$36 Find Cheap Flights from Indianapolis to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Indianapolis to South Carolina departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Indianapolis to South Carolina.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Indianapolis to South Carolina.
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Indianapolis to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charlestonnonstop$77
Myrtle Beach
Myrtle Beachnonstop$154
Greenville
Greenville2 stops$240
Columbia
Columbia1 stop$265
Charlotte
Charlotte1 stop$147
Charleston
Charlestonnonstop$77
Myrtle Beach
Myrtle Beachnonstop$154
Greenville
Greenville2 stops$240
Columbia
Columbia1 stop$265
Charlotte
Charlotte1 stop$147

Book Cheap Indianapolis to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Indianapolis to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Indianapolis to South Carolina

Mon, Jun 8 - Mon, Jun 15
Allegiant Air Logo
6:47 pm - 8:35 pm
IND
-
CHS
1h 48mnonstop
Allegiant Air Logo
9:30 pm - 11:26 pm
CHS
-
IND
1h 56mnonstop
$77Allegiant Air
Mon, Jun 8 - Mon, Jun 15
Allegiant Air Logo
6:47 pm - 8:35 pm
IND
-
CHS
1h 48mnonstop
Allegiant Air Logo
9:30 pm - 11:26 pm
CHS
-
IND
1h 56mnonstop
$82Allegiant Air
Mon, Jun 15 - Fri, Jun 19
Allegiant Air Logo
6:52 pm - 8:40 pm
IND
-
CHS
1h 48mnonstop
Allegiant Air Logo
9:30 pm - 11:26 pm
CHS
-
IND
1h 56mnonstop
$86Allegiant Air
Wed, Aug 19 - Wed, Aug 26
Delta Logo
5:26 pm - 10:07 pm
IND
-
CLT
4h 41m
1 stop
Delta Logo
6:45 am - 10:45 am
CLT
-
IND
4h 00m
1 stop
$147Delta
Tue, Jun 9 - Fri, Jun 12
Delta Logo
8:05 am - 1:35 pm
IND
-
CLT
5h 30m
1 stop
Delta Logo
5:30 am - 9:02 am
CLT
-
IND
3h 32m
1 stop
$152Delta
Thu, Jun 11 - Wed, Jun 17
American Airlines Logo
6:20 am - 2:40 pm
IND
-
CAE
8h 20m
1 stop
American Airlines Logo
3:26 pm - 9:37 pm
CAE
-
IND
6h 11m
1 stop
$265American Airlines
Tue, Jul 28 - Tue, Jul 28
United Airlines Logo
7:05 am - 2:14 pm
IND
-
SAV
7h 09m
1 stop
United Airlines Logo
7:15 pm - 11:59 pm
SAV
-
IND
4h 44m
1 stop
$282United Airlines
Thu, Jul 23 - Mon, Jul 27
American Airlines Logo
8:50 am - 2:42 pm
IND
-
CAE
5h 52m
1 stop
American Airlines Logo
8:30 pm - 12:10 am
CAE
-
IND
3h 40m
1 stop
$289American Airlines
Tue, Jul 28 - Tue, Jul 28
Southwest Logo
5:05 am - 12:40 pm
IND
-
SAV
7h 35m
2 stops
Southwest Logo
6:35 pm - 11:25 pm
SAV
-
IND
4h 50m
1 stop
$292Southwest
Wed, Sep 2 - Sat, Sep 5
United Airlines Logo
7:00 am - 1:40 pm
IND
-
CAE
6h 40m
1 stop
United Airlines Logo
7:54 pm - 11:56 pm
CAE
-
IND
4h 02m
1 stop
$311United Airlines
Booking Insights

KAYAK's insights & trends for Indianapolis to South Carolina flights

Get data-powered insights and trends into flights from Indianapolis to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Indianapolis to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Indianapolis to South Carolina departing in June.

What is the cheapest Indianapolis to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Indianapolis found in the last 72 hours was to Charleston, at $92 round-trip. The most popular route is from Indianapolis (IND) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $92.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Indianapolis to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $128 on average. Morning departures are around 1% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $137.

Can I save money by flying with a layover from Indianapolis to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $260, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Indianapolis to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Indianapolis to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Indianapolis to South Carolina is August, when tickets cost $41 (return) on average. On the other hand, the most expensive months are April and January, when the average cost of round-trip tickets is $270 and $185 respectively.

