$165 Find Cheap Flights from Louisville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South America departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Louisville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$399
Bogotá
Bogotá1 stop$329
Santiago
Santiago2 stops$750
Quito
Quito2 stops$608
Guayaquil
Guayaquil1 stop$646
Montevideo
Montevideo2 stops$970
Barranquilla
Barranquilla2 stops$409
Lima
Lima1 stop$399
Bogotá
Bogotá1 stop$329
Santiago
Santiago2 stops$750
Quito
Quito2 stops$608
Guayaquil
Guayaquil1 stop$646
Montevideo
Montevideo2 stops$970
Barranquilla
Barranquilla2 stops$409

Book Cheap Louisville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South America

Mon, Feb 2 - Mon, Feb 9
Multiple Airlines Logo
6:54 pm - 10:35 pm
SDF
-
LIM
27h 41m1 stop
Multiple Airlines Logo
11:33 pm - 2:41 pm
LIM
-
SDF
15h 08m1 stop
$399Multiple Airlines
Mon, Jan 26 - Mon, Feb 9
Spirit Airlines Logo
1:55 pm - 2:44 pm
SDF
-
BAQ
24h 49m2 stops
Spirit Airlines Logo
3:39 pm - 2:41 pm
BAQ
-
SDF
23h 02m1 stop
$409Spirit Airlines
Mon, Feb 2 - Thu, Feb 5
LATAM Airlines Logo
7:00 am - 7:30 pm
SDF
-
BOG
12h 30m1 stop
LATAM Airlines Logo
9:00 am - 5:01 pm
BOG
-
SDF
8h 01m1 stop
$533LATAM Airlines
Mon, Feb 2 - Thu, Feb 5
LATAM Airlines Logo
7:00 am - 7:30 pm
SDF
-
BOG
12h 30m1 stop
LATAM Airlines Logo
10:55 am - 11:50 pm
BOG
-
SDF
12h 55m2 stops
$538LATAM Airlines
Tue, Feb 3 - Mon, Feb 9
United Airlines Logo
9:15 am - 10:35 pm
SDF
-
BOG
13h 20m1 stop
United Airlines Logo
1:30 am - 7:54 pm
BOG
-
SDF
18h 24m1 stop
$553United Airlines
Tue, Feb 3 - Tue, Feb 10
United Airlines Logo
5:35 am - 11:05 pm
SDF
-
BOG
17h 30m2 stops
United Airlines Logo
8:15 am - 9:59 pm
BOG
-
SDF
13h 44m1 stop
$558United Airlines
Mon, Jan 26 - Mon, Feb 9
American Airlines Logo
6:00 am - 1:33 pm
SDF
-
BAQ
7h 33m1 stop
American Airlines Logo
2:33 pm - 11:59 pm
BAQ
-
SDF
9h 26m1 stop
$575American Airlines
Wed, Jan 21 - Thu, Feb 19
Delta Logo
5:35 am - 9:35 pm
SDF
-
UIO
16h 00m1 stop
Delta Logo
11:45 pm - 2:34 pm
UIO
-
SDF
14h 49m1 stop
$615Delta
Sat, Feb 14 - Wed, Feb 25
American Airlines Logo
6:01 am - 11:23 pm
SDF
-
UIO
17h 22m1 stop
American Airlines Logo
7:30 am - 11:59 pm
UIO
-
SDF
16h 29m1 stop
$651American Airlines
Sun, Feb 15 - Mon, Feb 23
Delta Logo
8:55 am - 7:20 am
SDF
-
EZE
20h 25m1 stop
Delta Logo
8:55 pm - 2:34 pm
EZE
-
SDF
19h 39m1 stop
$1,066Delta
Booking Insights

KAYAK's insights & trends for Louisville to South America flights

Get data-powered insights and trends into flights from Louisville to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Louisville and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Louisville to South America.

