SAN

$47 Find Cheap Flights from Florida Keys to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flight Deals from Florida Keys to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Florida Keys to San Diego

KAYAK's recommended round-trip deals from the most popular airlines that fly from Florida Keys to San Diego.
Discover the best prices for you by selecting your travel dates on KAYAK.
Spirit Airlines Logo
8:55 pm - 7:13 amMIA-SAN
13h 18m1 stop
Spirit Airlines Logo
6:15 am - 5:43 amSAN-MIA
20h 28m1 stop
$124Spirit Airlines
Find Deal
Wed, May 28 - Wed, Jun 4
Spirit Airlines Logo
8:55 pm - 7:13 amMIA-SAN
13h 18m1 stop
Spirit Airlines Logo
6:58 pm - 5:43 amSAN-MIA
7h 45m1 stop
$140Spirit Airlines
Find Deal
Wed, May 14 - Fri, May 16
Frontier Logo
6:00 am - 5:10 pmMIA-SAN
14h 10m1 stop
Frontier Logo
1:23 pm - 5:22 amSAN-MIA
12h 59m1 stop
$178Frontier
Find Deal
Sat, May 10 - Tue, May 13
Frontier Logo
7:10 am - 11:56 amMIA-SAN
7h 46m1 stop
Frontier Logo
7:16 pm - 6:00 amSAN-MIA
7h 44m1 stop
$196Frontier
Find Deal
Fri, May 30 - Fri, Jun 6
American Airlines Logo
8:15 pm - 10:37 pmMIA-SAN
5h 22mnonstop
American Airlines Logo
10:13 pm - 6:18 amSAN-MIA
5h 05mnonstop
$237American Airlines
Find Deal
Fri, May 30 - Mon, Jun 9
American Airlines Logo
8:15 pm - 10:37 pmMIA-SAN
5h 22mnonstop
American Airlines Logo
10:25 pm - 6:12 amSAN-MIA
4h 47mnonstop
$238American Airlines
Find Deal
Fri, May 30 - Mon, Jun 2
Delta Logo
7:00 am - 12:25 pmMIA-SAN
8h 25m1 stop
Delta Logo
9:40 pm - 10:57 amSAN-MIA
10h 17m1 stop
$257Delta
Find Deal
Fri, Jun 13 - Mon, Jun 16
Delta Logo
6:25 pm - 11:42 pmEYW-SAN
8h 17m1 stop
Delta Logo
6:15 am - 5:30 pmSAN-EYW
8h 15m1 stop
$283Delta
Find Deal
Thu, May 29 - Tue, Jun 3
Alaska Airlines Logo
6:21 pm - 9:32 amMIA-SAN
18h 11m2 stops
Alaska Airlines Logo
5:18 pm - 5:21 pmSAN-MIA
21h 03m2 stops
$349Alaska Airlines
Find Deal
Tue, May 20 - Sat, May 24
Alaska Airlines Logo
6:21 pm - 5:14 pmMIA-SAN
25h 53m2 stops
Alaska Airlines Logo
3:45 pm - 5:21 pmSAN-MIA
22h 36m1 stop
$354Alaska Airlines
Find Deal
Tue, May 20 - Sat, May 24
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Good to know

Low seasonJanuary
High seasonJuly
Cheapest flight$47
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Miami to San Diego

FAQs for booking flights from Florida Keys to San Diego

  • How does KAYAK find such low prices on flights from Florida Keys to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top 5 airlines serving from Florida Keys to San Diego

Need help choosing which airline to fly with from Florida Keys to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 9968 reviews
7.9Comfort
7.1Food
8.5Crew
7.1Entertainment
8.2Boarding
Airline reviews

The flight was canceled and very little help given at the check in desk. Everyone at the desk says: just go on the app and see how they rebooked you. I mean come on it’s embarrassing customer service.

2.0 MediocreAnonymous, Mar 2025JAC - SAN
Read more Alaska Airlines reviews

The flight was canceled and very little help given at the check in desk. Everyone at the desk says: just go on the app and see how they rebooked you. I mean come on it’s embarrassing customer service.

The registration was chaotic. The kiosks didn't work for most people, and most had to do registration and receive boarding slips with a person. It took about an hour to get through he process, and I was worrying that I will be late to the flight. However, the personnel was great - courteous, professional, and was able to work through the problems.

I upgraded my seat and the service and boarding were wonderful. My flight attendant was very helpful when I experienced nausea on the flight (a first time experience). Flight arrived early which was nice. The only negative was many airlines have screens to provide some on flight entertainment, this aircraft did not. I had planned to read and listen to an audiobook on my flights, so no big deal on my part. The USB plug ins were broken on both my seat and the center seat, so I was not able to charge my phone during the flight, I will add 2 of the three USBs were broken on ride from San Diego as well. I would attribute this to the design, it is a very awkward angle to plug in, so frequent and perhaps not so gentle attempts to plug in have caused them to break.

Stay with what you are doing. Excellent service and ahead of schedule. Well done.

We had to cancel and we’re treated fairly with 100%refund quickly

There was an issue with water that led to us not having potable water onboard. They dumped the onboard water and we were two hours late taking off.

