DSM - ROA

$240 Find Cheap Flights from Des Moines to Roanoke

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Roanoke departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Roanoke

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Roanoke, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Roanoke, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$328
Typical prices: $362-$318
American Airlines
Wed 5/6Wed 5/13
DSM - ROA • 1 stop
Cheapest one-way
$240
American Airlines
Wed 4/15
DSM - ROA • 1 stop
Top airlines
Cheapest • from $328 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Roanoke. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $265 (round-trip)
Shortest trip • 4h 51m (one-way)
Insights
Insights
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Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Roanoke!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Roanoke (DSM-ROA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Roanoke that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Roanoke

Wed, May 6 - Wed, May 13
American Airlines Logo
2:02 pm - 9:26 pm
DSM
-
ROA
6h 24m
1 stop
American Airlines Logo
7:28 am - 1:46 pm
ROA
-
DSM
7h 18m
1 stop
$328American Airlines
Sat, May 16 - Sat, May 23
American Airlines Logo
5:01 pm - 12:14 am
DSM
-
ROA
6h 13m
1 stop
American Airlines Logo
8:55 am - 12:52 pm
ROA
-
DSM
4h 57m
1 stop
$329American Airlines
Wed, May 6 - Wed, May 13
American Airlines Logo
8:56 am - 5:33 pm
DSM
-
ROA
7h 37m
2 stops
American Airlines Logo
7:28 am - 1:46 pm
ROA
-
DSM
7h 18m
1 stop
$333American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
5:01 pm - 12:10 am
DSM
-
ROA
6h 09m
1 stop
American Airlines Logo
7:28 am - 1:46 pm
ROA
-
DSM
7h 18m
1 stop
$339American Airlines
Wed, Apr 8 - Sun, Apr 12
American Airlines Logo
8:56 am - 5:33 pm
DSM
-
ROA
7h 37m
2 stops
American Airlines Logo
7:28 am - 1:46 pm
ROA
-
DSM
7h 18m
1 stop
$344American Airlines
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
3:00 pm - 10:26 pm
DSM
-
ROA
6h 26m
1 stop
American Airlines Logo
7:28 am - 1:46 pm
ROA
-
DSM
7h 18m
1 stop
$359American Airlines
Thu, Jul 2 - Sun, Jul 5
Delta Logo
6:39 pm - 12:29 am
DSM
-
ROA
4h 50m
1 stop
Delta Logo
6:00 am - 10:55 am
ROA
-
DSM
5h 55m
1 stop
$384Delta
Fri, Apr 17 - Mon, Apr 20
United Airlines Logo
3:21 pm - 9:07 pm
DSM
-
ROA
4h 46m
1 stop
United Airlines Logo
5:45 pm - 9:32 pm
ROA
-
DSM
4h 47m
1 stop
$389United Airlines
Fri, Apr 17 - Mon, Apr 20
United Airlines Logo
7:16 pm - 12:37 am
DSM
-
ROA
4h 21m
1 stop
United Airlines Logo
2:55 pm - 9:32 pm
ROA
-
DSM
7h 37m
2 stops
$395United Airlines
Fri, Apr 17 - Mon, Apr 20
United Airlines Logo
7:16 pm - 12:37 am
DSM
-
ROA
4h 21m
1 stop
United Airlines Logo
2:55 pm - 11:17 pm
ROA
-
DSM
9h 22m
2 stops
$400United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Roanoke flights

Get data-powered insights and trends into flights from Des Moines to Roanoke to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Roanoke?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Roanoke departing in May.

Good to know

Low seasonJune
Cheapest flight$240
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Des Moines to Roanoke

When to book flights from Des Moines to Roanoke

Are your dates flexible? Find out the best times to travel from Des Moines to Roanoke based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Roanoke

  • What is the cheapest flight from Des Moines to Roanoke?

    In the last 3 days, the lowest price for a flight from Des Moines to Roanoke was $240 for a one-way ticket and $328 for a round-trip.

  • Do I need a passport to fly between Des Moines and Roanoke?

    No, a passport isn't needed to fly from Des Moines to Roanoke. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Des Moines to Roanoke?

    Des Moines and Roanoke are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Roanoke.

  • Which aircraft models fly most regularly from Des Moines to Roanoke?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Roanoke?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Roanoke, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Roanoke, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Roanoke are Delta and American Airlines. With an average price for the route of $318 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $338 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Roanoke?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Roanoke.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Roanoke?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Roanoke from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Roanoke?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Roanoke with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and ROA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Roanoke?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Roanoke from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Roanoke

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Roanoke. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Roanoke? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8341 reviews
8.1Boarding
7.8Entertainment
8.5Crew
7.9Comfort
7.2Food
Airline reviews

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

2.0 MediocreAliya, Mar 2026
JFK - ATL
Read more Delta reviews

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

I am still at the Airport! Delayed Delayed and Delyaed

I took seat 15A in anticipation of window seat, there is no window.

The first class flight attendant was awful to everyone. Very rude; no customer service. She should not be working in first class.

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

It was fine. 55 minute flight. No snacks or beverage service offered. Boarding went smoothly and my walker was waiting for me on the jet way.

Smaller plane for a longer flight than my first one. Doesn’t make sense.

The cabin temperature was nice and cool. The wifi was not working.

The flight changed gates multiple times and flight had to be delayed multiple times

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

Delayed for mechanical and no updates on what was happening and how long the delay might be.

My flight from LGA was cancelled and my rebooked flight from JFK was delayed numerous times. I will now be getting home after 2am.

Flight was delayed half hour before boarding, but when I checked flight aware the plane that would Pick us up had a delay of more than an hour. AA should let us know in advance to avoid waiting several hours in the airport

On the return flight, arriving in Denver we sat on the tarmac in Denver for over 20 minutes.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The flight attendant in business class was excellent! Professional, friendly and attentive.

Delays with no explanation. It could have been handled better.

Everything you need to know for your flight from Des Moines to Roanoke

Information on your arrival and departure airports