GNV - DSM

$481 Find Cheap Flights from Gainesville to Des Moines

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Gainesville to Des Moines departing on 2/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Gainesville to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Gainesville to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$481
Delta
Fri 2/13Tue 2/17
GNV - DSM • 1 stop
Cheapest one-way
Multiple Airlines
Fri 1/30
GNV - DSM • multi-stop
Top airlines
Delta
Cheapest • from $481 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Gainesville to Des Moines (GNV-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Gainesville to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Gainesville to Des Moines

Fri, Feb 13 - Tue, Feb 17
Delta Logo
6:00 am - 11:01 am
GNV
-
DSM
6h 01m
1 stop
Delta Logo
5:15 pm - 10:34 pm
DSM
-
GNV
4h 19m
1 stop
$481Delta
Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
3:08 pm - 9:59 pm
GNV
-
DSM
7h 51m
1 stop
American Airlines Logo
11:17 am - 11:59 pm
DSM
-
GNV
11h 42m
2 stops
$486American Airlines
Fri, Feb 13 - Tue, Feb 17
American Airlines Logo
3:08 pm - 11:40 pm
GNV
-
DSM
9h 32m
2 stops
American Airlines Logo
11:17 am - 11:59 pm
DSM
-
GNV
11h 42m
2 stops
$491American Airlines
Tue, Feb 17 - Sun, Feb 22
American Airlines Logo
4:15 pm - 11:48 pm
GNV
-
DSM
8h 33m
1 stop
American Airlines Logo
5:00 am - 2:43 pm
DSM
-
GNV
8h 43m
2 stops
$495American Airlines
Tue, Feb 17 - Sun, Feb 22
American Airlines Logo
6:00 am - 1:04 pm
GNV
-
DSM
8h 04m
2 stops
American Airlines Logo
5:00 am - 2:43 pm
DSM
-
GNV
8h 43m
2 stops
$526American Airlines
Tue, Feb 17 - Sun, Feb 22
American Airlines Logo
4:15 pm - 11:48 pm
GNV
-
DSM
8h 33m
1 stop
American Airlines Logo
3:26 pm - 11:00 pm
DSM
-
GNV
6h 34m
1 stop
$610American Airlines
Booking Insights

KAYAK's insights & trends for Gainesville to Des Moines flights

Get data-powered insights and trends into flights from Gainesville to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Gainesville to Des Moines?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Gainesville to Des Moines were found on Delta ($481) and American Airlines ($486).

Find deals

Good to know

Cheapest flight$481
Flight from Gainesville to Des Moines

When to book flights from Gainesville to Des Moines

Are your dates flexible? Find out the best times to travel from Gainesville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Gainesville to Des Moines

  • What is the cheapest flight from Gainesville to Des Moines?

    In the last 3 days, the lowest price for a flight from Gainesville to Des Moines was $481 for a round-trip ticket.

  • Do I need a passport to fly between Gainesville and Des Moines?

    A passport is not required to fly from Gainesville to Des Moines.

  • Which airports will I be using when flying from Gainesville to Des Moines?

    Gainesville and Des Moines are both served by 1 main airport. You will leave Gainesville from Gainesville Regional and will be arriving at Des Moines.

  • Which aircraft models fly most regularly from Gainesville to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Gainesville to Des Moines?

    oneworld is the only airline alliance operating flights between Gainesville and Des Moines.

  • How does KAYAK find such low prices on flights from Gainesville to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Gainesville to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Gainesville to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Gainesville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Gainesville to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Gainesville with another airline. Booking your flights between Gainesville and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Gainesville to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Gainesville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Gainesville to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Gainesville to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Gainesville to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11207 reviews
6.9Entertainment
7.2Comfort
8.0Crew
7.5Boarding
6.4Food
Airline reviews

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

10.0 ExcellentCindy, Jan 2026
MIA - BHM
Read more American Airlines reviews

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Little warm on the plane and delayed for an hour

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

Boarding was organized and timely. Food was mediocre, especially for first class travel.

We were 4+ hours delayed. AA is absolutely obnoxious. They just kept pushing back the time to the point where we did not get into Vegas until after midnight when we were supposed to arrive like 845pm.

My last flight on 25 Dec, it’s Christmas Day, everyone happy and very good mood. I really enjoy traveling with Americans Airlines from Miami to Minneapolis my home town after long flight from lhe to Doha then Miami. Thank you again to make my travels comfortable and relaxed. Best regards

Everything you need to know for your flight from Gainesville to Des Moines

Information on your arrival and departure airports

Gainesville (GNV)
Des Moines (DSM)