MEX - ECP

$497 Find Cheap Flights from Mexico City to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Panama City departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$525
Delta
Wed 2/4Fri 2/6
MEX - ECP • 2 stops
Cheapest one-way
Multiple Airlines
Fri 11/28
MEX - ECP • multi-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Mexico City to Panama City (MEX-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Panama City

Wed, Feb 4 - Fri, Feb 6
Delta Logo
8:35 am - 6:14 pmMEX-ECP
9h 39m2 stops
Delta Logo
6:00 am - 5:10 pmECP-MEX
11h 10m2 stops
$525Delta
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Wed, Feb 4 - Fri, Feb 6
Delta Logo
8:35 am - 6:14 pmMEX-ECP
9h 39m2 stops
Delta Logo
6:00 am - 12:55 pmECP-MEX
6h 55m1 stop
$526Delta
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Wed, Feb 4 - Fri, Feb 6
Delta Logo
2:10 pm - 10:40 pmMEX-ECP
8h 30m1 stop
Delta Logo
7:20 am - 3:15 pmECP-MEX
7h 55m1 stop
$528Delta
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Sun, Jan 25 - Fri, Jan 30
Delta Logo
10:10 am - 10:40 pmMEX-ECP
12h 30m2 stops
Delta Logo
12:15 pm - 8:50 pmECP-MEX
8h 35m1 stop
$546Delta
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Sat, Jan 24 - Fri, Jan 30
American Airlines Logo
12:25 am - 1:04 pmMEX-ECP
12h 39m2 stops
American Airlines Logo
12:03 pm - 12:10 amECP-MEX
12h 07m2 stops
$596American Airlines
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Booking Insights

KAYAK's insights & trends for Mexico City to Panama City flights

Get data-powered insights and trends into flights from Mexico City to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Mexico City and Panama City?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Mexico City to Panama City.

There is just one airline that flies from Mexico City to Panama City direct and that is United Airlines. The best round-trip deal found from United Airlines for the route is $468.

Find deals

Good to know

Low seasonJuly
Cheapest flight$525
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Mexico City to Panama City

When to book flights from Mexico City to Panama City

Are your dates flexible? Find out the best times to travel from Mexico City to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Panama City

  • What is the cheapest flight from Mexico City to Panama City?

    In the last 3 days, the lowest price for a flight from Mexico City to Panama City was $497 for a round-trip ticket.

  • Do I need a passport to fly between Mexico City and Panama City?

    A passport is required to fly from Mexico City to Panama City.

  • Which airports will I be using when flying from Mexico City to Panama City?

    Mexico City airport is called Mexico City Benito Juarez and the only airport in Panama City is Panama City NW Florida Beaches.

  • Which aircraft models fly most regularly from Mexico City to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Mexico City to Panama City?

    Star Alliance is the only airline alliance operating flights between Mexico City and Panama City.

  • How does KAYAK find such low prices on flights from Mexico City to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Mexico City to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9057 reviews
7.7Boarding
8.1Crew
7.1Entertainment
7.3Comfort
6.6Food
Airline reviews

Always wish for more healthy, gluten free options. We have to bring our own.

10.0 ExcellentClaire, Nov 2025ORD - PNS
Read more United Airlines reviews

Always wish for more healthy, gluten free options. We have to bring our own.

Flight left on time. Boarding was easy. Arrived to EWR 30 mins early. Luggage was deplaned in good time. Overall a very good experience.

Excellent all round, first time flying United. App is very helpful.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

The food and sitting need improvements. They were extremely bad.. If you choose to recline, there is no room for the passenger behind you. This is one of the worst sitting arrangements that I ever experience. The aircraft was not properly clean before boarding.

I liked the choice of lemon ginger tea. I think stewardesses can be more considerate of older people needs.

I love flying with United. Unfortunately, I flew on an older plane with minimal upgraded technology (no Bluetooth functionality or handy charging ports). Otherwise, the flight was great and even arrived early.

They changed my seats after I checked in and I was stressed from the time I saw that information until just before boarding, when the gate attendant fixed it, but it shouldn't have happened. And if it couldn't be prevented, then the people on the phone I spoke with should have done something to help, which they did not, nor did they offer me compensation, just meaningless apologies.

Smooth flight, especially take off and landing, and great crew on board. Really loved the stroopwaffles!

Its good expeince but in enternteiment please be like you tube the music i like or movie

Everything you need to know for your flight from Mexico City to Panama City

Information on your arrival and departure airports

Mexico City (MEX)
Panama City (ECP)