$319 Find Cheap Flights from Louisville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South America departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Louisville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$709
Bogotá
Bogotá2 stops$599
Santiago
Santiago2 stops$1,139
Quito
Quito1 stop$685
Barranquilla
Barranquilla1 stop$722
Montevideo
Montevideo2 stops$1,233
Lima
Lima2 stops$709
Bogotá
Bogotá2 stops$599
Santiago
Santiago2 stops$1,139
Quito
Quito1 stop$685
Barranquilla
Barranquilla1 stop$722
Montevideo
Montevideo2 stops$1,233

Book Cheap Louisville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South America

Mon, Jul 13 - Wed, Aug 5
LATAM Airlines Logo
7:05 am - 8:10 pm
SDF
-
BOG
14h 05m
2 stops
LATAM Airlines Logo
2:55 pm - 12:24 am
BOG
-
SDF
8h 29m
1 stop
$599LATAM Airlines
Wed, Jun 10 - Tue, Jun 23
Delta Logo
11:19 am - 7:15 pm
SDF
-
BOG
8h 56m
1 stop
Delta Logo
5:00 am - 12:32 am
BOG
-
SDF
18h 32m
2 stops
$642Delta
Wed, Jun 10 - Tue, Jun 23
Delta Logo
8:10 am - 8:10 pm
SDF
-
BOG
13h 00m
2 stops
Delta Logo
5:00 am - 12:32 am
BOG
-
SDF
18h 32m
2 stops
$647Delta
Mon, Jul 13 - Wed, Aug 5
LATAM Airlines Logo
7:05 am - 8:10 pm
SDF
-
BOG
14h 05m
2 stops
LATAM Airlines Logo
11:00 am - 12:24 am
BOG
-
SDF
12h 24m
2 stops
$652LATAM Airlines
Mon, Jul 13 - Wed, Aug 5
American Airlines Logo
6:00 am - 9:17 pm
SDF
-
BOG
16h 17m
1 stop
American Airlines Logo
6:30 am - 10:37 pm
BOG
-
SDF
15h 07m
1 stop
$667American Airlines
Tue, Sep 22 - Mon, Sep 28
United Airlines Logo
3:41 pm - 11:25 pm
SDF
-
UIO
8h 44m
1 stop
United Airlines Logo
12:35 am - 7:35 pm
UIO
-
SDF
18h 00m
1 stop
$685United Airlines
Tue, Sep 22 - Mon, Sep 28
United Airlines Logo
9:00 am - 11:25 pm
SDF
-
UIO
15h 25m
2 stops
United Airlines Logo
12:35 am - 4:49 pm
UIO
-
SDF
15h 14m
2 stops
$690United Airlines
Fri, Oct 16 - Mon, Oct 19
American Airlines Logo
6:45 am - 12:00 pm
SDF
-
BAQ
6h 15m
1 stop
American Airlines Logo
2:10 pm - 12:36 am
BAQ
-
SDF
9h 26m
1 stop
$722American Airlines
Tue, Jun 16 - Sat, Jun 20
Copa Airlines Logo
9:00 am - 12:32 pm
SDF
-
UIO
28h 32m
2 stops
Copa Airlines Logo
8:21 am - 9:26 am
UIO
-
SDF
24h 05m
2 stops
$853Copa Airlines
Thu, Jun 18 - Tue, Jun 23
Copa Airlines Logo
6:15 am - 8:43 pm
SDF
-
UIO
15h 28m
2 stops
Copa Airlines Logo
6:00 am - 8:01 pm
UIO
-
SDF
13h 01m
2 stops
$971Copa Airlines
Booking Insights

KAYAK's insights & trends for Louisville to South America flights

Get data-powered insights and trends into flights from Louisville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Louisville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Louisville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Louisville to South America is September, when tickets cost $254 (return) on average. On the other hand, the most expensive months are July and November, when the average cost of round-trip tickets is $664 and $640 respectively.

Good to know

Low seasonFebruary
Cheapest flight$319
Best time to beat the crowds but there is an average 64% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from Louisville to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Louisville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Louisville to South America

 
Need help choosing which airline to fly with from Louisville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8453 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.2Food
7.8Comfort
Airline reviews

It was a pleasant surprise to have complimentary Wi-Fi on the flight

10.0 ExcellentDamon, May 2026
BOS - MSP
Read more Delta reviews

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

WiFi didn’t exist , seats were super cramped, lights stayed on near my seat for a long time while others were dimmed, the food/trash/drink cart hit my shoulder at least a couple of times while moving, food options were down to just one option by the time it got to my row, the utensils were garbage (knife bent at a couple of places by the time I was done eating) the spoon was very flimsy plastic

Friendliest Flight Attendant I’ve seen since I flew on Southwest Airlines. The whole trip was outstanding…and arrived Early!

It was good overall except from Omaha to Denver when flight a was a repeatedly delayed apparently due to some issue at Denver. Communications could have been handled better. I had to board then deboard with luggage and board again

I didn’t have a seat assignment and my seat was very dirty on the flight from Frankfurt to Budapest.

Left an hour and a half after the listed time. Up side was it had TV screens on the seat.

No screens or meal options. Freezing cold. Dirty seats. Left late.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Cree was organized and pleasant. Plane had good seating but as it’s a shuttle toilets hadn’t been thoroughly cleaned (eg. bins too full)

I liked that my son and I were reseated next to each other (we had different bookings). I liked that it was a directg flight and mostly on time. I liked that you provided pillows and blankets. Flight attendants were generally courteous. The messaging through wifi did not work well. The food was not good. Seats are very narrow and I felt slightly claustraphobic in the window seat.

Overall a good experience, but no wifi available for free or for purchase and we got wet from condensation or other water source during descent.

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Flight was delayed an no one cares, or try to help passengers to get the conexión.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

The small flights with Valet Luggage has a poor service

Terrible, horrible, disappointing- without telling us they changed planes and moved and separated our seats to opposite sides - said they changed seats putting us together - got to airport to find no, they did not - we sat opposing sides of plane - food overly salty to inedible, never saw stewardess but once - it was terrible

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

The crew was very attentive through out the flight. Seats were comfortable, nice flight bag with pillow and blanket. Food was okay, since it was a overnight flight seemed to go by fast.

There was no flight. Spirit went bankrupt Right before my departure and kayak did not refund me any money. I would like my refund kayak. How can I get it? Please let me know. Thank you

Flights were canceled due to airline shutting down and haven’t received a reimbursement. Had to book last minute new flights which were expensive

My flight was canceled the morning of the flight. I had to rebook a flight with a different airline that cost me $900 out of my pocket

Are you serious? I know this is an automated message but how can you not update the system?

Had a flight change had to get a credit.will I get my money back.

Shut down without prior notice End up with spending lots of extra $$$

There was a crack in my window seal. And Spirit is now closed forever.

The company went out of business and now I'm stuck in Ft. Lauderdale. Would not recommend.

Spirit changed flight times by 12 hours with coming and going so I refunded tickets and drove

The airline cancel mi flight, lost a lot of money!!!

Everything you need to know for your flight to South America

Information on your arrival and departure airports