United States
USD

MDE - SFO

$290 Find Cheap Flights from Medellín to San Francisco - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$675
Typical prices: $500-$698
American Airlines
Mon 10/22Thu 10/25
MDE - SFO • 1 stop
Cheapest one-way
$290
Typical prices: $337-$547
Multiple Airlines
Fri 11/30
MDE - SFO • 3 stops
Nonstop flights
Not available
There are currently no direct flights between Medellín Jose Maria Cordova Intl Airport and San Francisco. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
10 weeks
in advance
Our data shows that travelers who book at least 10 weeks in advance save around 24% compared to booking last minute.
Insights
Insights
When to travel
February
Cheapest • 17% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
San Salvador El Salvador Intl (SAL)
Cheapest • Avg $574 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 10h 54m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to San Francisco (MDE-SFO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Francisco

Thu, Oct 22 - Sun, Oct 25
American Airlines Logo
1:50 pm - 11:59 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
12h 09m1 stop Miami
American Airlines Logo
9:46 pm - 8:15 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
20h 29m1 stop Miami
$675American Airlines
Mon, Oct 19 - Thu, Nov 5
American Airlines Logo
6:00 am - 9:59 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
17h 59m1 stop Miami
American Airlines Logo
11:47 pm - 11:34 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
20h 47m1 stop Miami
$675American Airlines
Thu, Oct 22 - Tue, Nov 3
American Airlines Logo
6:00 am - 9:59 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
17h 59m1 stop Miami
American Airlines Logo
6:38 am - 11:34 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
13h 56m2 stops Dallas/Fort Worth Miami
$680American Airlines
Thu, Oct 22 - Tue, Nov 3
American Airlines Logo
6:00 am - 11:06 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
19h 06m2 stops Miami Dallas/Fort Worth
American Airlines Logo
7:00 am - 11:34 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
13h 34m2 stops Los Angeles Miami
$680American Airlines
Thu, Nov 26 - Tue, Feb 16
Copa Airlines Logo
10:45 am - 11:12 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
15h 27m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:36 pm - 10:55 amSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
12h 19m1 stop Panama City Tocumen Intl
$703Copa Airlines
Thu, Oct 15 - Fri, Oct 23
United Airlines Logo
9:45 am - 10:42 amMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
26h 57m1 stop Houston George Bush Intcntl
United Airlines Logo
5:10 pm - 9:05 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
25h 55m1 stop Houston George Bush Intcntl
$703United Airlines
Wed, Oct 28 - Thu, Nov 12
United Airlines Logo
9:45 am - 9:46 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
14h 01m1 stop Houston George Bush Intcntl
United Airlines Logo
2:30 pm - 10:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
28h 40m1 stop Houston George Bush Intcntl
$703United Airlines
Thu, Oct 15 - Sun, Oct 25
Copa Airlines Logo
5:00 am - 11:40 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
20h 40m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:36 pm - 8:15 amSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
9h 39m1 stop Panama City Tocumen Intl
$704Copa Airlines
Wed, Mar 17 - Tue, Mar 23
Copa Airlines Logo
5:00 am - 11:40 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
20h 40m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:55 pm - 10:55 amSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
13h 00m1 stop Panama City Tocumen Intl
$704Copa Airlines
Thu, Mar 11 - Tue, Apr 6
United Airlines Logo
10:45 am - 2:50 pmMDE  Medellín Jose Maria Cordova Intl-SFO San Francisco
31h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
4:45 pm - 9:10 pmSFO  San Francisco-MDE Medellín Jose Maria Cordova Intl
26h 25m1 stop Houston George Bush Intcntl
$705United Airlines
Booking Insights

Price, demand and travel trends for Medellín Jose Maria Cordova Intl Airport to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

Round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco typically range from $500 to $698. The lowest price found in the past 5 days was $675, on American Airlines.

What's the cheapest day of the week to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco. It’s 16% cheaper than the average day, while Friday is the most expensive, with prices 16% higher.

