TYS - MYR

$253 Find Cheap Flights from Knoxville to Myrtle Beach

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Myrtle Beach departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Myrtle Beach

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Myrtle Beach, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Myrtle Beach, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$253
Typical prices: $347-$537
Multiple Airlines
Wed 1/28Wed 2/4
TYS - MYR • 1 stop
Cheapest one-way
Multiple Airlines
Thu 12/11
TYS - MYR • multi-stop
Video guide: How to find cheap flights to Myrtle Beach
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When to travel
August
Cheapest • 32% price drop
May
Most popular
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Myrtle Beach (TYS-MYR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Myrtle Beach that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Myrtle Beach

Wed, Jan 28 - Wed, Feb 4
Multiple Airlines Logo
3:53 pm - 11:43 am
TYS
-
MYR
19h 50m1 stop
Multiple Airlines Logo
10:00 am - 6:36 pm
MYR
-
TYS
32h 36m2 stops
$253Multiple Airlines
Wed, Dec 24 - Thu, Jan 1
Multiple Airlines Logo
5:31 pm - 6:08 pm
TYS
-
MYR
24h 37m1 stop
Multiple Airlines Logo
9:54 am - 8:33 am
MYR
-
TYS
22h 39m1 stop
$283Multiple Airlines
Wed, Jan 28 - Wed, Feb 4
Multiple Airlines Logo
4:47 pm - 2:42 pm
TYS
-
MYR
21h 55m3 stops
Multiple Airlines Logo
10:00 am - 8:39 am
MYR
-
TYS
22h 39m2 stops
$294Multiple Airlines
Wed, Jan 28 - Wed, Feb 4
Delta Logo
5:40 am - 9:46 am
TYS
-
MYR
4h 06m1 stop
Delta Logo
6:00 am - 9:24 am
MYR
-
TYS
3h 24m1 stop
$307Delta
Sat, May 23 - Sat, May 30
American Airlines Logo
8:48 pm - 11:27 pm
TYS
-
MYR
2h 39m1 stop
American Airlines Logo
4:22 pm - 7:01 pm
MYR
-
TYS
2h 39m1 stop
$317American Airlines
Wed, Dec 24 - Thu, Jan 1
Multiple Airlines Logo
5:31 pm - 10:05 am
TYS
-
MYR
16h 34m2 stops
Multiple Airlines Logo
9:54 am - 8:33 am
MYR
-
TYS
22h 39m1 stop
$321Multiple Airlines
Tue, Dec 23 - Sun, Dec 28
Multiple Airlines Logo
9:08 am - 6:08 pm
TYS
-
MYR
9h 00m1 stop
Multiple Airlines Logo
7:32 pm - 10:15 am
MYR
-
TYS
14h 43m1 stop
$336Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
4:15 pm - 10:28 pm
TYS
-
MYR
6h 13m1 stop
American Airlines Logo
3:11 pm - 8:05 pm
MYR
-
TYS
4h 54m1 stop
$347American Airlines
Wed, Jan 28 - Wed, Feb 4
Multiple Airlines Logo
4:47 pm - 2:42 pm
TYS
-
MYR
21h 55m3 stops
Multiple Airlines Logo
10:00 am - 8:39 am
MYR
-
TYS
22h 39m3 stops
$352Multiple Airlines
Tue, Dec 30 - Thu, Jan 1
American Airlines Logo
5:00 am - 9:20 am
TYS
-
MYR
4h 20m1 stop
American Airlines Logo
5:11 am - 8:56 am
MYR
-
TYS
3h 45m1 stop
$377American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Myrtle Beach flights

Get data-powered insights and trends into flights from Knoxville to Myrtle Beach to help you find the cheapest flights, the best time to fly and much more.

Find cheap flights to Myrtle Beach
Find cheap flights to Myrtle Beach

Planning a trip from Knoxville to Myrtle Beach? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

How much is a round-trip flight from Knoxville to Myrtle Beach?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Myrtle Beach departing in January.

What’s the cheapest day of the week to fly from Knoxville to Myrtle Beach?

The average price of all round-trip flights from Knoxville to Myrtle Beach clicked on KAYAK for each day over the last 12 months.

For Knoxville to Myrtle Beach, Tuesday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Myrtle Beach back to Knoxville, the best deals are generally found on Tuesday, with Sunday being the most expensive.

What is the cheapest month to fly from Knoxville to Myrtle Beach?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Myrtle Beach, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Myrtle Beach is August, where tickets cost $256 (return) on average. On the other hand, the most expensive months are January and November, where the average cost of round-trip tickets is $583 and $515 respectively.

