SCL

$272 Find Cheap Flights from Houston to Santiago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Houston to Santiago departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$690
Typical prices: $1,653-$3,103
Multiple Airlines
Wed 8/19Mon 8/24
IAH - SCL • 2 stops
Cheapest non-stop
$1,161
United Airlines
Thu 12/10Fri 12/25
IAH - SCL • Non-stop
Top airlines
Cheapest • from $850 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
+1
Top routes
Cheapest
Most popular
Insights
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Flight Deals

Cheap Flights from Houston to Santiago

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Houston to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Houston to Santiago

Wed, Aug 19 - Mon, Aug 24
Multiple Airlines Logo
1:45 pm - 5:14 am
IAH
-
SCL
38h 29m
2 stops
Multiple Airlines Logo
11:00 pm - 9:54 am
SCL
-
IAH
35h 54m
1 stop
$690Multiple Airlines
Wed, Aug 26 - Sun, Aug 30
Multiple Airlines Logo
1:45 pm - 1:50 am
IAH
-
SCL
35h 05m
2 stops
Multiple Airlines Logo
10:25 am - 8:44 am
SCL
-
IAH
23h 19m
1 stop
$711Multiple Airlines
Wed, Aug 26 - Sun, Aug 30
Multiple Airlines Logo
10:49 am - 1:35 pm
IAH
-
SCL
25h 46m
2 stops
Multiple Airlines Logo
5:00 am - 8:44 am
SCL
-
IAH
28h 44m
2 stops
$766Multiple Airlines
Tue, Aug 4 - Tue, Aug 11
Multiple Airlines Logo
7:23 pm - 3:00 am
IAH
-
SCL
54h 37m
2 stops
Multiple Airlines Logo
11:00 pm - 8:24 am
SCL
-
IAH
34h 24m
1 stop
$804Multiple Airlines
Tue, Aug 4 - Tue, Aug 18
Multiple Airlines Logo
7:23 pm - 3:00 am
IAH
-
SCL
54h 37m
2 stops
Multiple Airlines Logo
11:00 pm - 8:44 am
SCL
-
IAH
34h 44m
1 stop
$805Multiple Airlines
Thu, Aug 27 - Wed, Sep 9
LATAM Airlines Logo
10:50 am - 4:40 am
HOU
-
SCL
16h 50m
2 stops
LATAM Airlines Logo
7:55 pm - 1:19 pm
SCL
-
HOU
19h 24m
2 stops
$1,123LATAM Airlines
Mon, Oct 26 - Thu, Nov 12
LATAM Airlines Logo
2:59 pm - 7:40 am
HOU
-
SCL
14h 41m
1 stop
LATAM Airlines Logo
11:10 pm - 12:14 pm
SCL
-
HOU
16h 04m
1 stop
$1,133LATAM Airlines
Thu, Aug 27 - Wed, Sep 9
Delta Logo
10:50 am - 7:15 am
HOU
-
SCL
19h 25m
1 stop
Delta Logo
8:40 pm - 4:31 pm
SCL
-
HOU
21h 51m
1 stop
$1,135Delta
Fri, Sep 25 - Sun, Oct 25
American Airlines Logo
1:56 pm - 8:00 am
HOU
-
SCL
16h 04m
2 stops
American Airlines Logo
10:15 pm - 4:36 pm
SCL
-
HOU
20h 21m
2 stops
$1,140American Airlines
Mon, Dec 14 - Thu, Jan 14
Delta Logo
10:05 am - 6:40 am
HOU
-
SCL
17h 35m
1 stop
Delta Logo
11:48 pm - 9:43 pm
SCL
-
HOU
24h 55m
2 stops
$1,200Delta
Booking Insights

KAYAK's insights & trends for Houston to Santiago flights

Get data-powered insights and trends into flights from Houston to Santiago to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Houston to Santiago flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest return flight from Houston to Santiago costs $1,214 on the route between Houston George Bush Intcntl Airport (IAH) and Santiago (SCL). It is also the most popular route.

What’s the cheapest day of the week to fly from Houston to Santiago?

The average price of all round-trip flights from Houston to Santiago clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santiago on a Friday and more expensive on a Saturday. On your return trip to Houston, you should consider flying back on a Thursday, and avoid Fridays for better deals.

