Find Deals on Flights from Des Moines to Greenville (DSM - GSP)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Greenville

(Round-trip)
Depart: Tue Mar 21 2017 Return: Wed Mar 22 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
9:23a
GSP
1:31p
4h 08m
1 stop
GSP
3:57a
DSM
9:57a
6h 00m
1 stop
Depart: Mon Apr 3 2017 Return: Fri Apr 7 2017 Trip spans 5 days
Major Airline
Major Airline
DSM
1:00a
GSP
1:32a
0h 32m
1 stop
GSP
1:00a
DSM
3:32a
2h 32m
1 stop
Depart: Wed Mar 22 2017 Return: Thu Mar 23 2017 Trip spans 2 days
Delta
Delta
DSM
7:25a
GSP
1:24p
5h 59m
1 stop
GSP
12:15p
DSM
7:15p
7h 00m
1 stop
Depart: Tue Apr 4 2017 Return: Wed Apr 5 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
9:19a
GSP
1:32p
4h 13m
1 stop
GSP
4:00a
DSM
9:57a
5h 57m
1 stop
Depart: Mon Mar 27 2017 Return: Fri Mar 31 2017 Trip spans 5 days
Major Airline
Major Airline
DSM
1:00a
GSP
1:32a
0h 32m
1 stop
GSP
1:00a
DSM
3:32a
2h 32m
1 stop
Depart: Wed Mar 29 2017 Return: Thu Mar 30 2017 Trip spans 2 days
Delta
Delta
DSM
2:35a
GSP
6:58a
4h 23m
1 stop
GSP
1:40a
DSM
7:50a
6h 10m
1 stop
Depart: Mon Mar 20 2017 Return: Wed Mar 22 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
11:25a
GSP
5:50p
6h 25m
1 stop
GSP
3:57a
DSM
9:57a
6h 00m
1 stop
Depart: Sat Apr 1 2017 Return: Thu Apr 6 2017 Trip spans 6 days
Delta
Delta
DSM
1:45a
GSP
6:28a
4h 43m
1 stop
GSP
6:16a
DSM
1:30p
7h 14m
1 stop
Depart: Wed Apr 5 2017 Return: Thu Apr 6 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
9:37a
GSP
5:14p
7h 37m
1 stop
GSP
4:00a
DSM
9:57a
5h 57m
1 stop
Depart: Mon Mar 13 2017 Return: Wed Mar 15 2017 Trip spans 3 days
Delta
Delta
DSM
1:09p
GSP
7:30p
6h 21m
1 stop
GSP
1:40a
DSM
7:50a
6h 10m
1 stop
Depart: Tue Apr 18 2017 Return: Mon Apr 24 2017 Trip spans 7 days
Major Airline
Major Airline
DSM
2:00a
GSP
2:32a
0h 32m
nonstop
GSP
2:00a
DSM
4:32a
2h 32m
nonstop
Depart: Sun Mar 19 2017 Return: Wed Mar 22 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
11:25a
GSP
3:56p
4h 31m
1 stop
GSP
3:57a
DSM
9:57a
6h 00m
1 stop
Depart: Sun Apr 2 2017 Return: Thu Apr 6 2017 Trip spans 5 days
Delta
Delta
DSM
1:10p
GSP
5:50p
4h 40m
1 stop
GSP
12:20p
DSM
6:54p
6h 34m
1 stop
Depart: Sun Mar 26 2017 Return: Tue Mar 28 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
8:45a
GSP
3:56p
7h 11m
2 stops
GSP
2:00a
DSM
8:36a
6h 36m
2 stops
Depart: Thu Jun 8 2017 Return: Tue Jun 13 2017 Trip spans 6 days
Delta
Delta
DSM
1:58a
GSP
6:19a
4h 21m
1 stop
GSP
3:00p
DSM
7:07p
4h 07m
1 stop
Depart: Fri Mar 17 2017 Return: Thu Mar 23 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
5:40a
GSP
3:56p
10h 16m
2 stops
GSP
2:00a
DSM
8:36a
6h 36m
2 stops
Depart: Sat Mar 25 2017 Return: Tue Mar 28 2017 Trip spans 4 days
Delta
Delta
DSM
1:50a
GSP
6:18a
4h 28m
1 stop
GSP
12:15p
DSM
7:15p
7h 00m
1 stop
Depart: Fri Mar 31 2017 Return: Tue Apr 4 2017 Trip spans 5 days
Delta
Delta
DSM
1:09p
GSP
7:30p
6h 21m
1 stop
GSP
2:59p
DSM
7:45p
4h 46m
1 stop
Depart: Sat Mar 18 2017 Return: Wed Mar 22 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GSP
7:29a
4h 29m
1 stop
GSP
3:57a
DSM
9:57a
6h 00m
1 stop
Depart: Thu Apr 6 2017 Return: Mon Apr 10 2017 Trip spans 5 days
Delta
Delta
DSM
1:10p
GSP
5:50p
4h 40m
1 stop
GSP
2:59p
DSM
7:45p
4h 46m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$278
Destination

Greenville
$278