How far in advance should I book a flight from Indianapolis to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Indianapolis to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Indianapolis to South Carolina, you should book around 4 weeks before departure, which saves you about 58% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$36
Most popular time to fly and prices are also 9% lower on average.
Flight from Indianapolis to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Indianapolis to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Indianapolis to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Indianapolis to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Indianapolis to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Indianapolis to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Indianapolis to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Indianapolis to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Indianapolis to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Indianapolis to the following destinations at these prices or less: Charlotte $194 one-way - $365 round-trip

Reviews of the top 5 airlines serving from Indianapolis to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Indianapolis to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Indianapolis to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4289 reviews
8.1Boarding
8.0Comfort
7.5Entertainment
8.6Crew
7.0Food
Airline reviews

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

2.0 MediocreAnonymous, May 2026
MCO - MDW
Read more Southwest reviews

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

I'm glad it wasn't only 75% full because I could get a good seat

if I was good. Not happy that I have to pay extra money to get the seat I need for lake room, but I guess that’s a sign of the times.

Seats were very comfortable. They tilted back. Drinks and snacks were free and served 3 times. Attendants were awesome.

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

Truly terrible. Will never willingly fly southwest again. Seats are worse than before they switched to assigned seating. One flight attendant was the opposite of helpful (rude, unhelpful, dismissive, and as my stranger seatmate said unprompted: a total prick). This caused me, 15 minutes into the flight, to book an alternate return flight home on a competing airline (first class 1.2k purchase instead of my existing planned flight) just so I would not have to ever be on that aircraft, with that terrible service person, with those horrific seats ever again.

Not having a five hour delay with little notice! The crew was very kind, though, and just as tired as we passengers were. The flight didn't depart until nearly 1 am...and no reason was ever given.

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

First time I've had to use the disabled accommodations. And I could not have had a better experience with Southwest, i was having trouble getting from one terminal to another due to my heart failure. And the next thing I know a Southwest agent had made sure. I had a wheelchair at all my flights. Can't thank them enough.

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

Seats were very uncomfortable and being charged for snacks and water.........

Allegiant actually impressed me, original inbound flight from PBG was so late they gave us a bird inbound from Des Moines and only left 1h late and gained 40 minutes back in the air. Comfortable flight with no frills but no complaints.

Flight was delayed. Crew was good but hot coffee was not available.

Great. No choice for n/a. No food or entertainment options

No food is available without purchasing it and there is no in-flight entertainment. Both of these are OK because we got an inexpensive flight from Allegiant and, otherwise, our experience was excellent.

just had water and there was plenty of leg & seat room. But then i don't weight 220#s!!

Not totally their fault- screaming kids that had zero parent intervention.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

I had a fantastic experience with Allegiant. I had wheelchair assistance and they helped me find my luggage and brought me to my car. Even loaded my luggage. Wonderful service!! Thank you Allegiant!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

Fine. Nothing to write home about. The plane left on time, and arrived on time.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

Seat comfort was poor (no lumbar or lower back support).

The airplane seats were spacious and comfortable, and the flight attendants were friendly and attentive. The food was delicious like never before. The blankets and toiletries were thoughtfully provided. The captain's navigation was steady and reliable. In short, having flown with Starlux, I won't consider any other airline next time.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

The small flights with Valet Luggage has a poor service

It would have been better IF IT HAD NOT BEEN CANCELED!!!!

There was no flight. Spirit went bankrupt Right before my departure and kayak did not refund me any money. I would like my refund kayak. How can I get it? Please let me know. Thank you

Flights were canceled due to airline shutting down and haven’t received a reimbursement. Had to book last minute new flights which were expensive

My flight was canceled the morning of the flight. I had to rebook a flight with a different airline that cost me $900 out of my pocket

Had a flight change had to get a credit.will I get my money back.

Shut down without prior notice End up with spending lots of extra $$$

There was a crack in my window seal. And Spirit is now closed forever.

The company went out of business and now I'm stuck in Ft. Lauderdale. Would not recommend.

Spirit changed flight times by 12 hours with coming and going so I refunded tickets and drove

The airline cancel mi flight, lost a lot of money!!!

Everything you need to know for your flight from Indianapolis to South Carolina

Information on your arrival and departure airports