Which airports can I use when flying from Knoxville to Santa Ana?

Flights from Knoxville to Santa Ana usually depart from Knoxville McGhee Tyson (TYS) and arrive at Santa Ana J. Wayne/Orange Cnty (SNA).

What cabin classes can I book on flights from Knoxville to Santa Ana?

Two cabin classes are available on flights from Knoxville to Santa Ana: • Economy Class • First Class

Which airports do connecting flights from Knoxville to Santa Ana pass through?

One-stop flights from Knoxville to Santa Ana most commonly connect through: • Dallas/Fort Worth (DFW) - 73% of one-stop connections • Denver Intl (DEN) - 13% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 8% of one-stop connections • Las Vegas Harry Reid Intl (LAS) - 3% of one-stop connections

Can I save money by using flexible dates for flights from Knoxville to Santa Ana?

Yes. Flexible dates can save you up to 41% on flights from Knoxville to Santa Ana. Saturday is the cheapest departure day at $468 round-trip on average, while Sunday is the most expensive at $792, a difference of $324. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

What popular places can I visit in Santa Ana?

Some of the most popular sights in Santa Ana are Embassy Suites by Hilton Santa Ana Orange County Airport, Santa Ana Zoo and Old Orange County Courthouse. These are among the most viewed places in Santa Ana on KAYAK.

How long is a flight from Knoxville to Santa Ana?

A nonstop flight from Knoxville to Santa Ana takes 00m, covering 1,918 miles.

Do I need a passport to fly from Knoxville to Santa Ana?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Knoxville to Santa Ana changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $363 to $1,593. That means the highest observed fare was about 4x higher than the lowest one.

How are flight prices from Knoxville to Santa Ana looking right now?

One-way fares from Knoxville to Santa Ana are currently higher than usual. Average one-way flight prices are about $333, which is 9% above the typical average for this route.

How much time can I save by choosing a different layover airport from Knoxville to Santa Ana?

Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 7h 05m, compared with 7h 06m via Atlanta Hartsfield-Jackson (ATL) and 7h 13m via Denver Intl (DEN).

What is the time difference between Knoxville and Santa Ana?

Santa Ana is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Santa Ana J. Wayne/Orange Cnty Airport (SNA)?

Santa Ana J. Wayne/Orange Cnty Airport (SNA) hosts 5 major car rental companies, with daily rates averaging $58 for economy cars. Top options include: • Dollar • Thrifty • Hertz • Budget • Alamo

How much should I expect to pay for a Knoxville to Santa Ana flight?

Round-trip flights from Knoxville to Santa Ana range from $427 to $693, with an average of $554 over the past 12 months. Anything below $427 counts as a good deal.

How much is a round-trip flight from Knoxville to Santa Ana?

Round-trip flights from Knoxville to Santa Ana typically range from $427 to $693. The lowest price found in the past 5 days was $363, on American Airlines.

What's the cheapest day of the week to fly from Knoxville to Santa Ana?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Knoxville to Santa Ana. It’s 16% cheaper than the average day, while Sunday is the most expensive, with prices 42% higher.

What’s the cheapest month to fly from Knoxville to Santa Ana?

•February is the cheapest month to fly from Knoxville to Santa Ana at $448 round-trip. •November ($740) and October ($653) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 65% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Which airline is the cheapest to fly from Knoxville to Santa Ana?

American Airlines ($363) and United Airlines ($363) are the cheapest airlines to fly round-trip from Knoxville to Santa Ana according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Knoxville to Santa Ana?

Dallas/Fort Worth (DFW) is the most popular layover for the Knoxville to Santa Ana route. 73% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via DFW.

What is the cheapest layover airport when flying from Knoxville to Santa Ana?

Flights via Las Vegas Harry Reid Intl (LAS) offer the most affordable fares, with an average round-trip price of $365. Based on KAYAK data over the past 3 months.

When flying from Knoxville to Santa Ana which airport offers the shortest layover?

Dallas/Fort Worth (DFW) had the shortest average connection time for Knoxville to Santa Ana layovers at 4h 11m over the past 3 months.

