$49 Find Cheap Flights from Indiana to South Carolina

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Low seasonJanuary
High seasonAugust
Cheapest flight$49
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Cincinnati to Myrtle Beach

FAQs for booking flights from Indiana to South Carolina

  • How does KAYAK find such low prices on flights from Indiana to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Indiana to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Indiana to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Indiana to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Indiana to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Indiana to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Indiana to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Indiana to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • Which is the cheapest airport to fly into in South Carolina?

    Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in South Carolina is Charleston Airport (CHS), with an average flight price of $49.

  • What is the cheapest day to fly to South Carolina?

    Based on KAYAK data, the cheapest day to fly to South Carolina is Wednesday where round-trip tickets can be as cheap as $45. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $372 on average.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $130 on average. Morning departures are around 25% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally at night, which is peak travel time and where the average cost of a ticket is $326.

  • What is the cheapest flight to South Carolina?

    The cheapest ticket to South Carolina from Indiana found in the last 72 hours was to Charleston, at $45 round-trip. The most popular route is Fort Wayne (FWA) to Myrtle Beach (MYR) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $80.

  • What is the cheapest month to fly from Indiana to South Carolina?

    The cheapest month for flights from Indiana to South Carolina is June, when tickets cost $179 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $411 and $402 respectively.

  • How far in advance should I book a flight from Indiana to South Carolina?

    To get a below average price on the flight from Indiana to South Carolina, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

  • How long is the flight to South Carolina?

    An average nonstop flight from Indiana to South Carolina takes 2h 50m, covering a distance of 557 miles. The shortest route is Louisville (SDF) to Myrtle Beach (MYR) with an average flight time of 1h 24m.

  • What are the most popular destinations in South Carolina?

    Based on KAYAK flight searches, the most popular destination is Charlotte (26% of total searches to South Carolina). The next most popular destinations are Savannah (22%) and Charleston (21%). Searches for flights to Myrtle Beach (14%), to Greenville (7%) and to Hilton Head Island (5%) are also popular.

Reviews of the top 5 airlines serving from Indiana to South Carolina

 
Need help choosing which airline to fly with from Indiana to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7963 reviews
8.5Crew
7.3Food
8.2Boarding
7.9Entertainment
7.9Comfort
Airline reviews

I like for how they process during check in. It was very smoothly.

10.0 ExcellentAbdulla, Jun 2025CMH - JFK
Read more Delta reviews

I like for how they process during check in. It was very smoothly.

The flight was scheduled for 2:30 PM. Early in the morning we got a text message saying the flight was delayed and rescheduled for 3:00 PM. We got to the airport with that in mind. Then we got a message during check-in at the flight was rescheduled again for 2:30 PM. We almost missed our flight. In fact, our bags Were told that they would not make it. At the end, everything worked out. But it is very stressful.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Great overall. There was a bit of turbulence so they could only serve water because too much turbulence for the carts. Was glad they prioritized safety though

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

Great service. Flight was delayed while we sat on the runway for a couple of hours. Weather related. Staff made is very bearable. The steward servicing the first class cabin was exceptional. Thank you! 💗

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

Gate agent did not hold flight for connection, provided no assistance to get new flight

Evidently, my seat had the only broken TV. I couldn’t plug it in, get it to come on, or watch anything, and of course, no one could fix it while we were on the plane. The service was good and the boarding was quick

United airlines, mediocre at best. No issues , nothing great . Worked for me

it was so bad. I tried to board my flight from vancouver to saskatoon. And to my surprise they did not board me cause the flight was changed and no email was send to me. and on my boarding pass which i got from seattle says different flight. I did not knew anyone from Vancouver, air canada crew was rude, i asked for today flight but they were rude and i had early morning dental appointment in saskatoon. I was so much in pain and my whole day is wasted today. and i suffered alot. They did provide me hotel but they did not provide me any food. I am really really disappointed first time had so bad experience with air canada. I may think twice to book it again. If i can get any reply or any composition that would be great. Thanks

It was fine, definitely older planes with no charging or anything. There’s no entertainment set up on board, but it is nice that they allow you to access the in flight entertainment from your phone without having to pay for the Wi-Fi and they do offer free texting.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

I was supposed to be on business class at first class from Denver back to Miami due to weather changes. I missed my connection and it’s put on a flight to Fort Lauderdale. Instead of honoring my business class/1st class ticket, they put me in coach, but there were two first class seats open. I think it’s absolutely disgusting that I paid for first class $1300 ticket and they put me in economy and they had to open seats available and I have still not been refunded the difference. I ended up having to eat a snack box instead of the meal I was supposed to get and did not get home till 2 AM so I think that’s a little pathetic that I had to live off crackers for dinner And my poor dog ate some cheese and salami. Oh yes, apparently when they switched me to the new flight they forgot to mention I had a service dog

Tight! Seats are not designed for those of us who wear extra-large clothes.

