$340 Find Cheap Flights from Mexico to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results for flights to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to Panama City, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Mexico to Panama City

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico to Panama City

Mon, Dec 1 - Thu, Dec 4
Delta Logo
7:00 am - 5:53 pmMEX-ECP
10h 53m2 stops
Delta Logo
1:30 pm - 9:25 pmECP-MEX
7h 55m2 stops
$494Delta
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Thu, Oct 30 - Mon, Nov 3
United Airlines Logo
6:50 am - 1:57 pmMEX-ECP
6h 07m1 stop
United Airlines Logo
6:30 am - 6:55 pmECP-MEX
12h 25m1 stop
$499United Airlines
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Thu, Oct 30 - Mon, Nov 3
United Airlines Logo
9:05 am - 4:03 pmMEX-ECP
5h 58m1 stop
United Airlines Logo
6:30 am - 12:15 pmECP-MEX
5h 45m1 stop
$500United Airlines
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Thu, Oct 30 - Mon, Nov 3
United Airlines Logo
4:45 pm - 9:49 pmMEX-ECP
28h 04m1 stop
United Airlines Logo
6:30 am - 6:55 pmECP-MEX
12h 25m1 stop
$502United Airlines
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Sat, Nov 8 - Thu, Nov 13
Delta Logo
4:50 pm - 11:10 pmMEX-ECP
6h 20m1 stop
Delta Logo
6:00 am - 4:45 pmECP-MEX
10h 45m2 stops
$521Delta
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Sat, Nov 8 - Thu, Nov 13
United Airlines Logo
5:45 am - 9:19 amMEX-ECP
27h 34m1 stop
United Airlines Logo
3:00 pm - 12:10 amECP-MEX
9h 10m1 stop
$524United Airlines
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Mon, Dec 1 - Thu, Dec 4
United Airlines Logo
12:25 pm - 9:49 pmMEX-ECP
9h 24m1 stop
United Airlines Logo
5:00 pm - 6:55 pmECP-MEX
25h 55m1 stop
$525United Airlines
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Fri, Nov 7 - Thu, Nov 13
American Airlines Logo
12:25 am - 2:07 pmMEX-ECP
13h 42m2 stops
American Airlines Logo
6:43 am - 9:55 pmECP-MEX
15h 12m1 stop
$581American Airlines
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Wed, Oct 29 - Mon, Nov 3
WestJet Logo
1:10 am - 11:10 pmMEX-ECP
45h 00m2 stops
WestJet Logo
6:00 am - 2:45 pmECP-MEX
32h 45m2 stops
$1,389WestJet
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Sun, Nov 30 - Thu, Dec 4
WestJet Logo
1:55 am - 5:53 pmMEX-ECP
15h 58m2 stops
WestJet Logo
6:00 am - 1:00 amECP-MEX
43h 00m2 stops
$1,670WestJet
Find Deal
Booking Insights

KAYAK's insights & trends for flights to Panama City

Get data-powered insights and trends for flights to Panama City to help you find the cheapest flights, the best time to fly and much more.

How long is the flight to Panama City?

The duration of your flight to Panama City depends on your departure and arrival airports. Obviously, any flights that include a layover will also be longer. The most popular routes to Panama City on KAYAK are from Mexico City, which takes 5h 38m, Cancún, which takes 6h 14m, and Puerto Vallarta, which takes 14h 47m.

How many direct flights to Panama City are there each day?

There are around 34 direct flights from within Mexico to Panama City every day. Most flights depart in the morning, with 8:00 am the most common departure time and 54% of flights departing in the morning.

Good to know

Low seasonJuly
Cheapest flight$340
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Mexico City to Panama City

FAQs - booking Panama City flights

  • How far is Panama City NW Florida Beaches Airport from central Panama City?

    The city center of Panama City is 16 miles from Panama City NW Florida Beaches Airport.

  • What is the name of Panama City’s airport?

    Panama City is served by Panama City NW Florida Beaches Airport, also commonly referred to as NW Florida Beaches or Northwest Florida Beaches. The airport code is ECP.

  • What is the cheapest day to fly to Panama City?

    Based on KAYAK data, the cheapest day to fly to Panama City is Monday where round-trip tickets can be as cheap as $527. On the other hand, the most expensive day to fly is Thursday, where round-trip prices are $674 on average.

  • How does KAYAK find such low prices on flights to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many direct flights to Panama City are there each week?

    Each week there are around 236 direct flights from within Mexico to Panama City. The most common day for departures is Saturday, with 18% of flights taking off on this day.

Top tips for finding cheap flights to Panama City

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest Panama City flight deals.

Reviews of the top airline flying from Mexico to Panama City

 
See real verified KAYAK customer reviews for airlines flying to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Mexico to Panama City. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8915 reviews
7.7Boarding
7.3Comfort
7.1Entertainment
6.6Food
8.1Crew
Airline reviews

The food and sitting need improvements. They were extremely bad.. If you choose to recline, there is no room for the passenger behind you. This is one of the worst sitting arrangements that I ever experience. The aircraft was not properly clean before boarding.

4.0 OkayAnonymous, Aug 2025FRA - MCO
Read more United Airlines reviews

The food and sitting need improvements. They were extremely bad.. If you choose to recline, there is no room for the passenger behind you. This is one of the worst sitting arrangements that I ever experience. The aircraft was not properly clean before boarding.

I liked the choice of lemon ginger tea. I think stewardesses can be more considerate of older people needs.

I love flying with United. Unfortunately, I flew on an older plane with minimal upgraded technology (no Bluetooth functionality or handy charging ports). Otherwise, the flight was great and even arrived early.

They changed my seats after I checked in and I was stressed from the time I saw that information until just before boarding, when the gate attendant fixed it, but it shouldn't have happened. And if it couldn't be prevented, then the people on the phone I spoke with should have done something to help, which they did not, nor did they offer me compensation, just meaningless apologies.

Smooth flight, especially take off and landing, and great crew on board. Really loved the stroopwaffles!

Its good expeince but in enternteiment please be like you tube the music i like or movie

The crew was fantastic. They were there whenever we needed. The wifi didn’t work which was brutal on an 11 hour flight. The onboard entertainment was boring. Nothing of interest

Stewardess spilled orange juice on my clothes/seat no help no apology just threw napkins at me to clean the mess up. Not Happy.

My suitcase was destroyed. The top part where the handle is is completed broken. And unusable now.

I had a bad experience with the security at IAH and felt like a sardine on all 4 legs of my journey.

Traveling to a place near Panama City?

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Everything you need to know for your flight to Panama City

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