TYS - MYR

$131 Find Cheap Flights from Knoxville to Myrtle Beach

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Myrtle Beach departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Myrtle Beach

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Myrtle Beach, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Myrtle Beach, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$255
Typical prices: $298-$499
Multiple Airlines
Thu 7/16Tue 7/21
TYS - MYR • 1 stop
Cheapest one-way
$131
Typical prices: $216-$253
Multiple Airlines
Wed 7/22
TYS - MYR • 1 stop
Top airlines
Cheapest • from $265 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
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Nonstop flights
Not available
There are currently no direct flights between Knoxville and Myrtle Beach. You'll need at least 1 connection.
Insights
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Insights
Top layover airports
Cheapest • Avg $382 (round-trip)
Shortest trip • 3h 37m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Myrtle Beach!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Myrtle Beach (TYS-MYR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Myrtle Beach that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Myrtle Beach

Thu, Jul 16 - Tue, Jul 21
Multiple Airlines Logo
9:11 pm - 9:50 am
TYS
-
MYR
12h 39m
1 stop
Multiple Airlines Logo
3:53 pm - 5:59 pm
MYR
-
TYS
26h 06m
1 stop
$255Multiple Airlines
Tue, Jul 7 - Tue, Jul 28
American Airlines Logo
4:07 pm - 9:43 pm
TYS
-
MYR
5h 36m
1 stop
American Airlines Logo
6:51 am - 10:38 am
MYR
-
TYS
3h 47m
1 stop
$265American Airlines
Thu, Jul 16 - Sun, Jul 19
Multiple Airlines Logo
9:11 pm - 9:50 am
TYS
-
MYR
12h 39m
1 stop
Multiple Airlines Logo
2:58 pm - 11:03 pm
MYR
-
TYS
8h 05m
1 stop
$270Multiple Airlines
Mon, Sep 14 - Wed, Sep 16
Southwest Logo
8:25 am - 1:50 pm
TYS
-
MYR
5h 25m
1 stop
Southwest Logo
2:25 pm - 7:50 pm
MYR
-
TYS
5h 25m
1 stop
$273Southwest
Wed, Sep 16 - Wed, Sep 30
Southwest Logo
7:00 am - 5:40 pm
TYS
-
MYR
10h 40m
2 stops
Southwest Logo
11:00 am - 7:50 pm
MYR
-
TYS
8h 50m
2 stops
$275Southwest
Wed, Jul 15 - Wed, Jul 22
Southwest Logo
7:10 am - 9:15 pm
TYS
-
MYR
14h 05m
2 stops
Southwest Logo
2:10 pm - 9:20 pm
MYR
-
TYS
7h 10m
1 stop
$276Southwest
Mon, Sep 14 - Wed, Sep 16
Southwest Logo
8:25 am - 1:50 pm
TYS
-
MYR
5h 25m
1 stop
Southwest Logo
8:15 am - 6:55 pm
MYR
-
TYS
10h 40m
2 stops
$278Southwest
Sat, Jul 4 - Tue, Jul 14
American Airlines Logo
5:00 am - 8:36 am
TYS
-
MYR
3h 36m
1 stop
American Airlines Logo
4:16 pm - 10:23 pm
MYR
-
TYS
6h 07m
1 stop
$280American Airlines
Thu, Aug 6 - Thu, Aug 13
Delta Logo
6:12 pm - 11:30 pm
TYS
-
MYR
5h 18m
1 stop
Delta Logo
7:02 pm - 11:52 pm
MYR
-
TYS
4h 50m
1 stop
$281Delta
Sat, Jul 4 - Tue, Jul 14
Southwest Logo
7:00 am - 1:20 pm
TYS
-
MYR
6h 20m
1 stop
Southwest Logo
10:25 am - 9:20 pm
MYR
-
TYS
10h 55m
2 stops
$285Southwest
Booking Insights

KAYAK's insights & trends for Knoxville to Myrtle Beach flights

Get data-powered insights and trends into flights from Knoxville to Myrtle Beach to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Myrtle Beach?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Myrtle Beach departing in July.

What is the cheapest month to fly from Knoxville to Myrtle Beach?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Myrtle Beach, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Myrtle Beach is January, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $585 and $544 respectively.

Good to know

Low seasonAugust
Cheapest flight$131
Best time to beat the crowds with an average 34% drop in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Knoxville to Myrtle Beach

When to book flights from Knoxville to Myrtle Beach

Are your dates flexible? Find out the best times to travel from Knoxville to Myrtle Beach based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Myrtle Beach

  • Does Knoxville McGhee Tyson Airport allow passengers to travel with animals?

    Yes. TYS allows approved service animals to accompany passengers. Service animals must be on a leash while in the airport. You will find animal relief areas for your furry friend on the West side of the Terminal, near the west surface or economy lot crosswalk.

  • Does Knoxville McGhee Tyson Airport have any amenities for nursing mothers?

    Yes. Traveling nursing mothers departing from TYS can enjoy the privacy of the private Mamava pod located past the security checkpoint opposite the food concession area. The pod is lockable, self-contained, and has a comfortable sitting space, a fold-down table, and an electrical outlet for plugging in a breast pump.

  • What ground transportation options do I have upon arrival at MYR?

    You can choose any of the following six ground transportation options upon arrival; public transportation, taxi cab service, rideshare service, hotel shuttle, limousine service, or car rental service. Taxicab service, available on a first-come, first-serve basis, is located outside Door 6 at Baggage Claim. Public Transport is the most affordable and the nearest bus stop is Jet port road.

  • Does Myrtle Beach International Airport have lounges?

    Yes. You can get access to MYR business lounge. The luxury airport lounge is open to passengers from all classes, and it features a comfortable sitting area, access to snacks and drinks, conference facilities and newspapers and magazines to keep you entertained.

