$274 Find Cheap Flights from Louisville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South America departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Louisville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$619
Bogotá
Bogotá1 stop$461
Santiago
Santiago1 stop$835
Quito
Quito1 stop$660
Guayaquil
Guayaquil1 stop$506
Montevideo
Montevideo2 stops$1,363
Barranquilla
Barranquilla2 stops$640
Lima
Lima1 stop$619
Bogotá
Bogotá1 stop$461
Santiago
Santiago1 stop$835
Quito
Quito1 stop$660
Guayaquil
Guayaquil1 stop$506
Montevideo
Montevideo2 stops$1,363
Barranquilla
Barranquilla2 stops$640

Book Cheap Louisville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South America

Mon, Mar 23 - Tue, Mar 31
Multiple Airlines Logo
9:13 pm - 1:11 pm
SDF
-
BOG
16h 58m
1 stop
Multiple Airlines Logo
12:50 pm - 11:14 am
BOG
-
SDF
21h 24m
1 stop
$461Multiple Airlines
Fri, Mar 20 - Fri, Apr 17
Multiple Airlines Logo
9:09 pm - 1:11 pm
SDF
-
BOG
17h 02m
1 stop
Multiple Airlines Logo
2:07 pm - 5:04 pm
BOG
-
SDF
25h 57m
1 stop
$468Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
Spirit Airlines Logo
12:42 pm - 1:11 pm
SDF
-
BOG
25h 29m
1 stop
Spirit Airlines Logo
12:50 pm - 11:14 am
BOG
-
SDF
21h 24m
1 stop
$497Spirit Airlines
Tue, Mar 24 - Tue, Mar 31
Spirit Airlines Logo
12:42 pm - 11:55 am
SDF
-
BOG
24h 13m
2 stops
Spirit Airlines Logo
2:10 pm - 11:14 am
BOG
-
SDF
20h 04m
2 stops
$500Spirit Airlines
Tue, May 5 - Wed, May 13
American Airlines Logo
6:06 am - 9:12 pm
SDF
-
GYE
16h 06m
1 stop
American Airlines Logo
6:05 am - 11:59 pm
GYE
-
SDF
16h 54m
1 stop
$633American Airlines
Tue, May 5 - Wed, May 13
American Airlines Logo
6:06 am - 1:31 pm
SDF
-
GYE
8h 25m
1 stop
American Airlines Logo
6:05 am - 7:02 pm
GYE
-
SDF
11h 57m
2 stops
$638American Airlines
Thu, Apr 9 - Tue, Apr 21
Delta Logo
5:35 pm - 5:00 am
SDF
-
LIM
12h 25m
1 stop
Delta Logo
12:05 am - 4:42 pm
LIM
-
SDF
15h 37m
1 stop
$659Delta
Sun, Apr 12 - Sun, Apr 19
LATAM Airlines Logo
7:05 am - 6:59 pm
SDF
-
UIO
12h 54m
1 stop
LATAM Airlines Logo
6:50 pm - 12:11 pm
UIO
-
SDF
16h 21m
2 stops
$660LATAM Airlines
Sun, Apr 12 - Sun, Apr 19
Delta Logo
7:45 am - 4:43 am
SDF
-
UIO
21h 58m
2 stops
Delta Logo
6:50 pm - 4:40 pm
UIO
-
SDF
20h 50m
2 stops
$662Delta
Mon, Jun 8 - Thu, Jul 9
LATAM Airlines Logo
10:43 am - 8:15 am
SDF
-
LIM
22h 32m
2 stops
LATAM Airlines Logo
8:55 am - 9:55 am
LIM
-
SDF
24h 00m
2 stops
$668LATAM Airlines
Booking Insights

KAYAK's insights & trends for Louisville to South America flights

Get data-powered insights and trends into flights from Louisville to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Louisville and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Louisville to South America.

There is just one airline that flies from Louisville to South America direct and that is Spirit Airlines. The best round-trip deal found from Spirit Airlines for the route is to Cartagena (CTG) and costs $255.

Which airlines provide the cheapest flights from Louisville to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Louisville to South America were found on American Airlines ($575) and LATAM Airlines ($620).

