$47 Find Cheap Flights from Key West to Knoxville - Compare and Save

Only Allegiant Air operates flights between Key West and Knoxville.

Flights from Key West to Knoxville usually depart from Key West (EYW) and arrive at Knoxville McGhee Tyson (TYS).

Here are some options for this route, based on selected ticket types and cabin classes:

• Allegiant Air: a checked bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

Only Economy Class is available on flights from Key West to Knoxville.

On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $144 round-trip, compared to $288 via a layover through Tampa St. Petersburg (PIE).

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$90 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A320-100/200 family is used most often on this route, operated mainly by Allegiant Air. Other aircraft seen on the route include Airbus A319 variants.

One-stop flights from Key West to Knoxville most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 53% of one-stop connections
• Charlotte Douglas (CLT) - 29% of one-stop connections
• Miami (MIA) - 12% of one-stop connections
• Tampa St. Petersburg (PIE) - 6% of one-stop connections

Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 88% on the Key West to Knoxville route. Friday is the cheapest departure day at $132 round-trip on average, while Sunday is the most expensive at $1,060, a difference of $928. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

These are the earliest and latest flight times available from Key West to Knoxville:

• Earliest: departs at 9:14 am and lands at 11:28 am
• Latest: departs at 2:33 pm and lands at 4:47 pm.

The flight takes about 2h 14m.

A nonstop flight from Key West to Knoxville takes 2h 14m, covering 788 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

One-way fares from Key West to Knoxville are currently higher than usual. Average one-way flight prices are about $390, which is 94% above the typical average for this route.

Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 4h 28m, compared with 4h 52m via Charlotte Douglas (CLT) and 5h 01m via Miami (MIA).

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
• Budget
• Alamo
• Thrifty
• Enterprise Rent-A-Car
• Payless

Round-trip flights from Key West to Knoxville range from $145 to $427, with an average of $308 over the past 12 months. Anything below $145 counts as a good deal.