All good. Great food and entertainment when there isn’t any on a one hour flight

The flight from San Diego to San Jose gate 28A The two persons working there didn’t even turn on the display board. The display board saying to Sacramento. When I asked she was rude and showed the board . Then he realized And changed. Every one was confused because we are running late to catch that flight coming from IAD. Very irresponsible staff.

Great crew, great boarding, old B-list movies, no free meal service, child kicking my seat back all flight long, early arrival, then 40 minute, confused wait for bags.

I liked the flight attendant named Tyler. He was charismatic and genuine. I like the pilot in my second flight, he was considerate to everyone’s feelings. I liked the people I sat beside. I like the plane size. I like Alaska airlines

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Seats are much much more comfortable than United, which is what I usually fly

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

They separated our seats and moved us to the back of the plane. Hundreds of dollars and thousands of miles used and this was my platinum member experience.

AC barely worked on a 50 minute flight. It was very warm the whole flight. Flight was very bumpy and hard landing.

Got on the plane and then needed to deboard the plane because they didn’t have any pilots?

The flight was canceled two hours before departure, it took over five hours to rebook us on another flight.

Rough day of travel all the way around. Wrong info given to us multiple times and mistakes in their booking making our trip 10 hours longer than planned. I’m bummed because I fly Delta all the time and love them. Mistakes happen. Just bummed that this was a rare trip our whole family was traveling together.

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Plane was pretty clean, staff was friendly and helpful, flight left about on time arrived early. Took a long time to board and get off the plane - carry on items didn't have enough room so people had to move all around to find places.

The service and food needs to improve to catch up with other international flights

Would have been good to have a meal since it was a 5.5 hour flight

We boarded after several delays due to mechanical failure and a gate change. The seat cushion in the exit row was very compressed and offered no cushion, making the four-hour journey reasonably uncomfortable. The WiFi worked for a few people, but for most, it did not, and you cannot get entertainment unless you can connect—American Airlines flights do not have seatback screens, and you must use your mobile phone.

AA is always pretty solid. Was on time all the way around today so can’t complain!

Worst airline ever! The guy weighing my bag had his foot on the metal plate and when I called him out on it, I got this stupid little smirk. La is a scam and so is Spirit Airlines. All the flight attendants looked like they hated our flight just as much as we did.

Unclear pricing; ended up being charged an extra $52 just to get onboard

Spirit is awful. Too expensive for what you get. Stop nickel and diming.

would be great to get basic water, soda at least and stop charging for carry ons

Your crew is a representation of your Standards and Values. The crew from Seattle to LAX, was very disappointing. The crew was more interested in hanging out at the lobby area. Talking, laughing loudly and eating all the snacks. They did not do regular rounds to see if customers needed anything. This was a huge disappointment. I will no longer be flying with your airlines moving forward.

- flight attendants not very friendly. - Paid for WiFi and plane didn’t have it working , never got a refund.

We got to fly on the new airplane. Much better as it’s roomier and cleaner than before. Most Importantly it’s much more comfortable. I still can’t move the seat back but the extra space made up for it. I didn’t taste the food or drinks because they charge for everything so I didn’t bother. I didn’t experience the entertainment because I downloaded my own movies on my phone. The crew was great. The flight itself was smooth . No complaints.

I was comfortable because I upgraded. I would not have been comfortable in economy. It was a short flight so there was limited food service and no inflight entertainment.

I thought since I upgraded my seat I would get some perks. Free water, free snacks. Free carry on luggage.

It’s ridiculous to pay for carry-on luggage. I also wasn’t given an option to specify I have carry on bag at time of ticket purchase. I also could not specify I have carry on luggage at time of online check-in.

The seats were hard molded plastic covered in plastic vinyl. And the scam to charge people extra to sit together. Don’t they know we can just ask someone to trade seats. And watching the staff separate young children from parents… super classy. We had to guilt them into offering up our seats. This companies policies suck. Don’t give them your money.

Seats are uncomfortable but price is good. Guess I can put up with misery for four hours.

Cancelled and declined to find alternatives Earlier flight is 2 days later Sent the cancellation notification very late, wish I knew earlier would have stayed to watch the Miami open final game Very disappointing service

They switched my flight to Spirit, Never using Kayak again,

The flight itself was ok and the pilot was very communicative. However, our flight was delayed for almost 3 hours, the gate was changed 3 times and there was no communication as we were waiting. The flight staff was overall a little crabby...I understand as they probably had a long day but we all did.

Asked for a seat change to be w my wife at the gate they were great in sorting it out to make it happen

Everything went as planned. Crew was great. Seats were still not that comfortable.

They cancelled the flight and did nothing. I should be compensated for my uber rides to and from airport. Not a good service by frontier or kayak.

No frills for sure. No gate announcements about flight delay, not even water to drink on the flight.

The worst service , the agents from the counter are really bad . Poor customer service . They didnt help me to get in the flight . I was on line when they close the flight without telling and I couldn’t board the plane . I will like to get my money back ey back because it was their fault. Really bad management , bad manners, bad additud

Everything you need to know for your flight to San Diego

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