Good to know

Low seasonFebruary
Cheapest flight$239
Best time to beat the crowds but there is an average 39% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from Louisville to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Louisville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Louisville to South America

 
Need help choosing which airline to fly with from Louisville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8242 reviews
8.5Crew
7.8Entertainment
7.9Comfort
7.2Food
8.1Boarding
Airline reviews

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

8.0 ExcellentSheila, Mar 2026
ATL - EWR
Read more Delta reviews

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Flight was warm for first few hours and quite rough

Seat was extremely hard which made even a short 1 hour 20 minute flight fairly uncomfortable.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

It’s always a great time flying with united airlines.

Good flight. Efficient boarding and competent flight crew. No problems until we arrived at our destination gate. We were early so there was an aircraft at the gate that had to move before we could pull in. Then, due to the type of aircraft we flew, the cabin door could not be opened until some luggage from the cargo bay was offloaded to preserve center of gravity characteristics. So, that further delayed deplaning. Despite being 20 minutes early on landing, we ended up being 5 to 10 minutes late after all the delays.

Everything went well except the turbulence what no one have a control of but pilot and crew handled very good!

There was no WiFi available, there were mechanical problems with the plane and we landed at C 124, then the gate was switched to A 26, then all the way back to C126! For a 75 yo woman traveling alone, this was a difficult journey, indeed!

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Complimentary light meal would be appreciated. But great flight crew service on all legs

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We got delayed three hours and nobody thought to have the bathroom fixed while we were sitting waiting to board? took a full hour to have maintenance come and check it off. Had to shut the bathroom down twice so that the pilots could go to the bathroom. Everyone missed their connections.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

Delayed initially because they couldn’t print the flight details. Poor instruction on delay. When I got on the plane the flight attendant argued with me about whether my carry on would fit (it did, although she didn’t acknowledge that). No greeting (other than arguing with me) getting on or off the plane.

Overall good. The pilots and flight attendants are excellent! The equipment was the issue on my First flight as they had to wait for a part to be installed. So the take off was at least 30 minutes later.

The worst Airline ever. They centered my second flight and leave me in NY. They don’t have any representatives at the airport and they don’t respond to calls. Basically I got stuck. I will never purchase through there again.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Mediocre would be best description. Food bland. Seat biz class uncomfortable to sleep. Crew never dimmed lights completely in an overnight flight to Europe. Would avoid AA if possible.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

It was good experience this time. The flight was on time.

Bad. I know TSA is a mess right now but they “overbooked” the flight and almost didn’t let 10 of us on. Can’t put even a normal backpack under the seat, tray table is barely a foot wide, have to pay for literally everything. Apparently you can bid on your seats, too, so really the baseline ticket only covers the possibility of maybe getting on the plane. The staff were nice though, can only imagine the stress they are under.

I was double booked for my ticket- they have record of it and admitted to their error but wouldn’t let me board until I paid once again for the fare- have documentation of their mistake -

The flight time did not match my original email on time of flight. Missed the first flight. The representative I got on the phone was so incompetent it was unbelievable. My guess is it was AI but it told me it was not AI. They did get me rebooked which I was very thankful of. The return flight was delayed because of staffing issues for the plane and when we reached our destination the jet bridge would not work so we sat on the plane another 40 minutes. I did get to my destination and I did get home but not a good experience.

My flight was cancelled I missed time at work and got a parking ticket

It was terrible. I had to pay again once I got to the airport because they said they never received the payment.

Customer service online / on the phone are horrible. Flight crew is great but gate agents and customer service are terrible

bought basic spirit fares, add checked bags - like the up front info on website about this. bring your own snacks, buy a soda after TSA security to bring with you, or buy on the plane (limited selection) all in all, a good experience

I cannot effectively rate the food and drink as I had not. Otherwise, the trip was fine. The seats were nice, the crew was fine. They could smile once in a while. They all look like they were mad.

4 hour delay, 2 hours in the airport and then 2 hours on the tarmac. With a flight full of kids it would have been better to leave us in the airport for the delay, it was crying kids chaos on the flight. Miserable. And no apology or airline credit for the significant delay.

Flight was on time with no issues. Price is very competitive. Flight schedule works well for me

Everything you need to know for your flight to South America

Information on your arrival and departure airports