$196 Find Cheap Flights from Louisville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South America departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Louisville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$433
Bogotá
Bogotá1 stop$431
Santiago
Santiago2 stops$809
Quito
Quito1 stop$725
Guayaquil
Guayaquil2 stops$693
Montevideo
Montevideo2 stops$970
Barranquilla
Barranquilla2 stops$398
Lima
Lima1 stop$433
Bogotá
Bogotá1 stop$431
Santiago
Santiago2 stops$809
Quito
Quito1 stop$725
Guayaquil
Guayaquil2 stops$693
Montevideo
Montevideo2 stops$970
Barranquilla
Barranquilla2 stops$398

Book Cheap Louisville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South America

Mon, Jan 26 - Mon, Feb 9
Spirit Airlines Logo
1:55 pm - 2:41 pmSDF-BAQ
24h 46m2 stops
Spirit Airlines Logo
3:36 pm - 2:33 pmBAQ-SDF
22h 57m1 stop
$398Spirit Airlines
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Mon, Dec 8 - Wed, Dec 10
Spirit Airlines Logo
11:55 am - 1:12 amSDF-BOG
13h 17m1 stop
Spirit Airlines Logo
2:17 am - 11:00 amBOG-SDF
8h 43m1 stop
$431Spirit Airlines
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Thu, Mar 19 - Mon, Mar 23
Multiple Airlines Logo
3:33 pm - 6:10 pmSDF-BOG
27h 37m1 stop
Multiple Airlines Logo
9:15 am - 2:38 pmBOG-SDF
28h 23m1 stop
$473Multiple Airlines
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Mon, Dec 15 - Sun, Dec 21
Multiple Airlines Logo
11:55 am - 9:45 amSDF-BOG
45h 50m2 stops
Multiple Airlines Logo
2:17 am - 11:59 pmBOG-SDF
21h 42m1 stop
$490Multiple Airlines
Find Deal
Mon, Feb 23 - Wed, Feb 25
Delta Logo
7:05 am - 8:00 amSDF-LIM
24h 55m2 stops
Delta Logo
8:00 am - 9:15 pmLIM-SDF
13h 15m2 stops
$549Delta
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Mon, Jan 26 - Mon, Feb 9
American Airlines Logo
6:00 am - 1:33 pmSDF-BAQ
7h 33m1 stop
American Airlines Logo
2:33 pm - 10:38 amBAQ-SDF
20h 05m2 stops
$550American Airlines
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Mon, Feb 2 - Wed, Feb 4
Delta Logo
5:35 am - 12:22 amSDF-BAQ
18h 47m2 stops
Delta Logo
4:48 am - 8:56 pmBAQ-SDF
16h 08m2 stops
$615Delta
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Mon, Jan 26 - Mon, Feb 9
American Airlines Logo
6:00 am - 1:33 pmSDF-BAQ
7h 33m1 stop
American Airlines Logo
2:33 pm - 11:59 pmBAQ-SDF
9h 26m1 stop
$705American Airlines
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Sat, Dec 6 - Tue, Dec 9
LATAM Airlines Logo
6:11 pm - 7:40 amSDF-SCL
11h 29m1 stop
LATAM Airlines Logo
4:35 am - 11:59 pmSCL-SDF
21h 24m2 stops
$874LATAM Airlines
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Sat, May 9 - Sat, May 16
LATAM Airlines Logo
12:40 pm - 6:55 amSDF-SCL
18h 15m2 stops
LATAM Airlines Logo
11:25 pm - 11:59 pmSCL-SDF
24h 34m3 stops
$959LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Louisville to South America flights

Get data-powered insights and trends into flights from Louisville to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Louisville and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Louisville to South America.

There are 4 airlines that fly nonstop from Louisville to South America. They are: American Airlines, LATAM Airlines, Delta and Spirit Airlines. The cheapest price of all airlines flying this route was found with Spirit Airlines at $254 for a round-trip flight to Lima (LIM). On average, Spirit Airlines offers the best prices for nonstop flights between Louisville and South America.

Which airlines provide the cheapest flights from Louisville to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Louisville to South America were found on Spirit Airlines ($398) and United Airlines ($547).

Good to know

Low seasonOctober
Cheapest flight$196
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 44% increase in price.
Flight from Louisville to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Louisville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $737 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $787.

Reviews of the top 4 airlines serving from Louisville to South America

 
Need help choosing which airline to fly with from Louisville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8003 reviews
8.5Crew
7.9Entertainment
7.9Comfort
7.3Food
8.1Boarding
Airline reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

8.0 ExcellentAnonymous, Nov 2025SFO - MSP
Read more Delta reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

We were very rushed by a staff member at the gate when transferring from American Airlines to Fijian. Then the plane stayed put for ages anyhow! The plane was delayed and my bag sent to San Francisco instead of Fiji

Bought round trip tickets. Ended up upgrading to first class. Both flights were new planes but hadn’t been equipped with WiFi and there were no charging ports at my seat despite it being new and first class accommodations.

The flight was on time and the crew was very professional and accommodating. When other airlines are canceling flights Spirit is still flying with on time flights. I have no complaints and will continue to choose Spirit when it is the best option for me.

Very uncomfortable seat. Hard bar under cushion. Flight had no solution except to walk a around at times

Endless, trip oof my life, we still are in in plane waiting for getting off.after 3 hours delay. Not even a glass of water.

It was cheap. Spirit is what it is. I got to my destination and home safely. There was no food or entertainment without paying extra, which is fine. That’s why the flight was inexpensive.

Like: seats that don't move; fast boarding; engaging crew; low-prices; individual gate at LGA; access to restrooms at the gate Dislike: no water on the flight

No leg room. My knee was sore for a day.

It was better than expected. But there were two delays in taking off.

To be Honest they canceled my flight and didn't have other options. Until 4 says later and I have a 2yr old very disappointed.

The whole thing everything was poorly managed poorly handled spirit doent deserve to be in business period.

Everything you need to know for your flight to South America

Information on your arrival and departure airports