EYW - TYS

$95 Find Cheap Flights from Key West to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Key West to Knoxville departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Key West to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Key West to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$95
Typical prices: $198-$461
Allegiant Air
Fri 1/16Mon 1/19
EYW - TYS • Non-stop
Cheapest one-way
$119
Typical prices: $145-$201
Allegiant Air
Sun 1/4
EYW - TYS • 1 stop
Top airlines
Allegiant Air
Cheapest • from $95 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
3 days a week
There are direct flights from Key West to Knoxville 3 days a week: Mon, Fri, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Start a new search
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We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Key West to Knoxville (EYW-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Key West to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Key West to Knoxville

Fri, Jan 16 - Mon, Jan 19
Allegiant Air Logo
5:41 pm - 7:56 pm
EYW
-
TYS
2h 15mnonstop
Allegiant Air Logo
2:40 pm - 4:51 pm
TYS
-
EYW
2h 11mnonstop
$95Allegiant Air
Fri, Jan 16 - Mon, Jan 19
Multiple Airlines Logo
2:25 pm - 11:09 am
EYW
-
TYS
20h 44m1 stop
Multiple Airlines Logo
2:40 pm - 4:51 pm
TYS
-
EYW
2h 11mnonstop
$165Multiple Airlines
Thu, Jan 29 - Mon, Feb 2
Allegiant Air Logo
3:46 pm - 10:10 am
EYW
-
TYS
18h 24m1 stop
Allegiant Air Logo
2:40 pm - 4:51 pm
TYS
-
EYW
2h 11mnonstop
$203Allegiant Air
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
7:45 pm - 11:59 pm
EYW
-
TYS
4h 14m1 stop
American Airlines Logo
4:00 pm - 9:47 pm
TYS
-
EYW
5h 47m1 stop
$231American Airlines
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
1:22 pm - 6:46 pm
EYW
-
TYS
5h 24m1 stop
American Airlines Logo
4:00 pm - 11:56 pm
TYS
-
EYW
7h 56m2 stops
$236American Airlines
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
6:06 am - 3:20 pm
EYW
-
TYS
9h 14m2 stops
American Airlines Logo
4:00 pm - 11:56 pm
TYS
-
EYW
7h 56m2 stops
$241American Airlines
Sat, Jan 3 - Mon, Jan 5
Allegiant Air Logo
10:35 pm - 9:24 pm
EYW
-
TYS
22h 49m1 stop
Allegiant Air Logo
12:58 pm - 9:11 pm
TYS
-
EYW
8h 13m1 stop
$259Allegiant Air
Sat, Jan 24 - Thu, Jan 29
American Airlines Logo
4:37 pm - 11:59 pm
EYW
-
TYS
7h 22m1 stop
American Airlines Logo
4:00 pm - 9:47 pm
TYS
-
EYW
5h 47m1 stop
$269American Airlines
Sat, Jan 24 - Thu, Jan 29
American Airlines Logo
7:26 pm - 11:59 pm
EYW
-
TYS
4h 33m1 stop
American Airlines Logo
2:57 pm - 11:56 pm
TYS
-
EYW
8h 59m2 stops
$274American Airlines
Sat, Jan 24 - Thu, Jan 29
American Airlines Logo
6:06 am - 1:54 pm
EYW
-
TYS
7h 48m2 stops
American Airlines Logo
4:00 pm - 11:56 pm
TYS
-
EYW
7h 56m2 stops
$279American Airlines
Booking Insights

KAYAK's insights & trends for Key West to Knoxville flights

Get data-powered insights and trends into flights from Key West to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Key West to Knoxville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Key West to Knoxville departing in January.

What’s the cheapest day of the week to fly from Key West to Knoxville?

The average price of all round-trip flights from Key West to Knoxville clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Knoxville on a Friday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Key West to Knoxville. For your return ticket, we recommend flying on a Wednesday and avoiding Tuesdays for the best deals.

Can I save money by flying with a layover from Key West to Knoxville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $603 on average.

Good to know

Low seasonOctober
Cheapest flight$95
Best time to beat the crowds with an average 49% drop in price.
Most popular time to fly with an average 58% increase in price.
Flight from Key West to Knoxville

When to book flights from Key West to Knoxville

Are your dates flexible? Find out the best times to travel from Key West to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Key West to Knoxville

  • What is the cheapest flight from Key West to Knoxville?

    In the last 3 days, the lowest price for a flight from Key West to Knoxville was $119 for a one-way ticket and $95 for a round-trip.

  • Do I need a passport to fly between Key West and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Key West to Knoxville?

    When flying out of Key West you will be using Key West. You will be landing at Knoxville, also known as Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Key West to Knoxville?

    The Airbus A319 is the aircraft model that flies most regularly on the Key West to Knoxville flight route.

  • Which airline alliances offer flights from Key West to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Key West and Knoxville, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Key West to Knoxville?

    You can catch a nonstop flight from Key West to Knoxville on on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Key West to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Key West to Knoxville are Delta and American Airlines. With an average price for the route of $498 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $398 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Key West to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Key West to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Key West to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Key West is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Key West to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Key West with another airline. Booking your flights between Key West and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Key West to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Key West up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Key West to Knoxville

  • Looking for a cheap flight? 25% of our users found flights on this route for $45 or less one-way.

Prefer to fly direct from Key West to Knoxville?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Key West to Knoxville McGhee Tyson.
Find which airlines fly direct from Key West Airport to Knoxville McGhee Tyson Airport, which days they fly and book direct flights.

Direct departures

Key West to Knoxville McGhee Tyson

Monday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Knoxville McGhee Tyson to Key West

Monday

Allegiant Air

Allegiant Air

Friday

Allegiant Air

Allegiant Air

Sunday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top airlines flying from Key West to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Key West to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Key West to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8008 reviews
7.9Entertainment
8.5Crew
7.3Food
7.9Comfort
8.1Boarding
Airline reviews

The food is terrible. The staff is wonderful. Comfort is good.

10.0 ExcellentRonda, Dec 2025
JAX - JFK
Read more Delta reviews

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

I appreciated that it was on time, safe and professional. I didn’t like that I wasn’t in a place where I had a window at my window seat. It would have been nice to know that in advance. If it was mentioned in the ticketing, I didn’t notice it.

I like that the crew kept us informed but we moved back and forth from gate to gate before the aircraft arrived.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so didn't have any food

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

We had 3 flights. 1 & 2 were on the same plane but we had to de-board just to re-board 30 mins later. That may have been due to a crew change though. Our 3rd flight had a couple “maintenance” issues that held us up. They were quickly resolved but it took forever for someone to bring the paperwork needed so we could leave. Apparently there was a computer glitch so a driver had to bring a physical copy. It delayed us about 1 1/2 hrs. The flights themselves were smooth & no problems. For boarding, I don’t know why they don’t start with the back of the plane & move forward. It would eliminate the back up from people trying to find their seats & put their bags in the overhead bins. Unless you’re on an overseas flight, there is no food, you get a beverage & either a small bag of pretzels or a biscuit cookie. Take your own food or snacks of you want something more.

Lost bag and 2 days no word leaving for cruise no clothes or stuff

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Food was ok, but not as good as I have had before on AA.

Everything you need to know for your flight from Key West to Knoxville

Information on your arrival and departure airports