SCL

$251 Find Cheap Flights from Houston to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Houston to Santiago departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$571
Typical prices: $720-$1,778
Multiple Airlines
Tue 4/7Fri 4/17
IAH - SCL • 3 stops
Cheapest non-stop
$1,301
United Airlines
Fri 3/20Fri 3/27
IAH - SCL • Non-stop
Top airlines
LATAM Airlines
Cheapest • from $983 (round-trip)
LATAM Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Every day
You can fly direct with United Airlines. Average duration is 9h 05m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top routes
IAH
-
SCL
Cheapest
IAH
-
SCL
Most popular
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Houston to Santiago

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Houston to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Houston to Santiago

Tue, Apr 7 - Fri, Apr 17
Multiple Airlines Logo
5:24 pm - 4:16 am
IAH
-
SCL
33h 52m
3 stops
Multiple Airlines Logo
11:35 am - 3:27 pm
SCL
-
IAH
28h 52m
2 stops
$571Multiple Airlines
Tue, Apr 21 - Fri, Apr 24
Multiple Airlines Logo
11:43 am - 5:30 am
IAH
-
SCL
16h 47m
2 stops
Multiple Airlines Logo
8:40 am - 3:27 pm
SCL
-
IAH
31h 47m
2 stops
$580Multiple Airlines
Sun, Apr 26 - Fri, May 1
Multiple Airlines Logo
9:36 pm - 9:05 pm
IAH
-
SCL
22h 29m
2 stops
Multiple Airlines Logo
10:30 am - 8:08 am
SCL
-
IAH
22h 38m
1 stop
$588Multiple Airlines
Thu, May 21 - Mon, Jun 1
Delta Logo
10:12 am - 6:00 am
HOU
-
SCL
18h 48m
2 stops
Delta Logo
7:35 am - 9:17 am
SCL
-
HOU
26h 42m
2 stops
$985Delta
Tue, May 19 - Wed, May 27
LATAM Airlines Logo
10:12 am - 5:35 am
HOU
-
SCL
18h 23m
2 stops
LATAM Airlines Logo
7:45 pm - 12:11 pm
SCL
-
HOU
17h 26m
2 stops
$990LATAM Airlines
Fri, May 1 - Wed, May 13
LATAM Airlines Logo
5:23 pm - 7:15 am
HOU
-
SCL
12h 52m
1 stop
LATAM Airlines Logo
4:10 am - 11:08 pm
SCL
-
HOU
19h 58m
2 stops
$1,017LATAM Airlines
Fri, May 15 - Mon, Jun 1
Delta Logo
6:00 am - 6:00 am
HOU
-
SCL
23h 00m
2 stops
Delta Logo
8:40 pm - 4:09 pm
SCL
-
HOU
20h 29m
1 stop
$1,025Delta
Fri, May 15 - Mon, Jun 1
Delta Logo
6:00 am - 7:15 am
HOU
-
SCL
24h 15m
1 stop
Delta Logo
8:40 pm - 9:17 am
SCL
-
HOU
13h 37m
1 stop
$1,031Delta
Fri, Apr 24 - Fri, May 1
LATAM Airlines Logo
5:23 pm - 7:15 am
HOU
-
SCL
12h 52m
1 stop
LATAM Airlines Logo
7:45 am - 11:07 pm
SCL
-
HOU
16h 22m
2 stops
$1,057LATAM Airlines
Fri, May 15 - Mon, Jun 1
LATAM Airlines Logo
6:00 am - 7:15 am
HOU
-
SCL
24h 15m
1 stop
LATAM Airlines Logo
8:40 pm - 9:17 am
SCL
-
HOU
13h 37m
1 stop
$1,092LATAM Airlines
Booking Insights

KAYAK's insights & trends for Houston to Santiago flights

Get data-powered insights and trends into flights from Houston to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Houston to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Houston to Santiago departing in April.

