SAN

$139 Find Cheap Flights from Florida Keys to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$218
Overall average: $376
Frontier
Sa 2/14Sa 2/21
MIA - SAN • 1 stop
Cheapest non-stop
$339
Typical prices: $321-$458
American Airlines
Mi 3/25Mi 4/8
MIA - SAN • Non-stop
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Flight Deals
Useful Info
Flight Deals

Cheap Flights from Florida Keys to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Florida Keys to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Florida Keys to San Diego

Sa, Feb 14 - Sa, Feb 21
Frontier Logo
6:25 am - 12:08 am
MIA
-
SAN
20h 43m
1 stop
Frontier Logo
6:25 am - 5:14 am
SAN
-
MIA
19h 49m
1 stop
$218Frontier
Mi, Mrz 4 - So, Mrz 8
Frontier Logo
6:25 am - 9:41 pm
MIA
-
SAN
18h 16m
1 stop
Frontier Logo
6:33 pm - 7:52 pm
SAN
-
MIA
22h 19m
2 stops
$222Frontier
Do, Feb 12 - So, Feb 15
Frontier Logo
9:10 pm - 8:50 am
MIA
-
SAN
14h 40m
1 stop
Frontier Logo
6:25 am - 5:14 am
SAN
-
MIA
19h 49m
1 stop
$223Frontier
Mi, Feb 18 - Sa, Feb 21
Frontier Logo
7:09 pm - 11:14 am
MIA
-
SAN
19h 05m
2 stops
Frontier Logo
12:23 pm - 5:14 am
SAN
-
MIA
13h 51m
1 stop
$225Frontier
Do, Feb 19 - Mi, Feb 25
American Airlines Logo
3:51 pm - 10:40 pm
EYW
-
SAN
9h 49m
1 stop
American Airlines Logo
6:20 am - 6:19 pm
SAN
-
EYW
8h 59m
1 stop
$285American Airlines
Do, Feb 19 - Mi, Feb 25
American Airlines Logo
2:06 pm - 9:07 pm
EYW
-
SAN
10h 01m
1 stop
American Airlines Logo
9:44 am - 10:22 pm
SAN
-
EYW
9h 38m
2 stops
$290American Airlines
Do, Feb 19 - Mi, Feb 25
American Airlines Logo
3:51 pm - 9:39 pm
EYW
-
SAN
8h 48m
2 stops
American Airlines Logo
9:44 am - 10:22 pm
SAN
-
EYW
9h 38m
2 stops
$296American Airlines
Mi, Feb 18 - Mi, Feb 25
American Airlines Logo
3:20 pm - 8:56 pm
EYW
-
SAN
8h 36m
1 stop
American Airlines Logo
6:20 am - 6:19 pm
SAN
-
EYW
8h 59m
1 stop
$312American Airlines
Mi, Mrz 25 - Mo, Mrz 30
Delta Logo
7:30 am - 10:55 pm
EYW
-
SAN
18h 25m
2 stops
Delta Logo
10:30 pm - 10:48 am
SAN
-
EYW
9h 18m
1 stop
$386Delta
Di, Mrz 24 - Mo, Mrz 30
Delta Logo
2:40 pm - 8:36 pm
EYW
-
SAN
8h 56m
1 stop
Delta Logo
9:55 pm - 10:48 am
SAN
-
EYW
9h 53m
1 stop
$412Delta
Useful Info

Good to know

Low seasonSeptember
Cheapest flight$139
Best time to beat the crowds with an average 10% drop in price.
Flight from Miami to San Diego

FAQs for booking flights from Florida Keys to San Diego

  • How does KAYAK find such low prices on flights from Florida Keys to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Florida Keys to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Florida Keys to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Florida Keys to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Florida Keys with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Florida Keys to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Florida Keys to San Diego

 
Need help choosing which airline to fly with from Florida Keys to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 11740 reviews
7.0Entertainment
8.5Crew
7.1Food
7.8Comfort
8.1Boarding
Airline reviews

No WiFi. Terrible food. Very long walk to the gate and from the gate after landing. Gate changed without notice.

2.0 MediocreJerry, Jan 2026
ORD - SAN
Read more Alaska Airlines reviews

No WiFi. Terrible food. Very long walk to the gate and from the gate after landing. Gate changed without notice.

