$132 Find Cheap Flights from Fort Myers to St. Louis - Compare and Save

Among airlines operating Fort Myers to St. Louis flights:

• Southwest: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Only Southwest operates flights between Fort Myers and St. Louis.

Flights from Fort Myers to St. Louis usually depart from Fort Myers SW Florida Intl (RSW) and arrive at Lambert-St Louis (STL).

Here are some options for this route, based on selected ticket types and cabin classes:

• Southwest: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

Only Economy Class is available on flights from Fort Myers to St. Louis.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $359 round-trip via Nashville Intl (BNA), compared to $457 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$90 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737 MAX 8 family is used most often on this route, operated mainly by Southwest and United Airlines. Other aircraft seen on the route include Boeing 737-800 Passenger/BBJ2 (winglets) variants.

One-stop flights from Fort Myers to St. Louis most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 58% of one-stop connections
• Charlotte Douglas (CLT) - 22% of one-stop connections
• Chicago O'Hare Intl (ORD) - 14% of one-stop connections
• Nashville Intl (BNA) - 4% of one-stop connections

Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 26% on the Fort Myers to St. Louis route. Wednesday is the cheapest departure day at $401 round-trip on average, while Monday is the most expensive at $539, a difference of $138. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Morning is the busiest departure period on Fort Myers to St. Louis flights, with 50% of flights leaving in that window. Evening departures account for 50%, afternoon flights for 0%, and night flights for 0%.

Some of the most popular sights in St. Louis are Downtown St. Louis, Busch Stadium and Enterprise Center. These are among the most viewed places in St. Louis on KAYAK.

These are the earliest and latest flight times available from Fort Myers to St. Louis:

• Earliest: departs at 5:25 am and lands at 8:03 am
• Latest: departs at 9:20 pm and lands at 11:58 pm.

The flight takes about 2h 38m.

Last-minute fares on this route - booked within 2 weeks of departure - run 37% above the route average of $439. Book 5 weeks before departure for the lowest fares.

A nonstop flight from Fort Myers to St. Louis takes 2h 38m, covering 980 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $328 to $1,948. That means the highest observed fare was about 6x higher than the lowest one.

One-way fares from Fort Myers to St. Louis are currently lower than usual. Average one-way flight prices are about $151, which is 35% below the typical average for this route.

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 4h 35m, compared with 4h 38m via Atlanta Hartsfield-Jackson (ATL) and 5h 00m via Charlotte Douglas (CLT).

St. Louis is 1 hour behind Fort Myers (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
• Hertz
• Budget
• Alamo
• Enterprise Rent-A-Car
• Payless

Round-trip flights from Fort Myers to St. Louis range from $366 to $530, with an average of $439 over the past 12 months. Anything below $366 counts as a good deal.