SAN

$149 Find Cheap Flights from Florida Keys to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Florida Keys to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to San Diego

Thu, May 14 - Sun, May 17
Frontier Logo
5:45 pm - 12:11 am
MIA
-
SAN
9h 26m
1 stop
Frontier Logo
9:07 pm - 7:32 am
SAN
-
MIA
7h 25m
1 stop
$290Frontier
Thu, May 14 - Sun, May 17
Frontier Logo
5:45 pm - 12:11 am
MIA
-
SAN
9h 26m
1 stop
Frontier Logo
9:07 pm - 7:32 am
SAN
-
MIA
7h 25m
1 stop
$310Frontier
Sun, Apr 5 - Sun, Apr 5
Frontier Logo
5:50 am - 8:26 pm
MIA
-
SAN
17h 36m
1 stop
Frontier Logo
9:28 pm - 5:49 am
SAN
-
MIA
29h 21m
1 stop
$314Frontier
Thu, Apr 2 - Tue, Apr 7
Frontier Logo
10:39 am - 10:58 pm
MIA
-
SAN
15h 19m
1 stop
Frontier Logo
6:25 am - 5:49 am
SAN
-
MIA
20h 24m
1 stop
$317Frontier
Sun, Mar 29 - Wed, Apr 1
Frontier Logo
5:50 am - 8:05 am
MIA
-
SAN
29h 15m
1 stop
Frontier Logo
6:25 am - 9:44 am
SAN
-
MIA
24h 19m
2 stops
$326Frontier
Sat, Jun 6 - Sat, Jun 13
Frontier Logo
9:32 pm - 6:37 pm
MIA
-
SAN
24h 05m
1 stop
Frontier Logo
6:25 am - 5:48 am
SAN
-
MIA
20h 23m
1 stop
$330Frontier
Thu, Mar 19 - Tue, Mar 31
Multiple Airlines Logo
9:14 am - 8:05 am
MIA
-
SAN
25h 51m
2 stops
Multiple Airlines Logo
8:25 am - 5:38 am
SAN
-
MIA
18h 13m
1 stop
$336Multiple Airlines
Fri, Apr 17 - Sat, Apr 18
United Airlines Logo
4:38 pm - 9:26 pm
EYW
-
SAN
7h 48m
1 stop
United Airlines Logo
10:20 pm - 1:31 pm
SAN
-
EYW
12h 11m
1 stop
$499United Airlines
Fri, Apr 17 - Sat, Apr 18
United Airlines Logo
4:38 pm - 9:26 pm
EYW
-
SAN
7h 48m
1 stop
United Airlines Logo
11:00 am - 3:57 pm
SAN
-
EYW
25h 57m
2 stops
$524United Airlines
Fri, Apr 17 - Sat, Apr 18
United Airlines Logo
4:38 pm - 9:26 pm
EYW
-
SAN
7h 48m
1 stop
United Airlines Logo
11:00 am - 3:57 pm
SAN
-
EYW
25h 57m
2 stops
$534United Airlines
Useful Info

Good to know

Low seasonJanuary
Cheapest flight$165
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Miami to San Diego

FAQs for booking flights from Florida Keys to San Diego

  • How does KAYAK find such low prices on flights from Florida Keys to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Florida Keys to San Diego

 
Need help choosing which airline to fly with from Florida Keys to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 12042 reviews
8.1Boarding
8.5Crew
7.8Comfort
7.1Food
7.0Entertainment
Airline reviews

The boarding process could be clearer, there's never a call for group f

8.0 ExcellentCarlos, Feb 2026
JFK - SAN
Read more Alaska Airlines reviews

The boarding process could be clearer, there's never a call for group f

good, no complaints but nothing to rave about. It was fine

I love Alaska! We arrived on the later side without seat assignments only to find the had oversold the flight by 1. The attendants worked extra hard to find a way for our party of 7 to stay together and we made it on the flight! Loved the free WiFi also!

The he whole flight was very smooth on every aspects.

Flight cancelled and deplaned. Rescheduled 8 hours later at a different airport. Ended up at destination but late.

Due to plane delays on both legs of my flight home, I had to be rerouted from Santa Rosa to Las Vegas on Skywest and then to DCA on American. SkyWest airlines sat on runway in Las Vegas for 20 minutes waiting for gate to clear. My boarding pass for American that I was given by Alaska was incomplete and the Las Vegas airport lacked signage and departure boards. I barely made my flight bc it was so confusing. American Airlines has a much better wireless connection. I’ll never fly Alaska again. It clearly has problems.

We left about 30 minutes late due to ramp issues. It did not impact me, but I know others on the flight had very tight connections to Maui.

The crew was very friendly. Boarding was quick and efficient.

No WiFi. Terrible food. Very long walk to the gate and from the gate after landing. Gate changed without notice.

I enjoyed the Starlink access but didn't have much time to use it. It also kept dropping me so I gave up. The food was very good though when I asked for a different "dessert" they didn't have anything. Chocolate Brownie Cookies are not suitable for everyone...maybe children. The flight staff were amazing - at least in First Class! My first time ever! The trip from Boise to San Diego was FAR better than going to Boise.

Left a few minutes early. Got in 15 minutes early. Very attentive service on board. Very organized boarding.

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

Overall we had a good experience during our flight from San Francisco to Houston.

it was a very short flight so my expectations were low.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

did not have enough meal for first class passengers so offer us snack

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Our flight was canceled. I will never use Kayak nor Frontier for travel again. The entire experience was a headache.

It didn’t happen. I booked it and then was told it wasn’t available and then forced to pay far higher prices for a worse option

This company socks. It's fraud. They canceled our flight yesterday, and today we were late because of a really long line at the check in bag. At the rebook station, there was ton of people. The workers were all rude. I am gonna make a report to FTC.

Flight got delayed for 5 hours no good explanation was offered ;(

There was no one at the counter to assist with our check in. The app didn’t work, so I arrived at the airport with time to check in and I couldn’t because no employees were there. When I finally got someone on the phone, it was inside the 60min rule and they said I could no longer check in and they could sell me another ticket. We had to scramble and pay an additional $800 for tickets and THEN AFTER (about 60 min from my original convo with customer service and 10min after original departure time) I had boarded my new flight, there was email saying my original flight from Frontier was delayed and leaving 2hr 50min later, but I STILL wouldn’t have been able to check in. Which means customer service should have been able to see it and let me check in because I was well within my check in time. When I call Frontier, they hang up on me. So their app didn’t work and they employees left and they take zero responsibility or assistance with their “customer service”

Terrible. The canceled my entire flight when I requested a refund for a trip frontier canceled trip one way.

i was unable to check in the flight. refund requested

Everyone seemed to be in zone 1 for boarding. Maybe break it up a little. Otherwise, smooth flight.

I think Frontier was very good at communication. Their app worked very well. Loading was great and the flight was nice and easy.

The experience was good. No frills but I got there safe and sound and on time.

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