I enjoyed the Starlink access but didn't have much time to use it. It also kept dropping me so I gave up. The food was very good though when I asked for a different "dessert" they didn't have anything. Chocolate Brownie Cookies are not suitable for everyone...maybe children. The flight staff were amazing - at least in First Class! My first time ever! The trip from Boise to San Diego was FAR better than going to Boise.

One of the flight attendants treated my grandma who is 77 years old badly and would respond sarcastically. Example my grandma "do you have and honey by any chance" the flight attendant "does this look like a restaurant to you. She was also very rude to myself and my children giving us attitude and being sarcastic when answering.

we waited for 50 minutes to check a bag and missed a flight. do better.

The flight crew was very professional and pleasant. Our flight was delayed 3 hours, but Kayak informed me in advance

I really hate the seat assignment at the gate. I understand it is so families can sit together but it caused me and others a lot of unnecessary stress and confusion, enough for me to not fly Alaska again. The app is so awful that it did not even update my seat assignment on the boarding pass but sent me a notification of my seat... it showed in Apple Wallet but not in the Alaska app itself. That only made the stress worse. I think most people like myself prefer to know where they are seated at check in 24 hours before so they don't have to anxiously hang out at the gate the entire time. This is not a good use of your agents time either to be dealing with all of us asking where we are sitting. You should automatically assign the multiple seat purchases to be together before they check in and fill us solo travelers in those gaps as we check in.

Alaska Airlines have beautiful new airplanes that have comfortable seats but tight for a tall person like myself. They do provide upgrades to flyers but at a $140 cost. My flight went smooth and prompt as well as without a hitch. The flight crew were warm and friendly as well as very attentive. I'd recommend this airline over Frontier airlines any day.

Did not like that every price option offered, even the more expensive one, required I pay for my seat. My seat was changed without my consent My TSA did not show in Boarding Pass

Boarding passes could not be received online, even after online check-in. While they appeared on the Alaska.com app, they did not transfer to inbox or messages and were not available at all on the Alaska.com app following the check-in process. There was no choice other than to get boarding passes at the airport counter.

Poor, the last leg of our trip was cancelled and we didn't know about it until we arrived at the airport. Another flight on the same airline was not available until three days later which would have ruined our vacation. Luckily we were able to get re-blooked on another airline after spending hours at the airport.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

Food was surprisingly good but the WiFi was not great

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Flight was late - I was downgraded from first class to coach

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Plane boarded early a quickly, was mostly full. We left close to on time. And landed early.

7 hours delayed due to operational issues on United’s end. Basically laziness.

Flight was timely, relatively comfortable, with decent entertainment and food served. Only problem encountered was with the free messaging which I highly appreciate, but it did not work from iphone to non-iphones.

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

We are too tired and frustrated to comment politely at this point

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

It didn’t happen. I booked it and then was told it wasn’t available and then forced to pay far higher prices for a worse option

This company socks. It's fraud. They canceled our flight yesterday, and today we were late because of a really long line at the check in bag. At the rebook station, there was ton of people. The workers were all rude. I am gonna make a report to FTC.

Flight got delayed for 5 hours no good explanation was offered ;(

There was no one at the counter to assist with our check in. The app didn’t work, so I arrived at the airport with time to check in and I couldn’t because no employees were there. When I finally got someone on the phone, it was inside the 60min rule and they said I could no longer check in and they could sell me another ticket. We had to scramble and pay an additional $800 for tickets and THEN AFTER (about 60 min from my original convo with customer service and 10min after original departure time) I had boarded my new flight, there was email saying my original flight from Frontier was delayed and leaving 2hr 50min later, but I STILL wouldn’t have been able to check in. Which means customer service should have been able to see it and let me check in because I was well within my check in time. When I call Frontier, they hang up on me. So their app didn’t work and they employees left and they take zero responsibility or assistance with their “customer service”

Terrible. The canceled my entire flight when I requested a refund for a trip frontier canceled trip one way.

i was unable to check in the flight. refund requested

Everyone seemed to be in zone 1 for boarding. Maybe break it up a little. Otherwise, smooth flight.

I think Frontier was very good at communication. Their app worked very well. Loading was great and the flight was nice and easy.

The experience was good. No frills but I got there safe and sound and on time.

Great for the price. No wifi or entertainment, but gate agents and crew were fantastic and we boarded quickly and left on time.

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