The non-stop flight from Grand Rapids was excellent. I neither expected or needed a budget flight and Allegiant made the trip easy and for an affordable price, Arriving at the Mesa Airport (AZA) is a delight compared to the international airport. For our return flight, we were able to arrive 75 minutes before the flight, return the rental car, check our bag and make it to the gate in plenty of time. That would never happen at most airports.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

They boarded passengers that sat in the back of the plane first, making boarding very efficient.

I didn't even take this flight. My plans changed and I couldn't get ahold of customer service and the website kept breaking down during the attempt to change the flight. I wound up taking another airline entirely and eating the cost.

The worst flying experience ever 3 delays. No accommodations. Had to deboard the plane after being delayed.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

I’m impressed that we were on time in Sacramento after having a late departure in Newark and our made it. The staff was friendly and warm.

Cramped seats. FAA should make airlines have more legroom, for even short people complain

5.5 hour delay with no explanation on why, along with no proactive effort to reaccomodate me.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

Most miserable flight ever. We waited almost 2 hours on the runway because the flight was oversold. American offered $1200 credit. Then there was some nonsense about weight distribution. Ridiculous. No food for 8 plus hours on the flight. I will be writing a letter.

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

The plane was probably full boarding was easy. We were able to check our carry-on luggage for free. It was a return flight through Philly to LA. Never saw a stewardess do a demonstration of emergency Procedures. I think my flight was pretty full

Plane, flight, crew, captain were all great. The first flight had a Chipotle box lunch...delicious.

It was absolutely awesome. The crew was welcoming to all, not just the first class. They were full of energy. The in-cabin music was an excellent choice, not boring like most airlines. We were ready for takeoff ahead of time. Pilots were great. Smooth takeoff and landing. The plane was beautiful and nicely cleaned. This was truly a fantastic flight. I fly Delta and American all the time. I was apprehensive about Spirit. I will definitely be looking for Spirit first. Thanks for a great experience.

Didn't like size of seats. Found charges for checked luggage and carry on too high

Great! We boarded on time! Everything went so smoothly! The flight was so smooth

Spirit gets you there; it's no worse than any other aircraft, all things considered. (It's not like everyone else is such a hero). But - holy moses - do they nickel and dime you to absolutely every nickel - I was really expecting to have to pay to use the bathroom. And when the captain comes on with a 5 minute sales pitch about getting "points", that was like something on Bizarro world. Other than that, everyone else was professional and worked hard to get us from point A to point B. I'm not loving all the "self-service" stuff but there it is - just when the machines don't work you don't have anyone to talk to.

Boarding was a breeze, however, two of the flights that I boarded with Spirit did not have Wi-Fi available.

Seats uncomfortable, hard to check luggage, etc. It was like the last flight out of Hanoi

Need screens for tv/movies. Seats are more cramped than any other airlines. Seats are hard. They don’t recline. And in flight time should not be used for sales pitches.

Good experience except for the drunk woman who was with a child. Sad

The ease of booking the flight was very good. Speaking with customer service was also good. However, the crew people are unfriendly and unwelcoming which I found this as unprofessional. As far as comfort it was mediocre. This was my first time flying Spirit and I chose them because of the flight times met my needs and my budget. However, I would be reluctant to fly on Spirit again. In addition, if the crew were more friendly and at least appeared somewhat happy and welcoming personally it would probably make the experience of flying with Spirit better.

