MSN - TYS

$163 Find Cheap Flights from Madison to Knoxville - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$295
Typical prices: $349-$470
American Airlines
Wed 10/3Sat 10/6
MSN - TYS • 1 stop
Cheapest one-way
$163
Typical prices: $199-$264
Multiple Airlines
Sat 9/29
MSN - TYS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Madison and Knoxville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
March
Cheapest • 21% price drop
September
Most popular
Good to know
+1
Good to know
+1
Top layover airports
New York LaGuardia (LGA)
Cheapest • Avg $284 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 4h 14m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Madison to Knoxville (MSN-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madison to Knoxville

Sat, Oct 3 - Tue, Oct 6
American Airlines Logo
2:17 pm - 9:06 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 49m1 stop Charlotte Douglas
American Airlines Logo
6:06 pm - 11:39 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
6h 33m1 stop Charlotte Douglas
$295American Airlines
Tue, Sep 29 - Tue, Oct 6
American Airlines Logo
5:00 am - 10:50 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
4h 50m1 stop Chicago O'Hare Intl
American Airlines Logo
11:35 am - 2:55 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 20m1 stop Chicago O'Hare Intl
$295American Airlines
Wed, Oct 21 - Mon, Oct 26
American Airlines Logo
5:00 am - 11:05 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 05m1 stop Chicago O'Hare Intl
American Airlines Logo
6:55 pm - 12:12 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
6h 17m1 stop Chicago O'Hare Intl
$307American Airlines
Fri, Jan 8 - Mon, Jan 11
Delta Logo
11:11 am - 5:13 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:07 am - 10:15 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 08m1 stop Atlanta Hartsfield-Jackson
$319Delta
Fri, Sep 11 - Sun, Sep 13
Delta Logo
5:50 am - 10:44 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
3h 54m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 10:38 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
5h 58m1 stop Atlanta Hartsfield-Jackson
$322Delta
Fri, Sep 11 - Mon, Sep 14
Delta Logo
5:50 am - 10:44 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
3h 54m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:25 pm - 10:41 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 16m1 stop Atlanta Hartsfield-Jackson
$322Delta
Thu, Oct 1 - Tue, Oct 6
United Airlines Logo
5:00 am - 9:45 amMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
3h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 9:54 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
4h 54m1 stop Chicago O'Hare Intl
$342United Airlines
Sat, Oct 3 - Wed, Oct 7
United Airlines Logo
2:49 pm - 8:49 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
5h 00m1 stop Chicago O'Hare Intl
United Airlines Logo
10:42 am - 1:37 pmTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
3h 55m1 stop Chicago O'Hare Intl
$375United Airlines
Sun, Sep 13 - Thu, Sep 17
Multiple Airlines Logo
6:00 pm - 8:39 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
25h 39m1 stop Orlando
Multiple Airlines Logo
5:21 pm - 9:53 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
41h 32m2 stops Fort Lauderdale Tampa
$422Multiple Airlines
Thu, Oct 22 - Mon, Oct 26
Multiple Airlines Logo
6:00 pm - 9:41 pmMSN  Madison Truax Field-TYS Knoxville McGhee Tyson
26h 41m1 stop Orlando
Multiple Airlines Logo
2:12 pm - 9:50 amTYS  Knoxville McGhee Tyson-MSN Madison Truax Field
20h 38m2 stops Philadelphia Orlando
$446Multiple Airlines
Booking Insights

Price, demand and travel trends for Madison to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Madison to Knoxville with more confidence.

How much is a round-trip flight from Madison to Knoxville?

Round-trip flights from Madison to Knoxville start at $295. Prices are below average for this route right now, with typical round-trip fares ranging from $349 to $470. The lowest price found in the past 5 days was $295 on American Airlines.

What's the cheapest day of the week to fly from Madison to Knoxville?

Wednesday is the cheapest day of the week to fly from Madison to Knoxville, it is 9% cheaper than the average day. Friday is the most expensive day with flight prices 16% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Madison to Knoxville?

  • March is the cheapest month to fly from Madison to Knoxville at $326 round-trip.
  • February ($533) and November ($477) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 63% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Madison to Knoxville flights

Low season

February

Cheapest flight

$163
Best time to beat the crowds but there is an average 30% increase in price.
Most popular time to fly with an average 15% increase in price.
Flight from Madison to Knoxville

When to book flights from Madison to Knoxville

Are your dates flexible? Find out the best times to travel from Madison to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Madison to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Madison to Knoxville?

    Flights from Madison to Knoxville usually depart from Madison Truax Field (MSN) and arrive at Knoxville McGhee Tyson (TYS).

  • What cabin classes can I book on flights from Madison to Knoxville?

    Only Economy Class is available on flights from Madison to Knoxville.

  • Which airports do connecting flights from Madison to Knoxville pass through?

    One-stop flights from Madison to Knoxville most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 59% of one-stop connections
    • Charlotte Douglas (CLT) - 18% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 14% of one-stop connections
    • Denver Intl (DEN) - 4% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Madison to Knoxville?

    Yes. Being flexible with your travel dates can save you up to 21% on the Madison to Knoxville route. Wednesday is the cheapest departure day at $378 round-trip on average, while Friday is the most expensive at $477, a difference of $99. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Madison to Knoxville?

    A nonstop flight from Madison to Knoxville takes 0h 00m, covering 580 miles.

  • Do I need a passport to fly from Madison to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Madison to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $295 to $2,568. That means the highest observed fare was about 9x higher than the lowest one.

  • How are flight prices from Madison to Knoxville looking right now?

    One-way fares from Madison to Knoxville are currently in line with typical prices for this route. Average one-way fares are about $235.

  • How much time can I save by choosing a different layover airport from Madison to Knoxville?

    Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 4h 14m, compared with 5h 04m via Charlotte Douglas (CLT) and 5h 11m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Madison and Knoxville?

    Knoxville is 1 hour ahead of Madison (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    · Budget
    · Alamo
    · Thrifty
    · Enterprise Rent-A-Car
    · Payless

  • How much should I expect to pay for a Madison to Knoxville flight?

    Round-trip flights from Madison to Knoxville range from $349 to $470, with an average of $411 over the past 12 months. Anything below $349 counts as a good deal.

Your guide to booking Madison to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Friday. On this route, Wednesday flights average $378 - about $99 less than Friday (21% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Madison to Knoxville trip for March. Fares historically average $326 round-trip in that month - typically $207 less than the most expensive month, which is February (based on the last 12 months).

Everything you need to know for your flight from Madison to Knoxville

Information on your arrival and departure airports

Madison (MSN)
Knoxville (TYS)