STL - DSM

$68 Find Cheap Flights from St. Louis to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Des Moines departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$183
Delta
Tue 1/6Wed 1/7
STL - DSM • 1 stop
Cheapest non-stop
$206
Southwest
Wed 2/4Thu 2/5
STL - DSM • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Des Moines (STL-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Des Moines

Tue, Jan 6 - Wed, Jan 7
Delta Logo
5:25 pm - 9:24 pmSTL-DSM
3h 59m1 stop
Delta Logo
10:59 am - 4:45 pmDSM-STL
5h 46m1 stop
$183Delta
Find Deal
Tue, Jan 6 - Wed, Jan 7
Delta Logo
6:35 am - 3:41 pmSTL-DSM
9h 06m2 stops
Delta Logo
5:35 am - 11:05 amDSM-STL
5h 30m1 stop
$188Delta
Find Deal
Tue, Jan 6 - Wed, Jan 7
Delta Logo
6:35 am - 3:41 pmSTL-DSM
9h 06m2 stops
Delta Logo
6:24 am - 2:48 pmDSM-STL
8h 24m2 stops
$193Delta
Find Deal
Wed, Feb 4 - Thu, Feb 5
Southwest Logo
10:15 am - 11:25 amSTL-DSM
1h 10mnonstop
Southwest Logo
5:20 am - 6:40 amDSM-STL
1h 20mnonstop
$206Southwest
Find Deal
Wed, Feb 4 - Thu, Feb 5
Southwest Logo
2:35 pm - 7:20 pmSTL-DSM
4h 45m1 stop
Southwest Logo
4:40 pm - 5:50 pmDSM-STL
1h 10mnonstop
$216Southwest
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Tue, Jan 6 - Wed, Jan 7
Delta Logo
9:59 am - 8:54 pmSTL-DSM
10h 55m2 stops
Delta Logo
12:04 pm - 11:39 pmDSM-STL
11h 35m2 stops
$251Delta
Find Deal
Wed, Dec 31 - Mon, Jan 5
Southwest Logo
10:15 am - 11:25 amSTL-DSM
1h 10mnonstop
Southwest Logo
5:45 am - 7:05 amDSM-STL
1h 20mnonstop
$272Southwest
Find Deal
Thu, Dec 11 - Sun, Dec 14
Southwest Logo
8:25 pm - 9:35 pmSTL-DSM
1h 10mnonstop
Southwest Logo
8:00 am - 2:25 pmDSM-STL
6h 25m1 stop
$283Southwest
Find Deal
Thu, Dec 11 - Sun, Dec 14
Delta Logo
6:00 am - 10:21 amSTL-DSM
4h 21m1 stop
Delta Logo
5:34 am - 10:45 amDSM-STL
5h 11m1 stop
$288Delta
Find Deal
Thu, Dec 11 - Sun, Dec 14
Delta Logo
6:00 am - 10:38 amSTL-DSM
4h 38m1 stop
Delta Logo
6:50 am - 1:53 pmDSM-STL
7h 03m2 stops
$293Delta
Find Deal
Booking Insights

KAYAK's insights & trends for St. Louis to Des Moines flights

Get data-powered insights and trends into flights from St. Louis to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Des Moines?

The average price of all round-trip flights from St. Louis to Des Moines clicked on KAYAK for each day over the last 12 months.

For St. Louis to Des Moines, Thursday is the cheapest day to fly on average and Friday is the most expensive. Flying from Des Moines back to St. Louis, the best deals are generally found on Tuesday, with Saturday being the most expensive.

Can I save money by flying with a layover from St. Louis to Des Moines?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $381, prices are generally cheapest when you fly direct.

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Good to know

Low seasonJune
Cheapest flight$68
Best time to beat the crowds with an average 40% drop in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from St. Louis to Des Moines

When to book flights from St. Louis to Des Moines

Are your dates flexible? Find out the best times to travel from St. Louis to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Des Moines

  • What is the cheapest flight from St. Louis to Des Moines?

    In the last 3 days, the lowest price for a flight from St. Louis to Des Moines was $68 for a one-way ticket and $183 for a round-trip.

  • Do I need a passport to fly between St. Louis and Des Moines?

    A passport is not required to fly from St. Louis to Des Moines.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to Des Moines?

    American Airlines, Alaska Airlines, and JetBlue offer inflight Wi-Fi service on the St. Louis to Des Moines flight route.

  • Which aircraft models fly most regularly from St. Louis to Des Moines?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the St. Louis to Des Moines flight route.

  • On which days can I fly direct from St. Louis to Des Moines?

    There are nonstop flights from St. Louis to Des Moines on a daily basis.

  • How does KAYAK find such low prices on flights from St. Louis to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Des Moines

  • Looking for a cheap flight? 25% of our users found flights on this route for $501 or less round-trip.

Prefer to fly direct from St. Louis to Des Moines?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Lambert-St Louis to Des Moines.
Find which airlines fly direct from Lambert-St Louis Airport to Des Moines Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to Des Moines

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Des Moines to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top airline flying from St. Louis to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4252 reviews
8.0Comfort
8.6Crew
8.1Boarding
7.0Food
7.5Entertainment
Airline reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

10.0 ExcellentIlevba, Nov 2025DCA - DAL
Read more Southwest reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

It was rough. The staff was unprofessional, the choice of on board drinks terrible, it was cramped in space at every airport, they always ran out of overhead bin space so they pressured people to check bags for free or we couldn’t leave on the plane— so I did check my bag to help, and they nearly lost my bag. My bag did not arrive on the luggage belt, another man on my flight and I had to waste our time going to the baggage office to search for our bags. I would only fly southwest again if it was my last choice. Also, my flights were consistently delayed over and over again— at one point they straight up told us we were waiting for the pilot to arrive.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

Everything a cheap airline should be at normal airline rates.

Plane crashed into a bus or some other vehicle on the ground while pulling out of the gate. No injuries, but wing tip was damaged and returned to gate for “maintenance issues” and we departed 5 hours later because the plane went out of service and new plane was flown in from a nearby airport, Midway.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Full cans of soda would be nice. A choice between two snacks would be appreciated.

Tried watching free movie and it kept freezing so I couldn’t finish.

Everything you need to know for your flight from St. Louis to Des Moines

Information on your arrival and departure airports

St. Louis (STL)
Des Moines (DSM)