$331 Find Cheap Flights from Jacksonville to Panama - Compare and Save

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1 adult, Economy, 0 bags

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Price, demand and travel trends for Jacksonville to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Jacksonville to Panama right now?

The cheapest fare from Jacksonville to Panama in the last week was $641 round-trip, to Panama City Tocumen Intl (PTY).

What’s the cheapest month to fly from Jacksonville to Panama?

April is the cheapest time of year to fly, with average fares of $555. Prices are highest in February, when average flight costs increase to around $817.

Which airport in Panama is the cheapest to fly to from Jacksonville?

All flights from Jacksonville to Panama arrive at Panama City Tocumen Intl (PTY). On average, round-trip fares are around $588.

What’s the cheapest day to fly from Jacksonville to Panama?

Saturday tends to be the cheapest day to fly from Jacksonville to Panama, while Friday is the most expensive. Fares run about 20% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from Jacksonville to Panama?

Data from the past 12 months shows it's cheapest to fly to Panama during the evening with average prices of $457. The morning is the most expensive time to fly, with average prices of $588.

Key details for Jacksonville to Panama flights

Low season

February

Cheapest flight

$331
Beat the crowds with an average 32% drop in travelers.
The most popular month to fly with an average 64% increase in travelers.
One-way flight from Jacksonville to Panama City

Your Jacksonville to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Jacksonville to Panama?

    Fares from Jacksonville to Panama are around their usual level right now. A round-trip under $493 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.

  • How much should I budget for a flight from Jacksonville to Panama?

    Over the past 12 months, round-trip fares from Jacksonville to Panama have ranged from $493 to $737.

  • What airlines fly nonstop from Jacksonville to Panama?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Jacksonville to Panama. One-stop options include American Airlines and Delta.

  • Which cabin classes are available on flights from Jacksonville to Panama?

    On flights from Jacksonville to Panama you can only book Economy Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

Your guide to booking Jacksonville to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your travel dates are flexible, book your trip for April when flights are typically cheapest and avoid February when prices are at their highest.
  • Flying on Saturday is usually the cheapest. Flights on Friday cost about 20% more on average, so being flexible with your travel dates could help you save.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.

Reviews of the top 3 airlines serving from Jacksonville to Panama

 
Need help choosing which airline to fly with from Jacksonville to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8692 reviews
8.1Boarding
8.5Crew
7.8Comfort
7.2Food
7.8Entertainment
Airline reviews

Delta always provides stellar service. I am always impressed and will try my best to travel via Delta if I can afford it.

10.0 ExcellentCharlean, Oct 2026
Read more Delta reviews

Delta always provides stellar service. I am always impressed and will try my best to travel via Delta if I can afford it.

I think in the future I cannot fly anything less than Comfort plus. The seats vary depending on the plane. The people are extremely nice and funny. I try to only fly Delta if I can help it.

Great flight. Thank you for the upgrade to first class.

Aside from a completely packed plane, I really have no complaints.

The flight was very good and the staff was very friendly and helpful!

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The food is terrible. The staff is wonderful. Comfort is good.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

Flight was on time, the staff was personable & professional, & the plane arrived on time.

Fantastic experience once again flying with United! There was great communication from the cockpit and one of the flight attendants went out of her way to get my two little kids some special treats which elevated our travel experience coming home.

Flight attendants need to know their plane. Seated in first row yesterday. The seat had about a 1 inch recline that was not adjustable. I don't appreciate being awakened to raise a seat that can't go any further forward and such a small recline is either irrelevant or the plane needs to be repaired. Not the way to treat any customer and especially the ones who have paid that level of money for the seats.

Flights was great, service and transit support was outstanding - but the food was limited and of poor quality - only a snack on the first hour for 2 hours 1/2 leg. and a light breakfast on the second 4 hour leg.

typical but they have finally enhanced the wifi on some UA flights. Boy, its such a huge improvement

Wonderful flight! The crew was good, check-in was good and orderly and the flight was uneventful and good.

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

Flight was delayed in the gate by 5 hours and ultimately cancelled- rebooking service by United agents was terrible

United domestic flight was better than international flight. There was no switch to control Ac In international united flight. Food was also average, Air canada food was much better than united.

They cancelled our flight at the last minute due to mechanical issues. Rather, they “delayed” it till the next morning. A pain in the neck when traveling with two young children. Crew was really nice, which made up for it somewhat. This is the second flight from delta that was cancelled this year. Definitely going to fly another airline when possible

Noticing spectacular about the flight. It got me fro m point a to b. High priced

Seats were very tight for a 17 hour flight. Baby cried for 15 out of 17 hours.

Good flight, excellent personnel; poor comfort, small seats, big cost.

Flight was delayed 5 hours only to be cancelled at 1:30am. I did not get on the rescheduled flight because of worry it would be delayed (which it was). I needed to drive home. Horrible.

Flight was delayed due to maintenance issue. Missed my connecting flight. Got rebooked in a middle seat when I had a first class ticket.

Awful. Original flight was delayed 5 hours. Had to to take a connecting flight instead of direct. Had a 4 hour layover. I missed all of my morning meetings getting in 5 hours later than I was supposed to and had to change to take a later flight the next day to get them back in which cia time another $150.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

Delayed 4 hours from Charlotte to Nashville. Could have driven there faster. Information provided by AA was sparse.

Gate change was a little tough but it was a good flight otherwise

Great flight, great service but most of all- our luggage made the trip with us.,

More options for your flight from Jacksonville to Panama

Complete your trip to Panama with a hotel stay or car rental