STL - DSM

$80 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$159
American Airlines
Mon 1/19Fri 1/23
STL - DSM • 1 stop
Cheapest non-stop
$240
Southwest
Wed 2/4Wed 2/11
STL - DSM • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Mon, Jan 19 - Fri, Jan 23
American Airlines Logo
6:00 am - 10:50 am
STL
-
DSM
4h 50m1 stop
American Airlines Logo
4:00 pm - 10:59 pm
DSM
-
STL
6h 59m1 stop
$159American Airlines
Wed, Jan 28 - Tue, Feb 3
Delta Logo
6:35 am - 3:41 pm
STL
-
DSM
9h 06m2 stops
Delta Logo
10:30 am - 4:45 pm
DSM
-
STL
6h 15m1 stop
$164Delta
Mon, Jan 19 - Tue, Jan 20
Delta Logo
5:25 pm - 9:24 pm
STL
-
DSM
3h 59m1 stop
Delta Logo
5:16 pm - 11:37 pm
DSM
-
STL
6h 21m1 stop
$189Delta
Mon, Jan 19 - Fri, Jan 23
Delta Logo
5:25 pm - 9:24 pm
STL
-
DSM
3h 59m1 stop
Delta Logo
10:59 am - 8:43 pm
DSM
-
STL
9h 44m2 stops
$194Delta
Tue, Jan 20 - Wed, Jan 21
American Airlines Logo
11:55 am - 5:06 pm
STL
-
DSM
5h 11m1 stop
American Airlines Logo
4:25 pm - 11:12 pm
DSM
-
STL
6h 47m1 stop
$219American Airlines
Wed, Feb 4 - Wed, Feb 11
Southwest Logo
8:00 pm - 9:10 pm
STL
-
DSM
1h 10mnonstop
Southwest Logo
3:20 pm - 4:35 pm
DSM
-
STL
1h 15mnonstop
$240Southwest
Wed, Feb 4 - Wed, Feb 11
Southwest Logo
2:35 pm - 7:20 pm
STL
-
DSM
4h 45m1 stop
Southwest Logo
3:20 pm - 4:35 pm
DSM
-
STL
1h 15mnonstop
$243Southwest
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
2:45 pm - 8:07 pm
STL
-
DSM
5h 22m1 stop
United Airlines Logo
8:00 am - 12:21 pm
DSM
-
STL
4h 21m1 stop
$279United Airlines
Wed, Apr 1 - Fri, Apr 3
Delta Logo
6:29 am - 10:22 am
STL
-
DSM
3h 53m1 stop
Delta Logo
10:28 am - 4:32 pm
DSM
-
STL
6h 04m1 stop
$287Delta
Fri, Apr 10 - Sun, Apr 12
United Airlines Logo
9:10 am - 2:25 pm
STL
-
DSM
5h 15m1 stop
United Airlines Logo
3:21 pm - 9:08 pm
DSM
-
STL
5h 47m1 stop
$329United Airlines
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Thursday is the cheapest day to fly on average and Sunday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Wednesday, with Sunday being the most expensive.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $415, prices are generally cheapest when you fly direct.

Find deals

Good to know

Low seasonJune
Cheapest flight$80
Best time to beat the crowds with an average 40% drop in price.
Most popular time to fly and prices are also 28% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 3 days, the lowest price for a flight from St. Louis to Des Moines was $80 for a one-way ticket and $159 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and JetBlue offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Boeing 737-800 Passenger/BBJ2 (winglets) is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • On which days can I fly direct from St. Louis to Des Moines?

    There are nonstop flights from St. Louis to Des Moines on a daily basis.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from St. Louis to Des Moines?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Lambert-St Louis to Des Moines.
Find which airlines fly direct from Lambert-St Louis Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to Des Moines

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Des Moines to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4248 reviews
8.0Comfort
8.1Boarding
7.5Entertainment
7.0Food
8.6Crew
Airline reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

2.0 MediocreMatthew, Jan 2026
DAL - SAN
Read more Southwest reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Flight was fine other than there was a gate change that I was not notified of. By chance I happened to check my phone and saw the change, otherwise, we would have missed our connecting flight.

Haven’t flown on SW in years. Flight was on time departing and arriving. Served vegan butter onion flavored pretzels which were bad. Coke served was in a tiny paper cup. Crew was not engaging. Felt like they were going through the motions. Old plane, tight seats and no leg room.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Okay, not wonderful. Short flight. Wi-fi didn't work properly. Stuck waiting for a gate to open upon arrival for 20 or so minutes.

They sent a notice that they were boarding an hour early. We had to leave the club and run to the gate. They said sorry, that came from corporate and was a mistake. They did not have enough seating because the flight before it had not taken off on time. They moved our gate and delayed it for an hour.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

St. Louis (STL)
Des Moines (DSM)