Tell them to chose a better, less bumpy route :( my seat had no window all the way at the end 😔

Book cheap flights from Indiana to South Carolina

Recent round-trip flight deals

8/1Fri
nonstopAllegiant Air
1h 30mCVG-MYR
8/4Mon
nonstopAllegiant Air
1h 38mMYR-CVG
$58
7/18Fri
nonstopAllegiant Air
1h 30mCVG-MYR
7/21Mon
nonstopAllegiant Air
1h 38mMYR-CVG
$62
8/2Sat
nonstopSpirit Airlines
2h 00mORD-MYR
8/9Sat
nonstopSpirit Airlines
2h 25mMYR-ORD
$101
7/10Thu
nonstopSpirit Airlines
2h 00mORD-MYR
7/13Sun
nonstopSpirit Airlines
2h 25mMYR-ORD
$104
8/16Sat
nonstopAmerican Airlines
2h 10mORD-CLT
8/23Sat
nonstopAmerican Airlines
2h 18mCLT-ORD
$141
8/28Thu
nonstopAmerican Airlines
2h 03mORD-CLT
9/2Tue
nonstopAmerican Airlines
2h 08mCLT-ORD
$142
10/22Wed
nonstopUnited Airlines
2h 16mORD-CLT
10/26Sun
nonstopUnited Airlines
2h 22mCLT-ORD
$150
8/4Mon
nonstopUnited Airlines
2h 12mORD-CLT
8/4Mon
nonstopUnited Airlines
2h 36mCLT-ORD
$157
8/28Thu
1 stopDelta
5h 59mMDW-CLT
9/2Tue
1 stopDelta
4h 41mCLT-MDW
$197
9/20Sat
1 stopDelta
4h 19mORD-CLT
9/27Sat
1 stopDelta
5h 22mCLT-ORD
$197

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Recent one-way flight deals

7/18Fri
nonstopAllegiant Air
1h 30mCVG-MYR
$49
6/30Mon
nonstopAllegiant Air
1h 36mCVG-SAV
$49
7/13Sun
nonstopSpirit Airlines
2h 00mORD-MYR
$51
8/12Tue
nonstopUnited Airlines
2h 10mORD-CLT
$71
8/24Sun
nonstopAmerican Airlines
2h 10mORD-CLT
$72
7/8Tue
1 stopSpirit Airlines
10h 26mORD-MYR
$79
8/4Mon
nonstopUnited Airlines
2h 12mORD-CLT
$79
8/6Wed
1 stopAmerican Airlines
5h 24mCVG-MYR
$80
8/5Tue
1 stopDelta
5h 26mMDW-CLT
$99
8/5Tue
1 stopDelta
3h 41mORD-CLT
$99

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Last minute flights from Indiana to South Carolina

Last minute flight, train and bus deals

6/20Fri
nonstopAllegiant Air
1h 28mCVG-MYR
6/23Mon
nonstopAllegiant Air
1h 38mMYR-CVG
$139
6/20Fri
nonstopAllegiant Air
1h 36mCVG-SAV
6/28Sat
nonstopAllegiant Air
1h 42mSAV-CVG
$142
6/21Sat
multi-stopSpirit Airlines
10h 26mORD-MYR
6/28Sat
nonstopSpirit Airlines
2h 24mMYR-ORD
$150
6/21Sat
multi-stopSpirit Airlines
7h 36mORD-MYR
6/28Sat
nonstopSpirit Airlines
2h 24mMYR-ORD
$160
6/22Sun
multi-stopAmerican Airlines
5h 52mORD-GSP
7/21Mon
nonstopAmerican Airlines
2h 08mGSP-ORD
$281
6/21Sat
multi-stopDelta
3h 34mORD-GSP
6/22Sun
multi-stopDelta
4h 09mGSP-ORD
$286
6/19Thu
nonstopAmerican Airlines
1h 44mORD-GSP
6/21Sat
nonstopAmerican Airlines
2h 13mGSP-ORD
$288
6/19Thu
multi-stopDelta
8h 30mORD-GSP
6/21Sat
multi-stopDelta
4h 03mGSP-ORD
$308
6/20Fri
nonstopUnited Airlines
2h 07mORD-GSP
6/21Sat
multi-stopUnited Airlines
4h 44mGSP-ORD
$368
6/20Fri
nonstopUnited Airlines
1h 57mORD-GSP
6/21Sat
nonstopUnited Airlines
2h 21mGSP-ORD
$375

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Everything you need to know for your flight to South Carolina

Cabin class types available on flights to Indiana

Cabin classes available on flights to Indiana. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

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