DSM - ROA

$329 Find Cheap Flights from Des Moines to Roanoke

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Roanoke departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Roanoke

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Roanoke, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Roanoke, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$329
Typical prices: $418-$332
American Airlines
Fri 5/22Tue 6/2
DSM - ROA • 1 stop
Top airlines
Cheapest • from $329 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Roanoke. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $270 (round-trip)
Shortest trip • 4h 53m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Roanoke!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Roanoke (DSM-ROA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Roanoke that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Roanoke

Fri, May 22 - Tue, Jun 2
American Airlines Logo
1:37 pm - 10:20 pm
DSM
-
ROA
7h 43m
1 stop
American Airlines Logo
7:58 pm - 12:17 am
ROA
-
DSM
5h 19m
1 stop
$329American Airlines
Thu, Jul 2 - Sun, Jul 5
American Airlines Logo
1:41 pm - 10:18 pm
DSM
-
ROA
7h 37m
1 stop
American Airlines Logo
7:53 pm - 12:09 am
ROA
-
DSM
5h 16m
1 stop
$384American Airlines
Sat, Sep 19 - Tue, Sep 22
United Airlines Logo
5:00 am - 2:18 pm
DSM
-
ROA
8h 18m
2 stops
United Airlines Logo
6:47 am - 10:11 am
ROA
-
DSM
4h 24m
1 stop
$404United Airlines
Sat, Sep 19 - Tue, Sep 22
United Airlines Logo
5:00 am - 2:18 pm
DSM
-
ROA
8h 18m
2 stops
United Airlines Logo
10:30 am - 7:24 pm
ROA
-
DSM
9h 54m
2 stops
$409United Airlines
Sat, Sep 19 - Tue, Sep 22
United Airlines Logo
6:00 am - 1:35 pm
DSM
-
ROA
6h 35m
1 stop
United Airlines Logo
6:47 am - 10:11 am
ROA
-
DSM
4h 24m
1 stop
$454United Airlines
Sun, Jun 21 - Fri, Jun 26
Allegiant Air Logo
9:27 am - 3:18 pm
DSM
-
ROA
28h 51m
1 stop
Allegiant Air Logo
4:03 pm - 4:16 pm
ROA
-
DSM
25h 13m
1 stop
$473Allegiant Air
Thu, Jul 2 - Sun, Jul 5
United Airlines Logo
6:00 am - 1:55 pm
DSM
-
ROA
6h 55m
2 stops
United Airlines Logo
6:40 am - 10:27 am
ROA
-
DSM
4h 47m
1 stop
$484United Airlines
Fri, May 22 - Tue, Jun 2
American Airlines Logo
1:37 pm - 9:20 pm
DSM
-
ROA
6h 43m
1 stop
American Airlines Logo
8:55 am - 6:40 pm
ROA
-
DSM
10h 45m
2 stops
$511American Airlines
Sun, Jun 21 - Fri, Jun 26
Allegiant Air Logo
10:53 am - 3:18 pm
DSM
-
ROA
27h 25m
2 stops
Allegiant Air Logo
4:03 pm - 4:16 pm
ROA
-
DSM
25h 13m
1 stop
$563Allegiant Air
Fri, May 22 - Tue, Jun 2
United Airlines Logo
11:23 am - 11:44 pm
DSM
-
ROA
11h 21m
2 stops
United Airlines Logo
10:39 am - 10:40 pm
ROA
-
DSM
13h 01m
2 stops
$690United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Roanoke flights

Get data-powered insights and trends into flights from Des Moines to Roanoke to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Roanoke?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Roanoke departing in May.

What is the cheapest month to fly from Des Moines to Roanoke?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Roanoke, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Roanoke is March, where tickets cost $0 (return) on average. On the other hand, the most expensive months are February and July, where the average cost of round-trip tickets is $441 and $398 respectively.

Good to know

Cheapest flight$329
Most popular time to fly with an average 2% increase in price.
Flight from Des Moines to Roanoke

When to book flights from Des Moines to Roanoke

Are your dates flexible? Find out the best times to travel from Des Moines to Roanoke based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Roanoke

  • What is the cheapest flight from Des Moines to Roanoke?

    In the last 3 days, the lowest price for a flight from Des Moines to Roanoke was $329 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Roanoke?

    No, a passport isn't needed to fly from Des Moines to Roanoke. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Des Moines to Roanoke?

    Des Moines and Roanoke are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Roanoke.

  • Which aircraft models fly most regularly from Des Moines to Roanoke?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Roanoke?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Roanoke, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Roanoke, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Roanoke are Delta and American Airlines. With an average price for the route of $338 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $376 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Roanoke?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Roanoke.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Roanoke?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Roanoke from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Roanoke?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Roanoke with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and ROA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Roanoke?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Roanoke from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Roanoke

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Roanoke. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Roanoke? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8451 reviews
8.1Boarding
7.2Food
7.8Comfort
7.8Entertainment
8.5Crew
Airline reviews

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

6.0 GoodAnonymous, May 2026
PDX - MSP
Read more Delta reviews

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

The small flights with Valet Luggage has a poor service

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Everything you need to know for your flight from Des Moines to Roanoke

Information on your arrival and departure airports