MDE - SFO

$270 Find Cheap Flights from Medellín to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to San Francisco (MDE-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Francisco

Wed, Oct 22 - Mon, Nov 3
JetBlue Logo
1:30 pm - 11:16 pmMDE-SFO
11h 46m1 stop
JetBlue Logo
9:44 pm - 2:32 pmSFO-MDE
13h 48m1 stop
$431JetBlue
Find Deal
Sat, Nov 1 - Sat, Nov 8
JetBlue Logo
1:10 pm - 11:31 pmMDE-SFO
12h 21m1 stop
JetBlue Logo
9:45 pm - 2:32 pmSFO-MDE
13h 47m1 stop
$432JetBlue
Find Deal
Tue, Sep 9 - Sun, Oct 19
Avianca Logo
2:10 pm - 10:45 pmMDE-SFO
10h 35m1 stop
Avianca Logo
12:05 am - 12:40 pmSFO-MDE
10h 35m1 stop
$484Avianca
Find Deal
Tue, Sep 9 - Sun, Sep 14
Avianca Logo
2:10 pm - 10:45 pmMDE-SFO
10h 35m1 stop
Avianca Logo
12:05 am - 6:01 pmSFO-MDE
15h 56m2 stops
$489Avianca
Find Deal
Fri, Oct 3 - Mon, Nov 3
American Airlines Logo
6:00 am - 10:54 pmMDE-SFO
18h 54m1 stop
American Airlines Logo
7:00 am - 11:39 pmSFO-MDE
13h 39m2 stops
$526American Airlines
Find Deal
Mon, Sep 8 - Wed, Oct 8
American Airlines Logo
6:00 am - 10:54 pmMDE-SFO
18h 54m1 stop
American Airlines Logo
8:00 am - 8:15 pmSFO-MDE
10h 15m1 stop
$528American Airlines
Find Deal
Tue, Sep 9 - Sun, Sep 14
Copa Airlines Logo
10:46 am - 11:25 pmMDE-SFO
14h 39m1 stop
Copa Airlines Logo
1:30 am - 10:51 pmSFO-MDE
19h 21m1 stop
$539Copa Airlines
Find Deal
Thu, Nov 20 - Sun, Dec 7
United Airlines Logo
10:45 am - 12:12 amMDE-SFO
16h 27m1 stop
United Airlines Logo
12:43 am - 5:42 amSFO-MDE
25h 59m1 stop
$543United Airlines
Find Deal
Thu, Nov 20 - Fri, Jan 2
United Airlines Logo
10:45 am - 7:35 amMDE-SFO
23h 50m1 stop
United Airlines Logo
2:57 pm - 5:42 amSFO-MDE
11h 45m1 stop
$548United Airlines
Find Deal
Mon, Sep 8 - Sun, Oct 19
Copa Airlines Logo
6:18 pm - 11:25 pmMDE-SFO
31h 07m1 stop
Copa Airlines Logo
1:31 am - 2:15 pmSFO-MDE
10h 44m1 stop
$563Copa Airlines
Find Deal

Everything you should know

Top airlines
JetBlue
Cheapest • from $431 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
2 weeks
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 6% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 8% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$431
Overall average: $544
JetBlue
Wed 10/22Mon 11/3
MDE - SFO • 1 stop
Cheapest one-way
$270
Typical prices: $316-399
JetBlue
Wed 11/5
MDE - SFO • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Booking Insights

KAYAK's insights & trends for Medellín to San Francisco flights

Get data-powered insights and trends into flights from Medellín to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to San Francisco?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to San Francisco, you should consider leaving on a Thursday and avoid Mondays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Mondays and the most expensive ones on Thursdays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to San Francisco is May, where tickets cost $528 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $667 and $653 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to San Francisco, you should book around 2 weeks before departure, which saves you about 6% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$270
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 16% increase in price.
Flight from Medellín to San Francisco

When to book flights from Medellín to San Francisco

Are your dates flexible? Find out the best times to travel from Medellín to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to San Francisco flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco was $270 for a one-way ticket and $431 for a round-trip.

  • Do I need a passport to fly between Medellín and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Medellín to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medellín to San Francisco?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Medellín and San Francisco, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Medellín to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $589 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $621 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Medellín to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Medellín with another airline. Booking your flights between Medellín and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Medellín to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Medellín to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1526 reviews
6.8Food
6.8Entertainment
8.1Crew
7.8Boarding
7.4Comfort
Airline reviews

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

10.0 ExcellentAnonymous, Aug 2025CTG - PTY
Read more Copa Airlines reviews

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

1. when we went to check in, our 2 first class seats had been CANCELED and the flight was sold out. This was done without our prior knowledge. It was all we could do to restore one first class seat for my wife and I flew economy. 2, Our flight home was scheduled to leave at 10:30 pm. Due to tsunami warnings, the roads were closed and our flight status was uncertain as to whether it would leave as scheduled. It was announced that it would now leave at 11:20 pm and the roads were now open since the tsunami had come and gone. We made a mad dash to the airport and checked in. Delays were announced at 12:30 pm, 1:30 am, 2:30 am and at 3:30 am it was canceled. Since this was a flight due to natural (tsunami) causes, there was no compensation. We were told to return at 1:00 pm the next day and our baggage would be kept on the plane since the same plane was going to leave at 1:00 pm. We had to return to our hotel for the rest of the night. The same plane did not leave at 1:00 pm and our baggage was gone! All in all, it was a miserable performance by UA. Information was hard to obtain and no one knew what was going on and what was going to happen. Hundreds of passengers slept on the floor, chairs, etc. No food and no water was made available to the passengers. It was a situation where UA could care less what was going on. As a one million mile flyer, I had not experienced anything like this before and it was hugely disappointing!

I found the staff to not be very attentive at all. When paying for Business Class you expect a certain type of service and that was not found. They were almost rude even

Our experience on United Airlines was extremely poor. The plane was extremely cold throughout our entire flight- which multiple people complained about- and we had to wait 2 hours to get a blanket which was too thin and barely helped warm us up. As well as this, none of the entertainment features were working so we had to sit through a roughly 10 hour flight with nothing to keep our attention, including the actual flight path screen. It was an extremely disappointing experience and I would hope that this gets fixed if we ever choose United Airlines again.

I really enjoyed flying with United airlines amazing experience , good customer service and great food

1.It will be better if sandwich is warm. 2.The food is too salty. 3.Breakfast needs some vegetables or fruits.

Boarded plane and then delayed 1.5 hours while on the plane

It was all good flight was on time, service was good I enjoyed a few movies and everything was smooth

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

Really good 😊 the woman at the gate entrance was a little rude checking in our carry-on but i dont think she worked for the airline, she worked for the airport at sacramento, other than that amazing.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

American Airlines is a mediocre airlines: they do not maintain the highest standard of cleanliness in the cabins, and the food is not well thought out. Service is not at top of mind compared to other international airlines such as Singapore Airlines, JAL or others.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

Avianca is not what it used to be. So disappointing

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Everything you need to know for your flight from Medellín to San Francisco

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.