MEX - ECP

$644 Find Cheap Flights from Mexico City to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Panama City departing on 8/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$644
Aeromexico
Sun 8/2Sat 8/8
MEX - ECP • 2 stops
Top airlines
Aeromexico
Cheapest • from $644 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Mexico City and Panama City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $536 (round-trip)
Atlanta (ATL)
Shortest trip • 6h 39m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Mexico City to Panama City (MEX-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Panama City

Sun, Aug 2 - Sat, Aug 8
Aeromexico Logo
6:55 am - 7:36 pm
MEX
-
ECP
11h 41m
2 stops
Aeromexico Logo
6:00 am - 9:14 pm
ECP
-
MEX
16h 14m
1 stop
$644Aeromexico
Sun, Aug 2 - Sat, Aug 8
Aeromexico Logo
7:05 am - 7:36 pm
MEX
-
ECP
11h 31m
1 stop
Aeromexico Logo
6:00 am - 9:14 pm
ECP
-
MEX
16h 14m
1 stop
$705Aeromexico
Sat, Mar 28 - Sat, Apr 4
American Airlines Logo
5:00 am - 11:49 pm
MEX
-
ECP
17h 49m
2 stops
American Airlines Logo
3:38 pm - 10:20 am
ECP
-
MEX
19h 42m
1 stop
$776American Airlines
Thu, Apr 2 - Thu, Apr 9
United Airlines Logo
4:40 pm - 9:48 am
MEX
-
ECP
16h 08m
2 stops
United Airlines Logo
4:57 pm - 11:10 pm
ECP
-
MEX
7h 13m
1 stop
$843United Airlines
Sat, Mar 28 - Sat, Apr 4
American Airlines Logo
5:00 am - 11:49 pm
MEX
-
ECP
17h 49m
2 stops
American Airlines Logo
4:39 pm - 9:55 am
ECP
-
MEX
18h 16m
2 stops
$863American Airlines
Thu, Apr 2 - Thu, Apr 9
United Airlines Logo
4:40 am - 9:48 am
MEX
-
ECP
28h 08m
2 stops
United Airlines Logo
2:19 pm - 11:10 pm
ECP
-
MEX
33h 51m
2 stops
$901United Airlines
Sat, Mar 28 - Sat, Apr 4
United Airlines Logo
4:45 pm - 9:35 am
MEX
-
ECP
15h 50m
1 stop
United Airlines Logo
10:10 am - 3:40 pm
ECP
-
MEX
6h 30m
1 stop
$984United Airlines
Booking Insights

KAYAK's insights & trends for Mexico City to Panama City flights

Get data-powered insights and trends into flights from Mexico City to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Mexico City to Panama City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Mexico City to Panama City were found on Aeromexico ($644) and American Airlines ($776).

Good to know

Low seasonApril
Cheapest flight$644
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Mexico City to Panama City

When to book flights from Mexico City to Panama City

Are your dates flexible? Find out the best times to travel from Mexico City to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Panama City

  • What is the cheapest flight from Mexico City to Panama City?

    In the last 3 days, the lowest price for a flight from Mexico City to Panama City was $644 for a round-trip ticket.

  • Do I need a passport to fly between Mexico City and Panama City?

    A passport is required to fly from Mexico City to Panama City.

  • Which airports will I be using when flying from Mexico City to Panama City?

    Mexico City airport is called Mexico City Benito Juarez and the only airport in Panama City is Panama City NW Florida Beaches.

  • Which aircraft models fly most regularly from Mexico City to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Mexico City to Panama City?

    Star Alliance is the only airline alliance operating flights between Mexico City and Panama City.

  • How does KAYAK find such low prices on flights from Mexico City to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Mexico City to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9348 reviews
7.3Comfort
8.1Crew
7.7Boarding
6.6Food
7.1Entertainment
Airline reviews

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

10.0 ExcellentAnonymous, Feb 2026
DEN - RSW
Read more United Airlines reviews

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

I couldn’t make my first flight due to weather delays trapping us in the town we were in. Then I had to buy a new ticket

Much better than Spirit. I was please by the easy fast check in and boarding

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

Mean flight attendant. I wanted to reuse my plastic cup, but he (Matthew) said he can't for safety. I then said "I don't want water then" and he poured me a glass. I hope Matthew gets herpes and spends the rest of his life poor, lonely, and homeless.

I just think it’s unfortunate that Airlines have completely abandoned the idea of serving any kind of decent or even real food on flights, not even on a four hour flight!? Those days are gone, I guess.

Both flights delayed. 2nd flight over 3 hours late mechanical issues

Flight was delayed 45 minutes because originating flight was coming from Newark. No complimentary snacks were offered on this 5+ hour flight. No screens for the flight, but movies offered if you had already downloaded the United app (which I hadn't on my ipad). No USB ports, only a flimsy plug-in port near the bottom of the seat that was hard to see and kept coming unplugged.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Always wish for more healthy, gluten free options. We have to bring our own.

Everything you need to know for your flight from Mexico City to Panama City

Information on your arrival and departure airports