There are 4 airlines that fly nonstop from Louisville to South America. They are: American Airlines, LATAM Airlines, Delta and Spirit Airlines. The cheapest price of all airlines flying this route was found with Spirit Airlines at $254 for a round-trip flight to Lima (LIM). On average, Spirit Airlines offers the best prices for nonstop flights between Louisville and South America.

Which airlines provide the cheapest flights from Louisville to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Louisville to South America were found on Spirit Airlines ($409) and United Airlines ($518).

Good to know

Low seasonOctober
Cheapest flight$165
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 66% increase in price.
Flight from Louisville to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Louisville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $737 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $787.

Reviews of the top 4 airlines serving from Louisville to South America

 
Need help choosing which airline to fly with from Louisville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8018 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.9Entertainment
7.3Food
Airline reviews

Flight delays both to Detroits and return flight . The flight to Detroit was associated with mechanical difficulty

2.0 MediocreGina, Dec 2025
DTW - ELM
Read more Delta reviews

Flight delays both to Detroits and return flight . The flight to Detroit was associated with mechanical difficulty

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

Wasn't a Delta issue I don't think, but seems there was a Delta flight at each of the 2 Dallas airports at the same exact time, both to Atlanta. I was evidently booked on the one at Love Airport, but the Carey transport shuttle took me to DFW instead and I ended up missing the flight by just a few minutes. Was able to book a Southwest flight from Love Airport, but was a big loss of time and an inconvenience.

Great. I had to modify a flight. That was easy and free. Thank You

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

For whatever reason, the flight was not catered -we were told it would be a 45 minute delay waiting for catering - so no food. There were opened candy and peanuts in the seatback pocket. Flight landed early in DFW but due to the assigned gate not being available, we sat on the ground for 30 minutes waiting for the gate to open - making the flight actually arrive at the gate late.

Not great. Booked Extra seats and got nothing extra at all. It’s basically a big budget airline.

The pilot greased the landing and the crew was fantastic.

I bought wifi and most of the flight could not even use it my apps would just spin. I couldn't even listen to music. super frustrating.

delayed due to weather. Could not communicate with family since the wifi was broken

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Flight was delayed 17 hours due to aircraft issues. American did provide hotel, transportation and meals, 3 hours past boarding time, but it took us another hour to get the vouchers.

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

Flight was late and boarding was confusing because gate changed and I didn’t get a notification

The most horrible flight ever not only Spirit delayed our flight 2 hours departure time for a 1 hour flight — that I could have driven FLL to TPA and spend less time on the road —- and they did the same on the return with 2-hr delay again!!! Then to top all, the rubber like and most unconfortable seats in the industry with no leg room!!! There should be an award for these kinds of companies measuring % of returning customers!!!

The flight was cancelled and Spirit said they could not rebook me on another flight for six days. They said they couldn't do anything for another six days.

Flight was on time, Newark staff, especially Nathan, very helpful, and plane crew to RDU very good without being pushy. We arrived early, and had a gentle landing.

See my last comment for the first leg. That should’ve been in here

Horrible. Arrived at my gate at 6:37 for a 6:50 flight and was denied by staff to board. Literally watched my flight leave from the window and it didn’t take off until after 7am. Tried to talk to staff and they were rude beyond compare. Will never fly with this airline again.

Our flight got rescheduled 48 hours later, the airline didn’t pay a penny for our expenses.

We had to sit and wait for almost an hour after landing and taxiing to the gate. The jet bridge was broken so we just waited and waited and waited and it was inconvenient, hot, and unnecessary.

Flight was in time, very smooth ride and surprisingly lots of legroom in the cabin so I certainly will fly with spirit again

The seats are the most uncomfortable seats I’ve ever sat in. Don’t believe I’ll ever fly spirit again!!

Flight was canceled and instead of rescheduling at the gate we had to go out to the ticket counter. Unruly kids kicking the back of my rows chair with staff to inattentive to say something.

Everything you need to know for your flight to South America

Information on your arrival and departure airports