VVI

$484 Find Cheap Flights from Houston to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Houston to Santa Cruz de la Sierra departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santa Cruz de la Sierra, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$758
Typical prices: $1,076-$1,016
Multiple Airlines
Thu 5/14Tue 5/26
IAH - VVI • 3 stops
Cheapest one-way
$408
Multiple Airlines
Fri 8/7
IAH - VVI • 2 stops
Top airlines
Cheapest • from $843 (round-trip)
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Houston to Santa Cruz de la Sierra

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Houston to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Houston to Santa Cruz de la Sierra

Thu, May 14 - Tue, May 26
Multiple Airlines Logo
6:00 am - 2:30 am
IAH
-
VVI
19h 30m
3 stops
Multiple Airlines Logo
3:35 am - 11:42 am
VVI
-
IAH
33h 07m
2 stops
$758Multiple Airlines
Thu, May 14 - Wed, May 27
Multiple Airlines Logo
6:00 am - 4:50 am
IAH
-
VVI
21h 50m
2 stops
Multiple Airlines Logo
11:35 pm - 11:42 am
VVI
-
IAH
13h 07m
1 stop
$771Multiple Airlines
Thu, May 14 - Wed, May 27
Multiple Airlines Logo
6:00 am - 4:50 am
IAH
-
VVI
21h 50m
2 stops
Multiple Airlines Logo
11:35 pm - 11:42 am
VVI
-
IAH
13h 07m
1 stop
$773Multiple Airlines
Thu, May 14 - Tue, May 26
Multiple Airlines Logo
4:20 pm - 2:30 am
IAH
-
VVI
33h 10m
2 stops
Multiple Airlines Logo
3:35 am - 1:25 pm
VVI
-
IAH
34h 50m
2 stops
$774Multiple Airlines
Fri, May 15 - Tue, May 19
Multiple Airlines Logo
7:05 am - 2:30 am
IAH
-
VVI
18h 25m
2 stops
Multiple Airlines Logo
3:35 am - 1:25 pm
VVI
-
IAH
34h 50m
2 stops
$786Multiple Airlines
Thu, May 14 - Tue, May 26
Multiple Airlines Logo
6:00 am - 2:30 am
IAH
-
VVI
19h 30m
3 stops
Multiple Airlines Logo
3:35 am - 11:42 am
VVI
-
IAH
33h 07m
2 stops
$793Multiple Airlines
Tue, May 12 - Mon, May 25
Multiple Airlines Logo
5:45 am - 2:30 am
IAH
-
VVI
19h 45m
2 stops
Multiple Airlines Logo
3:35 am - 11:36 pm
VVI
-
IAH
21h 01m
2 stops
$794Multiple Airlines
Thu, May 14 - Tue, May 26
Multiple Airlines Logo
6:00 am - 2:30 am
IAH
-
VVI
19h 30m
3 stops
Multiple Airlines Logo
3:35 am - 12:34 pm
VVI
-
IAH
33h 59m
3 stops
$823Multiple Airlines
Tue, Oct 13 - Tue, Oct 27
LATAM Airlines Logo
5:35 pm - 4:35 am
HOU
-
VVI
34h 00m
2 stops
LATAM Airlines Logo
5:25 am - 12:14 pm
VVI
-
HOU
31h 49m
2 stops
$1,172LATAM Airlines
Wed, Jul 8 - Thu, Jul 16
LATAM Airlines Logo
10:40 am - 4:35 am
HOU
-
VVI
40h 55m
2 stops
LATAM Airlines Logo
5:25 am - 9:45 am
VVI
-
HOU
29h 20m
2 stops
$1,302LATAM Airlines
Booking Insights

KAYAK's insights & trends for Houston to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Houston to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Houston to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Houston to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Houston to Santa Cruz de la Sierra is May, where tickets cost $673 (return) on average. On the other hand, the most expensive months are January and August, where the average cost of round-trip tickets is $1,177 and $831 respectively.

Good to know

Cheapest flight$408
Flight from Houston George Bush Airport to Santa Cruz de la Sierra

When to book flights from Houston to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Houston to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Houston to Santa Cruz de la Sierra

  • What is the cheapest flight from Houston to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Houston to Santa Cruz de la Sierra was $439 for a one-way ticket and $758 for a round-trip.

  • Do I need a passport to fly between Houston and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Houston and on arrival in Santa Cruz de la Sierra.

  • Which airports will I be using when flying from Houston to Santa Cruz de la Sierra?

    Houston has 2 major airports: Houston Hobby and Houston George Bush Intcntl. Santa Cruz de la Sierra Viru Viru Intl is the only airport in Santa Cruz de la Sierra. You’ll usually find the cheapest deals if you fly from Houston George Bush Airport.

  • Which aircraft models fly most regularly from Houston to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Houston to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between Houston and Santa Cruz de la Sierra.

  • How does KAYAK find such low prices on flights from Houston to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Houston to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Houston to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Houston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Houston to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Houston with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Houston to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Houston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Houston to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Houston to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Houston to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1578 reviews
6.8Food
8.1Crew
7.8Boarding
7.4Comfort
6.8Entertainment
Airline reviews

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

2.0 MediocreFiruz, Apr 2026
MEX - PTY
Read more Copa Airlines reviews

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Do not book it’s a scam! They stole $1200 from me

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

It's a long flight and I would have liked better snacks between lunch and the arrival meal. It's fine to have fruit and nuts but I really don't like ramen because it's salty junk soup. I'd suggest sandwiches. They're not expensive nor are they hard to store for a long flight. The FA's had a couple of big services and they were super busy preparing, executing and then cleaning up. Then they disappeared.

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

We had excellent customer service despite the chaos at George Bush airport in Houston!

It isvvery small flight. No leg room . No space to put my personal item at feet.

Didn't make the flight because the first leg of my flight was canceled and the next leg was already booked.

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

The employees at the gate were not communicating, they preferred to give the upgrade to pilots and not to the elite passengers Every flight I more disappointing, clients shooed be priority instead of other employees even if they are pilots, there was plenty room for pilots in economy

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I upgraded to businesses class. Because of that the flight was comfortable.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Everything you need to know for your flight from Houston to Santa Cruz de la Sierra

Information on your arrival and departure airports