$229 Find Cheap Flights from Louisville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South America departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Louisville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$695
Bogotá
Bogotá1 stop$443
Santiago
Santiago2 stops$980
Quito
Quito1 stop$665
Guayaquil
Guayaquil2 stops$462
Montevideo
Montevideo2 stops$991
Barranquilla
Barranquilla2 stops$711
Lima
Lima1 stop$695
Bogotá
Bogotá1 stop$443
Santiago
Santiago2 stops$980
Quito
Quito1 stop$665
Guayaquil
Guayaquil2 stops$462
Montevideo
Montevideo2 stops$991
Barranquilla
Barranquilla2 stops$711

Book Cheap Louisville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to South America

Sun, Mar 29 - Sun, Apr 5
Spirit Airlines Logo
3:33 pm - 1:11 pm
SDF
-
BOG
22h 38m
1 stop
Spirit Airlines Logo
12:50 pm - 11:14 am
BOG
-
SDF
21h 24m
1 stop
$443Spirit Airlines
Wed, Apr 1 - Wed, Apr 22
Spirit Airlines Logo
12:09 pm - 11:04 pm
SDF
-
GYE
35h 55m
2 stops
Spirit Airlines Logo
11:59 pm - 5:04 pm
GYE
-
SDF
16h 05m
1 stop
$462Spirit Airlines
Mon, May 11 - Sun, May 17
United Airlines Logo
5:40 am - 7:20 pm
SDF
-
BOG
14h 40m
2 stops
United Airlines Logo
12:14 am - 8:00 pm
BOG
-
SDF
18h 46m
1 stop
$579United Airlines
Wed, Apr 29 - Tue, May 5
American Airlines Logo
11:00 am - 10:30 pm
SDF
-
BOG
12h 30m
1 stop
American Airlines Logo
12:25 am - 12:48 pm
BOG
-
SDF
11h 23m
1 stop
$598American Airlines
Wed, Apr 29 - Wed, May 6
American Airlines Logo
6:06 am - 9:17 pm
SDF
-
BOG
16h 11m
1 stop
American Airlines Logo
6:30 am - 10:08 pm
BOG
-
SDF
14h 38m
2 stops
$603American Airlines
Tue, May 12 - Mon, May 25
LATAM Airlines Logo
7:08 am - 6:59 pm
SDF
-
UIO
12h 51m
1 stop
LATAM Airlines Logo
12:59 am - 7:50 pm
UIO
-
SDF
17h 51m
1 stop
$665LATAM Airlines
Tue, May 19 - Tue, May 26
LATAM Airlines Logo
7:08 am - 6:59 pm
SDF
-
UIO
12h 51m
1 stop
LATAM Airlines Logo
6:50 pm - 10:25 am
UIO
-
SDF
14h 35m
2 stops
$668LATAM Airlines
Mon, May 11 - Wed, May 27
Delta Logo
3:37 pm - 4:43 am
SDF
-
UIO
14h 06m
2 stops
Delta Logo
6:50 pm - 10:25 am
UIO
-
SDF
14h 35m
2 stops
$670Delta
Sun, May 10 - Sun, May 24
Delta Logo
7:59 pm - 6:59 pm
SDF
-
UIO
24h 00m
1 stop
Delta Logo
12:59 am - 12:25 am
UIO
-
SDF
22h 26m
1 stop
$676Delta
Sun, May 10 - Wed, May 13
United Airlines Logo
6:00 am - 11:38 pm
SDF
-
BAQ
18h 38m
2 stops
United Airlines Logo
9:13 am - 9:59 pm
BAQ
-
SDF
35h 46m
2 stops
$711United Airlines
Booking Insights

KAYAK's insights & trends for Louisville to South America flights

Get data-powered insights and trends into flights from Louisville to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Louisville and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Louisville to South America.

There is just one airline that flies from Louisville to South America direct and that is Spirit Airlines. The best round-trip deal found from Spirit Airlines for the route is to Cartagena (CTG) and costs $255.

Which airlines provide the cheapest flights from Louisville to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Louisville to South America were found on Spirit Airlines ($443) and United Airlines ($579).

