MSN - TYS

$235 Find Cheap Flights from Madison to Knoxville - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$337
Typical prices: $358-$470
United Airlines
Mon 1/15Fri 1/19
MSN - TYS • 1 stop
Cheapest one-way
$235
Typical prices: $199-$248
Delta
Fri 11/2
MSN - TYS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Madison and Knoxville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
March
Cheapest • 20% price drop
September
Most popular
Good to know
+1
Good to know
+1
Top layover airports
New York LaGuardia (LGA)
Cheapest • Avg $284 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 4h 24m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Madison to Knoxville (MSN-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madison to Knoxville

Fri, Jan 15 - Tue, Jan 19
United Airlines Logo
5:00 am - 10:10 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
4h 10m1 stop Chicago O'Hare Intl
United Airlines Logo
5:55 pm - 8:56 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 01m1 stop Chicago O'Hare Intl
$337United Airlines
Thu, Dec 3 - Sun, Dec 6
American Airlines Logo
5:00 am - 11:02 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 02m1 stop Chicago O'Hare Intl
American Airlines Logo
11:22 am - 2:42 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 20m1 stop Chicago O'Hare Intl
$339American Airlines
Fri, Nov 13 - Mon, Nov 16
Delta Logo
5:20 pm - 11:59 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 39m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 pm - 10:50 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
5h 40m1 stop Atlanta Hartsfield-Jackson
$339Delta
Thu, Apr 1 - Mon, Apr 5
Delta Logo
5:17 pm - 11:46 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 29m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:20 pm - 10:34 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 14m1 stop Atlanta Hartsfield-Jackson
$339Delta
Fri, Nov 13 - Fri, Nov 20
American Airlines Logo
6:38 pm - 11:58 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
4h 20m1 stop Charlotte Douglas
American Airlines Logo
11:34 am - 2:59 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 25m1 stop Chicago O'Hare Intl
$339American Airlines
Fri, Oct 30 - Tue, Nov 3
American Airlines Logo
7:05 pm - 11:59 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
3h 54m1 stop Chicago O'Hare Intl
American Airlines Logo
7:52 am - 10:55 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 03m1 stop Chicago O'Hare Intl
$369American Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
5:00 am - 10:10 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
4h 10m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 11:46 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
6h 16m1 stop Chicago O'Hare Intl
$435United Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
1:32 pm - 9:05 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
6h 33m1 stop Chicago O'Hare Intl
United Airlines Logo
1:55 pm - 4:46 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
3h 51m1 stop Chicago O'Hare Intl
$435United Airlines
Thu, Oct 29 - Mon, Nov 2
Multiple Airlines Logo
6:00 pm - 12:14 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
17h 14m1 stop Orlando
Multiple Airlines Logo
8:14 pm - 9:58 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
38h 44m2 stops Fort Lauderdale Tampa
$465Multiple Airlines
Fri, Nov 13 - Mon, Nov 16
Delta Logo
1:24 pm - 11:59 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
9h 35m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 12:39 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
6h 39m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County
$1,536Delta
Booking Insights

Price, demand and travel trends for Madison to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Madison to Knoxville?

Round-trip flights from Madison to Knoxville typically range from $358 to $470. The lowest price found in the past 5 days was $337, on United Airlines.

What's the cheapest day of the week to fly from Madison to Knoxville?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Madison to Knoxville. It’s 7% cheaper than the average day, while Sunday is the most expensive, with prices 16% higher.

What’s the cheapest month to fly from Madison to Knoxville?

•March is the cheapest month to fly from Madison to Knoxville at $326 round-trip.
•February ($533) and October ($470) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 63% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

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Key details for Madison to Knoxville flights

Low season

February

Cheapest flight

$235
Beat the crowds with an average 58% drop in travelers.
The most popular month to fly with an average 81% increase in travelers.
One-way flight from Madison to Knoxville

When to book flights from Madison to Knoxville

Are your dates flexible? Find out the best times to travel from Madison to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Madison to Knoxville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Madison to Knoxville?

    Only Economy Class is available on flights from Madison to Knoxville.

  • How long is a flight from Madison to Knoxville?

    A nonstop flight from Madison to Knoxville takes 00m, covering 580 miles.

  • Do I need a passport to fly from Madison to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Madison to Knoxville flight?

    Round-trip flights from Madison to Knoxville range from $358 to $470, with an average of $406 over the past 12 months. Anything below $358 counts as a good deal.

  • Have flight prices from Madison to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $337 to $2,462. That means the highest observed fare was about 7x higher than the lowest one.

  • How are flight prices from Madison to Knoxville looking right now?

    One-way fares from Madison to Knoxville are currently higher than usual. Average one-way flight prices are about $569, which is 161% above the typical average for this route.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:

    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Thrifty
    • Avis

  • Which airports can I use when flying from Madison to Knoxville?

    Flights from Madison to Knoxville usually depart from Madison Truax Field (MSN) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airports do connecting flights from Madison to Knoxville pass through?

    One-stop flights from Madison to Knoxville most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 63% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 16% of one-stop connections
    • Charlotte Douglas (CLT) - 12% of one-stop connections
    • Denver Intl (DEN) - 4% of one-stop connections

  • Can I save money by using flexible dates for flights from Madison to Knoxville?

    Yes. Flexible dates can save you up to 21% on flights from Madison to Knoxville. Wednesday is the cheapest departure day at $378 round-trip on average, while Sunday is the most expensive at $474, a difference of $96.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Madison to Knoxville?

    Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 4h 24m, compared with 5h via Charlotte Douglas (CLT) and 5h 14m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Madison and Knoxville?

    Knoxville is 1 hour ahead of Madison (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Madison to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Sunday. On this route, Wednesday flights average $378, about $96 less than Sunday fares (20% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Madison to Knoxville trip for March. Fares historically average $326 round-trip in that month - typically $207 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Madison to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Car rentals in Knoxville
Hotels in Knoxville
Vacations in Knoxville