STL - DSM

$39 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Thu, Sep 11 - Thu, Sep 18
Southwest Logo
9:40 pm - 10:50 pmSTL-DSM
1h 10mnonstop
Southwest Logo
6:00 am - 7:05 amDSM-STL
1h 05mnonstop
$77Southwest
Find Deal
Sat, Sep 6 - Sat, Sep 13
Southwest Logo
2:05 pm - 8:20 pmSTL-DSM
6h 15m2 stops
Southwest Logo
8:35 am - 9:40 amDSM-STL
1h 05mnonstop
$92Southwest
Find Deal
Thu, Sep 11 - Tue, Sep 16
Delta Logo
3:40 pm - 10:37 pmSTL-DSM
6h 57m1 stop
Delta Logo
11:25 am - 4:05 pmDSM-STL
4h 40m1 stop
$177Delta
Find Deal
Sat, Oct 25 - Sun, Oct 26
American Airlines Logo
9:58 am - 4:17 pmSTL-DSM
6h 19m1 stop
American Airlines Logo
7:30 am - 1:44 pmDSM-STL
6h 14m1 stop
$234American Airlines
Find Deal
Sat, Sep 6 - Sat, Sep 13
American Airlines Logo
9:56 am - 3:33 pmSTL-DSM
5h 37m1 stop
American Airlines Logo
4:09 pm - 10:50 pmDSM-STL
6h 41m1 stop
$245American Airlines
Find Deal
Thu, Sep 11 - Tue, Sep 16
United Airlines Logo
5:15 am - 10:46 amSTL-DSM
5h 31m1 stop
United Airlines Logo
1:10 pm - 11:44 pmDSM-STL
10h 34m2 stops
$298United Airlines
Find Deal
Tue, Sep 9 - Thu, Sep 11
Delta Logo
6:40 am - 5:12 pmSTL-DSM
10h 32m2 stops
Delta Logo
6:30 pm - 11:24 pmDSM-STL
4h 54m1 stop
$388Delta
Find Deal
Thu, Sep 11 - Thu, Sep 18
 Logo
10:35 am - 2:40 pmSTL-DSM
28h 05m3 stops
 Logo
8:00 am - 11:27 amDSM-STL
27h 27m3 stops
Sat, Aug 30 - Wed, Sep 3
United Airlines Logo
6:35 am - 10:39 amSTL-DSM
4h 04m1 stop
United Airlines Logo
11:35 am - 6:23 pmDSM-STL
6h 48m1 stop
$453United Airlines
Find Deal
Thu, Sep 11 - Thu, Sep 18
 Logo
10:35 am - 2:40 pmSTL-DSM
28h 05m3 stops
 Logo
3:42 pm - 11:27 amDSM-STL
19h 45m2 stops
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from St. Louis to Des Moines?

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Saturday is the cheapest day to fly on average and Friday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Tuesday, with Saturday being the most expensive.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $159 on average.

Good to know

Low seasonJune
Cheapest flight$39
Best time to beat the crowds with an average 37% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 3 days, the lowest price for a flight from St. Louis to Des Moines was $39 for a one-way ticket and $77 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • On which days can I fly direct from St. Louis to Des Moines?

    There are nonstop flights from St. Louis to Des Moines on a daily basis.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $381 or less round-trip.

Prefer to fly direct from St. Louis to Des Moines?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Lambert-St Louis to Des Moines.
Find which airlines fly direct from Lambert-St Louis Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to Des Moines

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Des Moines to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4244 reviews
8.0Comfort
7.5Entertainment
8.1Boarding
7.0Food
8.6Crew
Airline reviews

Southwest's seats are the least comfortable I have ever sat in.

4.0 OkayDavid, Aug 2025DTW - STL
Read more Southwest reviews

Southwest's seats are the least comfortable I have ever sat in.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

Southwest like most American domestic airlines, is a mediocre airline. But it is among the cheapest. Oh well.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

Other than a bit of a delay, everything was good. Again, the boarding process and picking seats is the only thing I don't enjoy.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

southwest just starting charging for luggage. hadnt realized it until it was too late. now out $70 when i couldve bought a carry on if i wouldve known. free bags was one of the only reasons i chose southwest over another airline (the other being no assigned seats, which is apparently also being changed). stupid business decision. wont be flying southwest anymore.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

WiFi did not work. For as outrageous as these flights cost, when they’re advertised with certain services/ features they should be in working order

Everything you need to know for your flight from St. Louis to Des Moines

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