$309 Find Cheap Flights from South America to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from South America to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to San Francisco

Tue, Sep 15 - Tue, Sep 22
Multiple Airlines Logo
1:07 pm - 10:22 amBOG  Bogotá El Dorado-SFO San Francisco
23h 15m2 stops Guadalajara Miguel Hidal Los Angeles
Multiple Airlines Logo
6:00 am - 7:15 pmSFO  San Francisco-BOG Bogotá El Dorado
11h 15m1 stop Atlanta Hartsfield-Jackson
$600Multiple Airlines
Tue, Sep 22 - Mon, Oct 19
Avianca Logo
7:40 am - 11:55 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
20h 15m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
2:15 pm - 3:15 pmSFO  San Francisco-SCL Santiago Arturo Merino Benitez
21h 00m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$603Avianca
Sun, Sep 27 - Sun, Oct 4
Avianca Logo
7:40 am - 10:35 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 12:20 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
20h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$604Avianca
Tue, Sep 15 - Wed, Oct 21
Multiple Airlines Logo
1:07 pm - 10:22 amBOG  Bogotá El Dorado-SFO San Francisco
23h 15m2 stops Guadalajara Miguel Hidal Los Angeles
Multiple Airlines Logo
8:21 pm - 9:29 amSFO  San Francisco-BOG Bogotá El Dorado
11h 08m1 stop Panama City Tocumen Intl
$611Multiple Airlines
Wed, Sep 16 - Fri, Oct 16
American Airlines Logo
2:10 pm - 11:59 pmBOG  Bogotá El Dorado-SFO San Francisco
11h 49m1 stop Miami
American Airlines Logo
9:46 pm - 1:05 pmSFO  San Francisco-BOG Bogotá El Dorado
13h 19m1 stop Miami
$620American Airlines
Wed, Sep 9 - Wed, Sep 23
American Airlines Logo
2:10 pm - 11:59 pmBOG  Bogotá El Dorado-SFO San Francisco
11h 49m1 stop Miami
American Airlines Logo
9:00 am - 10:30 pmSFO  San Francisco-BOG Bogotá El Dorado
11h 30m1 stop Dallas/Fort Worth
$620American Airlines
Mon, Nov 9 - Thu, Nov 12
LATAM Airlines Logo
7:30 am - 9:23 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
18h 53m2 stops Lima J Chavez Intl Los Angeles
LATAM Airlines Logo
8:00 am - 7:00 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
18h 00m2 stops Atlanta Hartsfield-Jackson Miami
$638LATAM Airlines
Wed, Sep 30 - Thu, Oct 29
LATAM Airlines Logo
11:55 pm - 3:54 pmSCL  Santiago Arturo Merino Benitez-SFO San Francisco
19h 59m1 stop Los Angeles
LATAM Airlines Logo
8:00 am - 7:00 amSFO  San Francisco-SCL Santiago Arturo Merino Benitez
19h 00m2 stops Atlanta Hartsfield-Jackson Miami
$638LATAM Airlines
Tue, Oct 13 - Wed, Nov 4
United Airlines Logo
8:30 am - 7:24 pmBOG  Bogotá El Dorado-SFO San Francisco
12h 54m1 stop Houston George Bush Intcntl
United Airlines Logo
2:30 pm - 5:10 amSFO  San Francisco-BOG Bogotá El Dorado
11h 40m1 stop Houston George Bush Intcntl
$650United Airlines
Fri, Oct 16 - Wed, Nov 4
United Airlines Logo
12:14 am - 11:44 amBOG  Bogotá El Dorado-SFO San Francisco
13h 30m1 stop Houston George Bush Intcntl
United Airlines Logo
7:15 am - 10:35 pmSFO  San Francisco-BOG Bogotá El Dorado
12h 20m1 stop Houston George Bush Intcntl
$650United Airlines
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Good to know

Low season

February

Cheapest flight

$309
Best time to beat the crowds with an average 10% drop in price.
Flight from Santiago to San Francisco

FAQs for booking flights from South America to San Francisco

  • How does KAYAK find such low prices on flights from South America to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to San Francisco

 
Need help choosing which airline to fly with from South America to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1561 reviews
7.8Boarding
8.1Crew
7.4Comfort
6.8Entertainment
6.9Food
Airline reviews

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

10.0 ExcellentAnonymous, Aug 2026
Read more Copa Airlines reviews

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

I missed my original flight due to miscommunication and it was a challenge to communicate with service personnel, since my Portuguese is limited. However they got me food and a hotel overnight and a seat on the next available flight.

It was a bit unnerving to know that flights are generally oversold. We chose not to pay extra to reserve a specific seat, without realizing that that makes us vulnerable to being bumped. Everything else about the flight was great.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Plane never left the ground. Mech issues - entire trip was rerouted through united.

The seats are getting smaller and smaller. Very uncomfortable trip. More than in other airlines

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

Very courteous crew, the food was good and the flight was on time.

Our yoga retreat was cancelled and besides not refunding is, they would not even let us change dates or locations. As a matter of fact they wouldn’t even talk to us and kept referring to the travel agent, who said they couldn’t change anything and it was up to the airline to do so. They passed the buck until it was too late to do anything about it. Avoid Latham and Budget Air for your travel plans.

the seat has a problem. the back had a hole.

The entire experience convinced my wife, Cathy, and me that traveling Polaris on United is the only way we’ll fly in the future. From check-in and baggage drop to the end of the 12-hour flight, the customer service was exceptional, with numerous staff members exemplifying the very best in care. On board, Andre, our primary crew chief, was sincerely friendly, a consummate professional, and, along with Freddy, one of his team members, truly among the best of the best. The captain even came through the cabin to chat with passengers—a wonderful personal touch, especially on such a long journey.