$144 CHEAP FLIGHTS from Knoxville to John Wayne (Santa Ana) (TYS - SNA)

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Cheapest round-trip

$363

Typical prices: $427-$693

American Airlines

Sat 1/6Sat 1/13

TYS - SNA • 1 stop

Cheapest one-way

$144

Typical prices: $218-$387

Multiple Airlines

Thu 11/22

TYS - SNA • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Knoxville and Santa Ana. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

February

Cheapest • 19% price drop

May

Most popular

Good to know

Top layover airports

Las Vegas Harry Reid Intl (LAS)

Cheapest • Avg $365 (round-trip)

Dallas/Fort Worth (DFW)

Shortest trip • 7h 05m (one-way)

Insights

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We hope you love your trip to Santa Ana!

Flight Deals

Cheap Flights from Knoxville to Santa Ana (TYS-SNA)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Knoxville to Santa Ana

Wed, Jan 6 - Wed, Jan 13

8:20 am - 12:22 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

7h 02m1 stop Dallas/Fort Worth

1:12 pm - 11:19 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

7h 07m1 stop Dallas/Fort Worth

$363American Airlines

Wed, Jan 6 - Wed, Jan 13

2:04 pm - 8:23 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

9h 19m1 stop Washington, D.C. Dulles Intl

12:04 pm - 9:59 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

6h 55m1 stop Houston George Bush Intcntl

$363United Airlines

Wed, Jan 6 - Wed, Jan 13

4:28 pm - 8:44 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

7h 16m1 stop Denver Intl

6:49 am - 9:05 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

11h 16m2 stops Denver Intl Chicago O'Hare Intl

$368United Airlines

Sun, Dec 20 - Thu, Dec 24

1:50 pm - 4:28 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

29h 38m1 stop Phoenix Sky Harbor Intl

11:43 am - 10:14 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

7h 31m1 stop Phoenix Sky Harbor Intl

$369Multiple Airlines

Sun, Dec 20 - Fri, Dec 25

5:30 am - 10:04 amTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

7h 34m1 stop Dallas/Fort Worth

2:24 pm - 11:41 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

6h 17m1 stop Dallas/Fort Worth

$403American Airlines

Sun, Dec 20 - Fri, Dec 25

3:45 pm - 9:05 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

8h 20m2 stops Dallas Love Field Phoenix Sky Harbor Intl

7:00 am - 7:50 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

9h 50m2 stops Austin Bergstrom Nashville Intl

$413Southwest

Sun, Dec 20 - Thu, Dec 24

1:50 pm - 6:33 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

31h 43m2 stops Phoenix Sky Harbor Intl Las Vegas Harry Reid Intl

11:43 am - 10:14 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

7h 31m1 stop Phoenix Sky Harbor Intl

$416Multiple Airlines

Wed, Jan 6 - Wed, Jan 13

6:45 am - 2:50 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

11h 05m2 stops Nashville Intl Denver Intl

6:45 am - 3:55 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

6h 10m1 stop Denver Intl

$422Southwest

Mon, Mar 22 - Tue, Mar 30

7:07 am - 11:13 amTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

7h 06m1 stop Atlanta Hartsfield-Jackson

11:55 am - 11:46 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

8h 51m1 stop Atlanta Hartsfield-Jackson

$497Delta

Sat, Mar 20 - Thu, Apr 1

5:30 am - 11:13 amTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

8h 43m1 stop Atlanta Hartsfield-Jackson

11:55 am - 11:46 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

8h 51m1 stop Atlanta Hartsfield-Jackson

$497Delta

Recent last minute flight deals from Knoxville to Santa Ana

Tue, Nov 10 - Sun, Nov 22

8:30 am - 8:30 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

15h 00m2 stops Orlando Sanford Intl Provo

2:12 pm - 12:42 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

19h 30m1 stop Las Vegas Harry Reid Intl

$543Multiple Airlines

Tue, Nov 10 - Tue, Nov 24

8:30 am - 8:30 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

15h 00m2 stops Orlando Sanford Intl Provo

2:12 pm - 9:05 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

27h 53m1 stop Las Vegas Harry Reid Intl

$593Multiple Airlines

Fri, Nov 6 - Fri, Nov 13

1:29 pm - 7:11 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

8h 42m1 stop Las Vegas Harry Reid Intl

9:41 am - 5:33 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

28h 52m2 stops Colorado Springs Tampa St. Petersburg

