DSM - ROA

$309 Find Cheap Flights from Des Moines to Roanoke - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Roanoke departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$309
Typical prices: $308-$402
American Airlines
Wed 9/30Sat 10/3
DSM - ROA • 1 stop
Cheapest one-way
$419
American Airlines
Thu 7/9
DSM - ROA • 1 stop
Top airlines
Cheapest • from $309 (round-trip)
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
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Nonstop flights
Not available
There are currently no direct flights between Des Moines and Roanoke. You'll need at least 1 connection.
Insights
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Top layover airports
Cheapest • Avg $278 (round-trip)
Shortest trip • 4h 47m (one-way)
Insights
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Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
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+1
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We hope you love your trip to Roanoke!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Roanoke (DSM-ROA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Roanoke that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Roanoke

Wed, Sep 30 - Sat, Oct 3
American Airlines Logo
1:30 pm - 7:48 pm
DSM
-
ROA
5h 18m
1 stop
American Airlines Logo
1:57 pm - 7:51 pm
ROA
-
DSM
6h 54m
1 stop
$309American Airlines
Wed, Sep 30 - Sat, Oct 3
American Airlines Logo
8:03 am - 1:26 pm
DSM
-
ROA
4h 23m
1 stop
American Airlines Logo
3:27 pm - 12:04 am
ROA
-
DSM
9h 37m
2 stops
$314American Airlines
Tue, Jul 14 - Sat, Jul 18
American Airlines Logo
1:41 pm - 9:20 pm
DSM
-
ROA
6h 39m
1 stop
American Airlines Logo
7:53 pm - 12:09 am
ROA
-
DSM
5h 16m
1 stop
$339American Airlines
Tue, Jul 14 - Sat, Jul 18
American Airlines Logo
1:35 pm - 11:59 pm
DSM
-
ROA
9h 24m
2 stops
American Airlines Logo
7:53 pm - 12:09 am
ROA
-
DSM
5h 16m
1 stop
$344American Airlines
Tue, Aug 25 - Sat, Aug 29
United Airlines Logo
3:20 pm - 8:59 pm
DSM
-
ROA
4h 39m
1 stop
United Airlines Logo
5:50 pm - 9:23 pm
ROA
-
DSM
4h 33m
1 stop
$389United Airlines
Tue, Aug 25 - Sat, Aug 29
United Airlines Logo
6:00 am - 2:18 pm
DSM
-
ROA
7h 18m
2 stops
United Airlines Logo
5:50 pm - 9:23 pm
ROA
-
DSM
4h 33m
1 stop
$394United Airlines
Wed, Sep 30 - Sat, Oct 3
United Airlines Logo
6:00 am - 2:14 pm
DSM
-
ROA
7h 14m
2 stops
United Airlines Logo
6:49 am - 4:20 pm
ROA
-
DSM
10h 31m
2 stops
$398United Airlines
Tue, Aug 25 - Sat, Aug 29
United Airlines Logo
8:00 am - 7:07 pm
DSM
-
ROA
10h 07m
2 stops
United Airlines Logo
10:44 am - 8:26 pm
ROA
-
DSM
10h 42m
2 stops
$399United Airlines
Fri, Jul 17 - Tue, Jul 21
American Airlines Logo
5:00 am - 2:42 pm
DSM
-
ROA
8h 42m
2 stops
American Airlines Logo
2:51 pm - 12:01 am
ROA
-
DSM
10h 10m
2 stops
$409American Airlines
Sat, Sep 19 - Sun, Sep 20
United Airlines Logo
6:29 am - 1:54 pm
DSM
-
ROA
6h 25m
2 stops
United Airlines Logo
6:40 am - 10:31 am
ROA
-
DSM
4h 51m
1 stop
$424United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Roanoke flights

Get data-powered insights and trends into flights from Des Moines to Roanoke to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Roanoke?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Roanoke, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Roanoke is March, where tickets cost $0 (return) on average. On the other hand, the most expensive months are July and June, where the average cost of round-trip tickets is $750 and $448 respectively.

Good to know

Low seasonSeptember
Cheapest flight$309
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Des Moines to Roanoke

When to book flights from Des Moines to Roanoke

Are your dates flexible? Find out the best times to travel from Des Moines to Roanoke based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Roanoke

  • What is the cheapest flight from Des Moines to Roanoke?

    In the last 5 days, the lowest price for a flight from Des Moines to Roanoke was $419 for a one-way ticket and $309 for a round-trip.

  • Do I need a passport to fly between Des Moines and Roanoke?

    No, a passport isn't needed to fly from Des Moines to Roanoke. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Des Moines to Roanoke?

    Des Moines and Roanoke are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Roanoke.

  • Which aircraft models fly most regularly from Des Moines to Roanoke?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Roanoke?

    oneworld is the only airline alliance operating flights between Des Moines and Roanoke.

  • How does KAYAK find such low prices on flights from Des Moines to Roanoke?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Roanoke.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Roanoke?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Roanoke from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Roanoke?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Roanoke with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and ROA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Roanoke?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Roanoke from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Roanoke

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Roanoke. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Roanoke? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11766 reviews
6.8Entertainment
7.5Boarding
7.2Comfort
6.4Food
7.9Crew
Airline reviews

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

8.0 ExcellentSteven, Jan 2026
CID - PHX
Read more American Airlines reviews

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Flight was delayed , waited in the tarmac for 3 hours and then came back and was cancelled

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed almost 4 hours for a 45 minute flight with no explanation.

The flight was excellent, provided that we had inclement weather. We departed earlier than scheduled and arrived early. There was a little turbulence, but nothing to be worried about.

I disliked that I didn’t have a flight today, not entirely sure why I’m being asked

Everything you need to know for your flight from Des Moines to Roanoke

Information on your arrival and departure airports