STL - DSM

$119 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$237
Delta
Thu 5/7Tue 5/12
STL - DSM • 1 stop
Cheapest one-way
$119
Typical prices: $164-$195
Delta
Fri 5/1
STL - DSM • 1 stop
Top airlines
Delta
Cheapest • from $237 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Minneapolis (MSP)
Cheapest • Avg $196 (round-trip)
Minneapolis (MSP)
Shortest trip • 3h 40m (one-way)
Insights
Insights
Insights
Insights
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We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Thu, May 7 - Tue, May 12
Delta Logo
6:21 am - 12:24 pm
STL
-
DSM
6h 03m
1 stop
Delta Logo
10:56 am - 4:46 pm
DSM
-
STL
5h 50m
1 stop
$237Delta
Thu, Apr 2 - Thu, Apr 9
Delta Logo
6:00 am - 10:48 am
STL
-
DSM
4h 48m
1 stop
Delta Logo
6:15 am - 12:58 pm
DSM
-
STL
6h 43m
1 stop
$241Delta
Thu, May 7 - Tue, May 12
Delta Logo
6:00 am - 11:08 am
STL
-
DSM
5h 08m
1 stop
Delta Logo
7:01 am - 1:10 pm
DSM
-
STL
6h 09m
2 stops
$242Delta
Mon, Apr 6 - Wed, Apr 8
United Airlines Logo
7:45 am - 12:29 pm
STL
-
DSM
4h 44m
1 stop
United Airlines Logo
3:27 pm - 9:13 pm
DSM
-
STL
5h 46m
1 stop
$257United Airlines
Mon, Apr 6 - Wed, Apr 8
Southwest Logo
2:30 pm - 10:20 pm
STL
-
DSM
7h 50m
1 stop
Southwest Logo
6:55 am - 1:00 pm
DSM
-
STL
6h 05m
2 stops
$262Southwest
Sat, Apr 11 - Tue, Apr 14
Southwest Logo
6:10 am - 1:30 pm
STL
-
DSM
7h 20m
2 stops
Southwest Logo
5:30 am - 12:50 pm
DSM
-
STL
7h 20m
2 stops
$267Southwest
Tue, Mar 31 - Sat, Apr 4
American Airlines Logo
9:59 am - 6:28 pm
STL
-
DSM
8h 29m
1 stop
American Airlines Logo
11:26 am - 5:13 pm
DSM
-
STL
5h 47m
1 stop
$270American Airlines
Wed, Apr 15 - Thu, Apr 16
Delta Logo
7:25 am - 1:55 pm
STL
-
DSM
6h 30m
1 stop
Delta Logo
5:45 am - 10:34 am
DSM
-
STL
4h 49m
1 stop
$275Delta
Thu, May 28 - Sat, May 30
Delta Logo
6:21 am - 12:24 pm
STL
-
DSM
6h 03m
1 stop
Delta Logo
10:56 am - 4:46 pm
DSM
-
STL
5h 50m
1 stop
$277Delta
Wed, Apr 15 - Thu, Apr 16
Southwest Logo
2:30 pm - 10:10 pm
STL
-
DSM
7h 40m
2 stops
Southwest Logo
4:20 pm - 10:45 pm
DSM
-
STL
6h 25m
1 stop
$280Southwest
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Wednesday, with Sunday being the most expensive.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $318 on average.

Find deals

Good to know

Low seasonMarch
Cheapest flight$119
Best time to beat the crowds with an average 46% drop in price.
Most popular time to fly and prices are also 34% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 3 days, the lowest price for a flight from St. Louis to Des Moines was $119 for a one-way ticket and $237 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and JetBlue offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $194 or less one-way.

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4311 reviews
8.1Boarding
7.5Entertainment
8.0Comfort
8.6Crew
7.0Food
Airline reviews

I realize they are still working out kinks with the new boarding process, but by the time I boarded in group 5, most of the bins were full. All airlines should better enforce small bags and jackets going under the seats until everyone has boarded.

8.0 ExcellentAnonymous, Mar 2026
MCO - IND
Read more Southwest reviews

I realize they are still working out kinks with the new boarding process, but by the time I boarded in group 5, most of the bins were full. All airlines should better enforce small bags and jackets going under the seats until everyone has boarded.

WiFi was not working and didn’t have a beverage service

Snacks are always pretzels. Why can't you also offer peanuts ?

Flight boarded late after announcing on time boarding. Flight arrived only a little late despite late departure. Had trouble connecting to WiFi

Mediocre. Boarding is now unpleasant. The employees, once friendly and nice, are now regularly speaking sternly to passengers, badgering them to do things right so they can take off on time and gate check bags because they don't have enough overhead bin space. The pretzel snack was crushed flat and broken into even smaller pieces, which happens frequently lately. Drink service was suspended before they reached my row.

The last 3 flights between BWI and BDL canceled the beverage service mid- way. Just say up front that the fight is too short. Thanks!

It was canceled. Supposedly weather. But there was no snow in Baltimore. At least we found out before driving to airport

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

The Southwest experience has definitely taken a dive from its early days. You can no longer deferentiate from other airlines. Air travel is too expensive. Southwest is no longer budget friendly. They have lost me as a loyal customer.

Flight was hours late, unable to sit next to spouse, I have had so much better experiences. Substantially better, only saving grace was that it was a short flight.

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

St. Louis (STL)
Des Moines (DSM)