Find Deals on Flights from Des Moines to Knoxville McGhee Tyson (DSM - TYS)

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Knoxville McGhee Tyson

(Round-trip)
Depart: Fri Mar 31 2017 Return: Mon Apr 3 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
11:25a
TYS
3:45p
4h 20m
1 stop
TYS
12:27p
DSM
7:14p
6h 47m
1 stop
Depart: Thu Mar 30 2017 Return: Sun Apr 2 2017 Trip spans 4 days
Delta
Delta
DSM
2:35a
TYS
6:53a
4h 18m
1 stop
TYS
1:45a
DSM
7:54a
6h 09m
1 stop
Depart: Tue Mar 14 2017 Return: Wed Mar 15 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
11:25a
TYS
6:39p
7h 14m
1 stop
TYS
1:55p
DSM
6:22p
4h 27m
1 stop
Depart: Wed Mar 8 2017 Return: Tue Mar 14 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
4:40a
TYS
1:42p
9h 02m
2 stops
TYS
7:40a
DSM
11:42a
4h 02m
1 stop
Depart: Sun Mar 12 2017 Return: Wed Mar 15 2017 Trip spans 4 days
Delta
Delta
DSM
10:38a
TYS
6:02p
7h 24m
1 stop
TYS
3:42a
DSM
11:23a
7h 41m
1 stop
Depart: Thu Apr 20 2017 Return: Sun Apr 23 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
9:19a
TYS
2:30p
5h 11m
1 stop
TYS
3:10a
DSM
9:49a
6h 39m
1 stop
Depart: Mon Mar 13 2017 Return: Thu Mar 16 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
11:25a
TYS
6:39p
7h 14m
1 stop
TYS
7:40a
DSM
11:42a
4h 02m
1 stop
Depart: Thu Mar 9 2017 Return: Tue Mar 14 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
4:40a
TYS
2:45p
10h 05m
2 stops
TYS
7:40a
DSM
11:42a
4h 02m
1 stop
Depart: Fri Mar 10 2017 Return: Mon Mar 13 2017 Trip spans 3 days
Delta
Delta
DSM
9:55a
TYS
5:02p
7h 07m
1 stop
TYS
1:15p
DSM
6:04p
4h 49m
1 stop
Depart: Sat Mar 11 2017 Return: Tue Mar 14 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
8:37a
TYS
4:07p
7h 30m
1 stop
TYS
7:40a
DSM
11:42a
4h 02m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$396
Destination

Knoxville
$396