STL - DSM

$49 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Flights Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Thu, Aug 7 - Mon, Aug 11
Southwest Logo
9:40 pm - 10:50 pmSTL-DSM
1h 10mnonstop
Southwest Logo
5:30 pm - 6:35 pmDSM-STL
1h 05mnonstop
$193Southwest
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Wed, Jul 30 - Wed, Aug 6
American Airlines Logo
6:00 am - 9:33 amSTL-DSM
3h 33m1 stop
American Airlines Logo
5:29 pm - 11:05 pmDSM-STL
5h 36m1 stop
$198American Airlines
Find Deal
Thu, Aug 7 - Mon, Aug 11
Southwest Logo
9:40 pm - 10:50 pmSTL-DSM
1h 10mnonstop
Southwest Logo
1:55 pm - 11:55 pmDSM-STL
10h 00m1 stop
$220Southwest
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Tue, Jul 29 - Tue, Aug 5
American Airlines Logo
6:00 am - 9:33 amSTL-DSM
3h 33m1 stop
American Airlines Logo
5:00 am - 11:51 pmDSM-STL
18h 51m1 stop
$227American Airlines
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Tue, Jul 29 - Tue, Aug 5
Delta Logo
2:15 pm - 8:57 pmSTL-DSM
6h 42m2 stops
Delta Logo
6:40 pm - 11:53 pmDSM-STL
5h 13m1 stop
$239Delta
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Thu, Aug 7 - Mon, Aug 11
American Airlines Logo
5:32 pm - 11:03 pmSTL-DSM
5h 31m1 stop
American Airlines Logo
3:20 pm - 8:18 pmDSM-STL
4h 58m1 stop
$256American Airlines
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Thu, Jul 10 - Fri, Jul 11
Logo
9:50 am - 10:38 pmSTL-DSM
12h 48m2 stops
Logo
2:00 pm - 2:39 pmDSM-STL
24h 39m2 stops
$311
Find Deal
Wed, Jul 30 - Wed, Aug 6
Delta Logo
6:40 am - 5:09 pmSTL-DSM
10h 29m2 stops
Delta Logo
6:05 am - 1:21 pmDSM-STL
7h 16m1 stop
$348Delta
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Wed, Jul 2 - Sun, Jul 6
United Airlines Logo
10:00 am - 2:41 pmSTL-DSM
4h 41m1 stop
United Airlines Logo
6:50 pm - 10:45 pmDSM-STL
3h 55m1 stop
$362United Airlines
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Tue, Aug 12 - Wed, Aug 13
United Airlines Logo
8:00 am - 2:41 pmSTL-DSM
6h 41m1 stop
United Airlines Logo
6:50 pm - 10:45 pmDSM-STL
3h 55m1 stop
$477United Airlines
Find Deal
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KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Saturday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Tuesday, with Saturday being the most expensive.

What is the cheapest month to fly from St. Louis to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Des Moines is June, where tickets cost $213 (return) on average. On the other hand, the most expensive months are March and August, where the average cost of round-trip tickets is $472 and $470 respectively.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $365 on average.

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Good to know

Low seasonMarch
High seasonApril
Cheapest flight$49
Best time to beat the crowds but there is an average 31% increase in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 3 days, the lowest price for a flight from St. Louis to Des Moines was $49 for a one-way ticket and $193 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Boeing 737-700 Passenger/BBJ1 (winglets) is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • On which days can I fly direct from St. Louis to Des Moines?

    There are nonstop flights from St. Louis to Des Moines on a daily basis.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $184 or less one-way.

Prefer to fly direct from St. Louis to Des Moines?

Find which airlines fly direct from Lambert-St Louis Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to Des Moines

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Des Moines to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights
See more direct flights

Top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4285 reviews
8.0Comfort
7.1Food
8.2Boarding
8.6Crew
7.6Entertainment
Airline reviews

Southwest is Southwest. No frills. If you're luck enough to get a happy crew (we did), then it makes for a nicer flight.

10.0 ExcellentMichael, Jun 2025SMF - SEA
Read more Southwest reviews

Southwest is Southwest. No frills. If you're luck enough to get a happy crew (we did), then it makes for a nicer flight.

Southwest is typically delayed, and it gets wearisome. It is no longer a discount airline and you get way less than you pay for when it comes to comfort and Ce.

We sat on the plane on the tarmac for 4 hours.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

Flight crew and cabin crew were great. I had to rearrange flights because my original flight was 3hrs delayed for weather, the rub is the flight I moved to boarded on time then we sat at the gate for 2 hours because scheduling stole our first officer for another flight, TWICE. Then our actual FO was an hour delayed. To make it worse my original flight went from a 3 hour delay to departing 15min EARLY. Just poor scheduling operations all around.

Bring back peanuts Take our drink orders when were all seated, especially after you switch to assigned seating.

Staff was far less than helpful at all times. Departure and arrival times mean nothing to Southwest. Extremely disappointed, will never fly with them again, and I’ll be sure to share my experience with all.

It is southwest seat was ok. Not the most comfortable seat

I’ve always loved Southwest. No issues at all. I was flying standby and the gate agent was extremely friendly and helpful. Boarding was smooth and I was able to get a window seat in the emergency exit row. Crew was fantastic! They were very professional and accommodating. We had to divert from our destination due to weather but the flight crew kept everyone at ease and informed us of all pertinent information. Excellent flight

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

St. Louis (STL)
Des Moines (DSM)

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