ECP - EYW

$273 Find Cheap Flights from Panama City to Key West - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$367
Typical prices: $340-$552
Delta
Fri 9/28Sat 10/6
ECP - EYW • 1 stop
Cheapest one-way
$273
Typical prices: $288-$368
Delta
Sun 9/30
ECP - EYW • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Panama City and Key West. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 25% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Miami (MIA)
Cheapest • Avg $294 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 4h 48m (one-way)
Insights
Insights
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We hope you love your trip to Key West!
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Flight Deals

Cheap Flights from Panama City to Key West (ECP-EYW)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Key West

Mon, Sep 28 - Tue, Oct 6
Delta Logo
9:23 am - 5:23 pmECP  Panama City NW Florida Beaches-EYW Key West
7h 00m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 pm - 11:18 pmEYW  Key West-ECP Panama City NW Florida Beaches
6h 08m1 stop Atlanta Hartsfield-Jackson
$367Delta
Tue, Jan 26 - Sat, Jan 30
American Airlines Logo
12:03 pm - 6:01 pmECP  Panama City NW Florida Beaches-EYW Key West
4h 58m1 stop Charlotte Douglas
American Airlines Logo
7:08 am - 11:33 amEYW  Key West-ECP Panama City NW Florida Beaches
5h 25m1 stop Charlotte Douglas
$367American Airlines
Wed, Jan 6 - Sat, Jan 9
American Airlines Logo
12:03 pm - 6:01 pmECP  Panama City NW Florida Beaches-EYW Key West
4h 58m1 stop Charlotte Douglas
American Airlines Logo
1:22 pm - 5:33 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 11m1 stop Charlotte Douglas
$367American Airlines
Mon, Oct 26 - Mon, Nov 2
American Airlines Logo
7:15 am - 4:11 pmECP  Panama City NW Florida Beaches-EYW Key West
7h 56m1 stop Charlotte Douglas
American Airlines Logo
6:26 pm - 10:52 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 26m1 stop Charlotte Douglas
$377American Airlines
Fri, Sep 11 - Fri, Sep 18
Delta Logo
1:46 pm - 8:00 pmECP  Panama City NW Florida Beaches-EYW Key West
5h 14m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 9:03 pmEYW  Key West-ECP Panama City NW Florida Beaches
3h 44m1 stop Atlanta Hartsfield-Jackson
$397Delta
Fri, Sep 11 - Fri, Sep 18
Delta Logo
1:46 pm - 8:00 pmECP  Panama City NW Florida Beaches-EYW Key West
5h 14m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 9:03 pmEYW  Key West-ECP Panama City NW Florida Beaches
3h 44m1 stop Atlanta Hartsfield-Jackson
$427Delta
Wed, Sep 9 - Wed, Sep 16
Delta Logo
6:00 am - 10:46 amECP  Panama City NW Florida Beaches-EYW Key West
3h 46m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 11:05 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 46m1 stop Atlanta Hartsfield-Jackson
$427Delta
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
7:15 am - 4:11 pmECP  Panama City NW Florida Beaches-EYW Key West
7h 56m1 stop Charlotte Douglas
American Airlines Logo
7:19 pm - 11:53 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 34m1 stop Charlotte Douglas
$453American Airlines
Thu, Oct 29 - Mon, Nov 2
American Airlines Logo
7:15 am - 4:11 pmECP  Panama City NW Florida Beaches-EYW Key West
7h 56m1 stop Charlotte Douglas
American Airlines Logo
6:26 pm - 10:52 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 26m1 stop Charlotte Douglas
$453American Airlines
Thu, Oct 29 - Sun, Nov 1
American Airlines Logo
7:15 am - 4:11 pmECP  Panama City NW Florida Beaches-EYW Key West
7h 56m1 stop Charlotte Douglas
American Airlines Logo
7:18 pm - 11:48 pmEYW  Key West-ECP Panama City NW Florida Beaches
5h 30m1 stop Charlotte Douglas
$453American Airlines
Booking Insights

Price, demand and travel trends for Panama City to Key West flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Panama City to Key West with more confidence.

How much is a round-trip flight from Panama City to Key West?

Round-trip flights from Panama City to Key West start at $367. Prices are typical for this route right now, with typical round-trip fares ranging from $340 to $552. The lowest price found in the past 5 days was $367 on Delta.

What's the cheapest day of the week to fly from Panama City to Key West?

Thursday is the cheapest day of the week to fly from Panama City to Key West, it is 25% cheaper than the average day. Saturday is the most expensive day with flight prices 51% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Panama City to Key West?

  • February is the cheapest month to fly from Panama City to Key West at $332 round-trip.
  • March ($671) and September ($552) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 102% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Panama City to Key West flights

Low season

June

Cheapest flight

$273
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Panama City to Key West

When to book flights from Panama City to Key West

Are your dates flexible? Find out the best times to travel from Panama City to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to Key West flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Panama City to Key West?

    Flights from Panama City to Key West usually depart from Panama City NW Florida Beaches (ECP) and arrive at Key West (EYW).

  • What cabin classes can I book on flights from Panama City to Key West?

    Two cabin classes are available on flights from Panama City to Key West:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Panama City to Key West pass through?

    One-stop flights from Panama City to Key West most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 93% of one-stop connections
    • Charlotte Douglas (CLT) - 5% of one-stop connections
    • Miami (MIA) - 2% of one-stop connections

    Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Panama City to Key West?

    Yes. Being flexible with your travel dates can save you up to 51% on the Panama City to Key West route. Thursday is the cheapest departure day at $332 round-trip on average, while Saturday is the most expensive at $671, a difference of $339. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Key West?

    Some of the most popular sights in Key West are Duval Street, Key West Historic District and Mallory Square. These are among the most viewed places in Key West on KAYAK.

  • How long is a flight from Panama City to Key West?

    A nonstop flight from Panama City to Key West takes 0h 00m, covering 471 miles.

  • Do I need a passport to fly from Panama City to Key West?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Panama City to Key West changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $367 to $1,094. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Panama City to Key West looking right now?

    One-way fares from Panama City to Key West are currently higher than usual. Average one-way flight prices are about $421, which is 19% above the typical average for this route.

  • How much time can I save by choosing a different layover airport from Panama City to Key West?

    Flying via Miami (MIA) gives the shortest average 1-stop total travel time at 4h 16m, compared with 4h 48m via Atlanta Hartsfield-Jackson (ATL) and 5h 34m via Charlotte Douglas (CLT).

  • What is the time difference between Panama City and Key West?

    Key West is 1 hour ahead of Panama City (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Key West Airport (EYW)?

    Key West Airport (EYW) hosts 5 major car rental companies, with daily rates starting from around $29 for economy cars. Top options include:
    · Dollar
    · Hertz
    · Budget
    · Enterprise Rent-A-Car
    · Alamo

  • How much should I expect to pay for a Panama City to Key West flight?

    Round-trip flights from Panama City to Key West range from $340 to $552, with an average of $442 over the past 12 months. Anything below $340 counts as a good deal.

Your guide to booking Panama City to Key West flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Saturday. On this route, Thursday flights average $332 - about $339 less than Saturday (51% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to Key West trip for February. Fares historically average $332 round-trip in that month - typically $339 less than the most expensive month, which is March (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Key West Airport.
    - Havana Cabana at Key West
    - Fairfield Inn & Suites by Marriott Key West at The Keys Collection
    - Parrot Key Hotel & Villas

Everything you need to know for your flight from Panama City to Key West

Information on your arrival and departure airports

Panama City (ECP)
Key West (EYW)