$611Multiple Airlines

Tue, Nov 10 - Sun, Nov 22

9:00 am - 2:59 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

8h 59m1 stop Denver Intl

10:47 am - 8:54 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

7h 07m1 stop Chicago O'Hare Intl

$732United Airlines

Tue, Nov 10 - Tue, Nov 24

7:05 am - 2:00 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

9h 55m2 stops Nashville Intl Denver Intl

6:45 am - 6:40 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

8h 55m2 stops Phoenix Sky Harbor Intl Dallas Love Field

$750Southwest

Tue, Nov 10 - Sat, Nov 21

5:05 pm - 9:19 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

7h 14m1 stop Denver Intl

11:10 am - 10:32 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

8h 22m1 stop Denver Intl

$768United Airlines

Tue, Nov 10 - Tue, Nov 24

4:15 pm - 9:45 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

8h 30m1 stop Denver Intl

9:10 am - 6:40 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

6h 30m1 stop Dallas Love Field

$782Southwest

Tue, Nov 10 - Sun, Nov 22

7:05 am - 2:45 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

10h 40m2 stops Nashville Intl Phoenix Sky Harbor Intl

8:00 am - 8:35 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

9h 35m2 stops Dallas Love Field Nashville Intl

$792Southwest

Tue, Nov 10 - Fri, Nov 20

4:59 pm - 9:24 pmTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

7h 25m1 stop Chicago O'Hare Intl

1:17 pm - 11:32 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

7h 15m1 stop Dallas/Fort Worth

$863American Airlines

Tue, Nov 10 - Fri, Nov 20

5:30 am - 11:50 amTYS Knoxville McGhee Tyson-SNA Santa Ana J. Wayne/Orange Cnty

9h 20m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

1:17 pm - 11:32 pmSNA Santa Ana J. Wayne/Orange Cnty-TYS Knoxville McGhee Tyson

7h 15m1 stop Dallas/Fort Worth

$868American Airlines

Booking Insights

Price, demand and travel trends for Knoxville to Santa Ana flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Knoxville to Santa Ana? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Santa Ana departing in january.
What's the cheapest day of the week to fly from Knoxville to Santa Ana?: Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from Knoxville to Santa Ana. It’s 16% cheaper than the average day, while Sunday is the most expensive, with prices 42% higher.
What’s the cheapest month to fly from Knoxville to Santa Ana? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Knoxville to Santa Ana, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •February is the cheapest month to fly from Knoxville to Santa Ana at $448 round-trip.
•November ($740) and October ($653) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 65% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	December
High season	May
Cheapest flight	$144

Beat the crowds with an average 34% drop in travelers.

The most popular month to fly with an average 31% increase in travelers.

One-way flight from Knoxville to Santa Ana

When to book flights from Knoxville to Santa Ana

Are your dates flexible? Find out the best times to travel from Knoxville to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Knoxville to Santa Ana?
Two cabin classes are available on flights from Knoxville to Santa Ana:

• Economy Class
• First Class
How long is a flight from Knoxville to Santa Ana?
A nonstop flight from Knoxville to Santa Ana takes 00m, covering 1,918 miles.
Do I need a passport to fly from Knoxville to Santa Ana?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Knoxville to Santa Ana flight?
Round-trip flights from Knoxville to Santa Ana range from $427 to $693, with an average of $554 over the past 12 months. Anything below $427 counts as a good deal.
Have flight prices from Knoxville to Santa Ana changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $363 to $1,593. That means the highest observed fare was about 4x higher than the lowest one.
How are flight prices from Knoxville to Santa Ana looking right now?
One-way fares from Knoxville to Santa Ana are currently higher than usual. Average one-way flight prices are about $333, which is 9% above the typical average for this route.
What car rental options are available at Santa Ana J. Wayne/Orange Cnty Airport (SNA)?
Santa Ana J. Wayne/Orange Cnty Airport (SNA) hosts 5 major car rental companies, with daily rates averaging $58 for economy cars. Top options include:

