MDE - SFO

$254 Find Cheap Flights from Medellín to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$471
Overall average: $675
Copa Airlines
Tue 11/18Thu 12/4
MDE - SFO • 1 stop
Cheapest one-way
$254
Typical prices: $342-$521
Multiple Airlines
Thu 12/4
MDE - SFO • 2 stops
Top airlines
Copa Airlines
Cheapest • from $471 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
May
Cheapest • 8% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to San Francisco (MDE-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Francisco

Tue, Nov 18 - Thu, Dec 4
Copa Airlines Logo
6:24 am - 11:17 pmMDE-SFO
19h 53m1 stop
Copa Airlines Logo
12:36 am - 2:15 pmSFO-MDE
10h 39m1 stop
$471Copa Airlines
Find Deal
Wed, Dec 3 - Thu, Dec 11
United Airlines Logo
1:15 am - 12:09 pmMDE-SFO
13h 54m1 stop
United Airlines Logo
7:10 pm - 10:05 pmSFO-MDE
23h 55m1 stop
$474United Airlines
Find Deal
Tue, Dec 9 - Sat, Dec 13
United Airlines Logo
10:45 am - 9:05 pmMDE-SFO
13h 20m1 stop
United Airlines Logo
7:10 pm - 5:42 amSFO-MDE
31h 32m1 stop
$475United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 18
American Airlines Logo
12:20 am - 2:12 pmMDE-SFO
15h 52m2 stops
American Airlines Logo
5:00 am - 10:15 pmSFO-MDE
15h 15m2 stops
$526American Airlines
Find Deal
Tue, Mar 10 - Sun, Mar 15
LATAM Airlines Logo
9:45 am - 10:35 amMDE-SFO
26h 50m2 stops
LATAM Airlines Logo
11:55 pm - 9:20 pmSFO-MDE
19h 25m2 stops
$528LATAM Airlines
Find Deal
Thu, Dec 4 - Wed, Dec 10
Copa Airlines Logo
12:42 pm - 11:17 pmMDE-SFO
13h 35m1 stop
Copa Airlines Logo
12:36 am - 2:45 pmSFO-MDE
11h 09m1 stop
$534Copa Airlines
Find Deal
Mon, Mar 30 - Sun, Apr 19
Avianca Logo
3:15 am - 12:35 pmMDE-SFO
11h 20m1 stop
Avianca Logo
2:20 pm - 2:05 amSFO-MDE
9h 45m1 stop
$538Avianca
Find Deal
Mon, Mar 30 - Sun, Apr 19
Avianca Logo
3:15 am - 12:35 pmMDE-SFO
11h 20m1 stop
Avianca Logo
2:20 pm - 2:05 amSFO-MDE
9h 45m1 stop
$540Avianca
Find Deal
Mon, Mar 30 - Sat, Apr 18
American Airlines Logo
12:20 am - 3:46 pmMDE-SFO
17h 26m2 stops
American Airlines Logo
12:21 am - 7:50 pmSFO-MDE
17h 29m2 stops
$558American Airlines
Find Deal
Wed, Mar 11 - Mon, Mar 16
LATAM Airlines Logo
6:00 am - 9:46 pmMDE-SFO
17h 46m2 stops
LATAM Airlines Logo
11:55 pm - 9:20 pmSFO-MDE
19h 25m2 stops
$567LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Medellín to San Francisco flights

Get data-powered insights and trends into flights from Medellín to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to San Francisco?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to San Francisco, you should consider leaving on a Thursday and avoid Mondays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Mondays and the most expensive ones on Thursdays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to San Francisco is May, where tickets cost $528 (return) on average. On the other hand, the most expensive months are December and November, where the average cost of round-trip tickets is $697 and $675 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to San Francisco, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$254
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 21% increase in price.
Flight from Medellín to San Francisco

When to book flights from Medellín to San Francisco

Are your dates flexible? Find out the best times to travel from Medellín to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to San Francisco flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco was $254 for a one-way ticket and $471 for a round-trip.

  • Do I need a passport to fly between Medellín and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Medellín to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medellín to San Francisco?

    Star Alliance is the only airline alliance operating flights between Medellín and San Francisco.

  • Which is the best airline for flights from Medellín to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $552 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $596 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Medellín to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Medellín with another airline. Booking your flights between Medellín and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Medellín to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Medellín to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1561 reviews
6.9Food
7.4Comfort
8.1Crew
6.8Entertainment
7.8Boarding
Airline reviews

Some of the Air hostesses are not that friendly. Need improvement

8.0 ExcellentAnonymous, Oct 2025PTY - IAD
Read more Copa Airlines reviews

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

7 hours delayed due to operational issues on United’s end. Basically laziness.

Flight from Rome to SFO was excellent compared To our flight to Europe from SFO. The food was much tastier. You can see how UNITED is skimping, though. Instead of getting something mid flight you had to ask for it. It was not automatically served. There was a cookie at the end of the arrival meal, for example that tasted like it just came out of a box. They used to serve a little container of nuts, now … a tiny container of nuts, mixed with pretzels. This was business class that you really have to pay for! But this is minor complaints compared to the overall. My major complaint is the position of the even numbered seats by the windows. You have to turn around to see your window & the positioning as some other controls are harder to get at. This is compared to the odd number seat that are perfectly aligned.

The food quality sucks. One must starve if they do not eat flesh Or wheat based products Some variety would be expected. The trivial amount of snacks and or food is inhumane

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

1. when we went to check in, our 2 first class seats had been CANCELED and the flight was sold out. This was done without our prior knowledge. It was all we could do to restore one first class seat for my wife and I flew economy. 2, Our flight home was scheduled to leave at 10:30 pm. Due to tsunami warnings, the roads were closed and our flight status was uncertain as to whether it would leave as scheduled. It was announced that it would now leave at 11:20 pm and the roads were now open since the tsunami had come and gone. We made a mad dash to the airport and checked in. Delays were announced at 12:30 pm, 1:30 am, 2:30 am and at 3:30 am it was canceled. Since this was a flight due to natural (tsunami) causes, there was no compensation. We were told to return at 1:00 pm the next day and our baggage would be kept on the plane since the same plane was going to leave at 1:00 pm. We had to return to our hotel for the rest of the night. The same plane did not leave at 1:00 pm and our baggage was gone! All in all, it was a miserable performance by UA. Information was hard to obtain and no one knew what was going on and what was going to happen. Hundreds of passengers slept on the floor, chairs, etc. No food and no water was made available to the passengers. It was a situation where UA could care less what was going on. As a one million mile flyer, I had not experienced anything like this before and it was hugely disappointing!

I found the staff to not be very attentive at all. When paying for Business Class you expect a certain type of service and that was not found. They were almost rude even

Our experience on United Airlines was extremely poor. The plane was extremely cold throughout our entire flight- which multiple people complained about- and we had to wait 2 hours to get a blanket which was too thin and barely helped warm us up. As well as this, none of the entertainment features were working so we had to sit through a roughly 10 hour flight with nothing to keep our attention, including the actual flight path screen. It was an extremely disappointing experience and I would hope that this gets fixed if we ever choose United Airlines again.

I really enjoyed flying with United airlines amazing experience , good customer service and great food

1.It will be better if sandwich is warm. 2.The food is too salty. 3.Breakfast needs some vegetables or fruits.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

Avianca is not what it used to be. So disappointing

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

Everything you need to know for your flight from Medellín to San Francisco

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