MDE - SFO

$315 Find Cheap Flights from Medellín to San Francisco - Compare and Save

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Everything you should know

Cheapest round-trip
$539
Typical prices: $519-$791
Frontier
Fri 2/9Mon 2/26
MDE - SFO • 2 stops
Cheapest one-way
$315
Typical prices: $346-$569
Multiple Airlines
Fri 12/7
MDE - SFO • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Medellín Jose Maria Cordova Intl Airport and San Francisco. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
10 weeks
in advance
Our data shows that travelers who book at least 10 weeks in advance save around 32% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 28% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Fort Lauderdale (FLL)
Cheapest • Avg $551 (round-trip)
San Salvador El Salvador Intl (SAL)
Shortest trip • 11h 05m (one-way)
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Insights
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We hope you love your trip to San Francisco!
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Flight Deals

Cheap Flights from Medellín to San Francisco (MDE-SFO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Francisco

Tue, Feb 9 - Fri, Feb 26
Frontier Logo
1:10 pm - 12:35 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
14h 25m2 stops Orlando Denver Intl
Frontier Logo
3:30 pm - 12:00 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
17h 30m2 stops Las Vegas Harry Reid Intl Orlando
$539Frontier
Mon, Feb 22 - Tue, Mar 2
Frontier Logo
1:10 pm - 12:35 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
14h 25m2 stops Orlando Denver Intl
Frontier Logo
6:30 pm - 12:00 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
14h 30m2 stops Las Vegas Harry Reid Intl Orlando
$546Frontier
Tue, Feb 23 - Tue, Mar 2
Frontier Logo
1:10 pm - 12:35 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
14h 25m2 stops Orlando Denver Intl
Frontier Logo
6:30 pm - 12:00 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
14h 30m2 stops Las Vegas Harry Reid Intl Orlando
$546Frontier
Sun, Apr 11 - Sat, May 1
Avianca Logo
2:10 pm - 10:35 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
10h 25m1 stop San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 1:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
11h 15m1 stop San Salvador El Salvador Intl
$707Avianca
Sun, Dec 20 - Thu, Jan 21
United Airlines Logo
1:10 am - 12:58 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
26h 48m1 stop Houston George Bush Intcntl
United Airlines Logo
12:45 am - 10:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
18h 25m1 stop Houston George Bush Intcntl
$709United Airlines
Sun, Dec 13 - Tue, Dec 29
United Airlines Logo
10:40 am - 12:45 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
17h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
6:35 pm - 10:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
24h 35m1 stop Houston George Bush Intcntl
$709United Airlines
Sun, Apr 11 - Sat, May 1
Avianca Logo
2:10 pm - 10:35 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
10h 25m1 stop San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 1:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
11h 15m1 stop San Salvador El Salvador Intl
$710Avianca
Tue, Feb 9 - Fri, Feb 26
Avianca Logo
2:10 pm - 9:40 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
10h 30m1 stop San Salvador El Salvador Intl
Avianca Logo
11:00 pm - 1:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
11h 10m1 stop San Salvador El Salvador Intl
$712Avianca
Thu, Mar 18 - Mon, Mar 29
Copa Airlines Logo
6:46 am - 11:40 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
18h 54m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:55 pm - 8:35 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
22h 40m1 stop Panama City Tocumen Intl
$718Copa Airlines
Thu, Jan 21 - Wed, Jan 27
Copa Airlines Logo
10:45 am - 11:15 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
15h 30m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:40 am - 2:15 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
10h 35m1 stop Panama City Tocumen Intl
$718Copa Airlines
Booking Insights

Price, demand and travel trends for Medellín Jose Maria Cordova Intl Airport to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

Round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco typically range from $519 to $791. The lowest price found in the past 5 days was $539, on Frontier.

What's the cheapest day of the week to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco. It’s 26% cheaper than the average day, while Monday is the most expensive, with prices 18% higher.

What’s the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

•February is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco at $487 round-trip.
•August ($842) and November ($811) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 72% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Medellín Jose Maria Cordova Intl Airport to San Francisco the cheapest?

Flights from Medellín Jose Maria Cordova Intl Airport to San Francisco are cheapest 10 weeks before departure. Booking in this window typically costs about 32% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Medellín Jose Maria Cordova Intl Airport to San Francisco flights

Low season

September

Cheapest flight

$315
Beat the crowds with an average 42% drop in travelers.
The most popular month to fly with an average 36% increase in travelers.
One-way flight from Medellín Jose Maria Cordova Intl Airport to San Francisco

When to book flights from Medellín to San Francisco

Are your dates flexible? Find out the best times to travel from Medellín to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Medellín Jose Maria Cordova Intl Airport to San Francisco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Three cabin classes are available on flights from Medellín Jose Maria Cordova Intl Airport to San Francisco:

    • Economy Class
    • Premium Economy Class
    • Business Class

  • How long is a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    A nonstop flight from Medellín Jose Maria Cordova Intl Airport to San Francisco takes 00m, covering 3,653 miles.

  • Do I need a passport to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Medellín Jose Maria Cordova Intl Airport to San Francisco flight?

    Round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco range from $519 to $791, with an average of $678 over the past 12 months. Anything below $519 counts as a good deal.

  • How expensive are last-minute Medellín Jose Maria Cordova Intl Airport to San Francisco flights?

    Last-minute fares on this route (booked within two weeks of departure) run 1% above the $678 route average. Book 10 weeks before departure for the lowest fares.

  • Have flight prices from Medellín Jose Maria Cordova Intl Airport to San Francisco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $539 to $2,015. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Medellín Jose Maria Cordova Intl Airport to San Francisco looking right now?

    One-way fares from Medellín Jose Maria Cordova Intl Airport to San Francisco are currently in line with typical prices for this route. Average one-way fares are about $488.

  • What car rental options are available at San Francisco Airport (SFO)?

    San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include:

    • Europcar
    • Thrifty
    • Dollar
    • Hertz
    • Fox

  • Which airports can I use when flying from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Flights from Medellín Jose Maria Cordova Intl Airport to San Francisco usually depart from Medellín Jose Maria Cordova Intl (MDE) and arrive at San Francisco (SFO).

  • Which airports do connecting flights from Medellín Jose Maria Cordova Intl Airport to San Francisco pass through?

    One-stop flights from Medellín Jose Maria Cordova Intl Airport to San Francisco most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 49% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 25% of one-stop connections
    • San Salvador El Salvador Intl (SAL) - 18% of one-stop connections
    • Miami (MIA) - 7% of one-stop connections

  • Can I save money by using flexible dates for flights from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Yes. Flexible dates can save you up to 38% on flights from Medellín Jose Maria Cordova Intl Airport to San Francisco. Wednesday is the cheapest departure day at $502 round-trip on average, while Monday is the most expensive at $802, a difference of $300.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time at 11h 05m, compared with 11h 08m via Panama City Tocumen Intl (PTY) and 13h 07m via Miami (MIA).

  • What is the time difference between Medellín Jose Maria Cordova Intl Airport and San Francisco?

    San Francisco is 3 hours behind Medellín Jose Maria Cordova Intl Airport (Pacific Time vs Colombia Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Francisco?

    Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Your guide to booking Medellín Jose Maria Cordova Intl Airport to San Francisco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $502, about $300 less than Monday fares (37% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 10 weeks before you fly. On this route, that window historically saves about 32% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Medellín Jose Maria Cordova Intl Airport to San Francisco trip for February. Fares historically average $487 round-trip in that month - typically $355 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

    • Grand Hyatt At Sfo

More options for your flight from Medellín to San Francisco

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