• Dollar
• Thrifty
• Hertz
• Budget
• Alamo
Which airports can I use when flying from Knoxville to Santa Ana?
Flights from Knoxville to Santa Ana usually depart from Knoxville McGhee Tyson (TYS) and arrive at Santa Ana J. Wayne/Orange Cnty (SNA).
Which airports do connecting flights from Knoxville to Santa Ana pass through?
One-stop flights from Knoxville to Santa Ana most commonly connect through:

• Dallas/Fort Worth (DFW) - 73% of one-stop connections
• Denver Intl (DEN) - 13% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 8% of one-stop connections
• Las Vegas Harry Reid Intl (LAS) - 3% of one-stop connections
Can I save money by using flexible dates for flights from Knoxville to Santa Ana?
Yes. Flexible dates can save you up to 41% on flights from Knoxville to Santa Ana. Saturday is the cheapest departure day at $468 round-trip on average, while Sunday is the most expensive at $792, a difference of $324.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How much time can I save by choosing a different layover airport from Knoxville to Santa Ana?
Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 7h 05m, compared with 7h 06m via Atlanta Hartsfield-Jackson (ATL) and 7h 13m via Denver Intl (DEN).
What is the time difference between Knoxville and Santa Ana?
Santa Ana is 3 hours behind Knoxville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.
What popular places can I visit in Santa Ana?
Some of the most popular sights in Santa Ana are Embassy Suites by Hilton Santa Ana Orange County Airport, Santa Ana Zoo and Old Orange County Courthouse. These are among the most viewed places in Santa Ana on KAYAK.

If your dates are flexible, aim for a Saturday departure and avoid flying on Sunday. On this route, Saturday flights average $468, about $324 less than Sunday fares (41% savings) based on the last 12 months.
If you can choose when to travel, plan your Knoxville to Santa Ana trip for February. Fares historically average $448 round-trip in that month - typically $292 less than the most expensive month, which is November (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Ana J. Wayne/Orange Cnty Airport.

• voco Orange County - Airport by IHG
• Hotel Zessa Orange County Airport, a DoubleTree by Hilton
• Courtyard by Marriott Santa Ana Orange County

More options for your flight from Knoxville to Santa Ana

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Complete your trip to Santa Ana with a hotel stay or car rental

Car rentals in Santa Ana

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TYS - SNA

$144 Find Cheap Flights from Knoxville to John Wayne (Santa Ana) - Compare and Save

Everything you should know

Cheap Flights from Knoxville to Santa Ana (TYS-SNA)

Recent round-trip flight deals from Knoxville to Santa Ana

Recent one-way flight deals from Knoxville to Santa Ana

Recent last minute flight deals from Knoxville to Santa Ana

Price, demand and travel trends for Knoxville to Santa Ana flights

How much is a round-trip flight from Knoxville to Santa Ana?

What's the cheapest day of the week to fly from Knoxville to Santa Ana?

What’s the cheapest month to fly from Knoxville to Santa Ana?

Which airline is the cheapest to fly from Knoxville to Santa Ana?

What’s the most popular layover airport when flying from Knoxville to Santa Ana?

What is the cheapest layover airport when flying from Knoxville to Santa Ana?

When flying from Knoxville to Santa Ana which airport offers the shortest layover?

Key details for Knoxville to Santa Ana flights

Low season

High season

Cheapest flight

When to book flights from Knoxville to Santa Ana

Your Knoxville to Santa Ana flight questions, answered

Your guide to booking Knoxville to Santa Ana flights

More options for your flight from Knoxville to Santa Ana

Complete your trip to Santa Ana with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Knoxville to Santa Ana

Find direct flights to and from Knoxville and Santa Ana

Flights from domestic origins to Santa Ana

Flights to other popular destinations

Find deals for your return flight