What’s the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

•February is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco at $487 round-trip.
•June ($760) and July ($676) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 56% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Medellín Jose Maria Cordova Intl Airport to San Francisco the cheapest?

Flights from Medellín Jose Maria Cordova Intl Airport to San Francisco are cheapest 10 weeks before departure. Booking in this window typically costs about 24% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Medellín Jose Maria Cordova Intl Airport to San Francisco flights

Low season

September

Cheapest flight

$290
Beat the crowds with an average 34% drop in travelers.
The most popular month to fly with an average 29% increase in travelers.
One-way flight from Medellín Jose Maria Cordova Intl Airport to San Francisco

When to book flights from Medellín to San Francisco

Are your dates flexible? Find out the best times to travel from Medellín to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Medellín Jose Maria Cordova Intl Airport to San Francisco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Four cabin classes are available on flights from Medellín Jose Maria Cordova Intl Airport to San Francisco:

    • Economy Class
    • Premium Economy Class
    • Business Class
    • First Class

    Prices vary by airline.

  • How long is a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    A nonstop flight from Medellín Jose Maria Cordova Intl Airport to San Francisco takes 00m, covering 3,653 miles.

  • Do I need a passport to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Medellín Jose Maria Cordova Intl Airport to San Francisco flight?

    Round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco range from $500 to $698, with an average of $584 over the past 12 months. Anything below $500 counts as a good deal.

  • How expensive are last-minute Medellín Jose Maria Cordova Intl Airport to San Francisco flights?

    Last-minute fares on this route (booked within two weeks of departure) run 1% above the $584 route average. Book 10 weeks before departure for the lowest fares.

  • Have flight prices from Medellín Jose Maria Cordova Intl Airport to San Francisco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $675 to $1,960. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Medellín Jose Maria Cordova Intl Airport to San Francisco looking right now?

    One-way fares from Medellín Jose Maria Cordova Intl Airport to San Francisco are currently in line with typical prices for this route. Average one-way fares are about $416.

  • What car rental options are available at San Francisco Airport (SFO)?

    San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates starting from around $15 for economy cars. Top options include:

    • Thrifty
    • Europcar
    • Dollar
    • Hertz
    • Fox

  • Which airports can I use when flying from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Flights from Medellín Jose Maria Cordova Intl Airport to San Francisco usually depart from Medellín Jose Maria Cordova Intl (MDE) and arrive at San Francisco (SFO).

  • Which airports do connecting flights from Medellín Jose Maria Cordova Intl Airport to San Francisco pass through?

    One-stop flights from Medellín Jose Maria Cordova Intl Airport to San Francisco most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 43% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 29% of one-stop connections
    • San Salvador El Salvador Intl (SAL) - 18% of one-stop connections
    • Miami (MIA) - 7% of one-stop connections

  • Can I save money by using flexible dates for flights from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Yes. Flexible dates can save you up to 28% on flights from Medellín Jose Maria Cordova Intl Airport to San Francisco. Wednesday is the cheapest departure day at $495 round-trip on average, while Friday is the most expensive at $679, a difference of $184.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time at 10h 53m, compared with 10h 54m via Panama City Tocumen Intl (PTY) and 13h 10m via Miami (MIA).

  • What is the time difference between Medellín Jose Maria Cordova Intl Airport and San Francisco?

    San Francisco is 2 hours behind Medellín Jose Maria Cordova Intl Airport (Pacific Time vs Colombia Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Francisco?

    Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Your guide to booking Medellín Jose Maria Cordova Intl Airport to San Francisco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Friday. On this route, Wednesday flights average $495, about $184 less than Friday fares (27% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 10 weeks before you fly. On this route, that window historically saves about 24% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Medellín Jose Maria Cordova Intl Airport to San Francisco trip for February. Fares historically average $487 round-trip in that month - typically $273 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

    • Grand Hyatt At Sfo

More options for your flight from Medellín to San Francisco

Complete your trip to San Francisco with a hotel stay or car rental

Car rentals in San Francisco
Hotels in San Francisco
Vacations in San Francisco