$80 Find Cheap Flights from Jacksonville to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to South Carolina departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Jacksonville to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Jacksonville to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Jacksonville to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$281
Greenville
Greenville1 stop$271
Columbia
Columbia1 stop$347
Charlotte
Charlotte1 stop$180
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$281
Greenville
Greenville1 stop$271
Columbia
Columbia1 stop$347
Charlotte
Charlotte1 stop$180

Book Cheap Jacksonville to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to South Carolina

Fri, May 1 - Sun, May 3
Frontier Logo
3:27 pm - 10:27 pm
JAX
-
CLT
7h 00m
1 stop
Frontier Logo
6:00 am - 1:29 pm
CLT
-
JAX
7h 29m
1 stop
$180Frontier
Fri, May 8 - Sun, May 10
Frontier Logo
3:27 pm - 10:52 pm
JAX
-
CLT
7h 25m
1 stop
Frontier Logo
6:30 am - 2:32 pm
CLT
-
JAX
8h 02m
1 stop
$181Frontier
Tue, Apr 7 - Tue, Apr 14
Breeze Airways Logo
11:37 am - 10:06 pm
JAX
-
CHS
10h 29m
1 stop
Breeze Airways Logo
7:00 am - 5:08 pm
CHS
-
JAX
10h 08m
1 stop
$249Breeze Airways
Fri, Apr 17 - Wed, Apr 22
Multiple Airlines Logo
12:51 pm - 9:37 pm
JAX
-
CLT
8h 46m
1 stop
Multiple Airlines Logo
9:54 pm - 6:35 pm
CLT
-
JAX
20h 41m
2 stops
$263Multiple Airlines
Fri, Apr 17 - Mon, Apr 20
Multiple Airlines Logo
12:51 pm - 9:37 pm
JAX
-
CLT
8h 46m
1 stop
Multiple Airlines Logo
6:40 am - 8:54 pm
CLT
-
JAX
14h 14m
1 stop
$275Multiple Airlines
Mon, May 4 - Wed, May 6
American Airlines Logo
7:44 pm - 11:59 pm
JAX
-
GSP
4h 15m
1 stop
American Airlines Logo
6:45 pm - 11:59 pm
GSP
-
JAX
5h 14m
1 stop
$281American Airlines
Tue, May 12 - Tue, May 19
Breeze Airways Logo
4:13 pm - 2:59 pm
JAX
-
MYR
22h 46m
1 stop
Breeze Airways Logo
10:38 am - 3:28 pm
MYR
-
JAX
4h 50m
1 stop
$281Breeze Airways
Sat, Apr 4 - Mon, Apr 6
American Airlines Logo
3:55 pm - 9:56 pm
JAX
-
GSP
6h 01m
1 stop
American Airlines Logo
5:00 am - 8:51 am
GSP
-
JAX
3h 51m
1 stop
$291American Airlines
Wed, Apr 22 - Sat, Apr 25
Delta Logo
6:30 am - 9:40 am
JAX
-
MYR
3h 10m
1 stop
Delta Logo
6:11 pm - 10:50 pm
MYR
-
JAX
4h 39m
1 stop
$295Delta
Wed, Apr 8 - Wed, Apr 15
Delta Logo
6:30 am - 9:57 am
JAX
-
CHS
3h 27m
1 stop
Delta Logo
5:20 am - 10:14 am
CHS
-
JAX
4h 54m
1 stop
$319Delta
Booking Insights

KAYAK's insights & trends for Jacksonville to South Carolina flights

Get data-powered insights and trends into flights from Jacksonville to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Jacksonville to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Jacksonville to South Carolina were found on Southwest ($281) and American Airlines ($281).

Good to know

Low seasonDecember
Cheapest flight$80
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 18% lower on average.
Flight from Jacksonville to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Jacksonville to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Jacksonville to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Jacksonville to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Jacksonville to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Jacksonville to the following destinations at these prices or less: Charlotte $179 one-way - $365 round-trip

Reviews of the top airlines flying from Jacksonville to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Jacksonville to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Jacksonville to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8291 reviews
8.1Boarding
7.8Entertainment
8.5Crew
7.2Food
7.9Comfort
Airline reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

2.0 MediocreSusan, Mar 2026
JAX - ATL
Read more Delta reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

The landing was the worst I’ve experienced with a flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

The flight was great as well as the airline staff

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Flights were constantly delayed. CRW took 50 minutes to get bags

Where do I start!! I was delayed with my flight from Dallas to Tampa. On the way back from Tampa to Dallas the flight was delayed over 4 hours+. I was put on another flight that was also delayed but not as long. Traveling on American Airlines is becoming exhausing.

I didn't end up taking this flight. I got up at 4am for a flight that was supposed to board at 6am - at 5:55am you delayed the flight to 10am. The airport is under construction so I switched to a later flight as I wasn't going to sit in the airport for 4 hours. They said the delay was due to the crew needing rest from a flight coming in late the night before - if that was the case then I think you should have delayed the flight much sooner so that passengers wouldn't get up so early and get to the airport to sit and wait.

The flight attendants and the service is getting worse by the day.

Other than nearly three hour delay for maintenance issues, everything went smooth

why would I bother with this airline and pick seats when I am asked to move for a weight imbalance

Overall good. The pilots and flight attendants are excellent! The equipment was the issue on my First flight as they had to wait for a part to be installed. So the take off was at least 30 minutes later.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Everything you need to know for your flight from Jacksonville to South Carolina

Information on your arrival and departure airports