ECP - EYW

$393 Find Cheap Flights from Panama City to Key West - Compare and Save

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Everything you should know

Cheapest round-trip
$397
Typical prices: $346-$577
Delta
Tue 1/23Mon 1/29
ECP - EYW • 1 stop
Cheapest one-way
$393
Typical prices: $272-$368
Delta
Wed 11/28
ECP - EYW • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Panama City and Key West. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 26% price drop
January
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Charlotte Douglas (CLT)
Cheapest • Avg $328 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 4h 43m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Panama City to Key West (ECP-EYW)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Key West

Sat, Jan 23 - Fri, Jan 29
Delta Logo
6:00 am - 10:58 amECP  Panama City NW Florida Beaches-EYW Key West
3h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:35 pm - 7:36 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 01m1 stop Atlanta Hartsfield-Jackson
$397Delta
Thu, Jan 21 - Fri, Jan 29
Delta Logo
6:00 am - 10:58 amECP  Panama City NW Florida Beaches-EYW Key West
3h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:35 pm - 7:36 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 01m1 stop Atlanta Hartsfield-Jackson
$397Delta
Fri, Jan 22 - Fri, Jan 29
Delta Logo
12:00 pm - 7:43 pmECP  Panama City NW Florida Beaches-EYW Key West
6h 43m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:35 pm - 7:36 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 01m1 stop Atlanta Hartsfield-Jackson
$397Delta
Mon, Nov 30 - Sat, Dec 5
Delta Logo
9:30 am - 5:10 pmECP  Panama City NW Florida Beaches-EYW Key West
6h 40m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 11:17 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 11m1 stop Atlanta Hartsfield-Jackson
$417Delta
Fri, Nov 20 - Wed, Nov 25
Delta Logo
6:00 am - 10:48 amECP  Panama City NW Florida Beaches-EYW Key West
3h 48m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:08 pm - 11:24 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 16m1 stop Atlanta Hartsfield-Jackson
$447Delta
Tue, Dec 1 - Sat, Dec 5
Delta Logo
1:38 pm - 8:01 pmECP  Panama City NW Florida Beaches-EYW Key West
5h 23m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 11:17 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 11m1 stop Atlanta Hartsfield-Jackson
$468Delta
Sat, Jan 23 - Sat, Jan 30
Delta Logo
6:00 am - 10:58 amECP  Panama City NW Florida Beaches-EYW Key West
3h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 10:47 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 47m1 stop Atlanta Hartsfield-Jackson
$468Delta
Fri, Jan 22 - Sat, Jan 30
Delta Logo
12:00 pm - 7:43 pmECP  Panama City NW Florida Beaches-EYW Key West
6h 43m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 10:47 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 47m1 stop Atlanta Hartsfield-Jackson
$468Delta
Fri, Jan 22 - Sat, Jan 30
American Airlines Logo
12:02 pm - 5:54 pmECP  Panama City NW Florida Beaches-EYW Key West
4h 52m1 stop Charlotte Douglas
American Airlines Logo
9:58 am - 5:17 pmEYW  Key West-ECP Panama City NW Florida Beaches
8h 19m2 stops Miami Charlotte Douglas
$580American Airlines
Thu, Feb 4 - Sun, Feb 7
American Airlines Logo
1:12 pm - 6:08 pmECP  Panama City NW Florida Beaches-EYW Key West
27h 56m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:48 pm - 12:41 pmEYW  Key West-ECP Panama City NW Florida Beaches
18h 53m1 stop Washington, D.C. Reagan-National
$595American Airlines
Booking Insights

Price, demand and travel trends for Panama City to Key West flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Panama City to Key West?

Round-trip flights from Panama City to Key West typically range from $346 to $577. The lowest price found in the past 5 days was $397, on Delta.

What's the cheapest day of the week to fly from Panama City to Key West?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Panama City to Key West. It’s 18% cheaper than the average day, while Sunday is the most expensive, with prices 85% higher.

What’s the cheapest month to fly from Panama City to Key West?

•February is the cheapest month to fly from Panama City to Key West at $332 round-trip.
•September ($678) and March ($671) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 104% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

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Key details for Panama City to Key West flights

Low season

June

Cheapest flight

$393
Beat the crowds with an average 52% drop in travelers.
The most popular month to fly with an average 52% increase in travelers.
One-way flight from Panama City to Key West

When to book flights from Panama City to Key West

Are your dates flexible? Find out the best times to travel from Panama City to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Key West flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Panama City to Key West?

    Two cabin classes are available on flights from Panama City to Key West:

    • Economy Class
    • First Class

  • How long is a flight from Panama City to Key West?

    A nonstop flight from Panama City to Key West takes 00m, covering 471 miles.

  • Do I need a passport to fly from Panama City to Key West?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Panama City to Key West flight?

    Round-trip flights from Panama City to Key West range from $346 to $577, with an average of $446 over the past 12 months. Anything below $346 counts as a good deal.

  • Have flight prices from Panama City to Key West changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $397 to $1,153. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Panama City to Key West looking right now?

    One-way fares from Panama City to Key West are currently higher than usual. Average one-way flight prices are about $435, which is 23% above the typical average for this route.

  • What car rental options are available at Key West Airport (EYW)?

    Key West Airport (EYW) hosts 5 major car rental companies, with daily rates starting from around $29 for economy cars. Top options include:

    • Dollar
    • Hertz
    • Budget
    • Enterprise Rent-A-Car
    • Alamo

  • Which airports can I use when flying from Panama City to Key West?

    Flights from Panama City to Key West usually depart from Panama City NW Florida Beaches (ECP) and arrive at Key West (EYW).

  • Which airports do connecting flights from Panama City to Key West pass through?

    Connecting flights from Panama City to Key West most commonly pass through:

    • Atlanta Hartsfield-Jackson (ATL) - 97% of one-stop connections
    • Charlotte Douglas (CLT) - 3% of one-stop connections

  • Can I save money by using flexible dates for flights from Panama City to Key West?

    Yes. Flexible dates can save you up to 56% on flights from Panama City to Key West. Friday is the cheapest departure day at $366 round-trip on average, while Sunday is the most expensive at $827, a difference of $461.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Panama City to Key West?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 4h 43m, compared with 5h 11m via Charlotte Douglas (CLT).

  • What is the time difference between Panama City and Key West?

    Key West is 1 hour ahead of Panama City (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Key West?

    Some of the most popular sights in Key West are Duval Street, Key West Historic District and Mallory Square. These are among the most viewed places in Key West on KAYAK.

Your guide to booking Panama City to Key West flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Sunday. On this route, Friday flights average $366, about $461 less than Sunday fares (56% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to Key West trip for February. Fares historically average $332 round-trip in that month - typically $346 less than the most expensive month, which is September (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Key West Airport.

    • Parrot Key Hotel & Villas
    • Havana Cabana at Key West
    • Fairfield Inn & Suites by Marriott Key West at The Keys Collection

More options for your flight from Panama City to Key West

Complete your trip to Key West with a hotel stay or car rental

Car rentals in Key West
Hotels in Key West
Vacations in Key West