$276 Find Cheap Flights from St. Louis to Brussels - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$579
Typical prices: $641-$1,399
Air Canada
Sat 12/1Sat 12/8
STL - BRU • 2 stops
Cheapest one-way
$276
Typical prices: $490-$717
Multiple Airlines
Fri 10/19
STL - BRU • 3 stops
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Brussels. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 47% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Frankfurt am Main (FRA)
Cheapest • Avg $909 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 12h 23m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Brussels (STL-BRU)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Brussels

Tue, Dec 1 - Tue, Dec 8
Air Canada Logo
6:30 am - 7:50 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
42h 20m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl
Air Canada Logo
10:00 am - 10:59 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
43h 59m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl
$579Air Canada
Wed, Nov 4 - Wed, Nov 11
Air Canada Logo
9:40 am - 7:50 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
15h 10m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl
Air Canada Logo
10:00 am - 9:40 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
18h 40m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl
$584Air Canada
Sun, Nov 8 - Tue, Nov 17
United Airlines Logo
1:08 pm - 8:55 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
12h 47m1 stop Chicago O'Hare Intl
United Airlines Logo
11:55 am - 9:40 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
16h 45m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
$587United Airlines
Sun, Nov 8 - Tue, Nov 17
United Airlines Logo
7:30 am - 8:55 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
18h 25m1 stop Chicago O'Hare Intl
United Airlines Logo
10:10 am - 6:09 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
14h 59m1 stop Chicago O'Hare Intl
$587United Airlines
Wed, Feb 10 - Wed, Feb 17
United Airlines Logo
9:22 am - 8:55 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
16h 33m1 stop Chicago O'Hare Intl
United Airlines Logo
10:00 am - 12:40 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
33h 40m2 stops Montreal Pierre Elliott Trudeau Intl Newark
$587United Airlines
Sun, Nov 8 - Tue, Nov 17
Air Canada Logo
6:50 pm - 7:50 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
30h 00m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl
Air Canada Logo
10:00 am - 3:43 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
36h 43m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl
$593Air Canada
Wed, Nov 4 - Wed, Nov 11
Lufthansa Logo
1:00 pm - 7:15 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
11h 15m1 stop Washington, D.C. Dulles Intl
Lufthansa Logo
10:10 am - 9:40 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
18h 30m1 stop Chicago O'Hare Intl
$595Lufthansa
Sun, Nov 8 - Tue, Nov 17
American Airlines Logo
5:29 pm - 4:40 pmSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
16h 11m2 stops Chicago O'Hare Intl London Heathrow
American Airlines Logo
7:00 am - 6:17 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
18h 17m2 stops Madrid Barajas Chicago O'Hare Intl
$598American Airlines
Wed, Mar 17 - Sat, Mar 27
Lufthansa Logo
4:40 pm - 10:10 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
11h 30m1 stop Frankfurt am Main
Lufthansa Logo
9:30 am - 1:25 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
33h 55m1 stop Frankfurt am Main
$846Lufthansa
Sat, Nov 7 - Fri, Nov 13
Lufthansa Logo
1:00 pm - 7:15 amSTL  Lambert-St Louis-BRU Brussels Bruxelles-National
11h 15m1 stop Washington, D.C. Dulles Intl
Lufthansa Logo
7:40 pm - 9:40 pmBRU  Brussels Bruxelles-National-STL Lambert-St Louis
33h 00m2 stops Munich Franz Josef Strauss Chicago O'Hare Intl
$1,281Lufthansa
Booking Insights

Price, demand and travel trends for St. Louis to Brussels flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from St. Louis to Brussels with more confidence.

How much is a round-trip flight from St. Louis to Brussels?

Round-trip flights from St. Louis to Brussels start at $579. Prices are below average for this route right now, with typical round-trip fares ranging from $641 to $1,399. The lowest price found in the past 5 days was $579 on Air Canada.

What's the cheapest day of the week to fly from St. Louis to Brussels?

