ECP - EYW

$268 Find Cheap Flights from Panama City to Key West

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Key West departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Key West

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Key West, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Key West, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$327
Overall average: $665
American Airlines
Wed 3/18Wed 3/25
ECP - EYW • 1 stop
Cheapest one-way
$268
Delta
Wed 3/11
ECP - EYW • 1 stop
Top airlines
American Airlines
Cheapest • from $327 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
October
Cheapest • 34% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Key West!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Key West (ECP-EYW)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Key West that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Key West

Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
4:34 pm - 10:37 pm
ECP
-
EYW
5h 03m
1 stop
American Airlines Logo
4:40 pm - 11:49 pm
EYW
-
ECP
8h 09m
1 stop
$327American Airlines
Thu, Mar 19 - Wed, Mar 25
Delta Logo
6:00 am - 10:48 am
ECP
-
EYW
3h 48m
1 stop
Delta Logo
6:25 pm - 11:04 pm
EYW
-
ECP
5h 39m
1 stop
$357Delta
Thu, Jul 2 - Thu, Jul 9
Delta Logo
6:00 am - 12:23 pm
ECP
-
EYW
5h 23m
1 stop
Delta Logo
2:35 pm - 7:36 pm
EYW
-
ECP
6h 01m
1 stop
$367Delta
Mon, Mar 16 - Tue, Mar 24
American Airlines Logo
4:34 pm - 10:37 pm
ECP
-
EYW
5h 03m
1 stop
American Airlines Logo
8:04 am - 1:30 pm
EYW
-
ECP
6h 26m
1 stop
$387American Airlines
Fri, May 29 - Mon, Jun 1
Delta Logo
2:50 pm - 7:49 pm
ECP
-
EYW
3h 59m
1 stop
Delta Logo
7:30 am - 10:44 am
EYW
-
ECP
4h 14m
1 stop
$403Delta
Thu, Mar 5 - Mon, Mar 9
Delta Logo
9:26 am - 5:01 pm
ECP
-
EYW
6h 35m
1 stop
Delta Logo
6:25 pm - 11:04 pm
EYW
-
ECP
5h 39m
1 stop
$407Delta
Mon, Mar 16 - Sat, Mar 28
Delta Logo
6:00 am - 10:48 am
ECP
-
EYW
3h 48m
1 stop
Delta Logo
6:25 pm - 8:40 am
EYW
-
ECP
15h 15m
1 stop
$427Delta
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
7:19 am - 7:12 pm
ECP
-
EYW
10h 53m
2 stops
American Airlines Logo
4:40 pm - 11:49 pm
EYW
-
ECP
8h 09m
1 stop
$429American Airlines
Mon, Mar 16 - Wed, Mar 25
American Airlines Logo
4:34 pm - 10:37 pm
ECP
-
EYW
5h 03m
1 stop
American Airlines Logo
3:56 pm - 11:49 pm
EYW
-
ECP
8h 53m
2 stops
$449American Airlines
Sat, Mar 21 - Wed, Mar 25
Delta Logo
7:05 am - 10:48 am
ECP
-
EYW
26h 43m
1 stop
Delta Logo
6:25 pm - 11:04 pm
EYW
-
ECP
5h 39m
1 stop
$456Delta
Booking Insights

KAYAK's insights & trends for Panama City to Key West flights

Get data-powered insights and trends into flights from Panama City to Key West to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to Key West?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Key West, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Key West is October, where tickets cost $306 (return) on average. On the other hand, the most expensive months are March and April, where the average cost of round-trip tickets is $665 and $654 respectively.

Good to know

Low seasonOctober
Cheapest flight$268
Best time to beat the crowds with an average 34% drop in price.
Most popular time to fly and prices are also 18% lower on average.
Flight from Panama City to Key West

When to book flights from Panama City to Key West

Are your dates flexible? Find out the best times to travel from Panama City to Key West based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Key West

  • What is the cheapest flight from Panama City to Key West?

    In the last 3 days, the lowest price for a flight from Panama City to Key West was $268 for a one-way ticket and $327 for a round-trip.

  • Do I need a passport to fly between Panama City and Key West?

    No

  • Which aircraft models fly most regularly from Panama City to Key West?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Key West?

    oneworld, and SkyTeam are the airline alliances operating flights between Panama City and Key West, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Key West, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Key West are Delta and American Airlines. With an average price for the route of $491 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $332 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Panama City to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to Panama City with another airline. Booking your flights between Panama City and EYW can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to Key West

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Key West. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Key West? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8212 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

10.0 ExcellentSoosnata, Feb 2026
MIA - LAX
Read more Delta reviews

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Delta is a good airline. I've never had an issue with Delta. I'll continue to fly with them until they show me that I shouldn't.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

The flight was really crowded. Flight attendants were just ok.

Didn't get a seat assignment until the last minute even though i picked a seat.

Flight was on time and the meal and service were good.

Old equipment, needs upgrade and seat comfort. Internet didn't work 75% or the time.

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

On the plus side, crew was attentive, drinks were cold, and in-flight entertainment selection was better than some other airlines. On the negative aide, Plane was delayed almost an hour, either no announcements from the gate crew. Biscoff cookies are gross, appreciate airlines that give a choice. Also, crew had no personality or enthusiasm at all.

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

Everything you need to know for your flight from Panama City to Key West

Information on your arrival and departure airports