IAH - SCL

$251 Find Cheap Flights from Houston George Bush Airport to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from George Bush Intcntl to Santiago departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Houston to Santiago, as well as popular online travel agencies
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41 299 237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$571
Typical prices: $720-$1,778
Multiple Airlines
Tue 4/7Fri 4/17
IAH - SCL • 3 stops
Cheapest non-stop
$1,301
United Airlines
Fri 3/20Fri 3/27
IAH - SCL • Non-stop
Nonstop flights
Every day
You can fly direct with United Airlines. Average duration is 9h 05m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top layover airports
Mexico City (MEX)
Cheapest • Avg $1,488 (round-trip)
Panama City (PTY)
Shortest trip • 11h 47m (one-way)
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 47% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from George Bush Intcntl to Santiago (IAH-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from George Bush Intcntl to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from George Bush Intcntl to Santiago

Tue, Apr 7 - Fri, Apr 17
Multiple Airlines Logo
5:24 pm - 4:16 am
IAH
-
SCL
33h 52m
3 stops
Multiple Airlines Logo
11:35 am - 3:27 pm
SCL
-
IAH
28h 52m
2 stops
$571Multiple Airlines
Tue, Apr 21 - Fri, Apr 24
Multiple Airlines Logo
11:43 am - 5:30 am
IAH
-
SCL
16h 47m
2 stops
Multiple Airlines Logo
8:40 am - 3:27 pm
SCL
-
IAH
31h 47m
2 stops
$580Multiple Airlines
Sun, Apr 26 - Fri, May 1
Multiple Airlines Logo
9:36 pm - 9:05 pm
IAH
-
SCL
22h 29m
2 stops
Multiple Airlines Logo
10:30 am - 8:08 am
SCL
-
IAH
22h 38m
1 stop
$588Multiple Airlines
Tue, Apr 7 - Fri, Apr 17
Multiple Airlines Logo
5:24 pm - 4:16 am
IAH
-
SCL
33h 52m
3 stops
Multiple Airlines Logo
11:35 am - 6:00 pm
SCL
-
IAH
31h 25m
3 stops
$593Multiple Airlines
Mon, Apr 13 - Sun, Apr 19
Multiple Airlines Logo
5:24 pm - 5:30 am
IAH
-
SCL
35h 06m
2 stops
Multiple Airlines Logo
8:30 am - 7:26 pm
SCL
-
IAH
35h 56m
2 stops
$598Multiple Airlines
Fri, Apr 24 - Sun, May 3
Multiple Airlines Logo
4:30 pm - 9:05 pm
IAH
-
SCL
27h 35m
2 stops
Multiple Airlines Logo
11:00 pm - 8:08 am
SCL
-
IAH
34h 08m
1 stop
$600Multiple Airlines
Fri, Apr 17 - Tue, Apr 21
Multiple Airlines Logo
8:50 pm - 9:05 pm
IAH
-
SCL
23h 15m
2 stops
Multiple Airlines Logo
10:30 am - 10:49 pm
SCL
-
IAH
13h 19m
1 stop
$608Multiple Airlines
Wed, Apr 15 - Tue, Apr 21
Multiple Airlines Logo
11:43 am - 5:30 am
IAH
-
SCL
16h 47m
2 stops
Multiple Airlines Logo
10:30 am - 10:49 pm
SCL
-
IAH
13h 19m
1 stop
$609Multiple Airlines
Wed, Apr 15 - Fri, Apr 24
Multiple Airlines Logo
11:43 am - 5:30 am
IAH
-
SCL
16h 47m
2 stops
Multiple Airlines Logo
8:40 am - 3:27 pm
SCL
-
IAH
31h 47m
2 stops
$610Multiple Airlines
Sat, Apr 25 - Sun, May 3
Multiple Airlines Logo
11:43 am - 11:05 am
IAH
-
SCL
22h 22m
3 stops
Multiple Airlines Logo
11:00 pm - 8:08 am
SCL
-
IAH
34h 08m
1 stop
$611Multiple Airlines
Booking Insights

KAYAK's insights & trends for George Bush Intcntl to Santiago flights

Get data-powered insights and trends into flights from George Bush Intcntl to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Houston George Bush Intcntl Airport to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Houston George Bush Intcntl Airport to Santiago departing in April.

What’s the cheapest day of the week to fly from Houston George Bush Airport to Santiago?

The average price of all round-trip flights from Houston George Bush Intcntl Airport to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Houston George Bush Airport to Santiago, you should consider leaving on a Thursday and avoid Saturdays if you are looking for the best rates. For your return to Houston George Bush Airport, you’ll find the best rates on Thursdays and the most expensive ones on Fridays.