  • What is the cheapest flight from Knoxville to Myrtle Beach?

    In the last 5 days, the lowest price for a flight from Knoxville to Myrtle Beach was $131 for a one-way ticket and $255 for a round-trip.

  • Do I need a passport to fly between Knoxville and Myrtle Beach?

    No

  • Which aircraft models fly most regularly from Knoxville to Myrtle Beach?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Myrtle Beach?

    SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and Myrtle Beach, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Myrtle Beach, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Myrtle Beach are Delta and American Airlines. With an average price for the route of $537 and an overall rating of 7.8, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $348 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Knoxville to Myrtle Beach?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Myrtle Beach.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Myrtle Beach?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Myrtle Beach from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Myrtle Beach?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Myrtle Beach with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MYR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Myrtle Beach?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Myrtle Beach from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Knoxville to Myrtle Beach

  • Knoxville McGhee Tyson Airport (TYS) is located approximately 12 miles from downtown Knoxville. The most convenient transport option for you to use to get to the airport would be the Knoxville Airport shuttle transfers. You can reserve a ride at an affordable fee and have the shuttle pick you up from your home, office, hotel, or a famous landmark.
  • Suppose you prefer to drive to TYS, you can leave your car at the airport for extended stay parking. The long-term parking lot is located offsite, about a 10-minute walk to the main Terminal, but you can also take the free shuttle to the main Terminal. The parking lot features both covered and garage parking spaces and charges affordable rates daily. It applies a free cancellation policy if you have a last-minute change of plans.
  • If you are not rushing through TYS to catch your flight; you can enrich your airport experience by enjoying art exhibitions at the airport. The art exhibitions feature around 40 to 45 exquisite art pieces of all styles and genres by regional artists. You will find the display of artwork in the secured area behind McGhee Tyson Airport's security gate checkpoint.
  • Myrtle Beach International Airport (MYR) features an airport concierge service to make your post-arrival procedures less stressful. At an affordable fee, you can book Airssist before your arrival. A professional will meet you at your aircraft, assist you with your carry-on luggage, help you trace your baggage, fast track clearance at security checkpoints and immigration, and connect you to your ground transportation.
  • MYR also has facilities to cater to the needs of differently-abled passengers. The airport has a Flight Information Display System (FIDS) to page passengers with hearing and visual impairments. Telecommunication Devices for the Deaf (TDD) are available throughout the terminals. Wheelchairs are also available, and you may book in advance or request one upon arrival. The airport also has a quiet room in the baggage claim area for passengers with special needs to destress.

Reviews of the top airlines flying from Knoxville to Myrtle Beach

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Myrtle Beach. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Myrtle Beach? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8420 reviews
8.1Boarding
7.8Entertainment
8.5Crew
7.8Comfort
7.2Food
Airline reviews

Flight got canceled 4 times, missed my connecting flight due to delays, have to wait to go home tomorrow

2.0 MediocreChelsea, Jun 2026
DAL - ATL
Read more Delta reviews

Flight got canceled 4 times, missed my connecting flight due to delays, have to wait to go home tomorrow

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Great experience nice pilot very soft and easy landing and take off

We sat on the runway for over an hour before departure. That was unwelcome.

Horrible. Faucet in sink not working, wifi not working. Didn’t bring food or snacks

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

From checking to boarding, it was a seamless experience. The service agents were so helpful. The flight crew was so pleasant.

Gate agent showed up 20 minutes before boarding and was not at all friendly. Had to take this flight due to the one on the day before being cancelled and any later options were already full with long standby lists. Despite having paid for Delta Comfort seats, Delta did not allow me (or anyone) to choose their seat. The agent assigned them for everyone just prior to boarding. Self seat selection was allowed on the original flight. Flight staff was great - very friendly.

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

Flight cancelled. Twice. And no communication. No gate agent. Went past boarding time and had to go and see email from AA. Airport communication was bad

I love the e fact that the staff communicated swiftly when my flight was delayed and gate number changed

It was awful. The communication between corporate and the crew on the ground left more to be desired. The crew even said that Corporate was waiting on answers because they themselves didn't know. Every hour, there was a new excuse. I also understood that passengers were angry, but the crew should have done a better job at crowd control. There was a racial exchange between passengers that could've been avoided has the crew acted sooner.

Delayed and horrible communication and sat on flight for an hour before taking off

Flight was delayed three times and we had an international connecting flight which we would’ve missed but AA manage to find us a flight that allowed us to catch and we made our international flight. However, due to the flight change, I’m in Amman, Jordan missing all 4 bags. It’s been a nightmare. Been waiting since June 17 and today is June 20th. Still without luggage. Customer service wait times are two hours and I get disconnected while waiting. I’ll update when/if my luggage arrives. Every day is costing money in a hotel in Amman. I can’t continue my trip to Palestine until the luggage arrives. Then, I will be updating my review.

They did not offer coffee on a 7am flight…awful!!

Plane temperature was so hot that everyone on the plane was sweating. Departure gates changed 3 times in the hour before the flight. Internet service was so poor in the terminal that updates weren't always being received.

We had a mechanical delay which made us 90 minutes late (9:30 PM) then land and put into the penalty box because a plane was in our gate? What the hell! We should get priority.Damn American.

Check in for 5am flight at RDU was hampered by American check in counters being seriously understaffed , was told even supervisor called out. Took so long in line for special services check in that we missed our 5am departure even after arriving at 3:30am. Had to be rescheduled to later flight from Charlotte to St Thomas.

Delayed flight due to maintenance and I have had multiple delayed flights due to maintenance in the last month plus

Everything you need to know for your flight from Knoxville to Myrtle Beach

Information on your arrival and departure airports