EYW - ECP

$298 Find Cheap Flights from Key West to Panama City - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$927
Typical prices: $353-$736
United Airlines
Mon 12/17Fri 12/21
EYW - ECP • 1 stop
Cheapest one-way
$298
Typical prices: $311-$367
Delta
Fri 12/14
EYW - ECP • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Key West and Panama City. You'll need to take a connecting flight to reach the destination.
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Top layover airports
Charlotte Douglas (CLT)
Cheapest • Avg $539 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 4h 50m (one-way)
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Cheap Flights from Key West to Panama City (EYW-ECP)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Key West to Panama City

Thu, Dec 17 - Mon, Dec 21
United Airlines Logo
12:22 pm - 4:45 pmEYW  Key West-ECP Panama City NW Florida Beaches
29h 23m1 stop Chicago O'Hare Intl
United Airlines Logo
2:00 pm - 12:07 pmECP  Panama City NW Florida Beaches-EYW Key West
21h 07m3 stops Chicago O'Hare Intl Cleveland Hopkins Intl Washington, D.C. Dulles Intl
$927United Airlines
Thu, Dec 17 - Mon, Dec 21
United Airlines Logo
1:35 pm - 4:45 pmEYW  Key West-ECP Panama City NW Florida Beaches
28h 10m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
2:00 pm - 12:07 pmECP  Panama City NW Florida Beaches-EYW Key West
21h 07m3 stops Chicago O'Hare Intl Cleveland Hopkins Intl Washington, D.C. Dulles Intl
$933United Airlines
Thu, Dec 17 - Mon, Dec 21
United Airlines Logo
5:52 pm - 4:45 pmEYW  Key West-ECP Panama City NW Florida Beaches
23h 53m1 stop Chicago O'Hare Intl
United Airlines Logo
5:28 pm - 5:11 pmECP  Panama City NW Florida Beaches-EYW Key West
22h 43m1 stop Chicago O'Hare Intl
$937United Airlines
Thu, Dec 17 - Mon, Dec 21
United Airlines Logo
1:35 pm - 1:17 pmEYW  Key West-ECP Panama City NW Florida Beaches
24h 42m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
2:00 pm - 11:41 amECP  Panama City NW Florida Beaches-EYW Key West
20h 41m1 stop Chicago O'Hare Intl
$942United Airlines
Thu, Dec 17 - Mon, Dec 21
United Airlines Logo
4:04 pm - 2:11 pmEYW  Key West-ECP Panama City NW Florida Beaches
23h 07m3 stops Chicago O'Hare Intl Louisville Intl Houston George Bush Intcntl
United Airlines Logo
2:00 pm - 12:07 pmECP  Panama City NW Florida Beaches-EYW Key West
21h 07m3 stops Chicago O'Hare Intl Cleveland Hopkins Intl Washington, D.C. Dulles Intl
$972United Airlines
Booking Insights

Price, demand and travel trends for Key West to Panama City flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Key West to Panama City?

Round-trip flights from Key West to Panama City typically range from $353 to $736. The lowest price found in the past 5 days was $927, on United Airlines.

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Key details for Key West to Panama City flights

Cheapest flight

$298
One-way flight from Key West to Panama City

When to book flights from Key West to Panama City

Are your dates flexible? Find out the best times to travel from Key West to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Key West to Panama City flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Key West to Panama City?

    Only Economy Class is available on flights from Key West to Panama City.

  • How long is a flight from Key West to Panama City?

    A nonstop flight from Key West to Panama City takes 00m, covering 471 miles.

  • Do I need a passport to fly from Key West to Panama City?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • Have flight prices from Key West to Panama City changed much recently?

    Based on fares seen in the past 5 days, round-trip prices on this route were fairly steady, ranging from about $927 to $972. The highest observed fare was only about 4% higher than the lowest one.

  • How are flight prices from Key West to Panama City looking right now?

    One-way fares from Key West to Panama City are currently lower than usual. Average one-way flight prices are about $298, which is 19% below the typical average for this route.

  • What car rental options are available at Panama City NW Florida Beaches Airport (ECP)?

    Panama City NW Florida Beaches Airport (ECP) hosts 5 major car rental companies, with daily rates averaging $67 for economy cars. Top options include:

    • Dollar
    • Hertz
    • Budget
    • Alamo
    • Avis

  • Which airports can I use when flying from Key West to Panama City?

    Flights from Key West to Panama City usually depart from Key West (EYW) and arrive at Panama City NW Florida Beaches (ECP).

  • Which airports do connecting flights from Key West to Panama City pass through?

    Connecting flights from Key West to Panama City most commonly pass through:

    • Atlanta Hartsfield-Jackson (ATL) - 64% of one-stop connections
    • Charlotte Douglas (CLT) - 36% of one-stop connections

  • Can I save money by using flexible dates for flights from Key West to Panama City?

    Yes. Flexible dates can save you up to 53% on flights from Key West to Panama City. Wednesday is the cheapest departure day at $353 round-trip on average, while Monday is the most expensive at $736, a difference of $383.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Key West to Panama City?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 4h 50m, compared with 5h 51m via Charlotte Douglas (CLT).

  • What is the time difference between Key West and Panama City?

    Panama City is 1 hour behind Key West (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Key West to Panama City flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $353, about $383 less than Monday fares (52% savings) based on the last 12 months.
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City NW Florida Beaches Airport.

    • Hilton Garden Inn Panama City Airport

More options for your flight from Key West to Panama City

Complete your trip to Panama City with a hotel stay or car rental

Car rentals in Panama City
Hotels in Panama City