MDE - SFO

$240 Find Cheap Flights from Medellín to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to San Francisco (MDE-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Francisco

Mon, Nov 10 - Tue, Nov 18
American Airlines Logo
1:30 am - 1:29 pmMDE-SFO
14h 59m2 stops
American Airlines Logo
7:10 am - 11:39 pmSFO-MDE
13h 29m2 stops
$533American Airlines
Find Deal
Mon, Mar 30 - Sun, Apr 19
Avianca Logo
3:15 am - 12:35 pmMDE-SFO
11h 20m1 stop
Avianca Logo
2:20 pm - 2:05 amSFO-MDE
9h 45m1 stop
$543Avianca
Find Deal
Mon, Mar 30 - Sun, Apr 19
Avianca Logo
3:15 am - 12:35 pmMDE-SFO
11h 20m1 stop
Avianca Logo
2:20 pm - 2:05 amSFO-MDE
9h 45m1 stop
$546Avianca
Find Deal
Sat, Nov 22 - Mon, Jan 12
Multiple Airlines Logo
5:00 am - 8:47 pmMDE-SFO
18h 47m2 stops
Multiple Airlines Logo
11:10 pm - 12:55 pmSFO-MDE
10h 45m1 stop
$547Multiple Airlines
Find Deal
Tue, Nov 11 - Mon, Nov 17
Copa Airlines Logo
8:37 am - 11:17 pmMDE-SFO
17h 40m1 stop
Copa Airlines Logo
12:36 am - 2:45 pmSFO-MDE
11h 09m1 stop
$549Copa Airlines
Find Deal
Fri, Dec 19 - Fri, Jan 2
United Airlines Logo
10:45 am - 12:21 amMDE-SFO
16h 36m1 stop
United Airlines Logo
11:59 pm - 5:42 amSFO-MDE
26h 43m1 stop
$557United Airlines
Find Deal
Fri, Dec 19 - Wed, Dec 31
United Airlines Logo
10:45 am - 12:21 amMDE-SFO
16h 36m1 stop
United Airlines Logo
2:57 pm - 5:42 amSFO-MDE
11h 45m1 stop
$560United Airlines
Find Deal
Sat, Dec 6 - Thu, Jan 8
Multiple Airlines Logo
2:10 pm - 9:50 pmMDE-SFO
10h 40m1 stop
Multiple Airlines Logo
3:20 pm - 12:55 pmSFO-MDE
18h 35m2 stops
$569Multiple Airlines
Find Deal
Tue, Mar 31 - Sat, Apr 18
Copa Airlines Logo
10:46 am - 11:40 pmMDE-SFO
14h 54m1 stop
Copa Airlines Logo
1:42 am - 8:35 pmSFO-MDE
16h 53m1 stop
$610Copa Airlines
Find Deal
Fri, Feb 20 - Sat, Feb 21
Aeromexico Logo
12:45 am - 11:51 amMDE-SFO
14h 06m1 stop
Aeromexico Logo
10:30 pm - 11:10 pmSFO-MDE
21h 40m1 stop
$665Aeromexico
Find Deal

Everything you should know

Top airlines
American Airlines
Cheapest • from $533 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
May
Cheapest • 8% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$533
Overall average: $685
American Airlines
Mon 11/10Tue 11/18
MDE - SFO • 2 stops
Cheapest one-way
$240
Typical prices: $316-$356
Multiple Airlines
Fri 11/7
MDE - SFO • 2 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Booking Insights

KAYAK's insights & trends for Medellín to San Francisco flights

Get data-powered insights and trends into flights from Medellín to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to San Francisco?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to San Francisco, you should consider leaving on a Thursday and avoid Mondays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Mondays and the most expensive ones on Thursdays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to San Francisco is May, where tickets cost $528 (return) on average. On the other hand, the most expensive months are December and November, where the average cost of round-trip tickets is $697 and $685 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to San Francisco, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$240
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 21% increase in price.
Flight from Medellín to San Francisco

When to book flights from Medellín to San Francisco

Are your dates flexible? Find out the best times to travel from Medellín to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to San Francisco flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco was $240 for a one-way ticket and $533 for a round-trip.

  • Do I need a passport to fly between Medellín and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Medellín to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medellín to San Francisco?

    oneworld, and Star Alliance are the airline alliances operating flights between Medellín and San Francisco, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Medellín to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $561 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $596 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Medellín to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Medellín with another airline. Booking your flights between Medellín and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Medellín to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Medellín to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1557 reviews
7.4Comfort
7.8Boarding
6.8Entertainment
8.1Crew
6.8Food
Airline reviews

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

10.0 ExcellentMichael, Sep 2025PBM - PTY
Read more Copa Airlines reviews

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

The food quality sucks. One must starve if they do not eat flesh Or wheat based products Some variety would be expected. The trivial amount of snacks and or food is inhumane

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

1. when we went to check in, our 2 first class seats had been CANCELED and the flight was sold out. This was done without our prior knowledge. It was all we could do to restore one first class seat for my wife and I flew economy. 2, Our flight home was scheduled to leave at 10:30 pm. Due to tsunami warnings, the roads were closed and our flight status was uncertain as to whether it would leave as scheduled. It was announced that it would now leave at 11:20 pm and the roads were now open since the tsunami had come and gone. We made a mad dash to the airport and checked in. Delays were announced at 12:30 pm, 1:30 am, 2:30 am and at 3:30 am it was canceled. Since this was a flight due to natural (tsunami) causes, there was no compensation. We were told to return at 1:00 pm the next day and our baggage would be kept on the plane since the same plane was going to leave at 1:00 pm. We had to return to our hotel for the rest of the night. The same plane did not leave at 1:00 pm and our baggage was gone! All in all, it was a miserable performance by UA. Information was hard to obtain and no one knew what was going on and what was going to happen. Hundreds of passengers slept on the floor, chairs, etc. No food and no water was made available to the passengers. It was a situation where UA could care less what was going on. As a one million mile flyer, I had not experienced anything like this before and it was hugely disappointing!

I found the staff to not be very attentive at all. When paying for Business Class you expect a certain type of service and that was not found. They were almost rude even

Our experience on United Airlines was extremely poor. The plane was extremely cold throughout our entire flight- which multiple people complained about- and we had to wait 2 hours to get a blanket which was too thin and barely helped warm us up. As well as this, none of the entertainment features were working so we had to sit through a roughly 10 hour flight with nothing to keep our attention, including the actual flight path screen. It was an extremely disappointing experience and I would hope that this gets fixed if we ever choose United Airlines again.

I really enjoyed flying with United airlines amazing experience , good customer service and great food

1.It will be better if sandwich is warm. 2.The food is too salty. 3.Breakfast needs some vegetables or fruits.

Boarded plane and then delayed 1.5 hours while on the plane

It was all good flight was on time, service was good I enjoyed a few movies and everything was smooth

The business class seats are dated and uncomfortable. The space is bare minimum and there is absolutely no privacy. For $4K, this is not what I expect.

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

American Airlines is a mediocre airlines: they do not maintain the highest standard of cleanliness in the cabins, and the food is not well thought out. Service is not at top of mind compared to other international airlines such as Singapore Airlines, JAL or others.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

Avianca is not what it used to be. So disappointing

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Everything you need to know for your flight from Medellín to San Francisco

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.