What is the cheapest Houston to Santiago flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest return flight from Houston to Santiago costs $1,010 on the route between Houston George Bush Intcntl Airport (IAH) and Santiago (SCL). It is also the most popular route.

What’s the cheapest day of the week to fly from Houston to Santiago?

The average price of all round-trip flights from Houston to Santiago clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santiago on a Thursday and more expensive on a Saturday. On your return trip to Houston, you should consider flying back on a Thursday, and avoid Fridays for better deals.

What is the cheapest month to fly from Houston to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Houston to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Houston to Santiago is April, where tickets cost $720 (return) on average. On the other hand, the most expensive months are June and August, where the average cost of round-trip tickets is $1,588 and $1,536 respectively.

Good to know

Cheapest flight$251
Flight from Houston George Bush Airport to Santiago

When to book flights from Houston to Santiago

Are your dates flexible? Find out the best times to travel from Houston to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Houston to Santiago

  • What is the cheapest flight from Houston to Santiago?

    In the last 3 days, the lowest price for a flight from Houston to Santiago was $251 for a one-way ticket and $580 for a round-trip.

  • Do I need a passport to fly between Houston and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Houston.

  • Which airports will I be using when flying from Houston to Santiago?

    Houston has 2 major airports: Houston Hobby and Houston George Bush Intcntl. Santiago Arturo Merino Benitez is the only airport in Santiago. You’ll usually find the cheapest deals if you fly from Houston George Bush Airport.

  • Which aircraft models fly most regularly from Houston to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Houston to Santiago?

    oneworld, and Star Alliance are the airline alliances operating flights between Houston and Santiago, with oneworld being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Houston to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Houston to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Houston to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Houston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Houston to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Houston with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Houston to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Houston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Houston to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Houston to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Houston to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Houston to Santiago Arturo Merino Benitez

Monday

United Airlines

United Airlines

Tuesday

United Airlines

United Airlines

Wednesday

United Airlines

United Airlines

Thursday

United Airlines

United Airlines

Friday

United Airlines

United Airlines

Saturday

United Airlines

United Airlines

Sunday

United Airlines

United Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Houston

Monday

United Airlines

United Airlines

Tuesday

United Airlines

United Airlines

Wednesday

United Airlines

United Airlines

Thursday

United Airlines

United Airlines

Friday

United Airlines

United Airlines

Saturday

United Airlines

United Airlines

Sunday

United Airlines

United Airlines

See more direct flights

Reviews of the top 4 airlines serving from Houston to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Houston to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Houston to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1921 reviews
8.0Crew
7.3Comfort
6.7Food
7.0Entertainment
7.5Boarding
Airline reviews

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

2.0 MediocreTony, Feb 2026
LGA - ATL
Read more LATAM Airlines reviews

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We were not allowed to carry a bottle of water onto the 8 hour flight.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

I like flying first class, and United has a nice one

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Crew was excellent. This was a relatively long flight though and had very little leg room, and no entertainment.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

We arrived 25 minutes early only to be told our gate was occupied and so we sat for close to 30 minutes to pull into a gate. That’s not an early arrival!

The TSA check in took 1.5 hours to get through in Austin and I missed my flights back to DC

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Flight was on time and there was an empty seat next to me. That makes for a good flight!

We lost a day of our vacation because AA did not get the plane to the gate on time. Even though the gate attendant was very clear that it was not weather related, AA would do nothing because there was some snow that day. They basically said the gate attendant was wrong even though she was on the front line of the situation and they were not.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

Flight was on time and the meal and service were good.

The accessible bathroom should be visible to people in Economy class.

Lexus in first class was absolutely amazing! Beat flight attendant i’ve ever seen.

the plane was so hot!! the air-conditioning was barely blowing. The flight was delayed, and we had to sit on the hot plane before take off for an extended amount of time, waiting on international passengers. Would not have been so bad if it was not so hot. They said it would get better after take off, but it did not.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Everything you need to know for your flight from Houston to Santiago

Information on your arrival and departure airports