MDE - SFO

$228 Find Cheap Flights from Medellín to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to San Francisco departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$394
Typical prices: $555-$469
Avianca
Fri 5/22Sat 5/30
MDE - SFO • 1 stop
Cheapest one-way
$228
Typical prices: $288-$344
American Airlines
Fri 5/8
MDE - SFO • 1 stop
Top airlines
Cheapest • from $394 (round-trip)
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medellín and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $607 (round-trip)
Shortest trip • 11h 10m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 2 weeks in advance save around 15% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 11% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to San Francisco (MDE-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Francisco

Fri, May 22 - Sat, May 30
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$394Avianca
Fri, May 22 - Sat, May 30
Avianca Logo
9:55 am - 10:35 pm
MDE
-
SFO
14h 40m
2 stops
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$399Avianca
Fri, May 8 - Mon, May 11
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$412Avianca
Fri, May 8 - Mon, May 11
Avianca Logo
2:10 pm - 10:35 pm
MDE
-
SFO
10h 25m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$413Avianca
Sun, Apr 26 - Sun, May 3
Avianca Logo
3:05 pm - 12:50 pm
MDE
-
SFO
23h 45m
2 stops
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$420Avianca
Fri, May 8 - Mon, May 11
Avianca Logo
9:55 am - 12:50 pm
MDE
-
SFO
28h 55m
2 stops
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$422Avianca
Sun, Apr 26 - Sun, May 3
Avianca Logo
2:10 pm - 12:50 pm
MDE
-
SFO
24h 40m
1 stop
Avianca Logo
11:55 pm - 1:10 pm
SFO
-
MDE
11h 15m
1 stop
$428Avianca
Wed, Apr 22 - Sat, Apr 25
Avianca Logo
6:20 am - 10:35 pm
MDE
-
SFO
18h 15m
2 stops
Avianca Logo
2:30 am - 6:40 pm
SFO
-
MDE
14h 10m
2 stops
$431Avianca
Fri, May 8 - Mon, May 11
Avianca Logo
10:45 pm - 12:50 pm
MDE
-
SFO
16h 05m
2 stops
Avianca Logo
11:55 pm - 11:35 pm
SFO
-
MDE
21h 40m
2 stops
$432Avianca
Fri, May 8 - Mon, May 11
Avianca Logo
7:40 am - 10:35 pm
MDE
-
SFO
16h 55m
2 stops
Avianca Logo
11:55 pm - 6:55 pm
SFO
-
MDE
17h 00m
2 stops
$433Avianca
Booking Insights

KAYAK's insights & trends for Medellín to San Francisco flights

Get data-powered insights and trends into flights from Medellín to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco departing in May.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to San Francisco is February, where tickets cost $487 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $662 and $647 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to San Francisco, you should book around 2 weeks before departure, which saves you about 15% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$228
Best time to beat the crowds but there is an average 18% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Medellín to San Francisco

When to book flights from Medellín to San Francisco

Are your dates flexible? Find out the best times to travel from Medellín to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to San Francisco flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco was $228 for a one-way ticket and $394 for a round-trip.

  • Do I need a passport to fly between Medellín and San Francisco?

    Yes

  • Which aircraft models fly most regularly from Medellín to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medellín to San Francisco?

    Star Alliance is the only airline alliance operating flights between Medellín and San Francisco.

  • Which is the best airline for flights from Medellín to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $540 and an overall rating of 7.5, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $579 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Medellín to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Medellín with another airline. Booking your flights between Medellín and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Medellín to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Medellín to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1579 reviews
6.8Food
7.4Comfort
6.8Entertainment
7.8Boarding
8.1Crew
Airline reviews

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

2.0 MediocreEdwin, Mar 2026
LIM - PTY
Read more Copa Airlines reviews

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

We got to get extended leg room in Econ plus that was great. It was nice having our own dietary needs met with our meals, and the connecting flights had it as well. Only negative were the seats my bottom was/is really sore after a ten plus hour flight. Those seats are horrible, understandable for as many people use them. So we are going to purchase a gel seat pad.

Flight to Japan was was better across the board than the return to USA. Entertainment: Movie selection was old and not to my liking. Way too many woke choices. Not enough selections for sports or drama. Service: some of the crew were great. Not all. I paid for business class. a premium. Some of the crew thought they 'had' t do there job instead of wanting to serve and be polite. Food: Way to Japan was good. Way back to USA bad. Boarding: Wat out did not offer Business only; had to go thru general. If you pay for business, you should get business perks. Suggest you look for other than United for travel to Asia

I will never fly ANA again. They lost one of my large pieces of checked luggage, the heaviest one with the most valuable items in it, and they said they will not send me an email unless they can't find it, even though the paper they gave me to track the status of my lost luggage requires a code from an email they are supposed to send me so I can do baggage tracing. They claim to be an international airline, but they also insist on calling a Japanese telephone number to confirm where to send the lost baggage if they find it. It is impossible to find an actual contact email address for customer support on their website, and their AI chatbot is unhelpful, directing you to a webpage that says it is for contact information but does not have any actual email addresses or phone numbers listed on it. My seat in economy did not recline at all, even though I was not sitting in an exit row nor the very back row. I had to sit in the fully upright position for over ten hours of international travel. Awful experience overall.

The head flight attendant made the trip excellent. He was very accommodating.

The economy seats on the 777 was not as cramped as I had feared, but the food was terrible.

Terrible experience! delay 2 time and say i dont have ticket

Flight attendants were friendly & good service, food sucks, seats uncomfortable, not many Asian movies or shows flying from Hong Kong

Flight attendants had a little attitude. Food tastes no good.

Overall we had a good experience during our flight from San Francisco to Houston.

Good flight. However, when booked flight with United, assumed the layover included by United in San Francisco of 1 hr and 40 minutes was sufficient . Not so and would recommend at least 2 hours or more. Needed to go through US immigration (very long lineups), then pick up bags, take all the way to another terminal, running because we did not have sufficient time. We made the flight because they held the door for us but luggage didn’t follow.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

I upgraded to businesses class. Because of that the flight was comfortable.

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Everything you need to know for your flight from Medellín to San Francisco

Information on your arrival and departure airports