Thursday is the cheapest day of the week to fly from St. Louis to Brussels, it is 31% cheaper than the average day. Tuesday is the most expensive day with flight prices 53% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from St. Louis to Brussels?

•February is the cheapest month to fly from St. Louis to Brussels at $516 round-trip.
•December ($2,200) and November ($1,506) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 326% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for St. Louis to Brussels flights

Low season

June

Cheapest flight

$276
Best time to beat the crowds but there is an average 40% increase in price.
Most popular time to fly and prices are also 30% lower on average.
Flight from St. Louis to Brussels Bruxelles-National Airport

When to book flights from St. Louis to Brussels

Are your dates flexible? Find out the best times to travel from St. Louis to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Brussels flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from St. Louis to Brussels?

    Flights from St. Louis to Brussels usually depart from Lambert-St Louis (STL) and may arrive at several airports in Brussels area, including Brussels Bruxelles-National (BRU) and Charleroi Brussels (CRL).

  • What cabin classes can I book on flights from St. Louis to Brussels?

    Four cabin classes are available on flights from St. Louis to Brussels:

    • Economy Class
    • Premium Economy Class
    • Business Class
    • First Class

    Prices vary by airline.

  • Which airports do connecting flights from St. Louis to Brussels pass through?

    One-stop flights from St. Louis to Brussels most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 59% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 19% of one-stop connections
    • Frankfurt am Main (FRA) - 19% of one-stop connections
    • Washington, D.C. Dulles Intl (IAD) - 3% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from St. Louis to Brussels?

    Yes. Being flexible with your travel dates can save you up to 55% on the St. Louis to Brussels route. Thursday is the cheapest departure day at $685 round-trip on average, while Tuesday is the most expensive at $1,506, a difference of $821. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Brussels?

    Some of the most popular sights in Brussels are Grand Place, King Baudouin Stadium and Brussels Exhibition Centre. These are among the most viewed places in Brussels on KAYAK.

  • How long is a flight from St. Louis to Brussels?

    A nonstop flight from St. Louis to Brussels takes 0h 00m, covering 4,390 miles.

  • Do I need a passport to fly from St. Louis to Brussels?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How are flight prices from St. Louis to Brussels looking right now?

    One-way fares from St. Louis to Brussels are currently higher than usual. Average one-way flight prices are about $700, which is 14% above the typical average for this route.

  • How much time can I save by choosing a different layover airport from St. Louis to Brussels?

    Flying via Frankfurt am Main (FRA) gives the shortest average 1-stop total travel time at 11h 53m, compared with 12h 23m via Chicago O'Hare Intl (ORD) and 12h 42m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between St. Louis and Brussels?

    Brussels is 7 hours ahead of St. Louis (Central European Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available in Brussels?

    Since Brussels is served by multiple airports, car rental options and rates can vary depending on which one you fly into.
    Near Brussels Bruxelles-National Airport (BRU) — daily rates from around $20:

    • Hertz
    • Alamo
    • keddy by Europcar
    • Europcar
    • Sixt

    Near Charleroi Brussels Airport (CRL) — daily rates from around $22:

    • keddy by Europcar
    • Europcar
    • Hertz
    • Sixt
    • Thrifty

  • How much should I expect to pay for a St. Louis to Brussels flight?

    Round-trip flights from St. Louis to Brussels range from $641 to $1,399, with an average of $981 over the past 12 months. Anything below $641 counts as a good deal.

Your guide to booking St. Louis to Brussels flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Tuesday. On this route, Thursday flights average $685 - about $821 less than Tuesday (55% savings) based on the last 12 months.
  • If you can choose when to travel, plan your St. Louis to Brussels trip for February. Fares historically average $516 round-trip in that month - typically $1,684 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Brussels Bruxelles-National Airport.
    - NH Brussels Airport
    - Crowne Plaza Brussels Airport By IHG

More options for your flight from St. Louis to Brussels

Complete your trip to Brussels with a hotel stay or car rental

Car rentals in Brussels
Hotels in Brussels
Vacations in Brussels