What is the cheapest month to fly from Houston to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Houston to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Houston to Santiago is September, where tickets cost $96 (return) on average. On the other hand, the most expensive months are May and April, where the average cost of round-trip tickets is $1,901 and $1,645 respectively.

Good to know

Cheapest flight$272
Flight from Houston George Bush Airport to Santiago

When to book flights from Houston to Santiago

Are your dates flexible? Find out the best times to travel from Houston to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Houston to Santiago

  • What is the cheapest flight from Houston to Santiago?

    In the last 5 days, the lowest price for a flight from Houston to Santiago was $272 for a one-way ticket and $690 for a round-trip.

  • Do I need a passport to fly between Houston and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Houston.

  • Which airports will I be using when flying from Houston to Santiago?

    Houston has 2 major airports: Houston Hobby and Houston George Bush Intcntl. Santiago Arturo Merino Benitez is the only airport in Santiago. You’ll usually find the cheapest deals if you fly from Houston George Bush Airport.

  • Which aircraft models fly most regularly from Houston to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Houston to Santiago?

    oneworld, and Star Alliance are the airline alliances operating flights between Houston and Santiago, with oneworld being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Houston to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Houston to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Houston to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Houston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Houston to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Houston with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Houston to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Houston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Houston to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Houston to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Houston to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1949 reviews
7.3Comfort
7.5Boarding
6.7Food
7.0Entertainment
8.0Crew
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
ANF - SCL
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

For the expense of first class, the seats could have been nicer and higher tier snacks would have been nice.

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

Packed flight, which makes it tough on crew and boarding staff (and the customers of course). But this was great boarding, clear instructions, etc. Traveling on the weekends are always fraught with danger as you have families and less frequent flyers thus more confusion. But this flight went as planned.

Boarded early, left early, arrived 40 mins early! A win win for me!

I felt scammed. The priced advertised was different than what I paid. I paid the whole some online. I then got a call 20 minutes later saying I need to paid 70 more person. She said the price online is not the guaranteed price.

We had a delay, but thankfully I made it to my connection. Overall it went smooth

Left an hour and a half after the listed time. Up side was it had TV screens on the seat.

It's a long flight and I would have liked better snacks between lunch and the arrival meal. It's fine to have fruit and nuts but I really don't like ramen because it's salty junk soup. I'd suggest sandwiches. They're not expensive nor are they hard to store for a long flight. The FA's had a couple of big services and they were super busy preparing, executing and then cleaning up. Then they disappeared.

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

Nothing, I wont be flying American Airlines again and will not be recommending anyone to fly American Airlines. It was the worst experience flying I've ever had.

Forced to check bags. Crew uninterested in collecting trash. Unclean seats.

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

They changed my seat from one that I had paid for as an upgrade to a regular seat at the last minute.

Very aggressive and unhelpful ground crew. Wanted to check my hand luggage for 3 flights. I had lots of delicate items and computer equipment. So the silly lady wanted to rebook 3 international flights because of a carry on. What nonsense. The baggage handler suggested I put it under my seat - so I did. And this was during the rebooking chaos of the Microsoft crash. She was the most arrogant annoying and aggressive ground staff member I’ve met in 20yrs. (AA flight out of Houston).

Left from gate 30 minutes before flight. Never been late to a flight ever. It says 15 minutes before explicitly on the ticket.

Was as expected. Good leg room on planes - much appreciated.

I know that there is nothing than can be done about rude customers. I did find a couple of them were very rude and inconsiderate In my case the guy who was sitting in the same row as I was in, was trying to watch a movie with no headphones, a crew member did ask him to turn it down or off (thumbs up for that.) Another thing, as we were about to land another young man must have taken his phone off airplane mode was talking with his friends and using fowl language which I found inappropriate to the ppl who were sitting in the same row as him and other ppl around him. I understand how no one wanted to address this person and not get involved. We all just wanted to get home safely with out any incident.

The food service was limited and not good. For a seven hour flight they could do better.

Left 40 mins late; we were fine on our connection but many on our flight were not.

Everything you need to know for your flight from Houston to Santiago

Information on your arrival and departure airports