MSN - TYS

$146 Find Cheap Flights from Madison to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madison to Knoxville departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madison to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madison to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$285
Typical prices: $386-$280
American Airlines
Sat 5/16Wed 5/20
MSN - TYS • 1 stop
Cheapest one-way
$146
Typical prices: $162-$180
American Airlines
Wed 5/20
MSN - TYS • 1 stop
Top airlines
American Airlines
Cheapest • from $285 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Madison and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $271 (round-trip)
Chicago (ORD)
Shortest trip • 4h 21m (one-way)
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 21% price drop
August
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Madison to Knoxville (MSN-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madison to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madison to Knoxville

Sat, May 16 - Wed, May 20
American Airlines Logo
3:03 pm - 8:18 pm
MSN
-
TYS
4h 15m
1 stop
American Airlines Logo
4:09 pm - 10:32 pm
TYS
-
MSN
7h 23m
1 stop
$285American Airlines
Fri, Aug 14 - Sat, Aug 22
Delta Logo
5:17 pm - 11:47 pm
MSN
-
TYS
5h 30m
1 stop
Delta Logo
5:30 am - 10:11 am
TYS
-
MSN
5h 41m
1 stop
$307Delta
Tue, May 19 - Sun, May 24
American Airlines Logo
10:19 am - 4:39 pm
MSN
-
TYS
5h 20m
1 stop
American Airlines Logo
5:36 am - 10:38 am
TYS
-
MSN
6h 02m
1 stop
$310American Airlines
Thu, Aug 20 - Mon, Aug 24
American Airlines Logo
3:50 pm - 9:33 pm
MSN
-
TYS
4h 43m
1 stop
American Airlines Logo
7:07 am - 12:01 pm
TYS
-
MSN
5h 54m
1 stop
$329American Airlines
Fri, Aug 14 - Sat, Aug 22
American Airlines Logo
12:39 pm - 9:33 pm
MSN
-
TYS
7h 54m
1 stop
American Airlines Logo
6:00 am - 10:40 am
TYS
-
MSN
5h 40m
1 stop
$332American Airlines
Fri, May 8 - Sun, May 10
American Airlines Logo
1:05 pm - 9:57 pm
MSN
-
TYS
7h 52m
1 stop
American Airlines Logo
6:00 am - 11:14 am
TYS
-
MSN
6h 14m
1 stop
$334American Airlines
Sat, May 2 - Wed, May 6
American Airlines Logo
11:35 am - 5:07 pm
MSN
-
TYS
4h 32m
1 stop
American Airlines Logo
6:38 pm - 11:28 pm
TYS
-
MSN
5h 50m
1 stop
$339American Airlines
Thu, May 28 - Sat, May 30
American Airlines Logo
5:00 am - 12:35 pm
MSN
-
TYS
6h 35m
2 stops
American Airlines Logo
6:12 am - 12:03 pm
TYS
-
MSN
6h 51m
1 stop
$341American Airlines
Thu, Sep 17 - Mon, Sep 21
Multiple Airlines Logo
4:40 pm - 12:41 pm
MSN
-
TYS
19h 01m
1 stop
Multiple Airlines Logo
4:18 pm - 4:00 pm
TYS
-
MSN
24h 42m
1 stop
$348Multiple Airlines
Tue, Jul 21 - Sat, Aug 1
American Airlines Logo
5:00 am - 12:34 pm
MSN
-
TYS
6h 34m
2 stops
American Airlines Logo
6:07 pm - 12:05 am
TYS
-
MSN
6h 58m
1 stop
$349American Airlines
Booking Insights

KAYAK's insights & trends for Madison to Knoxville flights

Get data-powered insights and trends into flights from Madison to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Madison to Knoxville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Madison to Knoxville departing in May.

What is the cheapest month to fly from Madison to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madison to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madison to Knoxville is May, where tickets cost $298 (return) on average. On the other hand, the most expensive months are February and November, where the average cost of round-trip tickets is $533 and $477 respectively.

Find deals

Good to know

Low seasonMarch
Cheapest flight$146
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from Madison to Knoxville

When to book flights from Madison to Knoxville

Are your dates flexible? Find out the best times to travel from Madison to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madison to Knoxville

  • What is the cheapest flight from Madison to Knoxville?

    In the last 3 days, the lowest price for a flight from Madison to Knoxville was $146 for a one-way ticket and $285 for a round-trip.

  • Do I need a passport to fly between Madison and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Madison to Knoxville?

    On your way to Knoxville, you’ll fly out from Madison Truax Field. You’ll be landing at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Madison to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Madison to Knoxville?

    oneworld is the only airline alliance operating flights between Madison and Knoxville.

  • How does KAYAK find such low prices on flights from Madison to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madison to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madison to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Madison is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madison to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Madison with another airline. Booking your flights between Madison and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madison to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Madison up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Madison to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Madison to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madison to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11645 reviews
7.5Boarding
6.4Food
7.2Comfort
7.9Crew
6.9Entertainment
Airline reviews

The crew was very kind, but no in-flight entertainment monitors and a 2 hour and 30 minute delay was extremely frustrating.

6.0 GoodMichael, Apr 2026
DFW - SLC
Read more American Airlines reviews

The crew was very kind, but no in-flight entertainment monitors and a 2 hour and 30 minute delay was extremely frustrating.

Everything was delayed and the staff sent me to the wrong gate, causing me to miss one of my flights. I arrived at my destination 6 hours later than I was supposed to.

Got home at 3am after deboarding the plane. No compensation offered by American

Delayed flight. Missed connection, AA put us on a later connecting flight. The connection flight was delayed 4 times and we had to deplane. Didnt get home until 3am, when I was supposed to be home at 8:30p. Zero compensation offered from American. I would not fly them again.

The seats need better cushioning for a nearly 5-hour flight, it was a bit uncomfortable. I'm glad American has free wi-fi but there were was a bout 30 minutes in the middle of the flight when there was no connection which was frustrating.

My original flight got delayed day of so I had to rebook it from one layover to two layovers. The flight also left earlier which was a slight inconvenience but manageable. Then my first connection flight got delayed 3 separate times for a total of 2 hours delayed, causing me to miss my second connection flight back to Santa Barbara. Now, because of this missed flight, I am missing my college classes that I pay for.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

It was good, the staff was great, and the food, was as usual, tea and biscuit. Bathroom was clean, and the plane was clean as well.

Early departure meant on time arrival. Only real problem was free internet had issues, although chatting with the internet help desk (you can do this via aainflight.com) got the issue resolved.

It was really a terrific experience both going and returning on AA. Staff and crew were professional.

Everything you need to know for your flight from Madison to Knoxville

Information on your arrival and departure airports

Madison (MSN)
Knoxville (TYS)