The SFO lounge closes at 12 midnight. My flight took off at 2AM

Flight be on time would be a good start. Then train your flight attendants to be attentive and friendly. This time they completely forgot my row for the measly snack! United, do better!

We boarded the plane and were about to take off when we were notified that the tires had to be checked. Upon inspection, they were found to need replacement, so the entire plane had to be deboarded. After we exited the plane, United staff forced us to stay in the gate area by posting "Do Not Exit" signs on the doors connecting the gate area to the terminal. Many of us had already rebooked our flights and had no checked bags, but they told us we could not leave. This seemed inappropriate to hold people under false pretenses. When the agent told us we could leave, I asked them to please take down the "Do Not Exit" signs, as they were misleading. The agent refused, and I told them that it didn't feel right to hold people like that.

There was a piece of plastic baked into my buttermilk biscuit! I have a pictures. The flight attendants in first class were really apologetic, and tried to rectify the situation. I I am very appreciative that they were able to give me some packets of pretzels and gummy bears. I understand they don't personally handle the food until warming it up so I know it wasn't their fault. I don't know whether it was a newer aircraft, or different food packaging, but I was happy that when the food was being warmed up - it didn't smell like plastic. Jokes on me with finding plastic in my food.

United was excellent. We had very good experience flying the carrier. Certainly. We will opt to fly them for sure. Lufthansa is out.

The seat that I got this time is really good.

Excellent flight. On time. Great staff. Clean and crisp cabin.

The Manila airport was under renovation so there was no business class lounge. The double security check was disorganized and the flight attendants were grouchy.

Our experience with American Airlines was extremely disappointing and honestly made an already exhausting international journey much worse. After flying all the way from Melbourne and dealing with significant jet lag, the American Airlines experience at LAX was the last thing we needed. The terminal and boarding area felt very old and uncomfortable, with little to no air conditioning and only old fans running in the area. Boarding was also through outdoor stairs rather than a jet bridge, which felt especially inconvenient after such a long journey. Even though we were traveling First Class, the onboard experience was surprisingly poor. There were no meaningful snack options, no decent coffee available to order, and the aircraft was so small that there was barely enough overhead space for carry-on luggage. The staff experience was also disappointing and lacked the warmth or attentiveness we had experienced on our international flights. To make matters worse, the flight departed late, extending an already very long travel day. Overall, the combination of the outdated terminal, uncomfortable boarding process, limited First Class service, small aircraft, poor staff experience, and delay made this an extremely unpleasant final leg of our journey. It significantly worsened our exhaustion and jet lag rather than making the connection home easier. Unfortunately, this experience was bad enough that I do not plan to travel with American Airlines again in the future.

Horrible. No AC. No Air inside the plane. We had to deplane twice! It is late almost 5 hrs in total. I almost passed out and about to call 911. I asked the crew to be honest and open the door. The lady next to me was lay down in the floor due to heat and no air inside the plane. I got headaches, can’t wait the replacement flight about midnight Dallas time. I end it up rebook for next day flight and stay overnight using my own pocket in a hotel nearby due to headaches and can’t breath. I still have a headache this morning. Still not decided yes how to file this issue to AA and/or FAA.

I could not ask for more. Great service and experience.

Initial flight had an engine overheat - returned to DFW. Had another plane ready, but crew timed out. Had to wait 5h for boarding. Fully boarded and pilot says plane is not flight worthy. Deplane and go to the other end of the terminal. Wait an hour to board third plane because the crew couldn’t leave the second plane because no wheelchairs were brought to remove passengers. Finally take off and there is no catering (in flight service) even in first class. Very much an AA failure.

The food was good. I almost didn't get a seat on the flight unless I agreed to sit in emergency exit.

The flight attendant was very polite and attentive. The food was good.

I had a comfortable and enjoyable experience. The entertainment options were plentiful, the food was appetizing, the snacks were tasty, and the staff was friendly, professional, and helpful.

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

Buying ticket from kayak instant booking was a huge mistake, never to be repeated again! The Kayak didn’t book the tickets directly, it handed it off to a third party Underpricer, that booked a code shared American Airlines flight operated by Cathay Pacific!! When managing the booking American Airlines would recognize the itinerary but wouldn’t let me do anything stating, the flight is operated by Cathay Pacific so go to their website. Cathay Pacific would recognize the itinerary, neither by reservation ID or ticket number…asking to reach out to the third party Underpricer….calling Underpricer resulted in no help like seat requests, mileage number or upgrade request, 15hr layover accommodation voucher guidance…so net in net avoid booking through three layers of intermediaries

Better seats, allow us to upgrade, terrible website, poor telephone service, better equipment

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

The fees for baggage were outrageous. $130 for carry on and $150 for check in for an international flight. The seats did not recline. We were not even offered water. Had we known all of this, we would not have booked Avianca at all.

I was shocked flying to El Salvador that they only give you water. Everything else you have to pay for. There is no wifi or entertainment and it’s an international flight. At least back in the day they had tvs on the plane and everyone watched the same movie. Also seats do not recline, even comfort or plus.

I did not like anything, first time I use company and for sure it will be the last time, they charge for simple operations that any other average airline wouldn't charge.

The good thing is the flight was on time and the crew was really nice. They can work better the arriving with staff

The inflight entertainment did not work on a 6 hour flight The cel phone chargers did not work There was a 45 minute wait for the luggage to get off the plane.

They could offer free food and drink like other international flights.

Flight attendants to show up on time, offer drinks and food.

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