STL - DSM

$118 Find Cheap Flights from St. Louis to Des Moines - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$209
American Airlines
Tue 8/11Mon 8/17
STL - DSM • 1 stop
Cheapest one-way
$118
United Airlines
Sat 8/15
STL - DSM • 1 stop
Top airlines
American Airlines
Cheapest • from $209 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
April
Cheapest • 100% price drop
July
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Tue, Aug 11 - Mon, Aug 17
American Airlines Logo
8:07 pm - 12:20 am
STL
-
DSM
4h 13m
1 stop
American Airlines Logo
7:49 pm - 12:14 am
DSM
-
STL
4h 25m
1 stop
$209American Airlines
Mon, Sep 14 - Thu, Sep 17
Southwest Logo
3:15 pm - 10:10 pm
STL
-
DSM
6h 55m
2 stops
Southwest Logo
5:40 am - 9:15 am
DSM
-
STL
3h 35m
1 stop
$214Southwest
Sat, Aug 29 - Sat, Sep 5
Southwest Logo
8:30 am - 7:25 pm
STL
-
DSM
10h 55m
2 stops
Southwest Logo
5:30 am - 11:05 am
DSM
-
STL
5h 35m
1 stop
$220Southwest
Sat, Aug 15 - Sat, Aug 22
United Airlines Logo
12:59 pm - 5:28 pm
STL
-
DSM
4h 29m
1 stop
United Airlines Logo
8:00 am - 12:03 pm
DSM
-
STL
4h 03m
1 stop
$235United Airlines
Sat, Aug 15 - Sat, Aug 22
Southwest Logo
5:45 am - 11:30 am
STL
-
DSM
5h 45m
1 stop
Southwest Logo
5:30 am - 12:35 pm
DSM
-
STL
7h 05m
2 stops
$240Southwest
Mon, Sep 14 - Thu, Sep 17
Southwest Logo
3:45 pm - 10:10 pm
STL
-
DSM
6h 25m
2 stops
Southwest Logo
5:40 am - 3:20 pm
DSM
-
STL
9h 40m
2 stops
$250Southwest
Tue, Aug 11 - Mon, Aug 17
Multiple Airlines Logo
8:08 pm - 1:34 pm
STL
-
DSM
17h 26m
1 stop
Multiple Airlines Logo
7:05 pm - 1:21 pm
DSM
-
STL
18h 16m
2 stops
$261Multiple Airlines
Tue, Aug 11 - Mon, Aug 17
Multiple Airlines Logo
8:08 pm - 1:34 pm
STL
-
DSM
17h 26m
1 stop
Multiple Airlines Logo
7:05 pm - 1:21 pm
DSM
-
STL
18h 16m
2 stops
$262Multiple Airlines
Mon, Oct 12 - Fri, Oct 16
Southwest Logo
6:10 pm - 10:55 pm
STL
-
DSM
4h 45m
1 stop
Southwest Logo
2:00 pm - 11:20 pm
DSM
-
STL
9h 20m
1 stop
$277Southwest
Sat, Aug 29 - Sat, Sep 5
Southwest Logo
8:30 am - 7:25 pm
STL
-
DSM
10h 55m
2 stops
Southwest Logo
5:30 am - 12:35 pm
DSM
-
STL
7h 05m
2 stops
$278Southwest
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Thursday is the cheapest day to fly on average and Monday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Tuesday, with Friday being the most expensive.

What is the cheapest month to fly from St. Louis to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Des Moines is April, where tickets cost $0 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $725 and $680 respectively.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $598 on average.

Find deals

Good to know

Low season

October

Cheapest flight

$118
Best time to beat the crowds with an average 45% drop in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 5 days, the lowest price for a flight from St. Louis to Des Moines was $118 for a one-way ticket and $209 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and JetBlue offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $194 or less one-way.

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4242 reviews
7.5Entertainment
7.0Food
8.1Boarding
8.0Comfort
8.6Crew
Airline reviews

Snacks are always pretzels. Why can't you also offer peanuts ?

6.0 GoodAnonymous, Mar 2026
STL - HOU
Read more Southwest reviews

Snacks are always pretzels. Why can't you also offer peanuts ?

Only downside was the legroom and seat width, which is always a problem unless I spend more for a premium seat.

Very good. Sad to learn Southwest is going start to charge for bags

Exceptional crew! Friendly and professional. Pleasant attitude and treated everyone with respect.

The flight was promptly on schedule and Southwest delivered everything they promised. No excuses for any shortfalls just 100% ownership of their responsibilities and business. The boarding and seating policy is a complete shambles. What started out as a great idea when Southwest first hit the market has been turned into a disaster due to the lack of integrity in many of the people who fly Southwest and take advantage of Southwest generosity at the expense of their fellow passengers.

Crew was excellent - Plane was fine. Media was good, could use more kid shows; Not a fan of the brownie brittle -- snack could be slightly better.

Left on time and arrived early. Brand new plane and no parts missing. Comfortable seats. The actual Captain spoke prior to the flight and reassured everyone about safety. Crew was so nice and fun. Perfect flight!

Everything went smoothly and the plane wasn’t full. It was delayed though. The delay was increased due to a crew change which was frustrating.

Love Southwest! Always a good trip with a happy crew who goes out of their way to be kind and fun.

friendly staff for the most part. they thought we were going to have bad turbulence so no drink service. there wasn't any turbulence. Iwish you had a choice of snacks

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

St. Louis (STL)
Des Moines (DSM)