$169 Find Cheap Flights from Knoxville to Iowa

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Iowa departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Iowa

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Iowa, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Iowa, as well as popular online travel agencies
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Cheap Flights from Knoxville to Iowa

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Des Moines
Des Moines1 stop$315
Moline
Moline1 stop$321
Des Moines
Des Moines1 stop$315
Moline
Moline1 stop$321

Book Cheap Knoxville to Iowa Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Iowa that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Iowa

Wed, Dec 31 - Sun, Jan 4
American Airlines Logo
8:30 am - 1:21 pm
TYS
-
DSM
5h 51m1 stop
American Airlines Logo
6:26 pm - 11:47 pm
DSM
-
TYS
4h 21m1 stop
$315American Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
6:45 am - 11:46 am
TYS
-
MLI
6h 01m1 stop
United Airlines Logo
8:15 am - 1:20 pm
MLI
-
TYS
4h 05m1 stop
$321United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
11:07 am - 5:36 pm
TYS
-
OMA
7h 29m1 stop
United Airlines Logo
3:21 pm - 8:52 pm
OMA
-
TYS
4h 31m1 stop
$326United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
11:07 am - 2:25 pm
TYS
-
OMA
4h 18m1 stop
United Airlines Logo
8:00 am - 7:27 pm
OMA
-
TYS
10h 27m2 stops
$331United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
9:30 am - 5:36 pm
TYS
-
OMA
9h 06m2 stops
United Airlines Logo
8:00 am - 7:50 pm
OMA
-
TYS
10h 50m2 stops
$336United Airlines
Fri, Apr 17 - Sun, Apr 19
Delta Logo
7:20 pm - 11:55 pm
TYS
-
OMA
5h 35m1 stop
Delta Logo
6:30 pm - 11:46 pm
OMA
-
TYS
4h 16m1 stop
$337Delta
Tue, Dec 30 - Sat, Jan 3
American Airlines Logo
5:23 am - 10:39 am
TYS
-
MLI
6h 16m1 stop
American Airlines Logo
6:00 am - 10:50 am
MLI
-
TYS
3h 50m1 stop
$339American Airlines
Tue, Dec 30 - Sat, Jan 3
Delta Logo
7:05 am - 10:38 am
TYS
-
DSM
4h 33m1 stop
Delta Logo
5:55 pm - 11:13 pm
DSM
-
TYS
4h 18m1 stop
$359Delta
Sun, Dec 28 - Wed, Dec 31
Allegiant Air Logo
12:31 pm - 3:40 pm
TYS
-
DSM
28h 09m2 stops
Allegiant Air Logo
1:45 pm - 9:07 pm
DSM
-
TYS
6h 22m1 stop
$425Allegiant Air
Sun, Dec 28 - Wed, Dec 31
Allegiant Air Logo
10:04 pm - 10:03 am
TYS
-
DSM
12h 59m1 stop
Allegiant Air Logo
1:45 pm - 9:07 pm
DSM
-
TYS
6h 22m1 stop
$463Allegiant Air
Booking Insights

KAYAK's insights & trends for Knoxville to Iowa flights

Get data-powered insights and trends into flights from Knoxville to Iowa to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Knoxville to Iowa?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Iowa, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Iowa is September, when tickets cost $248 (return) on average. On the other hand, the most expensive months are March and October, when the average cost of round-trip tickets is $757 and $421 respectively.

What’s the cheapest day of the week to fly from Knoxville to Iowa?

The average price of all round-trip flights from Knoxville to Iowa clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Knoxville to Iowa, look for departures on Thursdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Iowa, Saturday is the cheapest day to fly and Monday is the most expensive.

Good to know

Low seasonMarch
Cheapest flight$169
Best time to beat the crowds but there is an average 111% increase in price.
Most popular time to fly and prices are also 26% lower on average.
Flight from Knoxville to Omaha

FAQs - booking Iowa flights

  • How does KAYAK find such low prices on flights from Knoxville to Iowa?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Iowa.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Iowa?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Iowa?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Iowa with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Iowa?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Iowa?

    The cheapest time of day to fly to Iowa is generally in the morning, when round-trip flights cost $320 on average. Morning departures are around 4% cheaper than evening flights, on average. The most expensive time of day to fly to Iowa is generally at night, which is peak travel time and where the average cost of a ticket is $338.

Reviews of the top 3 airlines serving from Knoxville to Iowa

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Iowa. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Iowa? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8008 reviews
7.3Food
8.1Boarding
7.9Comfort
7.9Entertainment
8.5Crew
Airline reviews

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

10.0 ExcellentMargaret, Dec 2025
BOS - PIT
Read more Delta reviews

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

United have really come back. Airport and boarding process is clear and good, app and information also very good

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very bad! They kept delaying my flight and wouldn’t do anything about it

They brought an empty plane to the gate. Then a flight delay was announced for maintenance and waiting on a part. I was then put on a flight to San Francisco instead with a connecting flight to my final destination. Arrived at my final destination 2 hours late.

The only downside was my cell phone charger wouldn’t work in the charging port but everyone else’s would work in them all. My cell phone cable works fine in my hotel room in Frankfurt.

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Ot was overall fine. Left on time and had basic snacks. Weather was finicky but that’s not the airlines fault.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

Everything you need to know for your flight from Knoxville to Iowa

Information on your arrival and departure airports