What is the cheapest month to fly from Houston George Bush Intcntl Airport to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Houston George Bush Intcntl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Houston George Bush Intcntl Airport to Santiago is May, where tickets cost $631 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is $1,563 and $1,403 respectively.

Can I save money by flying with a layover from Houston George Bush Intcntl Airport to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $1,135 on average.

Good to know

Low seasonApril
Cheapest flight$251
Best time to beat the crowds but there is an average 5% increase in price.
Flight from Houston George Bush Airport to Santiago

When to book flights from George Bush Intcntl to Santiago

Are your dates flexible? Find out the best times to travel from George Bush Intcntl to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Houston George Bush Airport to Santiago flights

  • What is the cheapest flight from Houston George Bush Intcntl Airport to Santiago?

    In the last 3 days, the lowest price for a flight from Houston George Bush Intcntl Airport to Santiago was $251 for a one-way ticket and $580 for a round-trip.

  • Do I need a passport to fly between Houston George Bush Airport and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Houston George Bush Airport and on arrival in Santiago.

  • Which airlines offer Wi-Fi service onboard planes from Houston George Bush Airport to Santiago?

    Only JetBlue offers inflight Wi-Fi service on the Houston George Bush Airport to Santiago flight route.

  • Which aircraft models fly most regularly from Houston George Bush Airport to Santiago?

    The Boeing 777 is the aircraft model that flies most regularly on the Houston George Bush Airport to Santiago flight route.

  • Which airline alliances offer flights from Houston George Bush Airport to Santiago?

    oneworld, and Star Alliance are the airline alliances operating flights between Houston George Bush Airport and Santiago, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Houston George Bush Airport to Santiago?

    There are nonstop flights from Houston George Bush Airport to Santiago on a daily basis.

  • Which is the best airline for flights from Houston to Santiago, LATAM Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Houston to Santiago are LATAM Airlines and United Airlines. With an average price for the route of $1,153 and an overall rating of 7.5, LATAM Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $1,208 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Houston George Bush Airport to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Houston George Bush Airport to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Houston George Bush Airport to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Houston George Bush Airport is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Houston George Bush Airport to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Houston George Bush Airport with another airline. Booking your flights between Houston George Bush Airport and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Houston George Bush Airport to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Houston George Bush Airport up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Houston George Bush Intcntl Airport to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $1,010 or less round-trip.

Prefer to fly direct from Houston George Bush Airport to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Houston George Bush Intcntl to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Houston George Bush Intcntl Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Houston George Bush Intcntl to Santiago Arturo Merino Benitez

Monday

United Airlines

United Airlines

Tuesday

United Airlines

United Airlines

Wednesday

United Airlines

United Airlines

Thursday

United Airlines

United Airlines

Friday

United Airlines

United Airlines

Saturday

United Airlines

United Airlines

Sunday

United Airlines

United Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Houston George Bush Intcntl

Monday

United Airlines

United Airlines

Tuesday

United Airlines

United Airlines

Wednesday

United Airlines

United Airlines

Thursday

United Airlines

United Airlines

Friday

United Airlines

United Airlines

Saturday

United Airlines

United Airlines

Sunday

United Airlines

United Airlines

See more direct flights

Reviews of the top 4 airlines serving from George Bush Intcntl to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Houston to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from George Bush Intcntl to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1921 reviews
6.7Food
7.0Entertainment
8.0Crew
7.5Boarding
7.3Comfort
Airline reviews

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

2.0 MediocreTony, Feb 2026
LGA - ATL
Read more LATAM Airlines reviews

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

I like flying first class, and United has a nice one

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Crew was excellent. This was a relatively long flight though and had very little leg room, and no entertainment.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

We arrived 25 minutes early only to be told our gate was occupied and so we sat for close to 30 minutes to pull into a gate. That’s not an early arrival!

The TSA check in took 1.5 hours to get through in Austin and I missed my flights back to DC

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Flight was on time and there was an empty seat next to me. That makes for a good flight!

We lost a day of our vacation because AA did not get the plane to the gate on time. Even though the gate attendant was very clear that it was not weather related, AA would do nothing because there was some snow that day. They basically said the gate attendant was wrong even though she was on the front line of the situation and they were not.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

Flight was on time and the meal and service were good.

The accessible bathroom should be visible to people in Economy class.

Lexus in first class was absolutely amazing! Beat flight attendant i’ve ever seen.

the plane was so hot!! the air-conditioning was barely blowing. The flight was delayed, and we had to sit on the hot plane before take off for an extended amount of time, waiting on international passengers. Would not have been so bad if it was not so hot. They said it would get better after take off, but it did not.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Everything you need to know for your flight from George Bush Intcntl to Santiago

Information on your arrival and departure airports