STL - DSM

$137 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$293
American Airlines
Wed 7/1Tue 7/7
STL - DSM • 1 stop
Cheapest one-way
$137
Typical prices: $191-$209
Multiple Airlines
Sat 7/11
STL - DSM • 2 stops
Top airlines
American Airlines
Cheapest • from $293 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Minneapolis (MSP)
Cheapest • Avg $196 (round-trip)
Minneapolis (MSP)
Shortest trip • 3h 40m (one-way)
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 100% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Wed, Jul 1 - Tue, Jul 7
American Airlines Logo
2:32 pm - 7:35 pm
STL
-
DSM
5h 03m
1 stop
American Airlines Logo
6:33 pm - 12:16 am
DSM
-
STL
5h 43m
1 stop
$293American Airlines
Wed, Jul 1 - Tue, Jul 7
Southwest Logo
5:55 pm - 10:45 pm
STL
-
DSM
4h 50m
1 stop
Southwest Logo
5:20 am - 3:10 pm
DSM
-
STL
9h 50m
2 stops
$298Southwest
Wed, Jul 1 - Tue, Jul 7
Southwest Logo
10:15 am - 10:45 pm
STL
-
DSM
12h 30m
2 stops
Southwest Logo
5:20 am - 2:50 pm
DSM
-
STL
9h 30m
2 stops
$309Southwest
Thu, Jul 2 - Wed, Jul 8
Frontier Logo
7:38 pm - 1:31 pm
STL
-
DSM
17h 53m
1 stop
Frontier Logo
2:19 pm - 7:23 pm
DSM
-
STL
5h 04m
1 stop
$310Frontier
Fri, Jul 3 - Sun, Jul 5
American Airlines Logo
6:16 pm - 12:01 am
STL
-
DSM
5h 45m
1 stop
American Airlines Logo
5:00 am - 8:37 am
DSM
-
STL
3h 37m
1 stop
$319American Airlines
Sat, Oct 17 - Sat, Oct 24
United Airlines Logo
5:36 pm - 11:35 pm
STL
-
DSM
5h 59m
1 stop
United Airlines Logo
6:00 am - 10:48 am
DSM
-
STL
4h 48m
1 stop
$323United Airlines
Thu, Jul 2 - Wed, Jul 8
Southwest Logo
4:00 pm - 10:20 pm
STL
-
DSM
6h 20m
1 stop
Southwest Logo
5:20 am - 2:50 pm
DSM
-
STL
9h 30m
2 stops
$324Southwest
Mon, Jun 15 - Thu, Jun 18
Southwest Logo
6:30 pm - 11:30 pm
STL
-
DSM
5h 00m
1 stop
Southwest Logo
4:40 pm - 10:50 pm
DSM
-
STL
6h 10m
1 stop
$325Southwest
Sat, Oct 17 - Sat, Oct 24
Southwest Logo
1:45 pm - 7:40 pm
STL
-
DSM
5h 55m
1 stop
Southwest Logo
5:40 am - 12:55 pm
DSM
-
STL
7h 15m
2 stops
$328Southwest
Mon, Jun 15 - Thu, Jun 18
Southwest Logo
2:30 pm - 11:30 pm
STL
-
DSM
9h 00m
2 stops
Southwest Logo
4:40 pm - 10:50 pm
DSM
-
STL
6h 10m
1 stop
$330Southwest
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from St. Louis to Des Moines?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from St. Louis to Des Moines departing in July.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Tuesday, with Friday being the most expensive.

What is the cheapest month to fly from St. Louis to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Des Moines is April, where tickets cost $0 (return) on average. On the other hand, the most expensive months are January and July, where the average cost of round-trip tickets is $680 and $663 respectively.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $262 on average.

Find deals

Good to know

Low seasonOctober
Cheapest flight$137
Best time to beat the crowds with an average 44% drop in price.
Most popular time to fly and prices are also 39% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 5 days, the lowest price for a flight from St. Louis to Des Moines was $137 for a one-way ticket and $293 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and JetBlue offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $194 or less one-way.

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4254 reviews
8.1Boarding
7.5Entertainment
8.0Comfort
7.0Food
8.6Crew
Airline reviews

OKay. I sat in the back of the plane and it was really loud between babies and little kids, and adults who.like to talk a lot and loudly most of the flight.

6.0 GoodAnonymous, Jun 2026
MDW - BDL
Read more Southwest reviews

OKay. I sat in the back of the plane and it was really loud between babies and little kids, and adults who.like to talk a lot and loudly most of the flight.

Flight coming out of Buffalo was delayed, so we had to be rescheduled on another flight from Baltimore to Phoenix which means we had a long layover and got home 3.5 hours late. Shuttle to parking stopped at 10pm, so we had to pay for an Uber to the parking lot and got charged an extra day of parking since it was after midnight. Not the best experience. Long day!

Was fine, delayed and feels like southwest is always late

I don't know why flying out of Sarasota requires two plane changes.

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

The flight was smooth. The Southwest experience has degraded overall, but this one was okay.

No gluten free snacks. Seats felt worn or bare bones even though it was a new 737 MAX 8.

One major problem that was very unprofessional and uncalled for. Plane landed and we had to wait 20 minutes to get off the plane since they were waiting for someone to come to the gate to drive the jetway. Southwest couldn't have someone available and waiting for the plane to land? Is there only one person in Hobby airport who knows to drive the jetway? Was he at lunch? In the bar? Uncomfortable and uncalled for!

The checking experience in Orlando was terrible, almost missed the flight. Too many travelers and Southwest completely understaffed.

I'm glad it wasn't only 75% full because I could get a good seat

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

St. Louis (STL)
Des Moines (DSM)