SCL

$273 Find Cheap Flights from Houston to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Houston to Santiago departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$672
Typical prices: $857-$596
Multiple Airlines
Thu 5/7Wed 5/13
IAH - SCL • 2 stops
Cheapest one-way
$273
Overall average: $290
Multiple Airlines
Mon 5/11
IAH - SCL • 2 stops
Top airlines
Cheapest • from $861 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top routes
Cheapest
Most popular
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Houston to Santiago

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Houston to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Houston to Santiago

Thu, May 7 - Wed, May 13
Multiple Airlines Logo
6:00 am - 4:45 am
IAH
-
SCL
21h 45m
2 stops
Multiple Airlines Logo
12:30 am - 10:16 pm
SCL
-
IAH
22h 46m
2 stops
$672Multiple Airlines
Wed, Apr 22 - Fri, Apr 24
Multiple Airlines Logo
10:09 am - 2:15 pm
IAH
-
SCL
27h 06m
2 stops
Multiple Airlines Logo
6:40 am - 1:24 pm
SCL
-
IAH
31h 44m
2 stops
$680Multiple Airlines
Sat, Apr 25 - Sun, May 3
Multiple Airlines Logo
6:57 pm - 6:55 am
IAH
-
SCL
34h 58m
3 stops
Multiple Airlines Logo
10:55 pm - 7:17 pm
SCL
-
IAH
45h 22m
2 stops
$681Multiple Airlines
Mon, Apr 20 - Fri, Apr 24
Multiple Airlines Logo
7:00 am - 2:15 pm
IAH
-
SCL
30h 15m
2 stops
Multiple Airlines Logo
6:40 am - 8:23 am
SCL
-
IAH
26h 43m
2 stops
$682Multiple Airlines
Mon, Jun 8 - Wed, Jun 24
LATAM Airlines Logo
10:09 am - 5:45 am
HOU
-
SCL
18h 36m
2 stops
LATAM Airlines Logo
8:40 pm - 9:14 am
SCL
-
HOU
13h 34m
1 stop
$1,127LATAM Airlines
Mon, Jun 1 - Thu, Jun 18
LATAM Airlines Logo
5:02 pm - 7:15 am
HOU
-
SCL
13h 13m
1 stop
LATAM Airlines Logo
11:00 pm - 9:53 pm
SCL
-
HOU
23h 53m
2 stops
$1,132LATAM Airlines
Mon, Jun 15 - Mon, Jul 27
LATAM Airlines Logo
5:14 pm - 7:15 am
HOU
-
SCL
13h 01m
1 stop
LATAM Airlines Logo
8:40 pm - 9:45 am
SCL
-
HOU
14h 05m
1 stop
$1,133LATAM Airlines
Mon, Jun 15 - Mon, Jul 27
Delta Logo
10:09 am - 2:05 pm
HOU
-
SCL
26h 56m
2 stops
Delta Logo
11:05 pm - 9:51 pm
SCL
-
HOU
23h 46m
2 stops
$1,135Delta
Wed, Jul 8 - Sun, Jul 19
LATAM Airlines Logo
10:40 am - 6:00 am
HOU
-
SCL
18h 20m
2 stops
LATAM Airlines Logo
4:30 pm - 9:51 pm
SCL
-
HOU
30h 21m
2 stops
$1,138LATAM Airlines
Wed, Jun 3 - Wed, Jun 17
Delta Logo
6:00 am - 5:35 am
HOU
-
SCL
22h 35m
2 stops
Delta Logo
10:30 am - 12:13 pm
SCL
-
HOU
26h 43m
2 stops
$1,140Delta
Booking Insights

KAYAK's insights & trends for Houston to Santiago flights

Get data-powered insights and trends into flights from Houston to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Houston to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Houston to Santiago departing in May.

What is the cheapest Houston to Santiago flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest return flight from Houston to Santiago costs $1,401 on the route between Houston George Bush Intcntl Airport (IAH) and Santiago (SCL). It is also the most popular route.

What’s the cheapest day of the week to fly from Houston to Santiago?

The average price of all round-trip flights from Houston to Santiago clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santiago on a Thursday and more expensive on a Saturday. On your return trip to Houston, you should consider flying back on a Thursday, and avoid Fridays for better deals.

What is the cheapest month to fly from Houston to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Houston to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Houston to Santiago is May, where tickets cost $847 (return) on average. On the other hand, the most expensive months are June and April, where the average cost of round-trip tickets is $1,656 and $1,654 respectively.

Good to know

Cheapest flight$273
Flight from Houston George Bush Airport to Santiago

When to book flights from Houston to Santiago

Are your dates flexible? Find out the best times to travel from Houston to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Houston to Santiago

  • What is the cheapest flight from Houston to Santiago?

    In the last 3 days, the lowest price for a flight from Houston to Santiago was $273 for a one-way ticket and $672 for a round-trip.

  • Do I need a passport to fly between Houston and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Houston.

  • Which airports will I be using when flying from Houston to Santiago?

    Houston has 2 major airports: Houston Hobby and Houston George Bush Intcntl. Santiago Arturo Merino Benitez is the only airport in Santiago. You’ll usually find the cheapest deals if you fly from Houston George Bush Airport.

  • Which aircraft models fly most regularly from Houston to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Houston to Santiago?

    oneworld, and Star Alliance are the airline alliances operating flights between Houston and Santiago, with oneworld being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Houston to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Houston to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Houston to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Houston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Houston to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Houston with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Houston to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Houston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Houston to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Houston to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Houston to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1909 reviews
7.3Comfort
7.0Entertainment
7.5Boarding
6.7Food
8.0Crew
Airline reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

10.0 ExcellentYelen, Mar 2026
ATL - TPA
Read more LATAM Airlines reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We were not allowed to carry a bottle of water onto the 8 hour flight.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

We had excellent customer service despite the chaos at George Bush airport in Houston!

It isvvery small flight. No leg room . No space to put my personal item at feet.

Didn't make the flight because the first leg of my flight was canceled and the next leg was already booked.

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

I like flying first class, and United has a nice one

Seat was VERY uncomfortable. Flight was delayed and then boarded slowly. The crew was super helpful with boarding and supporting maximizing the luggage in the overhead.

The flight changed gates multiple times and flight had to be delayed multiple times

Delayed for mechanical and no updates on what was happening and how long the delay might be.

On the return flight, arriving in Denver we sat on the tarmac in Denver for over 20 minutes.

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Mostly good. The WiFi wasn’t working so that was not great.

I rated the experience "mediocre" because of the 2 hour delay in take off. This is the 4th flight from DFW on AA where there was a delay and in one of the instances (after 13 delays), the flight was cancelled. I understand weather but for the March 18th flight, there was no weather issue in Dallas or Detroit. I called Concierge Key and they were wonderful, booking me on a later flight in case my flight was cancelled. I have flown with American for many years and never has there been this consistent pattern of delays. Very disappointing.

As a first class customer, there was no power the entire flight which limited my ability to work. I find this unacceptable. The first 11 rows on the left side of the plan were out. I was only offered the option to charge my phone which was not the issue because my laptop was out of power. I asked if there was anything that can be done for me, and the answer was, "no". I was not offered any type of compensation for this AA problem which caused me unnecessary stress due to inability to address business issues on an already challenging travel day. Flight attendants tried to reset the power once but that was the extent of their support. Very disappointing for the lack of expected services on a flight. Please contact me with customer focused response to this complaint.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

Everything you need to know for your flight from Houston to Santiago

Information on your arrival and departure airports