most popular airline to fly with from Des Moines to Guatemala?
Drawing on KAYAK data from the past three months, the most popular airlines to fly with from Des Moines to Guatemala are:
• United Airlines
• American Airlines
• Delta
What are the most popular flight destinations in Guatemala?
Guatemala City is the most popular flight destination in Guatemala, based on KAYAK data from the past 3 months.
Key details for Des Moines to Guatemala flights
Low season | September |
|---|---|
High season | January |
Cheapest flight | $249 |
Your Des Moines to Guatemala flight questions, answered
Find helpful answers about this route, including flight times, airports, airlines and booking tips.
Your guide to booking Des Moines to Guatemala flights
Get tips on when to book, when to fly and what to know before your trip.Reviews of the top 3 airlines serving from Des Moines to Guatemala
7.8
DeltaOverall score based on 8697 reviews
7.8Entertainment
7.8Comfort
8.1Boarding
8.5Crew
7.2Food
Airline reviews
Great overall experience and use of the Delta One lounge was amazing!
10.0 ExcellentAvery, Nov 2026
Great overall experience and use of the Delta One lounge was amazing!
I used by Skymiles to upgrade to First so that I could comfortably work using my laptop. But WiFi was intermittent and unavailable for long periods. I feel like I wasted 70,000 miles :(
Great as one can be for a one connection 6 hour flight
Packed flight and not sure why dinner service would start at midnight while passengers we’re trying to sleep
The gate attendant was not clear w message on flight delays.
Chairs don’t recline and the ones that do recline, barely do recline. It was most uncomfortable flight i ever been on.
Good but not on par when compared with foreign flag carriers.
Good service but not on par when compared to foreign flag carriers.
Mechanical delay of 2 hours without telling us Canadians of the potential compensation for this delay. As this caused 2 out of three people in our travelling party to miss their connecting flights until the next day.
I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.
1 person checking us as we boarded, left gate on time, 12.30 we are told we were held for 15 mins as other flights were waiting to take off, captain due to rain … they were having a longer gap between take offs , 3pm we took off , they went land route via New Orleans in to Florida landed at 5.45pm offered coffee and a biscuit
Service was slow Flight was very loud at back of plane
1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding
It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.
Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.
The Crew and the food was the worst I ever had in Business Class. First they told us there were no space for carry on. It was plenty of space over our 2 row seats, we had to ask to let us travel with it which was accepted. They were aware that we had to run for the connection due to the previous flight delay. Have us one hour waiting for more customers and not even offer a glass of water. Then started the service and they started to serve other passengers drinks in business and did not offer any drinks until they serve our pre ordered meal and I ask for something to drink. I had to wait until they finished to serve all passengers until Inget something. The crew was the worts I ever had for Business Class in my life.
Very rough getting into denver. my kid threw up it was so rough.
Flight delayed over 2 hours . I was flying bussiness never got food cause they ran out of what i wanted
Liked that we left on time for each flight. Snacks not the best, but we're okay.
I had requested wheelchair assistance prior to flight. The airport staff had no record of it. It was not provided at Cedar Rapids which was a small airport, so I managed on my own. At O'Hare airport the same thing happened. The staff told me they had no record of my request for a wheel chair. But they finally provided it after a delay when I insisted that I needed it.
The flight was delayed several times as they didn't have pilots. Then we were boarded on the plane and again waited on the tarmac for over 30-40 minutes waiting for pilots to board. The in flight entertainment was confusing at best on how to use it. It took multiple attempts to get wifi to connect and by the time it worked the flight was almost over.
The flight was delayed and gate changed so that was not fun and the flight to Dallas from LAX was very delayed on Sunday. It was just not a great experience due to the delays both ways.
Fine. No announcement for Concierge Key to board. Not a big issue just pointing it out.
The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.
The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.
In flight connectivity (via T-Mobile) was often not working.
Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.
It was exactly what I expected, actually arriving sooner than scheduled.
Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.
Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.
More options for your flight from Des Moines to Guatemala
Complete your trip to Guatemala with a hotel stay or car rental
Information on your arrival and departure airports
Cabin class types available on flights to Guatemala
Cabin classes available on flights to Guatemala. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from other airports in Des Moines to Guatemala
Flights from all airports in Des Moines to Guatemala. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.