Good to know

Low seasonFebruary
Cheapest flight$229
Best time to beat the crowds but there is an average 51% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Louisville to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Louisville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Louisville to South America

 
Need help choosing which airline to fly with from Louisville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8300 reviews
7.9Comfort
7.2Food
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

8.0 ExcellentSunderesh, Mar 2026
ATL - LIM
Read more Delta reviews

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Business class seats felt very cramped compared to other airlines.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

I rated the experience "mediocre" because of the 2 hour delay in take off. This is the 4th flight from DFW on AA where there was a delay and in one of the instances (after 13 delays), the flight was cancelled. I understand weather but for the March 18th flight, there was no weather issue in Dallas or Detroit. I called Concierge Key and they were wonderful, booking me on a later flight in case my flight was cancelled. I have flown with American for many years and never has there been this consistent pattern of delays. Very disappointing.

They put me on an earlier and I got home sooner

Not good. One of my luggage is missing. And until now they can’t find it

Horrible experience upon landing. Probably more due to DCA utter incompetence than AA.

Jill was the flight attendant in first class she was fabulous!! Best flight attendant I have had in years.!! And I fly every other week. Other can learn from her!!

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

My 9:50AM flight was delayed to 3:40PM "due to incoming aircraft delay". No aircraft is "delayed" that long. Found out once we did board (after several changes in times) that the aircraft had a maintenance issue and we had to wait for another aircraft. Just tell us that. The aircraft we did get was old and the seats need to be updated. I have been traveling for several weeks with AA and you should refresh your entertainment content as frequent flyers have gone through most of your new content. I have Celiac and a shellfish allergy and continue to have struggles with meals on business and first class flights. Please keep this in mind. Sorry - was a long travel day yesterday and a bit cranky this morning with my experience comments. Still an AA fan.

The business steward was absolutely amazing! Smiles and kindness! Wish all AA flights are like this one!

As a first class customer, there was no power the entire flight which limited my ability to work. I find this unacceptable. The first 11 rows on the left side of the plan were out. I was only offered the option to charge my phone which was not the issue because my laptop was out of power. I asked if there was anything that can be done for me, and the answer was, "no". I was not offered any type of compensation for this AA problem which caused me unnecessary stress due to inability to address business issues on an already challenging travel day. Flight attendants tried to reset the power once but that was the extent of their support. Very disappointing for the lack of expected services on a flight. Please contact me with customer focused response to this complaint.

Not really sure I enjoyed the flight at all. The flight attendants seemed a little tired and rude at times. The snacks were lacking in taste and sustenance. The flight was incredibly turbulent for three plus hours and the pilot had to do a second pass to land at our final destination because he was coming in so fast. He must have taken a short cut and because of it we had to suffer the violent turbulence and the dropping down. It had to be one of if not the worse flights I have ever been on and have traveled vastly all over the world.

I never had an opportunity to experience them! They cancelled my flight TWICE!!!

Return flight was canceled. Needed to reschedule with another airline the next day. Cost an an additional $84. At another airport 45 miles further away

Spent seven hours in the airport with spirit pushing he flight time back two hours every two hours only to then have it canceled without explanation. The employees said, “They’ve been doing this for the last five days.” Would have been great if they told us to expect that when we arrived.

Seat do not reclined and tight space. Flight changed so many times hard to keep up.

Bad airline to travel with my flight was delayed for more than 3 hours they act like it’s normal

No WiFi, no outlets to charge phones, no complimentary beverages on a 6 hour flight

Length of flight was fine Delay of over 3 hours was very bad!! Flight down was delayed 1.5 hours

Delayed 11 hours with two being on our destinations tarmac, no compensation or refund and was told I would actually get charged a $200 cancellation fee if I decided to switch airlines for my return flight. For their inconvenience they gave a $10 meal voucher to split between two people in a airport.

Absolutely terrible, flight was cancelled and we missed our cruise. Will never fly Spirit again.

Horrendous and unprofessional staff and will never fly spirit again

Everything you need to know for your flight to South America

Information on your arrival and departure airports