DSM - ROA

$222 Find Cheap Flights from Des Moines to Roanoke

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Roanoke departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Roanoke

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Roanoke, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Roanoke, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$269
Delta
Sat 5/16Sat 5/23
DSM - ROA • 1 stop
Cheapest one-way
$222
American Airlines
Tue 5/19
DSM - ROA • 1 stop
Top airlines
Delta
Cheapest • from $269 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Roanoke!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Roanoke (DSM-ROA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Roanoke that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Roanoke

Sat, May 16 - Sat, May 23
Delta Logo
6:41 pm - 12:34 am
DSM
-
ROA
4h 53m
1 stop
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$269Delta
Sat, May 16 - Sat, May 23
Delta Logo
6:41 pm - 12:34 am
DSM
-
ROA
4h 53m
1 stop
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$279Delta
Fri, May 15 - Tue, May 19
Delta Logo
6:41 pm - 12:34 am
DSM
-
ROA
4h 53m
1 stop
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$334Delta
Sat, May 16 - Sat, May 23
Delta Logo
6:15 am - 2:39 pm
DSM
-
ROA
7h 24m
2 stops
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$339Delta
Fri, May 15 - Tue, May 19
Delta Logo
6:41 pm - 12:34 am
DSM
-
ROA
4h 53m
1 stop
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$344Delta
Wed, May 20 - Sun, May 24
American Airlines Logo
8:56 am - 5:33 pm
DSM
-
ROA
7h 37m
2 stops
American Airlines Logo
7:58 pm - 11:59 pm
ROA
-
DSM
5h 01m
1 stop
$357American Airlines
Sat, May 16 - Sat, May 23
Delta Logo
6:15 am - 2:39 pm
DSM
-
ROA
7h 24m
2 stops
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$369Delta
Wed, May 20 - Sun, May 24
United Airlines Logo
11:40 am - 11:44 pm
DSM
-
ROA
11h 04m
2 stops
United Airlines Logo
6:47 am - 10:21 am
ROA
-
DSM
4h 34m
1 stop
$374United Airlines
Sat, May 16 - Sat, May 23
Delta Logo
6:15 am - 2:39 pm
DSM
-
ROA
7h 24m
2 stops
Delta Logo
6:00 am - 11:03 am
ROA
-
DSM
6h 03m
1 stop
$379Delta
Wed, May 20 - Sun, May 24
United Airlines Logo
1:05 pm - 11:44 pm
DSM
-
ROA
9h 39m
2 stops
United Airlines Logo
6:15 am - 12:30 pm
ROA
-
DSM
7h 15m
2 stops
$401United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Roanoke flights

Get data-powered insights and trends into flights from Des Moines to Roanoke to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Roanoke?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Roanoke were found on Delta ($269) and American Airlines ($357).

Good to know

Low seasonJune
Cheapest flight$222
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from Des Moines to Roanoke

When to book flights from Des Moines to Roanoke

Are your dates flexible? Find out the best times to travel from Des Moines to Roanoke based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Roanoke

  • What is the cheapest flight from Des Moines to Roanoke?

    In the last 3 days, the lowest price for a flight from Des Moines to Roanoke was $222 for a one-way ticket and $269 for a round-trip.

  • Do I need a passport to fly between Des Moines and Roanoke?

    No, a passport isn't needed to fly from Des Moines to Roanoke. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Des Moines to Roanoke?

    Des Moines and Roanoke are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Roanoke.

  • Which aircraft models fly most regularly from Des Moines to Roanoke?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Roanoke?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Roanoke, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Roanoke, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Roanoke are Delta and American Airlines. With an average price for the route of $323 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $349 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Des Moines to Roanoke?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Roanoke.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Roanoke?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Roanoke from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Roanoke?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Roanoke with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and ROA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Roanoke?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Roanoke from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Roanoke

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Roanoke. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Roanoke? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8180 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

2.0 MediocreJaspreet, Feb 2026
SEA - SMF
Read more Delta reviews

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

This was one of the worst flights I’ve been on in years. I upgraded to comfort and had such an uncomfortable experience. The person next to me was oversized - which I understand - however, they took up their space and mine. I could only use about 50% of my seat space to not be physically touching this person the entire flight and there was no spatial awareness. I also could not use the seat outlet because their body was obstructing it. It was very inconvenient. Their body kept touching me repeatedly during the flight and I felt very uncomfortable. To pay more for an upgraded space and then not even being able to use it was highly disappointing.

No wheel chair as requested at Atlanta arrival on first flight.

Only freetext wifi was available in flight; browsing WiFi required payment. Since the seats had no in flight entertainment, Delta should revisit this policy on this longer flight.

Only water, tea or coffee served midflight, even to comfort seating. Man next to me needed two seats and took up a portion of my seat and Delta did nothing.

The flight was great as well as the airline staff

First class and monitors weren’t working for mine & my husbands. Eventually fixed, but quite annoyed as we bought first class. Also, No foot rests.

Prior to takeoff, the pilot told us there was a possibility of not being able to land and going to Portland. Well that happened, we took off and then did 8 loops around Spokane before the pilot told us we ran out of fuel and had to go to Portland. So for a 35 minute flight we have now been on the plane for 3 hours (boarded at 6:50 am and landed in Portland at 10:30). Then, we just sat in Portland's airport with no updates of when we can start heading back. All of a sudden, our pilots and crew just left, leaving us stranded in a different city and state. We continued to sit in Portland until we finally got a new crew assigned and boarded the plane (This was from 10:30-2). We then sat on the plane for an additional hour before take off because they had to count us multiple times. We finally landed in Spokane at 3:55 PM. So a flight that should have taken at max an hour took us 10 hours and we missed the majority of the recruiting event we went for.

It was delayed but other than that it was great.

Got on the plane and sat there for an hour before departure.

The flight was on time/early, attentive crew, and everything overall went smoothly. Disappointed that WIFI was not working for the flight.

One day, I do so hope for a gluten free snack! Seems like with the rest of the world FINALLY figuring out what gluten free is, American Airlines would too. Fingers crossed!!

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

Flight was on time and the meal and service were good.

Flight was delayed for 2 hours, then last minute the change to on time. The satélite location is far and a nightmare to get to.

This was a horrible experience. I’ve experienced several delays at this point and still not home. I was supposed to be home by 8:30 last night and here I sit at 7 am on a plane STILL unable to go home because of American Airlines.

Generally good. Flight left on time and the seats are comfortable. Plenty of space in front if you in you choose a comfort plus seat, completely worth spending the extra money given the amount of hours the flight lasts. The food tastes good but I would say it’s a the amount is too little. The crew was friendly and efficient. There was a some turbulence at different points into the flight. American Airlines has good deals to NZ if you book with plenty of time before you plan on going.

the plane was so hot!! the air-conditioning was barely blowing. The flight was delayed, and we had to sit on the hot plane before take off for an extended amount of time, waiting on international passengers. Would not have been so bad if it was not so hot. They said it would get better after take off, but it did not.

They are always late and seats was also not having working charger

We flew in first class. The crew did not offer drinks before the flight took off, but they treated us well during the flight. The food was excellent. There was actually too much food served, but it was nice to have all the options.

Everything you need to know for your flight from Des Moines to Roanoke

Information on your arrival and departure airports