Good to know

Low seasonJanuary
Cheapest flight$253
Best time to beat the crowds but there is an average 55% increase in price.
Most popular time to fly and prices are also 23% lower on average.
Flight from Knoxville to Myrtle Beach

When to book flights from Knoxville to Myrtle Beach

Are your dates flexible? Find out the best times to travel from Knoxville to Myrtle Beach based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Myrtle Beach

  • Does Knoxville McGhee Tyson Airport allow passengers to travel with animals?

    Yes. TYS allows approved service animals to accompany passengers. Service animals must be on a leash while in the airport. You will find animal relief areas for your furry friend on the West side of the Terminal, near the west surface or economy lot crosswalk.

  • Does Knoxville McGhee Tyson Airport have any amenities for nursing mothers?

    Yes. Traveling nursing mothers departing from TYS can enjoy the privacy of the private Mamava pod located past the security checkpoint opposite the food concession area. The pod is lockable, self-contained, and has a comfortable sitting space, a fold-down table, and an electrical outlet for plugging in a breast pump.

  • What ground transportation options do I have upon arrival at MYR?

    You can choose any of the following six ground transportation options upon arrival; public transportation, taxi cab service, rideshare service, hotel shuttle, limousine service, or car rental service. Taxicab service, available on a first-come, first-serve basis, is located outside Door 6 at Baggage Claim. Public Transport is the most affordable and the nearest bus stop is Jet port road.

  • Does Myrtle Beach International Airport have lounges?

    Yes. You can get access to MYR business lounge. The luxury airport lounge is open to passengers from all classes, and it features a comfortable sitting area, access to snacks and drinks, conference facilities and newspapers and magazines to keep you entertained.

  • What is the cheapest flight from Knoxville to Myrtle Beach?

    In the last 3 days, the lowest price for a flight from Knoxville to Myrtle Beach was $253 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Myrtle Beach?

    No

  • Which aircraft models fly most regularly from Knoxville to Myrtle Beach?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Myrtle Beach?

    SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and Myrtle Beach, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Myrtle Beach, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Myrtle Beach are Delta and American Airlines. With an average price for the route of $404 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $311 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Myrtle Beach?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Myrtle Beach.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Myrtle Beach?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Myrtle Beach from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Myrtle Beach?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Myrtle Beach with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MYR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Myrtle Beach?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Myrtle Beach from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Knoxville to Myrtle Beach

  • Knoxville McGhee Tyson Airport (TYS) is located approximately 12 miles from downtown Knoxville. The most convenient transport option for you to use to get to the airport would be the Knoxville Airport shuttle transfers. You can reserve a ride at an affordable fee and have the shuttle pick you up from your home, office, hotel, or a famous landmark.
  • Suppose you prefer to drive to TYS, you can leave your car at the airport for extended stay parking. The long-term parking lot is located offsite, about a 10-minute walk to the main Terminal, but you can also take the free shuttle to the main Terminal. The parking lot features both covered and garage parking spaces and charges affordable rates daily. It applies a free cancellation policy if you have a last-minute change of plans.
  • If you are not rushing through TYS to catch your flight; you can enrich your airport experience by enjoying art exhibitions at the airport. The art exhibitions feature around 40 to 45 exquisite art pieces of all styles and genres by regional artists. You will find the display of artwork in the secured area behind McGhee Tyson Airport's security gate checkpoint.
  • Myrtle Beach International Airport (MYR) features an airport concierge service to make your post-arrival procedures less stressful. At an affordable fee, you can book Airssist before your arrival. A professional will meet you at your aircraft, assist you with your carry-on luggage, help you trace your baggage, fast track clearance at security checkpoints and immigration, and connect you to your ground transportation.
  • MYR also has facilities to cater to the needs of differently-abled passengers. The airport has a Flight Information Display System (FIDS) to page passengers with hearing and visual impairments. Telecommunication Devices for the Deaf (TDD) are available throughout the terminals. Wheelchairs are also available, and you may book in advance or request one upon arrival. The airport also has a quiet room in the baggage claim area for passengers with special needs to destress.

Reviews of the top airlines flying from Knoxville to Myrtle Beach

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Myrtle Beach. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Myrtle Beach? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8007 reviews
8.5Crew
7.9Entertainment
7.3Food
8.1Boarding
7.9Comfort
Airline reviews

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

6.0 GoodJeff, Dec 2025
JFK - MIA
Read more Delta reviews

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

Everything you need to know for your flight from Knoxville to Myrtle Beach

Information on your arrival and departure airports