STL - DSM

$68 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Tue, Mar 10 - Wed, Mar 11
Delta Logo
6:30 am - 10:22 amSTL-DSM
3h 52m1 stop
Delta Logo
10:15 am - 4:55 pmDSM-STL
6h 40m1 stop
$260Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11
Delta Logo
10:00 am - 4:30 pmSTL-DSM
6h 30m1 stop
Delta Logo
10:15 am - 6:04 pmDSM-STL
7h 49m2 stops
$265Delta
Find Deal
Wed, Nov 5 - Sun, Nov 9
Multiple Airlines Logo
7:45 pm - 1:56 pmSTL-DSM
18h 11m1 stop
Multiple Airlines Logo
9:03 pm - 6:36 pmDSM-STL
21h 33m2 stops
$270Multiple Airlines
Find Deal
Wed, Nov 5 - Sun, Nov 9
Frontier Logo
7:45 pm - 1:56 pmSTL-DSM
18h 11m1 stop
Frontier Logo
2:32 pm - 9:07 amDSM-STL
18h 35m1 stop
$304Frontier
Find Deal
Thu, Nov 6 - Sun, Nov 9
Frontier Logo
7:45 pm - 1:47 pmSTL-DSM
18h 02m1 stop
Frontier Logo
2:32 pm - 9:07 amDSM-STL
18h 35m1 stop
$317Frontier
Find Deal
Thu, Nov 6 - Sun, Nov 9
Multiple Airlines Logo
7:45 pm - 1:47 pmSTL-DSM
18h 02m1 stop
Multiple Airlines Logo
9:03 pm - 1:17 pmDSM-STL
16h 14m2 stops
$324Multiple Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
Southwest Logo
1:45 pm - 7:55 pmSTL-DSM
6h 10m1 stop
Southwest Logo
6:50 pm - 7:55 pmDSM-STL
1h 05mnonstop
$329Southwest
Find Deal
Wed, Nov 19 - Wed, Nov 26
American Airlines Logo
9:36 am - 2:56 pmSTL-DSM
5h 20m1 stop
American Airlines Logo
6:56 pm - 11:56 pmDSM-STL
5h 00m1 stop
$340American Airlines
Find Deal
Tue, Nov 25 - Mon, Dec 1
Southwest Logo
9:50 am - 11:00 amSTL-DSM
1h 10mnonstop
Southwest Logo
6:35 am - 12:20 pmDSM-STL
5h 45m1 stop
$350Southwest
Find Deal
Tue, Nov 25 - Mon, Dec 1
American Airlines Logo
7:00 am - 2:51 pmSTL-DSM
7h 51m1 stop
American Airlines Logo
3:31 pm - 10:34 pmDSM-STL
7h 03m1 stop
$369American Airlines
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $260 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
June
Cheapest • 36% price drop
April
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$260
Overall average: $472
Delta
Tue 3/10Wed 3/11
STL - DSM • 1 stop
Cheapest non-stop
$329
Typical prices: $77-$383
Southwest
Wed 11/19Wed 11/26
STL - DSM • Non-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Saturday is the cheapest day to fly on average and Friday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Tuesday, with Friday being the most expensive.

What is the cheapest month to fly from St. Louis to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Des Moines is June, where tickets cost $213 (return) on average. On the other hand, the most expensive months are July and March, where the average cost of round-trip tickets is $663 and $472 respectively.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $239 on average.

Good to know

Low seasonJuly
Cheapest flight$75
Best time to beat the crowds but there is an average 100% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 3 days, the lowest price for a flight from St. Louis to Des Moines was $75 for a one-way ticket and $260 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • On which days can I fly direct from St. Louis to Des Moines?

    There are nonstop flights from St. Louis to Des Moines on a daily basis.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $171 or less round-trip.

Prefer to fly direct from St. Louis to Des Moines?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Lambert-St Louis to Des Moines.
Find which airlines fly direct from Lambert-St Louis Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to Des Moines

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Des Moines to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4235 reviews
8.1Boarding
8.0Comfort
7.0Food
7.5Entertainment
8.6Crew
Airline reviews

Sacrament staff are always polite and helpful. Airport is easy to maneuver and boarding is straightforward.

10.0 ExcellentStacy, Oct 2025SMF - DEN
Read more Southwest reviews

Sacrament staff are always polite and helpful. Airport is easy to maneuver and boarding is straightforward.

Great flight. Outstanding Service. Southwest was able to put us on a direct flight to Denver when the connection could have been affected by a later arrival to Baltimore. The direct flight was less expensive that the flight with the connection in Baltimore.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

Boarded on time but once we were ready for take off, the crew determined that, although every seat was taken, somehow someone was on the wrong flight. Delay, delay delay, announcements and ended up with one person checking EVERY ID against their passenger Manifest only to figure out it was a "clerical error." We departed 54 minutes late causing me to run in the St. Louis Airport to make my connection and lose the priority boarding spot I had paid for. Unnecessary delay.

I was re-booked onto another flight because my original flight was delayed and I would have missed my connector. I ended up in the “C” group after paying extra to be in the “A “ group on the original flight. At least if you’re going to re-book people, re-book them into the same group.

Flight was delayed due to plane not passing inspection And one of the crew had to time out and we had to wait for another one A 3 hour delay

mandatory demand customer to check their carry on because not enough people check bags.

Connecting flight is on time and boarding was a breeze!

Excellent. Would encourage Southwest to keep current boarding procedures with free style seating. Makes for a fantastic experience

As always, the entire Southwest experience was perfect. Purchasing the tickets on the Southwest web site was effortless, departure and arrival gates were spotless and comfortable, plane was clean and comfortable, crew was excellent and flight was on time. Wheelchair service in Las Vegas at departure was somewhat chaotic and disjointed, but I am not sure if that was Southwest problem, airport problem or combination.

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

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