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$111 Find Cheap Flights from Missouri to Des Moines - Compare and Save

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1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Missouri to Des Moines

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Missouri to Des Moines

Tue, Dec 8 - Tue, Dec 8
Southwest Logo
8:25 am - 2:15 pmSTL  Lambert-St Louis-DSM Des Moines
5h 50m1 stop Denver Intl
Southwest Logo
3:25 pm - 10:00 pmDSM  Des Moines-STL Lambert-St Louis
6h 35m1 stop Chicago Midway
$237Southwest
Mon, Nov 23 - Thu, Nov 26
Delta Logo
5:22 pm - 9:13 pmSTL  Lambert-St Louis-DSM Des Moines
3h 51m1 stop Minneapolis St Paul
Delta Logo
2:48 pm - 7:31 pmDSM  Des Moines-STL Lambert-St Louis
4h 43m1 stop Minneapolis St Paul
$237Delta
Wed, Nov 25 - Wed, Dec 2
United Airlines Logo
1:08 pm - 7:16 pmSTL  Lambert-St Louis-DSM Des Moines
6h 08m1 stop Chicago O'Hare Intl
United Airlines Logo
9:30 am - 2:41 pmDSM  Des Moines-STL Lambert-St Louis
5h 11m1 stop Chicago O'Hare Intl
$237United Airlines
Thu, Nov 26 - Thu, Nov 26
Delta Logo
6:13 am - 10:37 amSTL  Lambert-St Louis-DSM Des Moines
4h 24m1 stop Minneapolis St Paul
Delta Logo
2:48 pm - 7:31 pmDSM  Des Moines-STL Lambert-St Louis
4h 43m1 stop Minneapolis St Paul
$237Delta
Tue, Nov 24 - Thu, Nov 26
Delta Logo
6:13 am - 10:19 amSTL  Lambert-St Louis-DSM Des Moines
4h 06m1 stop Minneapolis St Paul
Delta Logo
6:45 am - 11:50 amDSM  Des Moines-STL Lambert-St Louis
5h 05m1 stop Minneapolis St Paul
$237Delta
Wed, Nov 25 - Wed, Dec 2
Southwest Logo
1:40 pm - 11:35 pmSTL  Lambert-St Louis-DSM Des Moines
9h 55m1 stop Chicago Midway
Southwest Logo
6:00 am - 1:45 pmDSM  Des Moines-STL Lambert-St Louis
7h 45m2 stops Chicago Midway Atlanta Hartsfield-Jackson
$248Southwest
Sat, Dec 12 - Sun, Dec 13
Southwest Logo
4:20 pm - 7:40 pmSTL  Lambert-St Louis-DSM Des Moines
3h 20m1 stop Chicago Midway
Southwest Logo
5:25 am - 10:05 amDSM  Des Moines-STL Lambert-St Louis
4h 40m1 stop Chicago Midway
$292Southwest
Wed, Nov 25 - Mon, Nov 30
Multiple Airlines Logo
3:04 pm - 7:33 pmSTL  Lambert-St Louis-DSM Des Moines
28h 29m1 stop Denver Intl
Multiple Airlines Logo
9:39 pm - 11:06 amDSM  Des Moines-STL Lambert-St Louis
37h 27m2 stops Las Vegas Harry Reid Intl Denver Intl
$301Multiple Airlines
Mon, Nov 23 - Sun, Nov 29
United Airlines Logo
1:08 pm - 5:28 pmSTL  Lambert-St Louis-DSM Des Moines
4h 20m1 stop Chicago O'Hare Intl
United Airlines Logo
6:45 pm - 11:24 pmDSM  Des Moines-STL Lambert-St Louis
4h 39m1 stop Chicago O'Hare Intl
$308United Airlines
Sat, Nov 21 - Thu, Nov 26
Frontier Logo
5:15 pm - 7:33 pmSTL  Lambert-St Louis-DSM Des Moines
26h 18m2 stops Las Vegas Harry Reid Intl Denver Intl
Frontier Logo
8:28 pm - 11:03 amDSM  Des Moines-STL Lambert-St Louis
14h 35m1 stop Denver Intl
$337Frontier
Useful Info

Good to know

Low season

January

Cheapest flight

$111
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from St. Louis to Des Moines

FAQs for booking flights from Missouri to Des Moines

  • How does KAYAK find such low prices on flights from Missouri to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missouri to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Missouri with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Altoona
Urbandale
Newton
Osceola
Johnston
Grinnell
Carlisle

More options for your flight to Des Moines