GNV - DSM

$475 Find Cheap Flights from Gainesville to Des Moines

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Gainesville to Des Moines departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Gainesville to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Gainesville to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$475
American Airlines
Sat 3/28Wed 4/1
GNV - DSM • 1 stop
Top airlines
American Airlines
Cheapest • from $475 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Gainesville and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $394 (round-trip)
Atlanta (ATL)
Shortest trip • 5h 15m (one-way)
Insights
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We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Gainesville to Des Moines (GNV-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Gainesville to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Gainesville to Des Moines

Sat, Mar 28 - Wed, Apr 1
American Airlines Logo
4:15 pm - 11:46 pm
GNV
-
DSM
8h 31m
1 stop
American Airlines Logo
1:52 pm - 10:27 pm
DSM
-
GNV
7h 35m
1 stop
$475American Airlines
Sat, Mar 28 - Wed, Apr 1
American Airlines Logo
5:45 pm - 9:59 pm
GNV
-
DSM
5h 14m
1 stop
American Airlines Logo
6:40 am - 5:18 pm
DSM
-
GNV
9h 38m
2 stops
$480American Airlines
Sat, Apr 4 - Sun, Apr 5
American Airlines Logo
5:45 pm - 9:59 pm
GNV
-
DSM
5h 14m
1 stop
American Airlines Logo
7:00 am - 2:43 pm
DSM
-
GNV
6h 43m
1 stop
$481American Airlines
Sat, Apr 4 - Mon, Apr 6
American Airlines Logo
7:17 am - 2:56 pm
GNV
-
DSM
8h 39m
1 stop
American Airlines Logo
5:00 am - 2:43 pm
DSM
-
GNV
8h 43m
2 stops
$486American Airlines
Tue, Apr 7 - Sat, Apr 11
Delta Logo
7:00 pm - 10:38 pm
GNV
-
DSM
4h 38m
1 stop
Delta Logo
5:35 am - 12:47 pm
DSM
-
GNV
6h 12m
1 stop
$495Delta
Tue, Apr 7 - Sat, Apr 11
Delta Logo
7:00 pm - 10:38 pm
GNV
-
DSM
4h 38m
1 stop
Delta Logo
12:29 pm - 10:37 pm
DSM
-
GNV
9h 08m
2 stops
$506Delta
Fri, Apr 3 - Wed, Apr 8
Delta Logo
4:59 pm - 10:38 pm
GNV
-
DSM
6h 39m
1 stop
Delta Logo
11:33 am - 6:15 pm
DSM
-
GNV
5h 42m
1 stop
$541Delta
Fri, Apr 3 - Wed, Apr 8
Delta Logo
7:00 pm - 10:38 pm
GNV
-
DSM
4h 38m
1 stop
Delta Logo
10:28 am - 10:37 pm
DSM
-
GNV
11h 09m
2 stops
$546Delta
Sat, Apr 4 - Thu, Apr 9
Delta Logo
5:34 pm - 10:38 pm
GNV
-
DSM
6h 04m
1 stop
Delta Logo
5:20 pm - 10:37 pm
DSM
-
GNV
4h 17m
1 stop
$547Delta
Sat, Mar 28 - Wed, Apr 1
American Airlines Logo
6:00 am - 2:56 pm
GNV
-
DSM
9h 56m
2 stops
American Airlines Logo
1:37 pm - 10:27 pm
DSM
-
GNV
7h 50m
2 stops
$558American Airlines
Booking Insights

KAYAK's insights & trends for Gainesville to Des Moines flights

Get data-powered insights and trends into flights from Gainesville to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Gainesville to Des Moines?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Gainesville to Des Moines were found on American Airlines ($475) and Delta ($495).

Find deals

Good to know

Cheapest flight$475
Flight from Gainesville to Des Moines

When to book flights from Gainesville to Des Moines

Are your dates flexible? Find out the best times to travel from Gainesville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Gainesville to Des Moines

  • What is the cheapest flight from Gainesville to Des Moines?

    In the last 3 days, the lowest price for a flight from Gainesville to Des Moines was $475 for a round-trip ticket.

  • Do I need a passport to fly between Gainesville and Des Moines?

    A passport is not required to fly from Gainesville to Des Moines.

  • Which airports will I be using when flying from Gainesville to Des Moines?

    Gainesville and Des Moines are both served by 1 main airport. You will leave Gainesville from Gainesville Regional and will be arriving at Des Moines.

  • Which aircraft models fly most regularly from Gainesville to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Gainesville to Des Moines?

    oneworld is the only airline alliance operating flights between Gainesville and Des Moines.

  • How does KAYAK find such low prices on flights from Gainesville to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Gainesville to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Gainesville to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Gainesville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Gainesville to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Gainesville with another airline. Booking your flights between Gainesville and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Gainesville to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Gainesville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Gainesville to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Gainesville to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Gainesville to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11468 reviews
7.2Comfort
7.9Crew
6.9Entertainment
6.4Food
7.5Boarding
Airline reviews

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

2.0 Mediocresteven, Mar 2026
MIA - CLE
Read more American Airlines reviews

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Flights were constantly delayed. CRW took 50 minutes to get bags

Where do I start!! I was delayed with my flight from Dallas to Tampa. On the way back from Tampa to Dallas the flight was delayed over 4 hours+. I was put on another flight that was also delayed but not as long. Traveling on American Airlines is becoming exhausing.

I didn't end up taking this flight. I got up at 4am for a flight that was supposed to board at 6am - at 5:55am you delayed the flight to 10am. The airport is under construction so I switched to a later flight as I wasn't going to sit in the airport for 4 hours. They said the delay was due to the crew needing rest from a flight coming in late the night before - if that was the case then I think you should have delayed the flight much sooner so that passengers wouldn't get up so early and get to the airport to sit and wait.

The flight attendants and the service is getting worse by the day.

Other than nearly three hour delay for maintenance issues, everything went smooth

why would I bother with this airline and pick seats when I am asked to move for a weight imbalance

Overall good. The pilots and flight attendants are excellent! The equipment was the issue on my First flight as they had to wait for a part to be installed. So the take off was at least 30 minutes later.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

Everything you need to know for your flight from Gainesville to Des Moines

Information on your arrival and departure airports

Gainesville (GNV)
Des Moines (DSM)